Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Gap junction 💬
 [1] ADRB1 💬 Amiodarone 💬 Amiodarone [2] 28, 127 💬
2 Gap junction 💬
 [1] ADRB1 💬 Atenolol 💬 Atenolol [1] 167 💬
3 Gap junction 💬
 [1] ADRB1 💬 Bisoprolol 💬 Bisoprolol [4] 58, 67, 86, 113 💬
4 Gap junction 💬
 [1] ADRB1 💬 Carvedilol 💬 Carvedilol [4] 57, 86, 113, 210 💬
5 Gap junction 💬
 [1] ADRB1 💬 Celiprolol 💬 Celiprolol [1] 168 💬
6 Gap junction 💬
 [1] ADRB1 💬 Dipivefrin 💬 Dipivefrin [1]  6  💬
7 Gap junction 💬
 [1] ADRB1 💬 Dobutamine 💬 Dobutamine [4] 57, 58, 86, 215 💬
8 Gap junction 💬
 [1] ADRB1 💬 Droxidopa 💬 Droxidopa [5]  5 ,  6 , 17, 169, 170 💬
9 Gap junction 💬
 [1] ADRB1 💬 Ephedrine 💬 Ephedrine [1] 11 💬
10 Gap junction 💬
 [1] ADRB1 💬 Epinephrine 💬 Epinephrine [3] 46, 70, 96 💬
11 Gap junction 💬
 [1] ADRB1 💬 Esmolol 💬 Esmolol [1] 58 💬
12 Gap junction 💬
 [1] ADRB1 💬 Metoprolol 💬 Metoprolol [6] 17, 57, 58, 113, 193, 226 💬
13 Gap junction 💬
 [1] ADRB1 💬 Nadolol 💬 Nadolol [1]  6  💬
14 Gap junction 💬
 [1] ADRB1 💬 Nebivolol 💬 Nebivolol [4] 17, 85, 113, 167 💬
15 Gap junction 💬
 [1] ADRB1 💬 Noradrenaline 💬 Norepinephrine [2] 22, 296 💬
16 Gap junction 💬
 [1] ADRB1 💬 Propranolol 💬 Propranolol [6]  6 , 158, 167, 227, 278, 296 💬
17 Gap junction 💬
 [1] ADRB1 💬 Pseudoephedrine 💬 Pseudoephedrine [1] 17 💬
18 Gap junction 💬
 [1] ADRB1 💬 Timolol 💬 Timolol [2] 157, 227 💬
19 Gap junction 💬
 [1] ADRB1 💬 Timolol 💬 Timolol [2] 157, 227 💬
20 Gap junction 💬
 [1] DRD1 💬 Tavapadon 💬 Tavapadon [1]  6  💬
21 Gap junction 💬
 [2] DRD1, DRD2 💬 Apomorphine 💬 Apomorphine [3]  5 ,  6 ,  7  💬
22 Gap junction 💬
 [2] DRD1, DRD2 💬 Dexpramipexole 💬 Dexpramipexole [1]  2  💬
23 Gap junction 💬
 [2] DRD1, DRD2 💬 Dopamine 💬 Dopamine [4]  6 ,  7 , 74, 299 💬
24 Gap junction 💬
 [2] DRD1, DRD2 💬 Flupentixol 💬 Flupentixol [1] 97 💬
25 Gap junction 💬
 [2] DRD1, DRD2 💬 Foslevodopa 💬 Foslevodopa [1]  6  💬
26 Gap junction 💬
 [2] DRD1, DRD2 💬 Levodopa 💬 Levodopa [6]  6 , 17, 90, 140, 164, 201 💬
27 Gap junction 💬
 [2] DRD1, DRD2 💬 Pergolide 💬 Pergolide [1]  6  💬
28 Gap junction 💬
 [1] DRD2 💬 Bromocriptine 💬 Bromocriptine [2]  6 , 74 💬
29 Gap junction 💬
 [1] DRD2 💬 Buspirone 💬 Buspirone [2]  6 , 51 💬
30 Gap junction 💬
 [1] DRD2 💬 Cabergoline 💬 Cabergoline [3]  6 , 74, 75 💬
31 Gap junction 💬
 [1] DRD2 💬 Domperidone 💬 Domperidone [5]  6 , 13, 17, 51, 230 💬
32 Gap junction 💬
 [1] DRD2 💬 Domperidone maleate 💬 Domperidone [5]  6 , 13, 17, 51, 230 💬
33 Gap junction 💬
