Target Gene/Pathway Pathway / Gene
Search results
| No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related  | KEGG GENES | KEGG DRUG | DrugBank | Disease ID | 
|---|---|---|---|---|---|
| 1 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases  | 
BCL2 [1] BCL2 💬
 | 
Venetoclax  Venetoclax  💬
 | Venetoclax | 028 [1] 28 💬
 | 
| 2 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases  | 
CASP9 [1] CASP9 💬
 | 
Rimiducid  Rimiducid  💬
 | Rimiducid | 019 [6] 19, 60, 65, 284, 285, 326 💬
 | 
| 3 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases  | 
CCL2 [4] CCL2, IL1B, IL6, TNF 💬
 | 
Pirfenidone  Pirfenidone  💬
 | Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
 | 
| 4 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases  | 
CD40 [1] CD40 💬
 | 
Bleselumab  Bleselumab  💬
 | Bleselumab | 222 [1] 222 💬
 | 
| 5 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases  | 
CD40 [1] CD40 💬
 | 
Iscalimab  Iscalimab  💬
 | Iscalimab | 049 [2] 49, 53 💬
 | 
| 6 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases  | 
CD40 [1] CD40 💬
 | 
Ravagalimab  Ravagalimab  💬
 | Ravagalimab | 053 [2] 53, 97 💬
 | 
| 7 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases  | 
CD40LG [1] CD40LG 💬
 | 
Toralizumab  Toralizumab  💬
 | Toralizumab | 063 [1] 63 💬
 | 
| 8 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases  | 
IFNA1 [13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬
 | 
Rontalizumab  Rontalizumab  💬
 | Rontalizumab | 049 [1] 49 💬
 | 
| 9 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases  | 
IFNA1 [13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬
 | 
Sifalimumab  Sifalimumab  💬
 | Sifalimumab | 049 [1] 49 💬
 | 
| 10 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases  | 
IL12A [2] IL12A, IL12B 💬
 | 
Ustekinumab  Ustekinumab  💬
 | Ustekinumab | 037 [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
 | 
| 11 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases  | 
IL1B [1] IL1B 💬
 | 
Canakinumab  Canakinumab  💬
 | Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
 | 
| 12 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases  | 
IL1B [1] IL1B 💬
 | 
Gevokizumab  Gevokizumab  💬
 | Gevokizumab | 041 [4] 41, 50, 56, 269 💬
 | 
| 13 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases  | 
IL1B [1] IL1B 💬
 | 
Rilonacept  Rilonacept  💬
 | Rilonacept | 051 [4] 51, 106, 107, 266 💬
 | 
| 14 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases  | 
IL6 [1] IL6 💬
 | 
Olokizumab  Olokizumab  💬
 | Olokizumab | 046 [2] 46, 96 💬
 | 
| 15 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases  | 
IL6 [1] IL6 💬
 | 
Siltuximab  Siltuximab  💬
 | Siltuximab | 028 [2] 28, 331 💬
 | 
| 16 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases  | 
IL6 [1] IL6 💬
 | 
Sirukumab  Sirukumab  💬
 | Sirukumab | 041 [2] 41, 46 💬
 | 
| 17 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases  | 
IL6 [2] IL6, TNF 💬
 | 
Pomalidomide  Pomalidomide  💬
 | Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
 | 
| 18 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases  | 
JAK2 [1] JAK2 💬
 | 
Baricitinib  Baricitinib  💬
 | Baricitinib | 002 [13]  2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
 | 
| 19 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases  | 
JAK2 [1] JAK2 💬
 | 
Peficitinib  Peficitinib  💬
 | Peficitinib | 046 [1] 46 💬
 | 
| 20 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases  | 
JAK2 [1] JAK2 💬
 | 
Ruxolitinib  Ruxolitinib  💬
 | Ruxolitinib | 060 [3] 60, 65, 228 💬
 | 
| 21 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases  | 
JAK2 [1] JAK2 💬
 | 
Tofacitinib  Tofacitinib  💬
 | Tofacitinib | 011 [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬
 | 
| 22 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases  | 
MAP3K5 [1] MAP3K5 💬
 | 
Selonsertib  Selonsertib  💬
 | Selonsertib | 086 [1] 86 💬
 | 
| 23 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases  | 
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
 | 
Losmapimod  Losmapimod  💬
 | Losmapimod | 113 [2] 113, 222 💬
 | 
| 24 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases  | 
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
 | 
Neflamapimod  Neflamapimod  💬
 | Neflamapimod | 008 [1]  8  💬
 | 
| 25 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases  | 
NFE2L2 [1] NFE2L2 💬
 | 
Omaveloxolone  Omaveloxolone  💬
 | Omaveloxolone | 018 [1] 18 💬
 | 
| 26 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases  | 
NFKB1 [1] NFKB1 💬
 | 
Iguratimod  Iguratimod  💬
 | Iguratimod | 046 [5] 46, 51, 53, 271, 300 💬
 | 
| 27 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases  | 
PIK3CA [1] PIK3CA 💬
 | 
Alpelisib  Alpelisib  💬
 | Alpelisib | 138 [1] 138 💬
 | 
| 28 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases  | 
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬
 | 
Leniolisib  Leniolisib  💬
 | Leniolisib | 053 [2] 53, 65 💬
 | 
| 29 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases  | 
PIK3CD [1] PIK3CD 💬
 | 
Parsaclisib  Parsaclisib  💬
