Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Primary immunodeficiency 💬
 [1] BTK 💬 Acalabrutinib 💬 Acalabrutinib [2] 46, 61 💬
2 Primary immunodeficiency 💬
 [1] BTK 💬 Branebrutinib 💬 Branebrutinib [3] 46, 49, 53 💬
3 Primary immunodeficiency 💬
 [1] BTK 💬 Evobrutinib 💬 Evobrutinib [3] 13, 46, 49 💬
4 Primary immunodeficiency 💬
 [1] BTK 💬 Fenebrutinib 💬 Fenebrutinib [1] 13 💬
5 Primary immunodeficiency 💬
 [1] BTK 💬 Ibrutinib 💬 Ibrutinib [3] 28, 60, 61 💬
6 Primary immunodeficiency 💬
 [1] BTK 💬 Orelabrutinib 💬 Orelabrutinib [4] 13, 49, 61, 63 💬
7 Primary immunodeficiency 💬
 [1] BTK 💬 Remibrutinib 💬 Remibrutinib [2] 13, 53 💬
8 Primary immunodeficiency 💬
 [1] BTK 💬 Zanubrutinib 💬 Zanubrutinib [5] 13, 63, 222, 300, 331 💬
9 Primary immunodeficiency 💬
 [1] CD19 💬 Inebilizumab 💬 Inebilizumab [4] 11, 13, 51, 300 💬
10 Primary immunodeficiency 💬
 [1] CD19 💬 Obexelimab 💬 Obexelimab [1] 300 💬
11 Primary immunodeficiency 💬
 [2] CD3D, CD3E 💬 Otelixizumab 💬 Otelixizumab [1] 46 💬
12 Primary immunodeficiency 💬
 [2] CD3D, CD3E 💬 Visilizumab 💬 Visilizumab [2] 96, 97 💬
13 Primary immunodeficiency 💬
 [1] CD3E 💬 Mosunetuzumab 💬 Mosunetuzumab [1] 49 💬
14 Primary immunodeficiency 💬
 [1] CD4 💬 Zanolimumab 💬 Zanolimumab [1] 46 💬
15 Primary immunodeficiency 💬
 [1] CD40 💬 Bleselumab 💬 Bleselumab [1] 222 💬
16 Primary immunodeficiency 💬
 [1] CD40 💬 Iscalimab 💬 Iscalimab [2] 49, 53 💬
17 Primary immunodeficiency 💬
 [1] CD40 💬 Ravagalimab 💬 Ravagalimab [2] 53, 97 💬
18 Primary immunodeficiency 💬
 [1] CD40LG 💬 Toralizumab 💬 Toralizumab [1] 63 💬
19 Primary immunodeficiency 💬
 [1] IL2RG 💬 Aldesleukin 💬 Aldesleukin [6]  2 , 35, 49, 65, 96, 97 💬
20 Primary immunodeficiency 💬
 [1] JAK3 💬 Peficitinib 💬 Peficitinib [1] 46 💬
21 Primary immunodeficiency 💬
 [1] JAK3 💬 Tofacitinib 💬 Tofacitinib [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬
22 Primary immunodeficiency 💬
 [1] LCK 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
23 Primary immunodeficiency 💬
 [1] LCK 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
24 Primary immunodeficiency 💬
 [1] TNFRSF13C 💬 Ianalumab 💬 Ianalumab [7] 35, 46, 49, 53, 61, 63, 95 💬