Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Rap1 signaling pathway 💬
 [1] ADORA2A 💬 Caffeine 💬 Caffeine [8]  2 ,  6 , 21, 46, 78, 96, 97, 265 💬
2 Rap1 signaling pathway 💬
 [1] ADORA2A 💬 Caffeine hydrate 💬 Caffeine [8]  2 ,  6 , 21, 46, 78, 96, 97, 265 💬
3 Rap1 signaling pathway 💬
 [1] ADORA2A 💬 Istradefylline 💬 Istradefylline [1]  6  💬
4 Rap1 signaling pathway 💬
 [1] ADORA2A 💬 Preladenant 💬 Preladenant [1]  6  💬
5 Rap1 signaling pathway 💬
 [1] ADORA2A 💬 Regadenoson 💬 Regadenoson [1] 58 💬
6 Rap1 signaling pathway 💬
 [1] ADORA2A 💬 Regadenoson 💬 Regadenoson [1] 58 💬
7 Rap1 signaling pathway 💬
 [1] ADORA2A 💬 Tozadenant 💬 Tozadenant [1]  6  💬
8 Rap1 signaling pathway 💬
 [2] ADORA2A, ADORA2B 💬 Adenosine 💬 Adenosine [3] 13, 58, 65 💬
9 Rap1 signaling pathway 💬
 [2] ADORA2A, ADORA2B 💬 Adenosine phosphate 💬 Adenosine phosphate [1] 46 💬
10 Rap1 signaling pathway 💬
 [1] ADORA2B 💬 Aminophylline 💬 Aminophylline [1] 63 💬
11 Rap1 signaling pathway 💬
 [1] ADORA2B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
12 Rap1 signaling pathway 💬
 [1] ADORA2B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
13 Rap1 signaling pathway 💬
 [1] BRAF 💬 Dabrafenib 💬 Dabrafenib [1] 34 💬
14 Rap1 signaling pathway 💬
 [6] BRAF, FLT4, KDR, KIT, PDGFRB, RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
15 Rap1 signaling pathway 💬
 [1] CNR1 💬 Cannabidiol 💬 Cannabidiol [20]  2 ,  6 ,  8 , 13, 36, 46, 51, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬
16 Rap1 signaling pathway 💬
 [1] CNR1 💬 Dronabinol 💬 Dronabinol [8]  2 ,  8 , 13, 36, 46, 96, 271, 298 💬
17 Rap1 signaling pathway 💬
 [1] CNR1 💬 Nabilone 💬 Nabilone [3]  6 , 13, 127 💬
18 Rap1 signaling pathway 💬
 [1] CNR1 💬 Rimonabant 💬 Rimonabant [1] 193 💬
19 Rap1 signaling pathway 💬
 [7] CSF1R, FLT1, FLT4, KDR, KIT, PDGFRA, PDGFRB 💬 Sunitinib 💬 Sunitinib [2] 28, 34 💬
20 Rap1 signaling pathway 💬
 [2] CSF1R, KIT 💬 Pexidartinib 💬 Pexidartinib [1] 34 💬
21 Rap1 signaling pathway 💬
 [1] DRD2 💬 Apomorphine 💬 Apomorphine [3]  5 ,  6 ,  7  💬
22 Rap1 signaling pathway 💬
 [1] DRD2 💬 Aripiprazole 💬 Aripiprazole [2]  6 , 206 💬
23 Rap1 signaling pathway 💬
 [1] DRD2 💬 Bromocriptine 💬 Bromocriptine [2]  6 , 74 💬
24 Rap1 signaling pathway 💬
 [1] DRD2 💬 Buspirone 💬 Buspirone [2]  6 , 51 💬
25 Rap1 signaling pathway 💬
 [1] DRD2 💬 Cabergoline 💬 Cabergoline [3]  6 , 74, 75 💬
26 Rap1 signaling pathway 💬
 [1] DRD2 💬 Cariprazine 💬 Cariprazine [1] 21 💬
27 Rap1 signaling pathway 💬
 [1] DRD2 💬 Chlorpromazine 💬 Chlorpromazine [1] 254 💬
28 Rap1 signaling pathway 💬
 [1] DRD2 💬 Dexpramipexole 💬 Dexpramipexole [1]  2  💬
29 Rap1 signaling pathway 💬
 [1] DRD2 💬 Domperidone 💬 Domperidone [5]  6 , 13, 17, 51, 230 💬
30 Rap1 signaling pathway 💬
 [1] DRD2 💬 Domperidone maleate 💬 Domperidone [5]  6 , 13, 17, 51, 230 💬
31 Rap1 signaling pathway 💬
 [1] DRD2 💬 Dopamine 💬 Dopamine [4]  6 ,  7 , 74, 299 💬
32 Rap1 signaling pathway 💬
 [1] DRD2 💬 Flupentixol 💬 Flupentixol [1] 97 💬
33 Rap1 signaling pathway 💬
 [1] DRD2 💬 Foslevodopa 💬 Foslevodopa [1]  6  💬
34 Rap1 signaling pathway 💬
 [1] DRD2 💬 Haloperidol 💬 Haloperidol [1]  8  💬
35 Rap1 signaling pathway 💬
 [1] DRD2 💬 Iloperidone 💬 Iloperidone [1]  6  💬
36 Rap1 signaling pathway 💬
 [1] DRD2 💬 Levodopa 💬 Levodopa [6]  6 , 17, 90, 140, 164, 201 💬
