Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Adrenergic signaling in cardiomyocytes 💬
 [1] ADRA1A 💬 Alfuzosin 💬 Alfuzosin [1] 13 💬
2 Adrenergic signaling in cardiomyocytes 💬
 [1] ADRA1A 💬 Silodosin 💬 Silodosin [2]  6 , 13 💬
3 Adrenergic signaling in cardiomyocytes 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Doxazosin 💬 Doxazosin [2] 57, 67 💬
4 Adrenergic signaling in cardiomyocytes 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Methylergometrine 💬 Methylergometrine [1] 280 💬
5 Adrenergic signaling in cardiomyocytes 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Midodrine 💬 Midodrine [3]  6 , 17, 58 💬
6 Adrenergic signaling in cardiomyocytes 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Olanzapine 💬 Olanzapine [2]  2 ,  8  💬
7 Adrenergic signaling in cardiomyocytes 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Phenylephrine 💬 Phenylephrine [1] 22 💬
8 Adrenergic signaling in cardiomyocytes 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Tamsulosin 💬 Tamsulosin [1] 13 💬
9 Adrenergic signaling in cardiomyocytes 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Terazosin 💬 Terazosin [1]  6  💬
10 Adrenergic signaling in cardiomyocytes 💬
 [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 Carvedilol 💬 Carvedilol [4] 57, 86, 113, 210 💬
11 Adrenergic signaling in cardiomyocytes 💬
 [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 Dipivefrin 💬 Dipivefrin [1]  6  💬
12 Adrenergic signaling in cardiomyocytes 💬
 [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 Droxidopa 💬 Droxidopa [5]  5 ,  6 , 17, 169, 170 💬
13 Adrenergic signaling in cardiomyocytes 💬
 [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 Ephedrine 💬 Ephedrine [1] 11 💬
14 Adrenergic signaling in cardiomyocytes 💬
 [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 Epinephrine 💬 Epinephrine [3] 46, 70, 96 💬
15 Adrenergic signaling in cardiomyocytes 💬
 [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 Noradrenaline 💬 Norepinephrine [2] 22, 296 💬
16 Adrenergic signaling in cardiomyocytes 💬
 [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 Pseudoephedrine 💬 Pseudoephedrine [1] 17 💬
17 Adrenergic signaling in cardiomyocytes 💬
 [6] ADRA1A, ADRA1B, ADRA1D, ADRB1, KCNQ1, SCN5A 💬 Amiodarone 💬 Amiodarone [2] 28, 127 💬
18 AMPK signaling pathway 💬
 [1] ADRA1A 💬 Alfuzosin 💬 Alfuzosin [1] 13 💬
19 AMPK signaling pathway 💬
 [1] ADRA1A 💬 Amiodarone 💬 Amiodarone [2] 28, 127 💬
20 AMPK signaling pathway 💬
 [1] ADRA1A 💬 Carvedilol 💬 Carvedilol [4] 57, 86, 113, 210 💬
21 AMPK signaling pathway 💬
 [1] ADRA1A 💬 Dipivefrin 💬 Dipivefrin [1]  6  💬
22 AMPK signaling pathway 💬
 [1] ADRA1A 💬 Doxazosin 💬 Doxazosin [2] 57, 67 💬
23 AMPK signaling pathway 💬
 [1] ADRA1A 💬 Droxidopa 💬 Droxidopa [5]  5 ,  6 , 17, 169, 170 💬
24 AMPK signaling pathway 💬
 [1] ADRA1A 💬 Ephedrine 💬 Ephedrine [1] 11 💬
25 AMPK signaling pathway 💬
 [1] ADRA1A 💬 Epinephrine 💬 Epinephrine [3] 46, 70, 96 💬
26 AMPK signaling pathway 💬
 [1] ADRA1A 💬 Methylergometrine 💬 Methylergometrine [1] 280 💬
27 AMPK signaling pathway 💬
 [1] ADRA1A 💬 Midodrine 💬 Midodrine [3]  6 , 17, 58 💬
28 AMPK signaling pathway 💬
 [1] ADRA1A 💬 Noradrenaline 💬 Norepinephrine [2] 22, 296 💬
29 AMPK signaling pathway 💬
 [1] ADRA1A 💬 Olanzapine 💬 Olanzapine [2]  2 ,  8  💬
30 AMPK signaling pathway 💬
 [1] ADRA1A 💬 Phenylephrine 💬 Phenylephrine [1] 22 💬
31 AMPK signaling pathway 💬
 [1] ADRA1A 💬 Pseudoephedrine 💬 Pseudoephedrine [1] 17 💬
32 AMPK signaling pathway 💬
 [1] ADRA1A 💬 Silodosin 💬 Silodosin [2]  6 , 13 💬
33 AMPK signaling pathway 💬
