Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Estrogen signaling pathway 💬
 [1] OPRM1 💬 Buprenorphine 💬 Buprenorphine [2] 46, 70 💬
2 Estrogen signaling pathway 💬
 [1] OPRM1 💬 Dezocine 💬 Dezocine [1] 46 💬
3 Estrogen signaling pathway 💬
 [1] OPRM1 💬 Dihydrocodeine 💬 Dihydrocodeine [1] 310 💬
4 Estrogen signaling pathway 💬
 [1] OPRM1 💬 Fentanyl 💬 Fentanyl [3] 46, 70, 215 💬
5 Estrogen signaling pathway 💬
 [1] OPRM1 💬 Hydromorphone 💬 Hydromorphone [1] 70 💬
6 Estrogen signaling pathway 💬
 [1] OPRM1 💬 Loperamide 💬 Loperamide [2] 13, 97 💬
7 Estrogen signaling pathway 💬
 [1] OPRM1 💬 Morphine 💬 Morphine [5] 36, 46, 70, 85, 86 💬
8 Estrogen signaling pathway 💬
 [1] OPRM1 💬 Nalbuphine 💬 Nalbuphine [1] 85 💬
9 Estrogen signaling pathway 💬
 [1] OPRM1 💬 Nalmefene 💬 Nalmefene [1]  6  💬
10 Estrogen signaling pathway 💬
 [1] OPRM1 💬 Naloxone 💬 Naloxone [2]  6 , 226 💬
11 Estrogen signaling pathway 💬
 [1] OPRM1 💬 Naltrexone 💬 Naltrexone [13]  6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬
12 Estrogen signaling pathway 💬
 [1] OPRM1 💬 Oxycodone 💬 Oxycodone [5]  6 , 13, 70, 226, 298 💬
13 Estrogen signaling pathway 💬
 [1] OPRM1 💬 Oxymorphone 💬 Oxymorphone [1] 70 💬
14 Estrogen signaling pathway 💬
 [1] OPRM1 💬 Remifentanil 💬 Remifentanil [2]  6 , 70 💬
15 Estrogen signaling pathway 💬
 [1] OPRM1 💬 Sufentanil 💬 Sufentanil [2] 70, 280 💬
16 Estrogen signaling pathway 💬
 [1] OPRM1 💬 Tramadol 💬 Tramadol [5] 46, 70, 78, 226, 271 💬
17 Estrogen signaling pathway 💬
 [1] OPRM1 💬 Trimebutine 💬 Trimebutine [1] 51 💬
18 Morphine addiction 💬
 [1] OPRM1 💬 Buprenorphine 💬 Buprenorphine [2] 46, 70 💬
19 Morphine addiction 💬
 [1] OPRM1 💬 Dezocine 💬 Dezocine [1] 46 💬
20 Morphine addiction 💬
 [1] OPRM1 💬 Dihydrocodeine 💬 Dihydrocodeine [1] 310 💬
21 Morphine addiction 💬
 [1] OPRM1 💬 Fentanyl 💬 Fentanyl [3] 46, 70, 215 💬
22 Morphine addiction 💬
 [1] OPRM1 💬 Hydromorphone 💬 Hydromorphone [1] 70 💬
23 Morphine addiction 💬
 [1] OPRM1 💬 Loperamide 💬 Loperamide [2] 13, 97 💬
24 Morphine addiction 💬
 [1] OPRM1 💬 Morphine 💬 Morphine [5] 36, 46, 70, 85, 86 💬
25 Morphine addiction 💬
 [1] OPRM1 💬 Nalbuphine 💬 Nalbuphine [1] 85 💬
26 Morphine addiction 💬
 [1] OPRM1 💬 Nalmefene 💬 Nalmefene [1]  6  💬
27 Morphine addiction 💬
 [1] OPRM1 💬 Naloxone 💬 Naloxone [2]  6 , 226 💬
28 Morphine addiction 💬
 [1] OPRM1 💬 Naltrexone 💬 Naltrexone [13]  6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬
