Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Calcium signaling pathway 💬
 [8] ADRA1A, ADRA1B, ADRA1D, HRH1, HTR2A, HTR2B, HTR2C, HTR6 💬 Olanzapine 💬 Olanzapine [2]  2 ,  8  💬
2 Calcium signaling pathway 💬
 [8] CHRM1, CHRM2, CHRM3, CHRM5, HRH1, HTR2A, HTR2B, HTR2C 💬 Chlorpromazine 💬 Chlorpromazine [1] 254 💬
3 Calcium signaling pathway 💬
 [1] HRH1 💬 Cetirizine 💬 Cetirizine [4] 13, 28, 35, 300 💬
4 Calcium signaling pathway 💬
 [1] HRH1 💬 Chlorphenamine 💬 Chlorpheniramine [1] 14 💬
5 Calcium signaling pathway 💬
 [1] HRH1 💬 Clemastine 💬 Clemastine [1] 13 💬
6 Calcium signaling pathway 💬
 [1] HRH1 💬 Desloratadine 💬 Desloratadine [1] 13 💬
7 Calcium signaling pathway 💬
 [1] HRH1 💬 Dexchlorpheniramine 💬 Dexchlorpheniramine [2] 13, 49 💬
8 Calcium signaling pathway 💬
 [1] HRH1 💬 Diphenhydramine 💬 Diphenhydramine [8] 11, 13, 49, 51, 70, 86, 222, 256 💬
9 Calcium signaling pathway 💬
 [1] HRH1 💬 Doxepin 💬 Doxepin [1]  6  💬
10 Calcium signaling pathway 💬
 [1] HRH1 💬 Fexofenadine 💬 Fexofenadine [2] 13, 46 💬
11 Calcium signaling pathway 💬
 [1] HRH1 💬 Levocetirizine 💬 Levocetirizine [1] 61 💬
12 Calcium signaling pathway 💬
 [1] HRH1 💬 Loratadine 💬 Loratadine [4] 13, 46, 89, 98 💬
13 Calcium signaling pathway 💬
 [1] HRH1 💬 Promethazine 💬 Promethazine [1] 96 💬
14 Calcium signaling pathway 💬
 [2] HRH1, PTAFR 💬 Rupatadine 💬 Rupatadine [1] 46 💬
15 Inflammatory mediator regulation of TRP channels 💬
 [1] HRH1 💬 Cetirizine 💬 Cetirizine [4] 13, 28, 35, 300 💬
16 Inflammatory mediator regulation of TRP channels 💬
 [1] HRH1 💬 Chlorphenamine 💬 Chlorpheniramine [1] 14 💬
17 Inflammatory mediator regulation of TRP channels 💬
 [1] HRH1 💬 Clemastine 💬 Clemastine [1] 13 💬
18 Inflammatory mediator regulation of TRP channels 💬
 [1] HRH1 💬 Desloratadine 💬 Desloratadine [1] 13 💬
19 Inflammatory mediator regulation of TRP channels 💬
 [1] HRH1 💬 Dexchlorpheniramine 💬 Dexchlorpheniramine [2] 13, 49 💬
20 Inflammatory mediator regulation of TRP channels 💬
 [1] HRH1 💬 Diphenhydramine 💬 Diphenhydramine [8] 11, 13, 49, 51, 70, 86, 222, 256 💬
21 Inflammatory mediator regulation of TRP channels 💬
 [1] HRH1 💬 Doxepin 💬 Doxepin [1]  6  💬
22 Inflammatory mediator regulation of TRP channels 💬
 [1] HRH1 💬 Fexofenadine 💬 Fexofenadine [2] 13, 46 💬
23 Inflammatory mediator regulation of TRP channels 💬
 [1] HRH1 💬 Levocetirizine 💬 Levocetirizine [1] 61 💬
24 Inflammatory mediator regulation of TRP channels 💬
 [1] HRH1 💬 Loratadine 💬 Loratadine [4] 13, 46, 89, 98 💬
25 Inflammatory mediator regulation of TRP channels 💬
 [1] HRH1 💬 Promethazine 💬 Promethazine [1] 96 💬
26 Inflammatory mediator regulation of TRP channels 💬
 [1] HRH1 💬 Rupatadine 💬 Rupatadine [1] 46 💬
27 Inflammatory mediator regulation of TRP channels 💬
 [4] HRH1, HTR2A, HTR2B, HTR2C 💬 Chlorpromazine 💬 Chlorpromazine [1] 254 💬
28 Inflammatory mediator regulation of TRP channels 💬
 [4] HRH1, HTR2A, HTR2B, HTR2C 💬 Olanzapine 💬 Olanzapine [2]  2 ,  8  💬
29 Neuroactive ligand-receptor interaction 💬
 [11] ADRA1A, ADRA1B, ADRA1D, DRD2, DRD3, DRD4, HRH1, HTR2A, HTR2B, HTR2C, HTR6 💬 Olanzapine 💬 Olanzapine [2]  2 ,  8  💬
30 Neuroactive ligand-receptor interaction 💬
 [13] ADRA2A, ADRA2B, ADRA2C, CHRM1, CHRM2, CHRM3, CHRM4, CHRM5, DRD2, HRH1, HTR2A, HTR2B, HTR2C 💬 Chlorpromazine 💬 Chlorpromazine [1] 254 💬
31 Neuroactive ligand-receptor interaction 💬
 [1] HRH1 💬 Cetirizine 💬 Cetirizine [4] 13, 28, 35, 300 💬
32 Neuroactive ligand-receptor interaction 💬
 [1] HRH1 💬 Chlorphenamine 💬 Chlorpheniramine [1] 14 💬
33 Neuroactive ligand-receptor interaction 💬
 [1] HRH1 💬 Clemastine 💬 Clemastine [1] 13 💬
34 Neuroactive ligand-receptor interaction 💬
 [1] HRH1 💬 Desloratadine 💬 Desloratadine [1] 13 💬
35 Neuroactive ligand-receptor interaction 💬
 [1] HRH1 💬 Dexchlorpheniramine 💬 Dexchlorpheniramine [2] 13, 49 💬
36 Neuroactive ligand-receptor interaction 💬
 [1] HRH1 💬 Diphenhydramine 💬 Diphenhydramine [8] 11, 13, 49, 51, 70, 86, 222, 256 💬
37 Neuroactive ligand-receptor interaction 💬
 [1] HRH1 💬 Doxepin 💬 Doxepin [1]  6  💬
38 Neuroactive ligand-receptor interaction 💬
 [1] HRH1 💬 Fexofenadine 💬 Fexofenadine [2] 13, 46 💬
39 Neuroactive ligand-receptor interaction 💬
 [1] HRH1 💬 Levocetirizine 💬 Levocetirizine [1] 61 💬
40 Neuroactive ligand-receptor interaction 💬
 [1] HRH1 💬 Loratadine 💬 Loratadine [4] 13, 46, 89, 98 💬
41 Neuroactive ligand-receptor interaction 💬
 [1] HRH1 💬 Promethazine 💬 Promethazine [1] 96 💬
42 Neuroactive ligand-receptor interaction 💬
 [2] HRH1, PTAFR 💬 Rupatadine 💬 Rupatadine [1] 46 💬

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