Gene

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No.

KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related

Cytokine-cytokine receptor interaction 💬

[1] IL2RA 💬

Basiliximab 💬

Basiliximab

[6] 2 , 50, 66, 97, 222, 228 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
50	Dermatomyositis;Polymyositis;
66	IgA nephropathy;IgA nephritis;Berger disease;IgA-IgG nephropathy;
97	Ulcerative colitis;
222	Primary nephrotic syndrome;
228	Bronchiolitis obliterans;Obliterating bronchiolitis;

Cytokine-cytokine receptor interaction 💬

[1] IL2RA 💬

Daclizumab 💬

Daclizumab

[8] 13, 56, 60, 65, 97, 107, 283, 284 💬

Disease ID	Name
13	Multiple sclerosis/Neuromyelitis optica;
56	Behcet disease;Behçet disease;BD;
60	Aplastic anemia;
65	Primary immunodeficiency;
97	Ulcerative colitis;
107	Juvenile idiopathic arthritis;JIA;
283	Acquired pure red cell aplasia;Pure red cell aplasia;
284	Diamond-Blackfan anemia;

Cytokine-cytokine receptor interaction 💬

[3] IL2RA, IL2RB, IL2RG 💬

Aldesleukin 💬

Aldesleukin

[6] 2 , 35, 49, 65, 96, 97 💬

Endocytosis 💬

[1] IL2RA 💬

Basiliximab 💬

Basiliximab

[6] 2 , 50, 66, 97, 222, 228 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
50	Dermatomyositis;Polymyositis;
66	IgA nephropathy;IgA nephritis;Berger disease;IgA-IgG nephropathy;
97	Ulcerative colitis;
222	Primary nephrotic syndrome;
228	Bronchiolitis obliterans;Obliterating bronchiolitis;

Endocytosis 💬

[1] IL2RA 💬

Daclizumab 💬

Daclizumab

[8] 13, 56, 60, 65, 97, 107, 283, 284 💬

Disease ID	Name
13	Multiple sclerosis/Neuromyelitis optica;
56	Behcet disease;Behçet disease;BD;
60	Aplastic anemia;
65	Primary immunodeficiency;
97	Ulcerative colitis;
107	Juvenile idiopathic arthritis;JIA;
283	Acquired pure red cell aplasia;Pure red cell aplasia;
284	Diamond-Blackfan anemia;

Endocytosis 💬

[3] IL2RA, IL2RB, IL2RG 💬

Aldesleukin 💬

Aldesleukin

[6] 2 , 35, 49, 65, 96, 97 💬

Hematopoietic cell lineage 💬

[1] IL2RA 💬

Aldesleukin 💬

Aldesleukin

[6] 2 , 35, 49, 65, 96, 97 💬

Hematopoietic cell lineage 💬

[1] IL2RA 💬

Basiliximab 💬

Basiliximab

[6] 2 , 50, 66, 97, 222, 228 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
50	Dermatomyositis;Polymyositis;
66	IgA nephropathy;IgA nephritis;Berger disease;IgA-IgG nephropathy;
97	Ulcerative colitis;
222	Primary nephrotic syndrome;
228	Bronchiolitis obliterans;Obliterating bronchiolitis;

Hematopoietic cell lineage 💬

[1] IL2RA 💬

Daclizumab 💬

Daclizumab

[8] 13, 56, 60, 65, 97, 107, 283, 284 💬

Disease ID	Name
13	Multiple sclerosis/Neuromyelitis optica;
56	Behcet disease;Behçet disease;BD;
60	Aplastic anemia;
65	Primary immunodeficiency;
97	Ulcerative colitis;
107	Juvenile idiopathic arthritis;JIA;
283	Acquired pure red cell aplasia;Pure red cell aplasia;
284	Diamond-Blackfan anemia;

Human T-cell leukemia virus 1 infection 💬

[1] IL2RA 💬

Basiliximab 💬

Basiliximab

[6] 2 , 50, 66, 97, 222, 228 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
50	Dermatomyositis;Polymyositis;
66	IgA nephropathy;IgA nephritis;Berger disease;IgA-IgG nephropathy;
97	Ulcerative colitis;
222	Primary nephrotic syndrome;
228	Bronchiolitis obliterans;Obliterating bronchiolitis;

Human T-cell leukemia virus 1 infection 💬

[1] IL2RA 💬

Daclizumab 💬

Daclizumab

[8] 13, 56, 60, 65, 97, 107, 283, 284 💬

Disease ID	Name
13	Multiple sclerosis/Neuromyelitis optica;
56	Behcet disease;Behçet disease;BD;
60	Aplastic anemia;
65	Primary immunodeficiency;
97	Ulcerative colitis;
107	Juvenile idiopathic arthritis;JIA;
283	Acquired pure red cell aplasia;Pure red cell aplasia;
284	Diamond-Blackfan anemia;

