Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Focal adhesion 💬
 [1] BCL2 💬 Venetoclax 💬 Venetoclax [1] 28 💬
2 Focal adhesion 💬
 [1] BRAF 💬 Dabrafenib 💬 Dabrafenib [1] 34 💬
3 Focal adhesion 💬
 [5] BRAF, FLT4, KDR, PDGFRB, RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
4 Focal adhesion 💬
 [1] EGFR 💬 Cetuximab 💬 Cetuximab [2] 51, 86 💬
5 Focal adhesion 💬
 [1] EGFR 💬 Erlotinib 💬 Erlotinib [1] 94 💬
6 Focal adhesion 💬
 [1] EGFR 💬 Gefitinib 💬 Gefitinib [1] 75 💬
7 Focal adhesion 💬
 [1] EGFR 💬 Icotinib 💬 Icotinib [1] 34 💬
8 Focal adhesion 💬
 [2] EGFR, ERBB2 💬 Lapatinib 💬 Lapatinib [3] 34, 74, 75 💬
9 Focal adhesion 💬
 [2] EGFR, ERBB2 💬 Neratinib 💬 Neratinib [1] 34 💬
10 Focal adhesion 💬
 [4] EGFR, ERBB2, FLT4, KDR 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
11 Focal adhesion 💬
 [3] FLT1, FLT4, KDR 💬 Axitinib 💬 Axitinib [1] 34 💬
12 Focal adhesion 💬
 [3] FLT1, FLT4, KDR 💬 Cediranib 💬 Cediranib [1] 34 💬
13 Focal adhesion 💬
 [5] FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬 Nintedanib 💬 Nintedanib [5] 51, 85, 89, 227, 228 💬
14 Focal adhesion 💬
 [5] FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬 Sunitinib 💬 Sunitinib [2] 28, 34 💬
15 Focal adhesion 💬
 [3] FYN, PDGFRB, SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
16 Focal adhesion 💬
 [3] FYN, PDGFRB, SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
17 Focal adhesion 💬
 [1] IGF1R 💬 Linsitinib 💬 Linsitinib [1] 232 💬
18 Focal adhesion 💬
 [1] IGF1R 💬 Mecasermin 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
19 Focal adhesion 💬
 [1] IGF1R 💬 Teprotumumab 💬 Teprotumumab [1] 51 💬
20 Focal adhesion 💬
 [1] ITGA4 💬 Firategrast 💬 Firategrast [1] 13 💬
21 Focal adhesion 💬
 [1] ITGA4 💬 Natalizumab 💬 Natalizumab [6] 13, 15, 25, 46, 63, 96 💬
22 Focal adhesion 💬
 [2] ITGA4, ITGB7 💬 Abrilumab 💬 Abrilumab [2] 96, 97 💬
23 Focal adhesion 💬
 [2] ITGA4, ITGB7 💬 Vedolizumab 💬 Vedolizumab [3] 94, 96, 97 💬
24 Focal adhesion 💬
 [1] ITGB7 💬 Etrolizumab 💬 Etrolizumab [2] 96, 97 💬
25 Focal adhesion 💬
 [2] KDR, MET 💬 Cabozantinib 💬 Cabozantinib [1] 34 💬
26 Focal adhesion 💬
 [1] MAP2K1 💬 Binimetinib 💬 Binimetinib [1] 34 💬
27 Focal adhesion 💬
 [1] MAP2K1 💬 Cobimetinib 💬 Cobimetinib [1] 280 💬
28 Focal adhesion 💬
 [1] MAP2K1 💬 Mirdametinib 💬 Mirdametinib [1] 34 💬
29 Focal adhesion 💬
 [1] MAP2K1 💬 Selumetinib 💬 Selumetinib [1] 34 💬
30 Focal adhesion 💬
 [1] MAP2K1 💬 Trametinib 💬 Trametinib [4]  2 , 34, 279, 280 💬
31 Focal adhesion 💬
 [1] PDGFRA 💬 Imatinib 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
32 Focal adhesion 💬
 [2] PDGFRA, PDGFRB 💬 Nilotinib 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
33 Focal adhesion 💬
 [3] PGF, VEGFA, VEGFB 💬 Aflibercept 💬 Aflibercept [2] 90, 166 💬
34 Focal adhesion 💬
 [1] PIK3CA 💬 Alpelisib 💬 Alpelisib [1] 138 💬
35 Focal adhesion 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 Leniolisib 💬 Leniolisib [2] 53, 65 💬
36 Focal adhesion 💬
 [1] PIK3CD 💬 Parsaclisib 💬 Parsaclisib [3] 35, 53, 61 💬
37 Focal adhesion 💬
 [1] PRKCB 💬 Enzastaurin 💬 Enzastaurin [1] 168 💬
38 Focal adhesion 💬
 [2] ROCK1, ROCK2 💬 Fasudil 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
39 Focal adhesion 💬
 [1] ROCK2 💬 Belumosudil 💬 Belumosudil [2] 51, 85 💬
40 Focal adhesion 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
41 Focal adhesion 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
42 Focal adhesion 💬
 [1] VEGFA 💬 Bevacizumab 💬 Bevacizumab [6] 13, 34, 85, 87, 227, 280 💬
43 Focal adhesion 💬
 [1] VEGFA 💬 Ranibizumab 💬 Ranibizumab [4] 34, 166, 227, 301 💬
44 Focal adhesion 💬
 [1] VWF 💬 Caplacizumab 💬 Caplacizumab [1] 64 💬