Gene

Search results

No.

KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related

C-type lectin receptor signaling pathway 💬

[3] IL12A, IL12B, IL23A 💬

Ustekinumab 💬

Ustekinumab

[16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬

Disease ID	Name
37	Generalised pustular psoriasis;Pustular psoriasis;
40	Takayasu arteritis;Aortitis syndrome;Pulseless disease;Aortitis syndrome;
41	Giant cell arteritis;Temporal arteritis;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
49	Systemic lupus erythematosus;SLE;
50	Dermatomyositis;Polymyositis;
56	Behcet disease;Behçet disease;BD;
65	Primary immunodeficiency;
84	Sarcoidosis;
93	Primary biliary cholangitis;Primary biliary cirrhosis;PBC;
96	Crohn disease;Terminal ileitis;
97	Ulcerative colitis;
160	Congenital ichthyosis;
162	Pemphigoid;
269	Pyogenic arthritis;Pyoderma gangrenosum;Acne syndrome;PAPA syndrome;
271	Ankylosing spondylitis;Spondylarthritis ankylopoietica;

C-type lectin receptor signaling pathway 💬

[1] IL23A 💬

Brazikumab 💬

Brazikumab

[2] 96, 97 💬

C-type lectin receptor signaling pathway 💬

[1] IL23A 💬

Guselkumab 💬

Guselkumab

[5] 37, 41, 51, 96, 97 💬

Disease ID	Name
37	Generalised pustular psoriasis;Pustular psoriasis;
41	Giant cell arteritis;Temporal arteritis;
51	Scleroderma;Systemic sclerosis;SSc;
96	Crohn disease;Terminal ileitis;
97	Ulcerative colitis;

C-type lectin receptor signaling pathway 💬

[1] IL23A 💬

Mirikizumab 💬

Mirikizumab

[3] 37, 96, 97 💬

C-type lectin receptor signaling pathway 💬

[1] IL23A 💬

Risankizumab 💬

Risankizumab

[4] 37, 96, 97, 271 💬

C-type lectin receptor signaling pathway 💬

[1] IL23A 💬

Tildrakizumab 💬

Tildrakizumab

[2] 162, 271 💬

Cytokine-cytokine receptor interaction 💬

[3] IL12A, IL12B, IL23A 💬

Ustekinumab 💬

Ustekinumab

[16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬

Disease ID	Name
37	Generalised pustular psoriasis;Pustular psoriasis;
40	Takayasu arteritis;Aortitis syndrome;Pulseless disease;Aortitis syndrome;
41	Giant cell arteritis;Temporal arteritis;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
49	Systemic lupus erythematosus;SLE;
50	Dermatomyositis;Polymyositis;
56	Behcet disease;Behçet disease;BD;
65	Primary immunodeficiency;
84	Sarcoidosis;
93	Primary biliary cholangitis;Primary biliary cirrhosis;PBC;
96	Crohn disease;Terminal ileitis;
97	Ulcerative colitis;
160	Congenital ichthyosis;
162	Pemphigoid;
269	Pyogenic arthritis;Pyoderma gangrenosum;Acne syndrome;PAPA syndrome;
271	Ankylosing spondylitis;Spondylarthritis ankylopoietica;

Cytokine-cytokine receptor interaction 💬

[1] IL23A 💬

Brazikumab 💬

Brazikumab

[2] 96, 97 💬

Cytokine-cytokine receptor interaction 💬

[1] IL23A 💬

Guselkumab 💬

Guselkumab

[5] 37, 41, 51, 96, 97 💬

Disease ID	Name
37	Generalised pustular psoriasis;Pustular psoriasis;
41	Giant cell arteritis;Temporal arteritis;
51	Scleroderma;Systemic sclerosis;SSc;
96	Crohn disease;Terminal ileitis;
97	Ulcerative colitis;

