Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Calcium signaling pathway 💬
 [8] CACNA1C, CACNA1D, CACNA1F, CACNA1S, CHRM1, CHRM2, CHRM3, CHRM5 💬 Propiverine 💬 Propiverine [1] 226 💬
2 Calcium signaling pathway 💬
 [4] CHRM1, CHRM2, CHRM3, CHRM5 💬 Atropine 💬 Atropine [2]  2 , 299 💬
3 Calcium signaling pathway 💬
 [4] CHRM1, CHRM2, CHRM3, CHRM5 💬 Blarcamesine 💬 Blarcamesine [1] 156 💬
4 Calcium signaling pathway 💬
 [4] CHRM1, CHRM2, CHRM3, CHRM5 💬 Oxybutynin 💬 Oxybutynin [3]  6 , 13, 53 💬
5 Calcium signaling pathway 💬
 [4] CHRM1, CHRM2, CHRM3, CHRM5 💬 Scopolamine 💬 Scopolamine [1]  2  💬
6 Calcium signaling pathway 💬
 [4] CHRM1, CHRM2, CHRM3, CHRM5 💬 Trihexyphenidyl 💬 Trihexyphenidyl [2]  5 ,  6  💬
7 Calcium signaling pathway 💬
 [4] CHRM1, CHRM2, CHRM3, CHRM5 💬 Tropicamide 💬 Tropicamide [1]  6  💬
8 Calcium signaling pathway 💬
 [8] CHRM1, CHRM2, CHRM3, CHRM5, HRH1, HTR2A, HTR2B, HTR2C 💬 Chlorpromazine 💬 Chlorpromazine [1] 254 💬
9 Calcium signaling pathway 💬
 [2] CHRM2, CHRM3 💬 Fesoterodine 💬 Fesoterodine [1]  6  💬
10 Calcium signaling pathway 💬
 [2] CHRM2, CHRM3 💬 Pilocarpine 💬 Pilocarpine [3]  6 , 53, 299 💬
11 cAMP signaling pathway 💬
 [6] CACNA1C, CACNA1D, CACNA1F, CACNA1S, CHRM1, CHRM2 💬 Propiverine 💬 Propiverine [1] 226 💬
12 cAMP signaling pathway 💬
 [2] CHRM1, CHRM2 💬 Atropine 💬 Atropine [2]  2 , 299 💬
13 cAMP signaling pathway 💬
 [2] CHRM1, CHRM2 💬 Blarcamesine 💬 Blarcamesine [1] 156 💬
14 cAMP signaling pathway 💬
 [2] CHRM1, CHRM2 💬 Oxybutynin 💬 Oxybutynin [3]  6 , 13, 53 💬
15 cAMP signaling pathway 💬
 [2] CHRM1, CHRM2 💬 Scopolamine 💬 Scopolamine [1]  2  💬
16 cAMP signaling pathway 💬
 [2] CHRM1, CHRM2 💬 Trihexyphenidyl 💬 Trihexyphenidyl [2]  5 ,  6  💬
17 cAMP signaling pathway 💬
 [2] CHRM1, CHRM2 💬 Tropicamide 💬 Tropicamide [1]  6  💬
18 cAMP signaling pathway 💬
 [3] CHRM1, CHRM2, DRD2 💬 Chlorpromazine 💬 Chlorpromazine [1] 254 💬
19 cAMP signaling pathway 💬
 [1] CHRM2 💬 Fesoterodine 💬 Fesoterodine [1]  6  💬
20 cAMP signaling pathway 💬
 [1] CHRM2 💬 Pilocarpine 💬 Pilocarpine [3]  6 , 53, 299 💬
21 Cholinergic synapse 💬
 [9] CACNA1C, CACNA1D, CACNA1F, CACNA1S, CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Propiverine 💬 Propiverine [1] 226 💬
22 Cholinergic synapse 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Atropine 💬 Atropine [2]  2 , 299 💬
23 Cholinergic synapse 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Blarcamesine 💬 Blarcamesine [1] 156 💬
24 Cholinergic synapse 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Chlorpromazine 💬 Chlorpromazine [1] 254 💬
25 Cholinergic synapse 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Oxybutynin 💬 Oxybutynin [3]  6 , 13, 53 💬
26 Cholinergic synapse 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Scopolamine 💬 Scopolamine [1]  2  💬
27 Cholinergic synapse 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Trihexyphenidyl 💬 Trihexyphenidyl [2]  5 ,  6  💬
28 Cholinergic synapse 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Tropicamide 💬 Tropicamide [1]  6  💬
29 Cholinergic synapse 💬
 [2] CHRM2, CHRM3 💬 Fesoterodine 💬 Fesoterodine [1]  6  💬
30 Cholinergic synapse 💬
 [2] CHRM2, CHRM3 💬 Pilocarpine 💬 Pilocarpine [3]  6 , 53, 299 💬
31 Neuroactive ligand-receptor interaction 💬
 [13] ADRA2A, ADRA2B, ADRA2C, CHRM1, CHRM2, CHRM3, CHRM4, CHRM5, DRD2, HRH1, HTR2A, HTR2B, HTR2C 💬 Chlorpromazine 💬 Chlorpromazine [1] 254 💬