 | Parsaclisib | 035 [3] 35, 53, 61 💬
 | 
| 30 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases  | 
PPARG [1] PPARG 💬
 | 
Bocidelpar  Bocidelpar  💬
 | Bocidelpar | 113 [1] 113 💬
 | 
| 31 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases  | 
PPARG [1] PPARG 💬
 | 
Leriglitazone  Leriglitazone  💬
 | Leriglitazone | 020 [1] 20 💬
 | 
| 32 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases  | 
PPARG [1] PPARG 💬
 | 
Pioglitazone  Pioglitazone  💬
 | Pioglitazone | 002 [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
 | 
| 33 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases  | 
PPARG [1] PPARG 💬
 | 
Rosiglitazone  Rosiglitazone  💬
 | Rosiglitazone | 046 [5] 46, 75, 97, 222, 265 💬
 | 
| 34 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases  | 
PPARG [1] PPARG 💬
 | 
Seladelpar  Seladelpar  💬
 | Seladelpar | 093 [2] 93, 94 💬
 | 
| 35 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases  | 
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
 | 
Cyclosporine  Cyclosporine  💬
 | Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
 | 
| 36 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases  | 
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
 | 
Pimecrolimus  Pimecrolimus  💬
 | Pimecrolimus | 160 [1] 160 💬
 | 
| 37 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases  | 
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
 | 
Tacrolimus  Tacrolimus  💬
 | Tacrolimus | 002 [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
 | 
| 38 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases  | 
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
 | 
Tacrolimus  Tacrolimus  💬
 | Tacrolimus | 002 [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
 | 
| 39 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases  | 
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
 | 
Voclosporin  Voclosporin  💬
 | Voclosporin | 049 [2] 49, 222 💬
 | 
| 40 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases  | 
RELA [1] RELA 💬
 | 
Edasalonexent  Edasalonexent  💬
 | Edasalonexent | 113 [1] 113 💬
 | 
| 41 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases  | 
ROCK2 [1] ROCK2 💬
 | 
Belumosudil  Belumosudil  💬
 | Belumosudil | 051 [2] 51, 85 💬
 | 
| 42 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases  | 
ROCK2 [1] ROCK2 💬
 | 
Fasudil  Fasudil  💬
 | Fasudil | 002 [4]  2 ,  5 ,  7 , 51 💬
 | 
| 43 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases  | 
RXRA [3] RXRA, RXRB, RXRG 💬
 | 
Acitretin  Acitretin  💬
 | Acitretin | 037 [1] 37 💬
 | 
| 44 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases  | 
RXRA [3] RXRA, RXRB, RXRG 💬
 | 
Alitretinoin  Alitretinoin  💬
 | Alitretinoin | 049 [1] 49 💬
 | 
| 45 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases  | 
RXRA [3] RXRA, RXRB, RXRG 💬
 | 
Bexarotene  Bexarotene  💬
 | Bexarotene | 013 [2] 13, 75 💬
 | 
| 46 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases  | 
SRC [1] SRC 💬
 | 
Bosutinib  Bosutinib  💬
 | Bosutinib | 002 [2]  2 , 67 💬
 | 
| 47 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases  | 
SRC [1] SRC 💬
 | 
Dasatinib  Dasatinib  💬
 | Dasatinib | 051 [2] 51, 85 💬
 | 
| 48 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases  | 
SRC [1] SRC 💬
 | 
Dasatinib  Dasatinib  💬
 | Dasatinib | 051 [2] 51, 85 💬
 | 
| 49 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases  | 
SRC [1] SRC 💬
 | 
Saracatinib  Saracatinib  💬
 | Saracatinib | 006 [3]  6 , 89, 272 💬
 | 
| 50 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases  | 
TNF [1] TNF 💬
 | 
Adalimumab  Adalimumab  💬
 | Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
 | 
| 51 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases  | 
TNF [1] TNF 💬
 | 
Certolizumab pegol  Certolizumab pegol  💬
 | Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
 | 
| 52 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases  | 
TNF [1] TNF 💬
 | 
Etanercept  Etanercept  💬
 | Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
 | 
| 53 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases  | 
TNF [1] TNF 💬
 | 
Golimumab  Golimumab  💬
 | Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
 | 
| 54 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases  | 
TNF [1] TNF 💬
 | 
Infliximab  Infliximab  💬
 | Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
 | 
| 55 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases  | 
TNF [1] TNF 💬
 | 
Lenalidomide  Lenalidomide  💬
 | Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
 | 
| 56 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases  | 
TNF [1] TNF 💬
 | 
Ozoralizumab  Ozoralizumab  💬
 | Ozoralizumab | 046 [1] 46 💬
 | 
| 57 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases  | 
TNF [1] TNF 💬
 | 
Pegsunercept  Pegsunercept  💬
 | Pegsunercept | 046 [1] 46 💬
 | 
| 58 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases  | 
TNF [1] TNF 💬
 | 
Thalidomide  Thalidomide  💬
 | Thalidomide | 002 [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
 |