Human T-cell leukemia virus 1 infection 💬

[3] IL2RA, IL2RB, IL2RG 💬

Aldesleukin 💬

Aldesleukin

[6] 2 , 35, 49, 65, 96, 97 💬

JAK-STAT signaling pathway 💬

[1] IL2RA 💬

Basiliximab 💬

Basiliximab

[6] 2 , 50, 66, 97, 222, 228 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
50	Dermatomyositis;Polymyositis;
66	IgA nephropathy;IgA nephritis;Berger disease;IgA-IgG nephropathy;
97	Ulcerative colitis;
222	Primary nephrotic syndrome;
228	Bronchiolitis obliterans;Obliterating bronchiolitis;

JAK-STAT signaling pathway 💬

[1] IL2RA 💬

Daclizumab 💬

Daclizumab

[8] 13, 56, 60, 65, 97, 107, 283, 284 💬

Disease ID	Name
13	Multiple sclerosis/Neuromyelitis optica;
56	Behcet disease;Behçet disease;BD;
60	Aplastic anemia;
65	Primary immunodeficiency;
97	Ulcerative colitis;
107	Juvenile idiopathic arthritis;JIA;
283	Acquired pure red cell aplasia;Pure red cell aplasia;
284	Diamond-Blackfan anemia;

JAK-STAT signaling pathway 💬

[3] IL2RA, IL2RB, IL2RG 💬

Aldesleukin 💬

Aldesleukin

[6] 2 , 35, 49, 65, 96, 97 💬

Measles 💬

[1] IL2RA 💬

Basiliximab 💬

Basiliximab

[6] 2 , 50, 66, 97, 222, 228 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
50	Dermatomyositis;Polymyositis;
66	IgA nephropathy;IgA nephritis;Berger disease;IgA-IgG nephropathy;
97	Ulcerative colitis;
222	Primary nephrotic syndrome;
228	Bronchiolitis obliterans;Obliterating bronchiolitis;

Measles 💬

[1] IL2RA 💬

Daclizumab 💬

Daclizumab

[8] 13, 56, 60, 65, 97, 107, 283, 284 💬

Disease ID	Name
13	Multiple sclerosis/Neuromyelitis optica;
56	Behcet disease;Behçet disease;BD;
60	Aplastic anemia;
65	Primary immunodeficiency;
97	Ulcerative colitis;
107	Juvenile idiopathic arthritis;JIA;
283	Acquired pure red cell aplasia;Pure red cell aplasia;
284	Diamond-Blackfan anemia;

Measles 💬

[3] IL2RA, IL2RB, IL2RG 💬

Aldesleukin 💬

Aldesleukin

[6] 2 , 35, 49, 65, 96, 97 💬

Pathways in cancer 💬

[1] IL2RA 💬

Basiliximab 💬

Basiliximab

[6] 2 , 50, 66, 97, 222, 228 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
50	Dermatomyositis;Polymyositis;
66	IgA nephropathy;IgA nephritis;Berger disease;IgA-IgG nephropathy;
97	Ulcerative colitis;
222	Primary nephrotic syndrome;
228	Bronchiolitis obliterans;Obliterating bronchiolitis;

Pathways in cancer 💬

[1] IL2RA 💬

Daclizumab 💬

Daclizumab

[8] 13, 56, 60, 65, 97, 107, 283, 284 💬

Disease ID	Name
13	Multiple sclerosis/Neuromyelitis optica;
56	Behcet disease;Behçet disease;BD;
60	Aplastic anemia;
65	Primary immunodeficiency;
97	Ulcerative colitis;
107	Juvenile idiopathic arthritis;JIA;
283	Acquired pure red cell aplasia;Pure red cell aplasia;
284	Diamond-Blackfan anemia;

Pathways in cancer 💬

[3] IL2RA, IL2RB, IL2RG 💬

Aldesleukin 💬

Aldesleukin

[6] 2 , 35, 49, 65, 96, 97 💬

PI3K-Akt signaling pathway 💬

[1] IL2RA 💬

Basiliximab 💬

Basiliximab

[6] 2 , 50, 66, 97, 222, 228 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
50	Dermatomyositis;Polymyositis;
66	IgA nephropathy;IgA nephritis;Berger disease;IgA-IgG nephropathy;
97	Ulcerative colitis;
222	Primary nephrotic syndrome;
228	Bronchiolitis obliterans;Obliterating bronchiolitis;