Cytokine-cytokine receptor interaction 💬

[1] IL23A 💬

Mirikizumab 💬

Mirikizumab

[3] 37, 96, 97 💬

Cytokine-cytokine receptor interaction 💬

[1] IL23A 💬

Risankizumab 💬

Risankizumab

[4] 37, 96, 97, 271 💬

Cytokine-cytokine receptor interaction 💬

[1] IL23A 💬

Tildrakizumab 💬

Tildrakizumab

[2] 162, 271 💬

Inflammatory bowel disease 💬

[3] IL12A, IL12B, IL23A 💬

Ustekinumab 💬

Ustekinumab

[16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬

Disease ID	Name
37	Generalised pustular psoriasis;Pustular psoriasis;
40	Takayasu arteritis;Aortitis syndrome;Pulseless disease;Aortitis syndrome;
41	Giant cell arteritis;Temporal arteritis;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
49	Systemic lupus erythematosus;SLE;
50	Dermatomyositis;Polymyositis;
56	Behcet disease;Behçet disease;BD;
65	Primary immunodeficiency;
84	Sarcoidosis;
93	Primary biliary cholangitis;Primary biliary cirrhosis;PBC;
96	Crohn disease;Terminal ileitis;
97	Ulcerative colitis;
160	Congenital ichthyosis;
162	Pemphigoid;
269	Pyogenic arthritis;Pyoderma gangrenosum;Acne syndrome;PAPA syndrome;
271	Ankylosing spondylitis;Spondylarthritis ankylopoietica;

Inflammatory bowel disease 💬

[1] IL23A 💬

Brazikumab 💬

Brazikumab

[2] 96, 97 💬

Inflammatory bowel disease 💬

[1] IL23A 💬

Guselkumab 💬

Guselkumab

[5] 37, 41, 51, 96, 97 💬

Disease ID	Name
37	Generalised pustular psoriasis;Pustular psoriasis;
41	Giant cell arteritis;Temporal arteritis;
51	Scleroderma;Systemic sclerosis;SSc;
96	Crohn disease;Terminal ileitis;
97	Ulcerative colitis;

Inflammatory bowel disease 💬

[1] IL23A 💬

Mirikizumab 💬

Mirikizumab

[3] 37, 96, 97 💬

Inflammatory bowel disease 💬

[1] IL23A 💬

Risankizumab 💬

Risankizumab

[4] 37, 96, 97, 271 💬

Inflammatory bowel disease 💬

[1] IL23A 💬

Tildrakizumab 💬

Tildrakizumab

[2] 162, 271 💬

JAK-STAT signaling pathway 💬

[3] IL12A, IL12B, IL23A 💬

Ustekinumab 💬

Ustekinumab

[16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬

Disease ID	Name
37	Generalised pustular psoriasis;Pustular psoriasis;
40	Takayasu arteritis;Aortitis syndrome;Pulseless disease;Aortitis syndrome;
41	Giant cell arteritis;Temporal arteritis;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
49	Systemic lupus erythematosus;SLE;
50	Dermatomyositis;Polymyositis;
56	Behcet disease;Behçet disease;BD;
65	Primary immunodeficiency;
84	Sarcoidosis;
93	Primary biliary cholangitis;Primary biliary cirrhosis;PBC;
96	Crohn disease;Terminal ileitis;
97	Ulcerative colitis;
160	Congenital ichthyosis;
162	Pemphigoid;
269	Pyogenic arthritis;Pyoderma gangrenosum;Acne syndrome;PAPA syndrome;
271	Ankylosing spondylitis;Spondylarthritis ankylopoietica;

JAK-STAT signaling pathway 💬

[1] IL23A 💬

Brazikumab 💬

Brazikumab

[2] 96, 97 💬

JAK-STAT signaling pathway 💬

[1] IL23A 💬

Guselkumab 💬

Guselkumab

[5] 37, 41, 51, 96, 97 💬

Disease ID	Name
37	Generalised pustular psoriasis;Pustular psoriasis;
41	Giant cell arteritis;Temporal arteritis;
51	Scleroderma;Systemic sclerosis;SSc;
96	Crohn disease;Terminal ileitis;
97	Ulcerative colitis;

JAK-STAT signaling pathway 💬

[1] IL23A 💬

Mirikizumab 💬

Mirikizumab

[3] 37, 96, 97 💬

JAK-STAT signaling pathway 💬

[1] IL23A 💬

Risankizumab 💬

Risankizumab

[4] 37, 96, 97, 271 💬

JAK-STAT signaling pathway 💬

[1] IL23A 💬

Tildrakizumab 💬

Tildrakizumab

[2] 162, 271 💬

Pathways in cancer 💬

[3] IL12A, IL12B, IL23A 💬

Ustekinumab 💬

Ustekinumab

[16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬

Disease ID	Name
37	Generalised pustular psoriasis;Pustular psoriasis;
40	Takayasu arteritis;Aortitis syndrome;Pulseless disease;Aortitis syndrome;
41	Giant cell arteritis;Temporal arteritis;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
49	Systemic lupus erythematosus;SLE;
50	Dermatomyositis;Polymyositis;
56	Behcet disease;Behçet disease;BD;
65	Primary immunodeficiency;
84	Sarcoidosis;
93	Primary biliary cholangitis;Primary biliary cirrhosis;PBC;
96	Crohn disease;Terminal ileitis;
97	Ulcerative colitis;
160	Congenital ichthyosis;
162	Pemphigoid;
269	Pyogenic arthritis;Pyoderma gangrenosum;Acne syndrome;PAPA syndrome;
271	Ankylosing spondylitis;Spondylarthritis ankylopoietica;

