Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Cell adhesion molecules 💬
 [1] CD22 💬 Epratuzumab 💬 Epratuzumab [1] 49 💬
2 Cell adhesion molecules 💬
 [1] CD274 💬 Atezolizumab 💬 Atezolizumab [1] 85 💬
3 Cell adhesion molecules 💬
 [1] CD274 💬 Durvalumab 💬 Durvalumab [1] 85 💬
4 Cell adhesion molecules 💬
 [1] CD4 💬 Zanolimumab 💬 Zanolimumab [1] 46 💬
5 Cell adhesion molecules 💬
 [1] CD40 💬 Bleselumab 💬 Bleselumab [1] 222 💬
6 Cell adhesion molecules 💬
 [1] CD40 💬 Iscalimab 💬 Iscalimab [2] 49, 53 💬
7 Cell adhesion molecules 💬
 [1] CD40 💬 Ravagalimab 💬 Ravagalimab [2] 53, 97 💬
8 Cell adhesion molecules 💬
 [1] CD40LG 💬 Toralizumab 💬 Toralizumab [1] 63 💬
9 Cell adhesion molecules 💬
 [1] CD58 💬 Alefacept 💬 Alefacept [6] 37, 60, 65, 164, 284, 285 💬
10 Cell adhesion molecules 💬
 [1] CD6 💬 Itolizumab 💬 Itolizumab [1] 49 💬
11 Cell adhesion molecules 💬
 [2] CD80, CD86 💬 Abatacept 💬 Abatacept [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
12 Cell adhesion molecules 💬
 [2] CD80, CD86 💬 Belatacept 💬 Belatacept [1] 46 💬
13 Cell adhesion molecules 💬
 [1] CTLA4 💬 Ipilimumab 💬 Ipilimumab [1] 159 💬
14 Cell adhesion molecules 💬
 [1] CTLA4 💬 Tremelimumab 💬 Tremelimumab [1] 96 💬
15 Cell adhesion molecules 💬
 [1] ITGA4 💬 Firategrast 💬 Firategrast [1] 13 💬
16 Cell adhesion molecules 💬
 [1] ITGA4 💬 Natalizumab 💬 Natalizumab [6] 13, 15, 25, 46, 63, 96 💬
17 Cell adhesion molecules 💬
 [2] ITGA4, ITGB7 💬 Abrilumab 💬 Abrilumab [2] 96, 97 💬
18 Cell adhesion molecules 💬
 [2] ITGA4, ITGB7 💬 Vedolizumab 💬 Vedolizumab [3] 94, 96, 97 💬
19 Cell adhesion molecules 💬
 [1] ITGAL 💬 Efalizumab 💬 Efalizumab [9] 11, 13, 37, 46, 49, 53, 61, 95, 96 💬
20 Cell adhesion molecules 💬
 [1] ITGB7 💬 Etrolizumab 💬 Etrolizumab [2] 96, 97 💬
21 Cell adhesion molecules 💬
 [1] PDCD1 💬 Nivolumab 💬 Nivolumab [12] 13, 26, 41, 46, 49, 50, 51, 53, 85, 96, 97, 159 💬
22 Cell adhesion molecules 💬
 [1] PDCD1 💬 Pembrolizumab 💬 Pembrolizumab [2] 25, 285 💬