Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Allograft rejection 💬
 [1] CD40 💬 Bleselumab 💬 Bleselumab [1] 222 💬
2 Allograft rejection 💬
 [1] CD40 💬 Iscalimab 💬 Iscalimab [2] 49, 53 💬
3 Allograft rejection 💬
 [1] CD40 💬 Ravagalimab 💬 Ravagalimab [2] 53, 97 💬
4 Allograft rejection 💬
 [1] CD40LG 💬 Toralizumab 💬 Toralizumab [1] 63 💬
5 Antigen processing and presentation 💬
 [1] CD4 💬 Zanolimumab 💬 Zanolimumab [1] 46 💬
6 Asthma 💬
 [1] CD40 💬 Bleselumab 💬 Bleselumab [1] 222 💬
7 Asthma 💬
 [1] CD40 💬 Iscalimab 💬 Iscalimab [2] 49, 53 💬
8 Asthma 💬
 [1] CD40 💬 Ravagalimab 💬 Ravagalimab [2] 53, 97 💬
9 Asthma 💬
 [1] CD40LG 💬 Toralizumab 💬 Toralizumab [1] 63 💬
10 Autoimmune thyroid disease 💬
 [1] CD40 💬 Bleselumab 💬 Bleselumab [1] 222 💬
11 Autoimmune thyroid disease 💬
 [1] CD40 💬 Iscalimab 💬 Iscalimab [2] 49, 53 💬
12 Autoimmune thyroid disease 💬
 [1] CD40 💬 Ravagalimab 💬 Ravagalimab [2] 53, 97 💬
13 Autoimmune thyroid disease 💬
 [1] CD40LG 💬 Toralizumab 💬 Toralizumab [1] 63 💬
14 Cell adhesion molecules 💬
 [1] CD4 💬 Zanolimumab 💬 Zanolimumab [1] 46 💬
15 Cell adhesion molecules 💬
 [1] CD40 💬 Bleselumab 💬 Bleselumab [1] 222 💬
16 Cell adhesion molecules 💬
 [1] CD40 💬 Iscalimab 💬 Iscalimab [2] 49, 53 💬
17 Cell adhesion molecules 💬
 [1] CD40 💬 Ravagalimab 💬 Ravagalimab [2] 53, 97 💬
18 Cell adhesion molecules 💬
 [1] CD40LG 💬 Toralizumab 💬 Toralizumab [1] 63 💬
19 Cytokine-cytokine receptor interaction 💬
 [1] CD4 💬 Zanolimumab 💬 Zanolimumab [1] 46 💬
20 Cytokine-cytokine receptor interaction 💬
 [1] CD40 💬 Bleselumab 💬 Bleselumab [1] 222 💬
21 Cytokine-cytokine receptor interaction 💬
 [1] CD40 💬 Iscalimab 💬 Iscalimab [2] 49, 53 💬
22 Cytokine-cytokine receptor interaction 💬
 [1] CD40 💬 Ravagalimab 💬 Ravagalimab [2] 53, 97 💬
23 Cytokine-cytokine receptor interaction 💬
 [1] CD40LG 💬 Toralizumab 💬 Toralizumab [1] 63 💬
24 Epstein-Barr virus infection 💬
 [1] CD40 💬 Bleselumab 💬 Bleselumab [1] 222 💬
25 Epstein-Barr virus infection 💬
 [1] CD40 💬 Iscalimab 💬 Iscalimab [2] 49, 53 💬
26 Epstein-Barr virus infection 💬
 [1] CD40 💬 Ravagalimab 💬 Ravagalimab [2] 53, 97 💬
27 Hematopoietic cell lineage 💬
 [1] CD4 💬 Zanolimumab 💬 Zanolimumab [1] 46 💬
28 Human immunodeficiency virus 1 infection 💬
 [1] CD4 💬 Zanolimumab 💬 Zanolimumab [1] 46 💬
29 Human T-cell leukemia virus 1 infection 💬
 [1] CD4 💬 Zanolimumab 💬 Zanolimumab [1] 46 💬
30 Human T-cell leukemia virus 1 infection 💬
 [1] CD40 💬 Bleselumab 💬 Bleselumab [1] 222 💬
31 Human T-cell leukemia virus 1 infection 💬
 [1] CD40 💬 Iscalimab 💬 Iscalimab [2] 49, 53 💬
32 Human T-cell leukemia virus 1 infection 💬
 [1] CD40 💬 Ravagalimab 💬 Ravagalimab [2] 53, 97 💬
33 Intestinal immune network for IgA production 💬
 [1] CD40 💬 Bleselumab 💬 Bleselumab [1] 222 💬
34 Intestinal immune network for IgA production 💬
 [1] CD40 💬 Iscalimab 💬 Iscalimab [2] 49, 53 💬
35 Intestinal immune network for IgA production 💬
 [1] CD40 💬 Ravagalimab 💬 Ravagalimab [2] 53, 97 💬
36 Intestinal immune network for IgA production 💬
 [1] CD40LG 💬 Toralizumab 💬 Toralizumab [1] 63 💬
37 Lipid and atherosclerosis 💬
 [1] CD40 💬 Bleselumab 💬 Bleselumab [1] 222 💬
38 Lipid and atherosclerosis 💬
 [1] CD40 💬 Iscalimab 💬 Iscalimab [2] 49, 53 💬
39 Lipid and atherosclerosis 💬
 [1] CD40 💬 Ravagalimab 💬 Ravagalimab [2] 53, 97 💬