Pathways in cancer 💬

[1] IL23A 💬

Brazikumab 💬

Brazikumab

[2] 96, 97 💬

Pathways in cancer 💬

[1] IL23A 💬

Guselkumab 💬

Guselkumab

[5] 37, 41, 51, 96, 97 💬

Disease ID	Name
37	Generalised pustular psoriasis;Pustular psoriasis;
41	Giant cell arteritis;Temporal arteritis;
51	Scleroderma;Systemic sclerosis;SSc;
96	Crohn disease;Terminal ileitis;
97	Ulcerative colitis;

Pathways in cancer 💬

[1] IL23A 💬

Mirikizumab 💬

Mirikizumab

[3] 37, 96, 97 💬

Pathways in cancer 💬

[1] IL23A 💬

Risankizumab 💬

Risankizumab

[4] 37, 96, 97, 271 💬

Pathways in cancer 💬

[1] IL23A 💬

Tildrakizumab 💬

Tildrakizumab

[2] 162, 271 💬

Pertussis 💬

[3] IL12A, IL12B, IL23A 💬

Ustekinumab 💬

Ustekinumab

[16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬

Disease ID	Name
37	Generalised pustular psoriasis;Pustular psoriasis;
40	Takayasu arteritis;Aortitis syndrome;Pulseless disease;Aortitis syndrome;
41	Giant cell arteritis;Temporal arteritis;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
49	Systemic lupus erythematosus;SLE;
50	Dermatomyositis;Polymyositis;
56	Behcet disease;Behçet disease;BD;
65	Primary immunodeficiency;
84	Sarcoidosis;
93	Primary biliary cholangitis;Primary biliary cirrhosis;PBC;
96	Crohn disease;Terminal ileitis;
97	Ulcerative colitis;
160	Congenital ichthyosis;
162	Pemphigoid;
269	Pyogenic arthritis;Pyoderma gangrenosum;Acne syndrome;PAPA syndrome;
271	Ankylosing spondylitis;Spondylarthritis ankylopoietica;

Pertussis 💬

[1] IL23A 💬

Brazikumab 💬

Brazikumab

[2] 96, 97 💬

Pertussis 💬

[1] IL23A 💬

Guselkumab 💬

Guselkumab

[5] 37, 41, 51, 96, 97 💬

Disease ID	Name
37	Generalised pustular psoriasis;Pustular psoriasis;
41	Giant cell arteritis;Temporal arteritis;
51	Scleroderma;Systemic sclerosis;SSc;
96	Crohn disease;Terminal ileitis;
97	Ulcerative colitis;

Pertussis 💬

[1] IL23A 💬

Mirikizumab 💬

Mirikizumab

[3] 37, 96, 97 💬

Pertussis 💬

[1] IL23A 💬

Risankizumab 💬

Risankizumab

[4] 37, 96, 97, 271 💬

Pertussis 💬

[1] IL23A 💬

Tildrakizumab 💬

Tildrakizumab

[2] 162, 271 💬

Rheumatoid arthritis 💬

[1] IL23A 💬

Brazikumab 💬

Brazikumab

[2] 96, 97 💬

Rheumatoid arthritis 💬

[1] IL23A 💬

Guselkumab 💬

Guselkumab

[5] 37, 41, 51, 96, 97 💬

Disease ID	Name
37	Generalised pustular psoriasis;Pustular psoriasis;
41	Giant cell arteritis;Temporal arteritis;
51	Scleroderma;Systemic sclerosis;SSc;
96	Crohn disease;Terminal ileitis;
97	Ulcerative colitis;

Rheumatoid arthritis 💬

[1] IL23A 💬

Mirikizumab 💬

Mirikizumab

[3] 37, 96, 97 💬

Rheumatoid arthritis 💬

[1] IL23A 💬

Risankizumab 💬

Risankizumab

[4] 37, 96, 97, 271 💬

Rheumatoid arthritis 💬

[1] IL23A 💬

Tildrakizumab 💬

Tildrakizumab

[2] 162, 271 💬

Rheumatoid arthritis 💬

[1] IL23A 💬

Ustekinumab 💬

Ustekinumab

[16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬

Disease ID	Name
37	Generalised pustular psoriasis;Pustular psoriasis;
40	Takayasu arteritis;Aortitis syndrome;Pulseless disease;Aortitis syndrome;
41	Giant cell arteritis;Temporal arteritis;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
49	Systemic lupus erythematosus;SLE;
50	Dermatomyositis;Polymyositis;
56	Behcet disease;Behçet disease;BD;
65	Primary immunodeficiency;
84	Sarcoidosis;
93	Primary biliary cholangitis;Primary biliary cirrhosis;PBC;
96	Crohn disease;Terminal ileitis;
97	Ulcerative colitis;
160	Congenital ichthyosis;
162	Pemphigoid;
269	Pyogenic arthritis;Pyoderma gangrenosum;Acne syndrome;PAPA syndrome;
271	Ankylosing spondylitis;Spondylarthritis ankylopoietica;