32 Neuroactive ligand-receptor interaction 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Atropine 💬 Atropine [2]  2 , 299 💬
33 Neuroactive ligand-receptor interaction 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Blarcamesine 💬 Blarcamesine [1] 156 💬
34 Neuroactive ligand-receptor interaction 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Oxybutynin 💬 Oxybutynin [3]  6 , 13, 53 💬
35 Neuroactive ligand-receptor interaction 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Propiverine 💬 Propiverine [1] 226 💬
36 Neuroactive ligand-receptor interaction 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Scopolamine 💬 Scopolamine [1]  2  💬
37 Neuroactive ligand-receptor interaction 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Trihexyphenidyl 💬 Trihexyphenidyl [2]  5 ,  6  💬
38 Neuroactive ligand-receptor interaction 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Tropicamide 💬 Tropicamide [1]  6  💬
39 Neuroactive ligand-receptor interaction 💬
 [2] CHRM2, CHRM3 💬 Fesoterodine 💬 Fesoterodine [1]  6  💬
40 Neuroactive ligand-receptor interaction 💬
 [2] CHRM2, CHRM3 💬 Pilocarpine 💬 Pilocarpine [3]  6 , 53, 299 💬
41 PI3K-Akt signaling pathway 💬
 [2] CHRM1, CHRM2 💬 Atropine 💬 Atropine [2]  2 , 299 💬
42 PI3K-Akt signaling pathway 💬
 [2] CHRM1, CHRM2 💬 Blarcamesine 💬 Blarcamesine [1] 156 💬
43 PI3K-Akt signaling pathway 💬
 [2] CHRM1, CHRM2 💬 Chlorpromazine 💬 Chlorpromazine [1] 254 💬
44 PI3K-Akt signaling pathway 💬
 [2] CHRM1, CHRM2 💬 Oxybutynin 💬 Oxybutynin [3]  6 , 13, 53 💬
45 PI3K-Akt signaling pathway 💬
 [2] CHRM1, CHRM2 💬 Propiverine 💬 Propiverine [1] 226 💬
46 PI3K-Akt signaling pathway 💬
 [2] CHRM1, CHRM2 💬 Scopolamine 💬 Scopolamine [1]  2  💬
47 PI3K-Akt signaling pathway 💬
 [2] CHRM1, CHRM2 💬 Trihexyphenidyl 💬 Trihexyphenidyl [2]  5 ,  6  💬
48 PI3K-Akt signaling pathway 💬
 [2] CHRM1, CHRM2 💬 Tropicamide 💬 Tropicamide [1]  6  💬
49 PI3K-Akt signaling pathway 💬
 [1] CHRM2 💬 Fesoterodine 💬 Fesoterodine [1]  6  💬
50 PI3K-Akt signaling pathway 💬
 [1] CHRM2 💬 Pilocarpine 💬 Pilocarpine [3]  6 , 53, 299 💬
51 Regulation of actin cytoskeleton 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Atropine 💬 Atropine [2]  2 , 299 💬
52 Regulation of actin cytoskeleton 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Blarcamesine 💬 Blarcamesine [1] 156 💬
53 Regulation of actin cytoskeleton 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Chlorpromazine 💬 Chlorpromazine [1] 254 💬
54 Regulation of actin cytoskeleton 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Oxybutynin 💬 Oxybutynin [3]  6 , 13, 53 💬
55 Regulation of actin cytoskeleton 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Propiverine 💬 Propiverine [1] 226 💬
56 Regulation of actin cytoskeleton 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Scopolamine 💬 Scopolamine [1]  2  💬
57 Regulation of actin cytoskeleton 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Trihexyphenidyl 💬 Trihexyphenidyl [2]  5 ,  6  💬
58 Regulation of actin cytoskeleton 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Tropicamide 💬 Tropicamide [1]  6  💬
59 Regulation of actin cytoskeleton 💬
 [2] CHRM2, CHRM3 💬 Fesoterodine 💬 Fesoterodine [1]  6  💬
60 Regulation of actin cytoskeleton 💬
 [2] CHRM2, CHRM3 💬 Pilocarpine 💬 Pilocarpine [3]  6 , 53, 299 💬

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