 [1] ADRA1A 💬 Tamsulosin 💬 Tamsulosin [1] 13 💬
34 AMPK signaling pathway 💬
 [1] ADRA1A 💬 Terazosin 💬 Terazosin [1]  6  💬
35 Calcium signaling pathway 💬
 [1] ADRA1A 💬 Alfuzosin 💬 Alfuzosin [1] 13 💬
36 Calcium signaling pathway 💬
 [1] ADRA1A 💬 Silodosin 💬 Silodosin [2]  6 , 13 💬
37 Calcium signaling pathway 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Doxazosin 💬 Doxazosin [2] 57, 67 💬
38 Calcium signaling pathway 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Methylergometrine 💬 Methylergometrine [1] 280 💬
39 Calcium signaling pathway 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Midodrine 💬 Midodrine [3]  6 , 17, 58 💬
40 Calcium signaling pathway 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Phenylephrine 💬 Phenylephrine [1] 22 💬
41 Calcium signaling pathway 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Tamsulosin 💬 Tamsulosin [1] 13 💬
42 Calcium signaling pathway 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Terazosin 💬 Terazosin [1]  6  💬
43 Calcium signaling pathway 💬
 [4] ADRA1A, ADRA1B, ADRA1D, ADRB1 💬 Amiodarone 💬 Amiodarone [2] 28, 127 💬
44 Calcium signaling pathway 💬
 [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 Carvedilol 💬 Carvedilol [4] 57, 86, 113, 210 💬
45 Calcium signaling pathway 💬
 [6] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 Dipivefrin 💬 Dipivefrin [1]  6  💬
46 Calcium signaling pathway 💬
 [6] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 Droxidopa 💬 Droxidopa [5]  5 ,  6 , 17, 169, 170 💬
47 Calcium signaling pathway 💬
 [6] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 Ephedrine 💬 Ephedrine [1] 11 💬
48 Calcium signaling pathway 💬
 [6] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 Epinephrine 💬 Epinephrine [3] 46, 70, 96 💬
49 Calcium signaling pathway 💬
 [6] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 Noradrenaline 💬 Norepinephrine [2] 22, 296 💬
50 Calcium signaling pathway 💬
 [6] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 Pseudoephedrine 💬 Pseudoephedrine [1] 17 💬
51 Calcium signaling pathway 💬
 [8] ADRA1A, ADRA1B, ADRA1D, HRH1, HTR2A, HTR2B, HTR2C, HTR6 💬 Olanzapine 💬 Olanzapine [2]  2 ,  8  💬
52 cGMP-PKG signaling pathway 💬
 [1] ADRA1A 💬 Alfuzosin 💬 Alfuzosin [1] 13 💬
53 cGMP-PKG signaling pathway 💬
 [1] ADRA1A 💬 Silodosin 💬 Silodosin [2]  6 , 13 💬
54 cGMP-PKG signaling pathway 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Doxazosin 💬 Doxazosin [2] 57, 67 💬
55 cGMP-PKG signaling pathway 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Midodrine 💬 Midodrine [3]  6 , 17, 58 💬
56 cGMP-PKG signaling pathway 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Olanzapine 💬 Olanzapine [2]  2 ,  8  💬
57 cGMP-PKG signaling pathway 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Phenylephrine 💬 Phenylephrine [1] 22 💬
58 cGMP-PKG signaling pathway 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Tamsulosin 💬 Tamsulosin [1] 13 💬
59 cGMP-PKG signaling pathway 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Terazosin 💬 Terazosin [1]  6  💬
60 cGMP-PKG signaling pathway 💬
 [6] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C 💬 Methylergometrine 💬 Methylergometrine [1] 280 💬
61 cGMP-PKG signaling pathway 💬
 [9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 Dipivefrin 💬 Dipivefrin [1]  6  💬
62 cGMP-PKG signaling pathway 💬
 [9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 Droxidopa 💬 Droxidopa [5]  5 ,  6 , 17, 169, 170 💬
63 cGMP-PKG signaling pathway 💬
 [9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 Ephedrine 💬 Ephedrine [1] 11 💬
