Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Calcium signaling pathway 💬
 [8] FGFR1, FGFR2, FGFR3, FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬 Nintedanib 💬 Nintedanib [5] 51, 85, 89, 227, 228 💬
2 Calcium signaling pathway 💬
 [3] FLT1, FLT4, KDR 💬 Axitinib 💬 Axitinib [1] 34 💬
3 Calcium signaling pathway 💬
 [3] FLT1, FLT4, KDR 💬 Cediranib 💬 Cediranib [1] 34 💬
4 Calcium signaling pathway 💬
 [6] FLT1, FLT4, KDR, PDGFRA, PDGFRB, RET 💬 Sunitinib 💬 Sunitinib [2] 28, 34 💬
5 Focal adhesion 💬
 [3] FLT1, FLT4, KDR 💬 Axitinib 💬 Axitinib [1] 34 💬
6 Focal adhesion 💬
 [3] FLT1, FLT4, KDR 💬 Cediranib 💬 Cediranib [1] 34 💬
7 Focal adhesion 💬
 [5] FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬 Nintedanib 💬 Nintedanib [5] 51, 85, 89, 227, 228 💬
8 Focal adhesion 💬
 [5] FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬 Sunitinib 💬 Sunitinib [2] 28, 34 💬
9 HIF-1 signaling pathway 💬
 [1] FLT1 💬 Axitinib 💬 Axitinib [1] 34 💬
10 HIF-1 signaling pathway 💬
 [1] FLT1 💬 Cediranib 💬 Cediranib [1] 34 💬
11 HIF-1 signaling pathway 💬
 [1] FLT1 💬 Nintedanib 💬 Nintedanib [5] 51, 85, 89, 227, 228 💬
12 HIF-1 signaling pathway 💬
 [1] FLT1 💬 Sunitinib 💬 Sunitinib [2] 28, 34 💬
13 MAPK signaling pathway 💬
 [8] CSF1R, FLT1, FLT3, FLT4, KDR, KIT, PDGFRA, PDGFRB 💬 Sunitinib 💬 Sunitinib [2] 28, 34 💬
14 MAPK signaling pathway 💬
 [8] FGFR1, FGFR2, FGFR3, FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬 Nintedanib 💬 Nintedanib [5] 51, 85, 89, 227, 228 💬
15 MAPK signaling pathway 💬
 [3] FLT1, FLT4, KDR 💬 Axitinib 💬 Axitinib [1] 34 💬
16 MAPK signaling pathway 💬
 [3] FLT1, FLT4, KDR 💬 Cediranib 💬 Cediranib [1] 34 💬
17 PI3K-Akt signaling pathway 💬
 [8] CSF1R, FLT1, FLT3, FLT4, KDR, KIT, PDGFRA, PDGFRB 💬 Sunitinib 💬 Sunitinib [2] 28, 34 💬
18 PI3K-Akt signaling pathway 💬
 [8] FGFR1, FGFR2, FGFR3, FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬 Nintedanib 💬 Nintedanib [5] 51, 85, 89, 227, 228 💬
19 PI3K-Akt signaling pathway 💬
 [3] FLT1, FLT4, KDR 💬 Axitinib 💬 Axitinib [1] 34 💬
20 PI3K-Akt signaling pathway 💬
 [3] FLT1, FLT4, KDR 💬 Cediranib 💬 Cediranib [1] 34 💬
21 Rap1 signaling pathway 💬
 [7] CSF1R, FLT1, FLT4, KDR, KIT, PDGFRA, PDGFRB 💬 Sunitinib 💬 Sunitinib [2] 28, 34 💬
22 Rap1 signaling pathway 💬
 [8] FGFR1, FGFR2, FGFR3, FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬 Nintedanib 💬 Nintedanib [5] 51, 85, 89, 227, 228 💬
23 Rap1 signaling pathway 💬
 [3] FLT1, FLT4, KDR 💬 Axitinib 💬 Axitinib [1] 34 💬
24 Rap1 signaling pathway 💬
 [3] FLT1, FLT4, KDR 💬 Cediranib 💬 Cediranib [1] 34 💬
25 Ras signaling pathway 💬
 [8] CSF1R, FLT1, FLT3, FLT4, KDR, KIT, PDGFRA, PDGFRB 💬 Sunitinib 💬 Sunitinib [2] 28, 34 💬
26 Ras signaling pathway 💬
 [8] FGFR1, FGFR2, FGFR3, FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬 Nintedanib 💬 Nintedanib [5] 51, 85, 89, 227, 228 💬
27 Ras signaling pathway 💬
 [3] FLT1, FLT4, KDR 💬 Axitinib 💬 Axitinib [1] 34 💬
28 Ras signaling pathway 💬
 [3] FLT1, FLT4, KDR 💬 Cediranib 💬 Cediranib [1] 34 💬
29 Rheumatoid arthritis 💬
 [1] FLT1 💬 Axitinib 💬 Axitinib [1] 34 💬
30 Rheumatoid arthritis 💬
 [1] FLT1 💬 Cediranib 💬 Cediranib [1] 34 💬
31 Rheumatoid arthritis 💬
 [1] FLT1 💬 Nintedanib 💬 Nintedanib [5] 51, 85, 89, 227, 228 💬
32 Rheumatoid arthritis 💬
 [1] FLT1 💬 Sunitinib 💬 Sunitinib [2] 28, 34 💬
33 Transcriptional misregulation in cancer 💬
 [3] CSF1R, FLT1, FLT3 💬 Sunitinib 💬 Sunitinib [2] 28, 34 💬
34 Transcriptional misregulation in cancer 💬
 [1] FLT1 💬 Axitinib 💬 Axitinib [1] 34 💬
35 Transcriptional misregulation in cancer 💬
 [1] FLT1 💬 Cediranib 💬 Cediranib [1] 34 💬
36 Transcriptional misregulation in cancer 💬
 [1] FLT1 💬 Nintedanib 💬 Nintedanib [5] 51, 85, 89, 227, 228 💬

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