PI3K-Akt signaling pathway 💬

[1] IL2RA 💬

Daclizumab 💬

Daclizumab

[8] 13, 56, 60, 65, 97, 107, 283, 284 💬

Disease ID	Name
13	Multiple sclerosis/Neuromyelitis optica;
56	Behcet disease;Behçet disease;BD;
60	Aplastic anemia;
65	Primary immunodeficiency;
97	Ulcerative colitis;
107	Juvenile idiopathic arthritis;JIA;
283	Acquired pure red cell aplasia;Pure red cell aplasia;
284	Diamond-Blackfan anemia;

PI3K-Akt signaling pathway 💬

[3] IL2RA, IL2RB, IL2RG 💬

Aldesleukin 💬

Aldesleukin

[6] 2 , 35, 49, 65, 96, 97 💬

Th1 and Th2 cell differentiation 💬

[1] IL2RA 💬

Basiliximab 💬

Basiliximab

[6] 2 , 50, 66, 97, 222, 228 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
50	Dermatomyositis;Polymyositis;
66	IgA nephropathy;IgA nephritis;Berger disease;IgA-IgG nephropathy;
97	Ulcerative colitis;
222	Primary nephrotic syndrome;
228	Bronchiolitis obliterans;Obliterating bronchiolitis;

Th1 and Th2 cell differentiation 💬

[1] IL2RA 💬

Daclizumab 💬

Daclizumab

[8] 13, 56, 60, 65, 97, 107, 283, 284 💬

Disease ID	Name
13	Multiple sclerosis/Neuromyelitis optica;
56	Behcet disease;Behçet disease;BD;
60	Aplastic anemia;
65	Primary immunodeficiency;
97	Ulcerative colitis;
107	Juvenile idiopathic arthritis;JIA;
283	Acquired pure red cell aplasia;Pure red cell aplasia;
284	Diamond-Blackfan anemia;

Th1 and Th2 cell differentiation 💬

[3] IL2RA, IL2RB, IL2RG 💬

Aldesleukin 💬

Aldesleukin

[6] 2 , 35, 49, 65, 96, 97 💬

Th17 cell differentiation 💬

[1] IL2RA 💬

Basiliximab 💬

Basiliximab

[6] 2 , 50, 66, 97, 222, 228 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
50	Dermatomyositis;Polymyositis;
66	IgA nephropathy;IgA nephritis;Berger disease;IgA-IgG nephropathy;
97	Ulcerative colitis;
222	Primary nephrotic syndrome;
228	Bronchiolitis obliterans;Obliterating bronchiolitis;

Th17 cell differentiation 💬

[1] IL2RA 💬

Daclizumab 💬

Daclizumab

[8] 13, 56, 60, 65, 97, 107, 283, 284 💬

Disease ID	Name
13	Multiple sclerosis/Neuromyelitis optica;
56	Behcet disease;Behçet disease;BD;
60	Aplastic anemia;
65	Primary immunodeficiency;
97	Ulcerative colitis;
107	Juvenile idiopathic arthritis;JIA;
283	Acquired pure red cell aplasia;Pure red cell aplasia;
284	Diamond-Blackfan anemia;

Th17 cell differentiation 💬

[3] IL2RA, IL2RB, IL2RG 💬

Aldesleukin 💬

Aldesleukin

[6] 2 , 35, 49, 65, 96, 97 💬

Viral protein interaction with cytokine and cytokine receptor 💬

[1] IL2RA 💬

Basiliximab 💬

Basiliximab

[6] 2 , 50, 66, 97, 222, 228 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
50	Dermatomyositis;Polymyositis;
66	IgA nephropathy;IgA nephritis;Berger disease;IgA-IgG nephropathy;
97	Ulcerative colitis;
222	Primary nephrotic syndrome;
228	Bronchiolitis obliterans;Obliterating bronchiolitis;

Viral protein interaction with cytokine and cytokine receptor 💬

[1] IL2RA 💬

Daclizumab 💬

Daclizumab

[8] 13, 56, 60, 65, 97, 107, 283, 284 💬

Disease ID	Name
13	Multiple sclerosis/Neuromyelitis optica;
56	Behcet disease;Behçet disease;BD;
60	Aplastic anemia;
65	Primary immunodeficiency;
97	Ulcerative colitis;
107	Juvenile idiopathic arthritis;JIA;
283	Acquired pure red cell aplasia;Pure red cell aplasia;
284	Diamond-Blackfan anemia;

Viral protein interaction with cytokine and cytokine receptor 💬

[3] IL2RA, IL2RB, IL2RG 💬

Aldesleukin 💬

Aldesleukin

[6] 2 , 35, 49, 65, 96, 97 💬