64 cGMP-PKG signaling pathway 💬
 [9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 Epinephrine 💬 Epinephrine [3] 46, 70, 96 💬
65 cGMP-PKG signaling pathway 💬
 [9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 Noradrenaline 💬 Norepinephrine [2] 22, 296 💬
66 cGMP-PKG signaling pathway 💬
 [9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 Pseudoephedrine 💬 Pseudoephedrine [1] 17 💬
67 cGMP-PKG signaling pathway 💬
 [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 Carvedilol 💬 Carvedilol [4] 57, 86, 113, 210 💬
68 cGMP-PKG signaling pathway 💬
 [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, KCNJ8 💬 Amiodarone 💬 Amiodarone [2] 28, 127 💬
69 Neuroactive ligand-receptor interaction 💬
 [1] ADRA1A 💬 Alfuzosin 💬 Alfuzosin [1] 13 💬
70 Neuroactive ligand-receptor interaction 💬
 [1] ADRA1A 💬 Silodosin 💬 Silodosin [2]  6 , 13 💬
71 Neuroactive ligand-receptor interaction 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Doxazosin 💬 Doxazosin [2] 57, 67 💬
72 Neuroactive ligand-receptor interaction 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Midodrine 💬 Midodrine [3]  6 , 17, 58 💬
73 Neuroactive ligand-receptor interaction 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Phenylephrine 💬 Phenylephrine [1] 22 💬
74 Neuroactive ligand-receptor interaction 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Tamsulosin 💬 Tamsulosin [1] 13 💬
75 Neuroactive ligand-receptor interaction 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Terazosin 💬 Terazosin [1]  6  💬
76 Neuroactive ligand-receptor interaction 💬
 [6] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C 💬 Methylergometrine 💬 Methylergometrine [1] 280 💬
77 Neuroactive ligand-receptor interaction 💬
 [9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 Dipivefrin 💬 Dipivefrin [1]  6  💬
78 Neuroactive ligand-receptor interaction 💬
 [9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 Droxidopa 💬 Droxidopa [5]  5 ,  6 , 17, 169, 170 💬
79 Neuroactive ligand-receptor interaction 💬
 [9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 Ephedrine 💬 Ephedrine [1] 11 💬
80 Neuroactive ligand-receptor interaction 💬
 [9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 Epinephrine 💬 Epinephrine [3] 46, 70, 96 💬
81 Neuroactive ligand-receptor interaction 💬
 [9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 Noradrenaline 💬 Norepinephrine [2] 22, 296 💬
82 Neuroactive ligand-receptor interaction 💬
 [9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 Pseudoephedrine 💬 Pseudoephedrine [1] 17 💬
83 Neuroactive ligand-receptor interaction 💬
 [4] ADRA1A, ADRA1B, ADRA1D, ADRB1 💬 Amiodarone 💬 Amiodarone [2] 28, 127 💬
84 Neuroactive ligand-receptor interaction 💬
 [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 Carvedilol 💬 Carvedilol [4] 57, 86, 113, 210 💬
85 Neuroactive ligand-receptor interaction 💬
 [11] ADRA1A, ADRA1B, ADRA1D, DRD2, DRD3, DRD4, HRH1, HTR2A, HTR2B, HTR2C, HTR6 💬 Olanzapine 💬 Olanzapine [2]  2 ,  8  💬
86 Salivary secretion 💬
 [1] ADRA1A 💬 Alfuzosin 💬 Alfuzosin [1] 13 💬
87 Salivary secretion 💬
 [1] ADRA1A 💬 Silodosin 💬 Silodosin [2]  6 , 13 💬
88 Salivary secretion 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Doxazosin 💬 Doxazosin [2] 57, 67 💬
89 Salivary secretion 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Methylergometrine 💬 Methylergometrine [1] 280 💬
90 Salivary secretion 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Midodrine 💬 Midodrine [3]  6 , 17, 58 💬
91 Salivary secretion 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Olanzapine 💬 Olanzapine [2]  2 ,  8  💬