37 Rap1 signaling pathway 💬
 [1] DRD2 💬 Lisuride 💬 Lisuride [2]  6 , 86 💬
38 Rap1 signaling pathway 💬
 [1] DRD2 💬 Melperone 💬 Melperone [1]  6  💬
39 Rap1 signaling pathway 💬
 [1] DRD2 💬 Metoclopramide 💬 Metoclopramide [2] 46, 51 💬
40 Rap1 signaling pathway 💬
 [1] DRD2 💬 Olanzapine 💬 Olanzapine [2]  2 ,  8  💬
41 Rap1 signaling pathway 💬
 [1] DRD2 💬 Pardoprunox 💬 Pardoprunox [1]  6  💬
42 Rap1 signaling pathway 💬
 [1] DRD2 💬 Pergolide 💬 Pergolide [1]  6  💬
43 Rap1 signaling pathway 💬
 [1] DRD2 💬 Pimozide 💬 Pimozide [1]  2  💬
44 Rap1 signaling pathway 💬
 [1] DRD2 💬 Piribedil 💬 Piribedil [1]  6  💬
45 Rap1 signaling pathway 💬
 [1] DRD2 💬 Pramipexole 💬 Pramipexole [3]  2 ,  6 , 20 💬
46 Rap1 signaling pathway 💬
 [1] DRD2 💬 Pridopidine 💬 Pridopidine [3]  2 ,  6 ,  8  💬
47 Rap1 signaling pathway 💬
 [1] DRD2 💬 Quetiapine 💬 Quetiapine [2]  6 , 13 💬
48 Rap1 signaling pathway 💬
 [1] DRD2 💬 Risperidone 💬 Risperidone [5]  8 , 156, 179, 187, 206 💬
49 Rap1 signaling pathway 💬
 [1] DRD2 💬 Ropinirole 💬 Ropinirole [4]  2 ,  6 , 74, 309 💬
50 Rap1 signaling pathway 💬
 [1] DRD2 💬 Rotigotine 💬 Rotigotine [1]  6  💬
51 Rap1 signaling pathway 💬
 [1] DRD2 💬 Sulpiride 💬 Sulpiride [2]  6 , 70 💬
52 Rap1 signaling pathway 💬
 [1] DRD2 💬 Terguride 💬 Terguride [2] 51, 86 💬
53 Rap1 signaling pathway 💬
 [1] DRD2 💬 Tiapride 💬 Tiapride [1]  8  💬
54 Rap1 signaling pathway 💬
 [1] DRD2 💬 Trifluoperazine maleate 💬 Trifluoperazine [2] 283, 284 💬
55 Rap1 signaling pathway 💬
 [1] DRD2 💬 Trifluoperazine 💬 Trifluoperazine [2] 283, 284 💬
56 Rap1 signaling pathway 💬
 [1] EGFR 💬 Cetuximab 💬 Cetuximab [2] 51, 86 💬
57 Rap1 signaling pathway 💬
 [1] EGFR 💬 Erlotinib 💬 Erlotinib [1] 94 💬
58 Rap1 signaling pathway 💬
 [1] EGFR 💬 Gefitinib 💬 Gefitinib [1] 75 💬
59 Rap1 signaling pathway 💬
 [1] EGFR 💬 Icotinib 💬 Icotinib [1] 34 💬
60 Rap1 signaling pathway 💬
 [1] EGFR 💬 Lapatinib 💬 Lapatinib [3] 34, 74, 75 💬
61 Rap1 signaling pathway 💬
 [1] EGFR 💬 Neratinib 💬 Neratinib [1] 34 💬
62 Rap1 signaling pathway 💬
 [3] EGFR, FLT4, KDR 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
63 Rap1 signaling pathway 💬
 [4] EPHA2, KIT, PDGFRB, SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
64 Rap1 signaling pathway 💬
 [4] EPHA2, KIT, PDGFRB, SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
65 Rap1 signaling pathway 💬
 [1] FGF23 💬 Burosumab 💬 Burosumab [1] 238 💬
66 Rap1 signaling pathway 💬
 [3] FGFR1, FGFR2, FGFR3 💬 Infigratinib 💬 Infigratinib [1] 276 💬
67 Rap1 signaling pathway 💬
 [8] FGFR1, FGFR2, FGFR3, FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬 Nintedanib 💬 Nintedanib [5] 51, 85, 89, 227, 228 💬
68 Rap1 signaling pathway 💬
 [1] FGFR2 💬 Palifermin 💬 Palifermin [5] 13, 36, 38, 39, 65 💬
69 Rap1 signaling pathway 💬
 [3] FLT1, FLT4, KDR 💬 Axitinib 💬 Axitinib [1] 34 💬
70 Rap1 signaling pathway 💬
 [3] FLT1, FLT4, KDR 💬 Cediranib 💬 Cediranib [1] 34 💬
71 Rap1 signaling pathway 💬
 [3] GRIN1, GRIN2A, GRIN2B 💬 Acamprosate 💬 Acamprosate [2]  6 , 206 💬
72 Rap1 signaling pathway 💬
 [3] GRIN1, GRIN2A, GRIN2B 💬 Amantadine 💬 Amantadine [4]  6 ,  8 , 13, 127 💬
73 Rap1 signaling pathway 💬
 [3] GRIN1, GRIN2A, GRIN2B 💬 Dextromethorphan 💬 Dextromethorphan [11]  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
74 Rap1 signaling pathway 💬