Th17 cell differentiation 💬

[1] IL23A 💬

Brazikumab 💬

Brazikumab

[2] 96, 97 💬

Th17 cell differentiation 💬

[1] IL23A 💬

Guselkumab 💬

Guselkumab

[5] 37, 41, 51, 96, 97 💬

Disease ID	Name
37	Generalised pustular psoriasis;Pustular psoriasis;
41	Giant cell arteritis;Temporal arteritis;
51	Scleroderma;Systemic sclerosis;SSc;
96	Crohn disease;Terminal ileitis;
97	Ulcerative colitis;

Th17 cell differentiation 💬

[1] IL23A 💬

Mirikizumab 💬

Mirikizumab

[3] 37, 96, 97 💬

Th17 cell differentiation 💬

[1] IL23A 💬

Risankizumab 💬

Risankizumab

[4] 37, 96, 97, 271 💬

Th17 cell differentiation 💬

[1] IL23A 💬

Tildrakizumab 💬

Tildrakizumab

[2] 162, 271 💬

Th17 cell differentiation 💬

[1] IL23A 💬

Ustekinumab 💬

Ustekinumab

[16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬

Disease ID	Name
37	Generalised pustular psoriasis;Pustular psoriasis;
40	Takayasu arteritis;Aortitis syndrome;Pulseless disease;Aortitis syndrome;
41	Giant cell arteritis;Temporal arteritis;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
49	Systemic lupus erythematosus;SLE;
50	Dermatomyositis;Polymyositis;
56	Behcet disease;Behçet disease;BD;
65	Primary immunodeficiency;
84	Sarcoidosis;
93	Primary biliary cholangitis;Primary biliary cirrhosis;PBC;
96	Crohn disease;Terminal ileitis;
97	Ulcerative colitis;
160	Congenital ichthyosis;
162	Pemphigoid;
269	Pyogenic arthritis;Pyoderma gangrenosum;Acne syndrome;PAPA syndrome;
271	Ankylosing spondylitis;Spondylarthritis ankylopoietica;

Tuberculosis 💬

[3] IL12A, IL12B, IL23A 💬

Ustekinumab 💬

Ustekinumab

[16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬

Disease ID	Name
37	Generalised pustular psoriasis;Pustular psoriasis;
40	Takayasu arteritis;Aortitis syndrome;Pulseless disease;Aortitis syndrome;
41	Giant cell arteritis;Temporal arteritis;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
49	Systemic lupus erythematosus;SLE;
50	Dermatomyositis;Polymyositis;
56	Behcet disease;Behçet disease;BD;
65	Primary immunodeficiency;
84	Sarcoidosis;
93	Primary biliary cholangitis;Primary biliary cirrhosis;PBC;
96	Crohn disease;Terminal ileitis;
97	Ulcerative colitis;
160	Congenital ichthyosis;
162	Pemphigoid;
269	Pyogenic arthritis;Pyoderma gangrenosum;Acne syndrome;PAPA syndrome;
271	Ankylosing spondylitis;Spondylarthritis ankylopoietica;

Tuberculosis 💬

[1] IL23A 💬

Brazikumab 💬

Brazikumab

[2] 96, 97 💬

Tuberculosis 💬

[1] IL23A 💬

Guselkumab 💬

Guselkumab

[5] 37, 41, 51, 96, 97 💬

Disease ID	Name
37	Generalised pustular psoriasis;Pustular psoriasis;
41	Giant cell arteritis;Temporal arteritis;
51	Scleroderma;Systemic sclerosis;SSc;
96	Crohn disease;Terminal ileitis;
97	Ulcerative colitis;

Tuberculosis 💬

[1] IL23A 💬

Mirikizumab 💬

Mirikizumab

[3] 37, 96, 97 💬

Tuberculosis 💬

[1] IL23A 💬

Risankizumab 💬

Risankizumab

[4] 37, 96, 97, 271 💬

Tuberculosis 💬

[1] IL23A 💬

Tildrakizumab 💬

Tildrakizumab

[2] 162, 271 💬