92 Salivary secretion 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Phenylephrine 💬 Phenylephrine [1] 22 💬
93 Salivary secretion 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Tamsulosin 💬 Tamsulosin [1] 13 💬
94 Salivary secretion 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Terazosin 💬 Terazosin [1]  6  💬
95 Salivary secretion 💬
 [4] ADRA1A, ADRA1B, ADRA1D, ADRB1 💬 Amiodarone 💬 Amiodarone [2] 28, 127 💬
96 Salivary secretion 💬
 [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 Carvedilol 💬 Carvedilol [4] 57, 86, 113, 210 💬
97 Salivary secretion 💬
 [6] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 Dipivefrin 💬 Dipivefrin [1]  6  💬
98 Salivary secretion 💬
 [6] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 Droxidopa 💬 Droxidopa [5]  5 ,  6 , 17, 169, 170 💬
99 Salivary secretion 💬
 [6] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 Ephedrine 💬 Ephedrine [1] 11 💬
100 Salivary secretion 💬
 [6] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 Epinephrine 💬 Epinephrine [3] 46, 70, 96 💬
101 Salivary secretion 💬
 [6] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 Noradrenaline 💬 Norepinephrine [2] 22, 296 💬
102 Salivary secretion 💬
 [6] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 Pseudoephedrine 💬 Pseudoephedrine [1] 17 💬
103 Vascular smooth muscle contraction 💬
 [1] ADRA1A 💬 Alfuzosin 💬 Alfuzosin [1] 13 💬
104 Vascular smooth muscle contraction 💬
 [1] ADRA1A 💬 Silodosin 💬 Silodosin [2]  6 , 13 💬
105 Vascular smooth muscle contraction 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Amiodarone 💬 Amiodarone [2] 28, 127 💬
106 Vascular smooth muscle contraction 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Carvedilol 💬 Carvedilol [4] 57, 86, 113, 210 💬
107 Vascular smooth muscle contraction 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Dipivefrin 💬 Dipivefrin [1]  6  💬
108 Vascular smooth muscle contraction 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Doxazosin 💬 Doxazosin [2] 57, 67 💬
109 Vascular smooth muscle contraction 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Droxidopa 💬 Droxidopa [5]  5 ,  6 , 17, 169, 170 💬
110 Vascular smooth muscle contraction 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Ephedrine 💬 Ephedrine [1] 11 💬
111 Vascular smooth muscle contraction 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Epinephrine 💬 Epinephrine [3] 46, 70, 96 💬
112 Vascular smooth muscle contraction 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Methylergometrine 💬 Methylergometrine [1] 280 💬
113 Vascular smooth muscle contraction 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Midodrine 💬 Midodrine [3]  6 , 17, 58 💬
114 Vascular smooth muscle contraction 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Noradrenaline 💬 Norepinephrine [2] 22, 296 💬
115 Vascular smooth muscle contraction 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Olanzapine 💬 Olanzapine [2]  2 ,  8  💬
116 Vascular smooth muscle contraction 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Phenylephrine 💬 Phenylephrine [1] 22 💬
117 Vascular smooth muscle contraction 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Pseudoephedrine 💬 Pseudoephedrine [1] 17 💬
118 Vascular smooth muscle contraction 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Tamsulosin 💬 Tamsulosin [1] 13 💬
119 Vascular smooth muscle contraction 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Terazosin 💬 Terazosin [1]  6  💬

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