29 Morphine addiction 💬
 [1] OPRM1 💬 Oxycodone 💬 Oxycodone [5]  6 , 13, 70, 226, 298 💬
30 Morphine addiction 💬
 [1] OPRM1 💬 Oxymorphone 💬 Oxymorphone [1] 70 💬
31 Morphine addiction 💬
 [1] OPRM1 💬 Remifentanil 💬 Remifentanil [2]  6 , 70 💬
32 Morphine addiction 💬
 [1] OPRM1 💬 Sufentanil 💬 Sufentanil [2] 70, 280 💬
33 Morphine addiction 💬
 [1] OPRM1 💬 Tramadol 💬 Tramadol [5] 46, 70, 78, 226, 271 💬
34 Morphine addiction 💬
 [1] OPRM1 💬 Trimebutine 💬 Trimebutine [1] 51 💬
35 Neuroactive ligand-receptor interaction 💬
 [3] OPRD1, OPRK1, OPRM1 💬 Loperamide 💬 Loperamide [2] 13, 97 💬
36 Neuroactive ligand-receptor interaction 💬
 [3] OPRD1, OPRK1, OPRM1 💬 Nalbuphine 💬 Nalbuphine [1] 85 💬
37 Neuroactive ligand-receptor interaction 💬
 [3] OPRD1, OPRK1, OPRM1 💬 Nalmefene 💬 Nalmefene [1]  6  💬
38 Neuroactive ligand-receptor interaction 💬
 [3] OPRD1, OPRK1, OPRM1 💬 Naloxone 💬 Naloxone [2]  6 , 226 💬
39 Neuroactive ligand-receptor interaction 💬
 [3] OPRD1, OPRK1, OPRM1 💬 Naltrexone 💬 Naltrexone [13]  6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬
40 Neuroactive ligand-receptor interaction 💬
 [3] OPRD1, OPRK1, OPRM1 💬 Oxycodone 💬 Oxycodone [5]  6 , 13, 70, 226, 298 💬
41 Neuroactive ligand-receptor interaction 💬
 [2] OPRK1, OPRM1 💬 Buprenorphine 💬 Buprenorphine [2] 46, 70 💬
42 Neuroactive ligand-receptor interaction 💬
 [2] OPRK1, OPRM1 💬 Dezocine 💬 Dezocine [1] 46 💬
43 Neuroactive ligand-receptor interaction 💬
 [2] OPRK1, OPRM1 💬 Trimebutine 💬 Trimebutine [1] 51 💬
44 Neuroactive ligand-receptor interaction 💬
 [1] OPRM1 💬 Dihydrocodeine 💬 Dihydrocodeine [1] 310 💬
45 Neuroactive ligand-receptor interaction 💬
 [1] OPRM1 💬 Fentanyl 💬 Fentanyl [3] 46, 70, 215 💬
46 Neuroactive ligand-receptor interaction 💬
 [1] OPRM1 💬 Hydromorphone 💬 Hydromorphone [1] 70 💬
47 Neuroactive ligand-receptor interaction 💬
 [1] OPRM1 💬 Morphine 💬 Morphine [5] 36, 46, 70, 85, 86 💬
48 Neuroactive ligand-receptor interaction 💬
 [1] OPRM1 💬 Oxymorphone 💬 Oxymorphone [1] 70 💬
49 Neuroactive ligand-receptor interaction 💬
 [1] OPRM1 💬 Remifentanil 💬 Remifentanil [2]  6 , 70 💬
50 Neuroactive ligand-receptor interaction 💬
 [1] OPRM1 💬 Sufentanil 💬 Sufentanil [2] 70, 280 💬
51 Neuroactive ligand-receptor interaction 💬
 [1] OPRM1 💬 Tramadol 💬 Tramadol [5] 46, 70, 78, 226, 271 💬

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