 [1] DRD2 💬 Haloperidol 💬 Haloperidol [1]  8  💬
34 Gap junction 💬
 [1] DRD2 💬 Lisuride 💬 Lisuride [2]  6 , 86 💬
35 Gap junction 💬
 [1] DRD2 💬 Melperone 💬 Melperone [1]  6  💬
36 Gap junction 💬
 [1] DRD2 💬 Metoclopramide 💬 Metoclopramide [2] 46, 51 💬
37 Gap junction 💬
 [1] DRD2 💬 Pardoprunox 💬 Pardoprunox [1]  6  💬
38 Gap junction 💬
 [1] DRD2 💬 Pimozide 💬 Pimozide [1]  2  💬
39 Gap junction 💬
 [1] DRD2 💬 Piribedil 💬 Piribedil [1]  6  💬
40 Gap junction 💬
 [1] DRD2 💬 Pramipexole 💬 Pramipexole [3]  2 ,  6 , 20 💬
41 Gap junction 💬
 [1] DRD2 💬 Pridopidine 💬 Pridopidine [3]  2 ,  6 ,  8  💬
42 Gap junction 💬
 [1] DRD2 💬 Ropinirole 💬 Ropinirole [4]  2 ,  6 , 74, 309 💬
43 Gap junction 💬
 [1] DRD2 💬 Rotigotine 💬 Rotigotine [1]  6  💬
44 Gap junction 💬
 [1] DRD2 💬 Sulpiride 💬 Sulpiride [2]  6 , 70 💬
45 Gap junction 💬
 [1] DRD2 💬 Terguride 💬 Terguride [2] 51, 86 💬
46 Gap junction 💬
 [1] DRD2 💬 Tiapride 💬 Tiapride [1]  8  💬
47 Gap junction 💬
 [1] DRD2 💬 Trifluoperazine maleate 💬 Trifluoperazine [2] 283, 284 💬
48 Gap junction 💬
 [1] DRD2 💬 Trifluoperazine 💬 Trifluoperazine [2] 283, 284 💬
49 Gap junction 💬
 [2] DRD2, HTR2A 💬 Aripiprazole 💬 Aripiprazole [2]  6 , 206 💬
50 Gap junction 💬
 [2] DRD2, HTR2A 💬 Cariprazine 💬 Cariprazine [1] 21 💬
51 Gap junction 💬
 [2] DRD2, HTR2A 💬 Quetiapine 💬 Quetiapine [2]  6 , 13 💬
52 Gap junction 💬
 [2] DRD2, HTR2A 💬 Risperidone 💬 Risperidone [5]  8 , 156, 179, 187, 206 💬
53 Gap junction 💬
 [4] DRD2, HTR2A, HTR2B, HTR2C 💬 Chlorpromazine 💬 Chlorpromazine [1] 254 💬
54 Gap junction 💬
 [4] DRD2, HTR2A, HTR2B, HTR2C 💬 Iloperidone 💬 Iloperidone [1]  6  💬
55 Gap junction 💬
 [4] DRD2, HTR2A, HTR2B, HTR2C 💬 Olanzapine 💬 Olanzapine [2]  2 ,  8  💬
56 Gap junction 💬
 [1] EGFR 💬 Cetuximab 💬 Cetuximab [2] 51, 86 💬
57 Gap junction 💬
 [1] EGFR 💬 Erlotinib 💬 Erlotinib [1] 94 💬
58 Gap junction 💬
 [1] EGFR 💬 Gefitinib 💬 Gefitinib [1] 75 💬
59 Gap junction 💬
 [1] EGFR 💬 Icotinib 💬 Icotinib [1] 34 💬
60 Gap junction 💬
 [1] EGFR 💬 Lapatinib 💬 Lapatinib [3] 34, 74, 75 💬
61 Gap junction 💬
 [1] EGFR 💬 Neratinib 💬 Neratinib [1] 34 💬
62 Gap junction 💬
 [1] EGFR 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
63 Gap junction 💬
 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 Amyl nitrite 💬 Amyl Nitrite [1] 58 💬
64 Gap junction 💬
 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 Riociguat 💬 Riociguat [6] 51, 84, 86, 88, 225, 299 💬
65 Gap junction 💬
 [1] HTR2A 💬 Cisapride 💬 Cisapride [1] 13 💬