 [3] GRIN1, GRIN2A, GRIN2B 💬 Esketamine 💬 Esketamine [3]  2 ,  4 , 70 💬
75 Rap1 signaling pathway 💬
 [3] GRIN1, GRIN2A, GRIN2B 💬 Ketamine 💬 Ketamine [8]  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬
76 Rap1 signaling pathway 💬
 [3] GRIN1, GRIN2A, GRIN2B 💬 Latrepirdine 💬 Latrepirdine [1]  8  💬
77 Rap1 signaling pathway 💬
 [3] GRIN1, GRIN2A, GRIN2B 💬 Memantine 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
78 Rap1 signaling pathway 💬
 [3] GRIN1, GRIN2A, GRIN2B 💬 Riluzole 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
79 Rap1 signaling pathway 💬
 [1] IGF1R 💬 Linsitinib 💬 Linsitinib [1] 232 💬
80 Rap1 signaling pathway 💬
 [1] IGF1R 💬 Mecasermin 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
81 Rap1 signaling pathway 💬
 [1] IGF1R 💬 Teprotumumab 💬 Teprotumumab [1] 51 💬
82 Rap1 signaling pathway 💬
 [1] INSR 💬 Insulin detemir 💬 Insulin detemir [1] 299 💬
83 Rap1 signaling pathway 💬
 [1] INSR 💬 Insulin glargine 💬 Insulin glargine [1] 299 💬
84 Rap1 signaling pathway 💬
 [1] INSR 💬 Insulin human 💬 Insulin human [2] 96, 156 💬
85 Rap1 signaling pathway 💬
 [1] ITGAL 💬 Efalizumab 💬 Efalizumab [9] 11, 13, 37, 46, 49, 53, 61, 95, 96 💬
86 Rap1 signaling pathway 💬
 [2] KDR, MET 💬 Cabozantinib 💬 Cabozantinib [1] 34 💬
87 Rap1 signaling pathway 💬
 [1] KIT 💬 Masitinib 💬 Masitinib [6]  2 ,  5 ,  6 , 13, 46, 96 💬
88 Rap1 signaling pathway 💬
 [2] KIT, PDGFRA 💬 Imatinib 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
89 Rap1 signaling pathway 💬
 [3] KIT, PDGFRA, PDGFRB 💬 Nilotinib 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
90 Rap1 signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 Binimetinib 💬 Binimetinib [1] 34 💬
91 Rap1 signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 Cobimetinib 💬 Cobimetinib [1] 280 💬
92 Rap1 signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 Mirdametinib 💬 Mirdametinib [1] 34 💬
93 Rap1 signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 Selumetinib 💬 Selumetinib [1] 34 💬
94 Rap1 signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 Trametinib 💬 Trametinib [4]  2 , 34, 279, 280 💬
95 Rap1 signaling pathway 💬
 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 Losmapimod 💬 Losmapimod [2] 113, 222 💬
96 Rap1 signaling pathway 💬
 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 Neflamapimod 💬 Neflamapimod [1]  8  💬
97 Rap1 signaling pathway 💬
 [1] NGF 💬 Tanezumab 💬 Tanezumab [2] 226, 298 💬
98 Rap1 signaling pathway 💬
 [1] NGFR 💬 Cenegermin 💬 Cenegermin [2] 53, 90 💬
99 Rap1 signaling pathway 💬
 [3] PGF, VEGFA, VEGFB 💬 Aflibercept 💬 Aflibercept [2] 90, 166 💬
100 Rap1 signaling pathway 💬
 [1] PIK3CA 💬 Alpelisib 💬 Alpelisib [1] 138 💬
101 Rap1 signaling pathway 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 Leniolisib 💬 Leniolisib [2] 53, 65 💬
102 Rap1 signaling pathway 💬
 [1] PIK3CD 💬 Parsaclisib 💬 Parsaclisib [3] 35, 53, 61 💬
103 Rap1 signaling pathway 💬
 [1] PRKCB 💬 Enzastaurin 💬 Enzastaurin [1] 168 💬
104 Rap1 signaling pathway 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
105 Rap1 signaling pathway 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
106 Rap1 signaling pathway 💬
 [1] VEGFA 💬 Bevacizumab 💬 Bevacizumab [6] 13, 34, 85, 87, 227, 280 💬
107 Rap1 signaling pathway 💬
 [1] VEGFA 💬 Ranibizumab 💬 Ranibizumab [4] 34, 166, 227, 301 💬