Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Acute myeloid leukemia 💬
 [3] CSF1R, FLT3, KIT 💬 Pexidartinib 💬 Pexidartinib [1] 34 💬
2 Acute myeloid leukemia 💬
 [3] CSF1R, FLT3, KIT 💬 Sunitinib 💬 Sunitinib [2] 28, 34 💬
3 Cytokine-cytokine receptor interaction 💬
 [1] CSF1R 💬 Pexidartinib 💬 Pexidartinib [1] 34 💬
4 Cytokine-cytokine receptor interaction 💬
 [1] CSF1R 💬 Sunitinib 💬 Sunitinib [2] 28, 34 💬
5 Hematopoietic cell lineage 💬
 [3] CSF1R, FLT3, KIT 💬 Pexidartinib 💬 Pexidartinib [1] 34 💬
6 Hematopoietic cell lineage 💬
 [3] CSF1R, FLT3, KIT 💬 Sunitinib 💬 Sunitinib [2] 28, 34 💬
7 MAPK signaling pathway 💬
 [8] CSF1R, FLT1, FLT3, FLT4, KDR, KIT, PDGFRA, PDGFRB 💬 Sunitinib 💬 Sunitinib [2] 28, 34 💬
8 MAPK signaling pathway 💬
 [3] CSF1R, FLT3, KIT 💬 Pexidartinib 💬 Pexidartinib [1] 34 💬
9 Osteoclast differentiation 💬
 [1] CSF1R 💬 Pexidartinib 💬 Pexidartinib [1] 34 💬
10 Osteoclast differentiation 💬
 [1] CSF1R 💬 Sunitinib 💬 Sunitinib [2] 28, 34 💬
11 Pathways in cancer 💬
 [7] CSF1R, FLT3, FLT4, KIT, PDGFRA, PDGFRB, RET 💬 Sunitinib 💬 Sunitinib [2] 28, 34 💬
12 Pathways in cancer 💬
 [3] CSF1R, FLT3, KIT 💬 Pexidartinib 💬 Pexidartinib [1] 34 💬
13 PI3K-Akt signaling pathway 💬
 [8] CSF1R, FLT1, FLT3, FLT4, KDR, KIT, PDGFRA, PDGFRB 💬 Sunitinib 💬 Sunitinib [2] 28, 34 💬
14 PI3K-Akt signaling pathway 💬
 [3] CSF1R, FLT3, KIT 💬 Pexidartinib 💬 Pexidartinib [1] 34 💬
15 Rap1 signaling pathway 💬
 [7] CSF1R, FLT1, FLT4, KDR, KIT, PDGFRA, PDGFRB 💬 Sunitinib 💬 Sunitinib [2] 28, 34 💬
16 Rap1 signaling pathway 💬
 [2] CSF1R, KIT 💬 Pexidartinib 💬 Pexidartinib [1] 34 💬
17 Ras signaling pathway 💬
 [8] CSF1R, FLT1, FLT3, FLT4, KDR, KIT, PDGFRA, PDGFRB 💬 Sunitinib 💬 Sunitinib [2] 28, 34 💬
18 Ras signaling pathway 💬
 [3] CSF1R, FLT3, KIT 💬 Pexidartinib 💬 Pexidartinib [1] 34 💬
19 Transcriptional misregulation in cancer 💬
 [3] CSF1R, FLT1, FLT3 💬 Sunitinib 💬 Sunitinib [2] 28, 34 💬
20 Transcriptional misregulation in cancer 💬
 [2] CSF1R, FLT3 💬 Pexidartinib 💬 Pexidartinib [1] 34 💬
21 Viral protein interaction with cytokine and cytokine receptor 💬
 [1] CSF1R 💬 Pexidartinib 💬 Pexidartinib [1] 34 💬
22 Viral protein interaction with cytokine and cytokine receptor 💬
 [1] CSF1R 💬 Sunitinib 💬 Sunitinib [2] 28, 34 💬

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