40 Lipid and atherosclerosis 💬
 [1] CD40LG 💬 Toralizumab 💬 Toralizumab [1] 63 💬
41 Malaria 💬
 [1] CD40 💬 Bleselumab 💬 Bleselumab [1] 222 💬
42 Malaria 💬
 [1] CD40 💬 Iscalimab 💬 Iscalimab [2] 49, 53 💬
43 Malaria 💬
 [1] CD40 💬 Ravagalimab 💬 Ravagalimab [2] 53, 97 💬
44 Malaria 💬
 [1] CD40LG 💬 Toralizumab 💬 Toralizumab [1] 63 💬
45 NF-kappa B signaling pathway 💬
 [1] CD40 💬 Bleselumab 💬 Bleselumab [1] 222 💬
46 NF-kappa B signaling pathway 💬
 [1] CD40 💬 Iscalimab 💬 Iscalimab [2] 49, 53 💬
47 NF-kappa B signaling pathway 💬
 [1] CD40 💬 Ravagalimab 💬 Ravagalimab [2] 53, 97 💬
48 NF-kappa B signaling pathway 💬
 [1] CD40LG 💬 Toralizumab 💬 Toralizumab [1] 63 💬
49 PD-L1 expression and PD-1 checkpoint pathway in cancer 💬
 [1] CD4 💬 Zanolimumab 💬 Zanolimumab [1] 46 💬
50 Primary immunodeficiency 💬
 [1] CD4 💬 Zanolimumab 💬 Zanolimumab [1] 46 💬
51 Primary immunodeficiency 💬
 [1] CD40 💬 Bleselumab 💬 Bleselumab [1] 222 💬
52 Primary immunodeficiency 💬
 [1] CD40 💬 Iscalimab 💬 Iscalimab [2] 49, 53 💬
53 Primary immunodeficiency 💬
 [1] CD40 💬 Ravagalimab 💬 Ravagalimab [2] 53, 97 💬
54 Primary immunodeficiency 💬
 [1] CD40LG 💬 Toralizumab 💬 Toralizumab [1] 63 💬
55 Systemic lupus erythematosus 💬
 [1] CD40 💬 Bleselumab 💬 Bleselumab [1] 222 💬
56 Systemic lupus erythematosus 💬
 [1] CD40 💬 Iscalimab 💬 Iscalimab [2] 49, 53 💬
57 Systemic lupus erythematosus 💬
 [1] CD40 💬 Ravagalimab 💬 Ravagalimab [2] 53, 97 💬
58 Systemic lupus erythematosus 💬
 [1] CD40LG 💬 Toralizumab 💬 Toralizumab [1] 63 💬
59 T cell receptor signaling pathway 💬
 [1] CD4 💬 Zanolimumab 💬 Zanolimumab [1] 46 💬
60 T cell receptor signaling pathway 💬
 [1] CD40LG 💬 Toralizumab 💬 Toralizumab [1] 63 💬
61 Th1 and Th2 cell differentiation 💬
 [1] CD4 💬 Zanolimumab 💬 Zanolimumab [1] 46 💬
62 Th17 cell differentiation 💬
 [1] CD4 💬 Zanolimumab 💬 Zanolimumab [1] 46 💬
63 Toll-like receptor signaling pathway 💬
 [1] CD40 💬 Bleselumab 💬 Bleselumab [1] 222 💬
64 Toll-like receptor signaling pathway 💬
 [1] CD40 💬 Iscalimab 💬 Iscalimab [2] 49, 53 💬
65 Toll-like receptor signaling pathway 💬
 [1] CD40 💬 Ravagalimab 💬 Ravagalimab [2] 53, 97 💬
66 Toxoplasmosis 💬
 [1] CD40 💬 Bleselumab 💬 Bleselumab [1] 222 💬
67 Toxoplasmosis 💬
 [1] CD40 💬 Iscalimab 💬 Iscalimab [2] 49, 53 💬
68 Toxoplasmosis 💬
 [1] CD40 💬 Ravagalimab 💬 Ravagalimab [2] 53, 97 💬
69 Toxoplasmosis 💬
 [1] CD40LG 💬 Toralizumab 💬 Toralizumab [1] 63 💬
70 Transcriptional misregulation in cancer 💬
 [1] CD40 💬 Bleselumab 💬 Bleselumab [1] 222 💬
71 Transcriptional misregulation in cancer 💬
 [1] CD40 💬 Iscalimab 💬 Iscalimab [2] 49, 53 💬
72 Transcriptional misregulation in cancer 💬
 [1] CD40 💬 Ravagalimab 💬 Ravagalimab [2] 53, 97 💬
73 Viral life cycle - HIV-1 💬
 [1] CD4 💬 Zanolimumab 💬 Zanolimumab [1] 46 💬
74 Viral myocarditis 💬
 [1] CD40 💬 Bleselumab 💬 Bleselumab [1] 222 💬
75 Viral myocarditis 💬
 [1] CD40 💬 Iscalimab 💬 Iscalimab [2] 49, 53 💬
76 Viral myocarditis 💬
 [1] CD40 💬 Ravagalimab 💬 Ravagalimab [2] 53, 97 💬
77 Viral myocarditis 💬
 [1] CD40LG 💬 Toralizumab 💬 Toralizumab [1] 63 💬
78 Virion - Human immunodeficiency virus 💬
 [1] CD4 💬 Zanolimumab 💬 Zanolimumab [1] 46 💬
79 Yersinia infection 💬
 [1] CD4 💬 Zanolimumab 💬 Zanolimumab [1] 46 💬

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