66 Gap junction 💬
 [1] HTR2A 💬 Cisapride 💬 Cisapride [1] 13 💬
67 Gap junction 💬
 [1] HTR2A 💬 Nelotanserin 💬 Nelotanserin [1]  6  💬
68 Gap junction 💬
 [3] HTR2A, HTR2B, HTR2C 💬 Trazodone 💬 Trazodone [1]  2  💬
69 Gap junction 💬
 [2] HTR2A, HTR2C 💬 Clozapine 💬 Clozapine [1]  6  💬
70 Gap junction 💬
 [2] HTR2A, HTR2C 💬 Fenfluramine 💬 Fenfluramine [4] 140, 144, 145, 149 💬
71 Gap junction 💬
 [1] HTR2C 💬 Agomelatine 💬 Agomelatine [1]  6  💬
72 Gap junction 💬
 [2] MAP2K1, MAP2K2 💬 Binimetinib 💬 Binimetinib [1] 34 💬
73 Gap junction 💬
 [2] MAP2K1, MAP2K2 💬 Cobimetinib 💬 Cobimetinib [1] 280 💬
74 Gap junction 💬
 [2] MAP2K1, MAP2K2 💬 Mirdametinib 💬 Mirdametinib [1] 34 💬
75 Gap junction 💬
 [2] MAP2K1, MAP2K2 💬 Selumetinib 💬 Selumetinib [1] 34 💬
76 Gap junction 💬
 [2] MAP2K1, MAP2K2 💬 Trametinib 💬 Trametinib [4]  2 , 34, 279, 280 💬
77 Gap junction 💬
 [1] PDGFRA 💬 Imatinib 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
78 Gap junction 💬
 [2] PDGFRA, PDGFRB 💬 Nilotinib 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
79 Gap junction 💬
 [2] PDGFRA, PDGFRB 💬 Nintedanib 💬 Nintedanib [5] 51, 85, 89, 227, 228 💬
80 Gap junction 💬
 [2] PDGFRA, PDGFRB 💬 Sunitinib 💬 Sunitinib [2] 28, 34 💬
81 Gap junction 💬
 [2] PDGFRB, RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
82 Gap junction 💬
 [2] PDGFRB, SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
83 Gap junction 💬
 [2] PDGFRB, SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
84 Gap junction 💬
 [1] PRKCB 💬 Enzastaurin 💬 Enzastaurin [1] 168 💬
85 Gap junction 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
86 Gap junction 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
87 Gap junction 💬
 [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 Belantamab mafodotin 💬 Belantamab mafodotin [1] 28 💬
88 Gap junction 💬
 [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 Brentuximab vedotin 💬 Brentuximab vedotin [2] 49, 51 💬
89 Gap junction 💬
 [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 Colchicine 💬 Colchicine [7]  2 , 42, 46, 56, 93, 210, 266 💬
90 Gap junction 💬
 [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 Paclitaxel 💬 Paclitaxel [2] 46, 85 💬
91 Gap junction 💬
 [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 Vinblastine 💬 Vinblastine [2] 34, 65 💬
92 Gap junction 💬
 [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 Vincristine 💬 Vincristine [4] 26, 34, 65, 331 💬