Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Long-term potentiation 💬
 [1] BRAF 💬 Dabrafenib 💬 Dabrafenib [1] 34 💬
2 Long-term potentiation 💬
 [2] BRAF, RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
3 Long-term potentiation 💬
 [1] CACNA1C 💬 Amlodipine 💬 Amlodipine [4] 13, 51, 67, 298 💬
4 Long-term potentiation 💬
 [1] CACNA1C 💬 Cilnidipine 💬 Cilnidipine [1] 67 💬
5 Long-term potentiation 💬
 [1] CACNA1C 💬 Diltiazem 💬 Diltiazem [3] 51, 58, 86 💬
6 Long-term potentiation 💬
 [1] CACNA1C 💬 Isradipine 💬 Isradipine [1]  6  💬
7 Long-term potentiation 💬
 [1] CACNA1C 💬 Nicardipine 💬 Nicardipine [2] 70, 86 💬
8 Long-term potentiation 💬
 [1] CACNA1C 💬 Nifedipine 💬 Nifedipine [2] 50, 81 💬
9 Long-term potentiation 💬
 [1] CACNA1C 💬 Nilvadipine 💬 Nilvadipine [1] 90 💬
10 Long-term potentiation 💬
 [1] CACNA1C 💬 Perhexiline 💬 Perhexiline [2] 58, 272 💬
11 Long-term potentiation 💬
 [1] CACNA1C 💬 Propiverine 💬 Propiverine [1] 226 💬
12 Long-term potentiation 💬
 [1] CACNA1C 💬 Verapamil 💬 Verapamil [4] 58, 96, 140, 167 💬
13 Long-term potentiation 💬
 [3] CACNA1C, GRIA1, GRIA2 💬 Topiramate 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
14 Long-term potentiation 💬
 [2] GRIA1, GRIA2 💬 Perampanel 💬 Perampanel [3]  2 ,  6 , 144 💬
15 Long-term potentiation 💬
 [2] GRIA1, GRIA2 💬 Talampanel 💬 Talampanel [2]  2 ,  6  💬
16 Long-term potentiation 💬
 [7] GRIA1, GRIA2, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Riluzole 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
17 Long-term potentiation 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Acamprosate 💬 Acamprosate [2]  6 , 206 💬
18 Long-term potentiation 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Amantadine 💬 Amantadine [4]  6 ,  8 , 13, 127 💬
19 Long-term potentiation 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Dextromethorphan 💬 Dextromethorphan [11]  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
20 Long-term potentiation 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Esketamine 💬 Esketamine [3]  2 ,  4 , 70 💬
21 Long-term potentiation 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Ketamine 💬 Ketamine [8]  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬
22 Long-term potentiation 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Latrepirdine 💬 Latrepirdine [1]  8  💬
23 Long-term potentiation 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Memantine 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
24 Long-term potentiation 💬
 [2] MAP2K1, MAP2K2 💬 Binimetinib 💬 Binimetinib [1] 34 💬
25 Long-term potentiation 💬
 [2] MAP2K1, MAP2K2 💬 Cobimetinib 💬 Cobimetinib [1] 280 💬
26 Long-term potentiation 💬
 [2] MAP2K1, MAP2K2 💬 Mirdametinib 💬 Mirdametinib [1] 34 💬
27 Long-term potentiation 💬
 [2] MAP2K1, MAP2K2 💬 Selumetinib 💬 Selumetinib [1] 34 💬
28 Long-term potentiation 💬
 [2] MAP2K1, MAP2K2 💬 Trametinib 💬 Trametinib [4]  2 , 34, 279, 280 💬
29 Long-term potentiation 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Cyclosporine 💬 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
30 Long-term potentiation 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Pimecrolimus 💬 Pimecrolimus [1] 160 💬
31 Long-term potentiation 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
32 Long-term potentiation 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
33 Long-term potentiation 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Voclosporin 💬 Voclosporin [2] 49, 222 💬
34 Long-term potentiation 💬
 [1] PRKCB 💬 Enzastaurin 💬 Enzastaurin [1] 168 💬