Target Gene/Pathway Pathway / Gene

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	Disease ID
1	Apoptosis 💬	[1] BCL2 💬	D10679 💬	Venetoclax	[1] 28 💬
2	Apoptosis 💬	[1] CASP9 💬	D11195 💬	Rimiducid	[6] 19, 60, 65, 284, 285, 326 💬
3	Apoptosis 💬	[1] CTSC 💬	D12120 💬	Brensocatib	[1] 299 💬
4	Apoptosis 💬	[2] MAP2K1, MAP2K2 💬	D10604 💬	Binimetinib	[1] 34 💬
5	Apoptosis 💬	[2] MAP2K1, MAP2K2 💬	D10405 💬	Cobimetinib	[1] 280 💬
6	Apoptosis 💬	[2] MAP2K1, MAP2K2 💬	D11675 💬	Mirdametinib	[1] 34 💬
7	Apoptosis 💬	[2] MAP2K1, MAP2K2 💬	D09666 💬	Selumetinib	[1] 34 💬
8	Apoptosis 💬	[2] MAP2K1, MAP2K2 💬	D10175 💬	Trametinib	[4] 2 , 34, 279, 280 💬
9	Apoptosis 💬	[1] MAP3K5 💬	D10988 💬	Selonsertib	[1] 86 💬
10	Apoptosis 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[5] 46, 51, 53, 271, 300 💬

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