Gene

Search results

No.

KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related

C-type lectin receptor signaling pathway 💬

[4] IL10, IL1B, IL6, TNF 💬

Pirfenidone 💬

Pirfenidone

[11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬

Disease ID	Name
13	Multiple sclerosis/Neuromyelitis optica;
34	Neurofibromatosis;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
50	Dermatomyositis;Polymyositis;
51	Scleroderma;Systemic sclerosis;SSc;
58	Hypertrophic cardiomyopathy;HCM;
84	Sarcoidosis;
85	Idiopathic interstitial pneumonia;IIPs;
164	Oculocutaneous albinism;
222	Primary nephrotic syndrome;
228	Bronchiolitis obliterans;Obliterating bronchiolitis;

C-type lectin receptor signaling pathway 💬

[3] IL12A, IL12B, IL23A 💬

Ustekinumab 💬

Ustekinumab

[16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬

Disease ID	Name
37	Generalised pustular psoriasis;Pustular psoriasis;
40	Takayasu arteritis;Aortitis syndrome;Pulseless disease;Aortitis syndrome;
41	Giant cell arteritis;Temporal arteritis;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
49	Systemic lupus erythematosus;SLE;
50	Dermatomyositis;Polymyositis;
56	Behcet disease;Behçet disease;BD;
65	Primary immunodeficiency;
84	Sarcoidosis;
93	Primary biliary cholangitis;Primary biliary cirrhosis;PBC;
96	Crohn disease;Terminal ileitis;
97	Ulcerative colitis;
160	Congenital ichthyosis;
162	Pemphigoid;
269	Pyogenic arthritis;Pyoderma gangrenosum;Acne syndrome;PAPA syndrome;
271	Ankylosing spondylitis;Spondylarthritis ankylopoietica;

C-type lectin receptor signaling pathway 💬

[1] IL1B 💬

Canakinumab 💬

Canakinumab

[10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬

Disease ID	Name
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
56	Behcet disease;Behçet disease;BD;
84	Sarcoidosis;
106	Cryopyrin-associated periodic syndrome;Cryopyrin associated periodic fever syndrome;
107	Juvenile idiopathic arthritis;JIA;
108	TNF receptor-associated periodic syndrome;
113	Muscular dystrophy;
266	Familial mediterranean fever;
267	Hyper-IgD syndrome;HIDS;Mevalonate kinase deffiency;Hyperimmunoglobulinemia D and periodic fever syndrome;
269	Pyogenic arthritis;Pyoderma gangrenosum;Acne syndrome;PAPA syndrome;

C-type lectin receptor signaling pathway 💬

[1] IL1B 💬

Gevokizumab 💬

Gevokizumab

[4] 41, 50, 56, 269 💬

C-type lectin receptor signaling pathway 💬

[1] IL1B 💬

Rilonacept 💬

Rilonacept

[4] 51, 106, 107, 266 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;
106	Cryopyrin-associated periodic syndrome;Cryopyrin associated periodic fever syndrome;
107	Juvenile idiopathic arthritis;JIA;
266	Familial mediterranean fever;

C-type lectin receptor signaling pathway 💬

[1] IL23A 💬

Brazikumab 💬

Brazikumab

[2] 96, 97 💬

C-type lectin receptor signaling pathway 💬

[1] IL23A 💬

Guselkumab 💬

Guselkumab

[5] 37, 41, 51, 96, 97 💬

Disease ID	Name
37	Generalised pustular psoriasis;Pustular psoriasis;
41	Giant cell arteritis;Temporal arteritis;
51	Scleroderma;Systemic sclerosis;SSc;
96	Crohn disease;Terminal ileitis;
97	Ulcerative colitis;

C-type lectin receptor signaling pathway 💬

[1] IL23A 💬

Mirikizumab 💬

Mirikizumab

[3] 37, 96, 97 💬

C-type lectin receptor signaling pathway 💬

[1] IL23A 💬

Risankizumab 💬

Risankizumab

[4] 37, 96, 97, 271 💬

C-type lectin receptor signaling pathway 💬

[1] IL23A 💬

Tildrakizumab 💬

Tildrakizumab

[2] 162, 271 💬

C-type lectin receptor signaling pathway 💬

[1] IL6 💬

Olokizumab 💬

Olokizumab

[2] 46, 96 💬

C-type lectin receptor signaling pathway 💬

[1] IL6 💬

Siltuximab 💬

Siltuximab

[2] 28, 331 💬

C-type lectin receptor signaling pathway 💬

[1] IL6 💬

Sirukumab 💬

Sirukumab

[2] 41, 46 💬

C-type lectin receptor signaling pathway 💬

[2] IL6, TNF 💬

Pomalidomide 💬

Pomalidomide

[5] 28, 51, 85, 227, 331 💬

Disease ID	Name
28	Systemic amyloidosis;AL amyloidosis;
51	Scleroderma;Systemic sclerosis;SSc;
85	Idiopathic interstitial pneumonia;IIPs;
227	Osler disease;Hereditary hemorrhagic telangiectasia;Osler-Weber-Rendu disease;
331	Idiopathic multicentric castleman disease;iMCD;Castleman disease;

C-type lectin receptor signaling pathway 💬

[4] MAPK11, MAPK12, MAPK13, MAPK14 💬

Losmapimod 💬

Losmapimod

[2] 113, 222 💬

C-type lectin receptor signaling pathway 💬

[4] MAPK11, MAPK12, MAPK13, MAPK14 💬

Neflamapimod 💬

Neflamapimod

[1] 8 💬

C-type lectin receptor signaling pathway 💬

[1] NFKB1 💬

Iguratimod 💬

Iguratimod

[5] 46, 51, 53, 271, 300 💬

Disease ID	Name
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
51	Scleroderma;Systemic sclerosis;SSc;
53	Sjogren syndrome;Sjögren syndrome;Syndrome Sjogren's;SS;Autoimmune exocrinopathy;
271	Ankylosing spondylitis;Spondylarthritis ankylopoietica;
300	IgG4-related disease;

C-type lectin receptor signaling pathway 💬

[1] PIK3CA 💬

Alpelisib 💬

Alpelisib

[1] 138 💬

C-type lectin receptor signaling pathway 💬

[3] PIK3CA, PIK3CB, PIK3CD 💬

Name	Full Name
PIK3CA	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
PIK3CB	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
PIK3CD	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta

Leniolisib 💬

Leniolisib

[2] 53, 65 💬

C-type lectin receptor signaling pathway 💬

[1] PIK3CD 💬

Parsaclisib 💬

Parsaclisib

[3] 35, 53, 61 💬

C-type lectin receptor signaling pathway 💬

[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬

Name	Full Name
PPP3CA	protein phosphatase 3 catalytic subunit alpha
PPP3CB	protein phosphatase 3 catalytic subunit beta
PPP3CC	protein phosphatase 3 catalytic subunit gamma
PPP3R1	protein phosphatase 3 regulatory subunit B, alpha
PPP3R2	protein phosphatase 3 regulatory subunit B, beta

Cyclosporine 💬

Cyclosporine

[44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬

Disease ID	Name
11	Myasthenia gravis;MG;
19	Lysosomal storage disease;Lysosomal disease;
20	Adrenoleukodystrophy;ALD;
26	HTLV-1-associated myelopathy;Tropical spastic paraparesis;HTLV-1;HTLV-I-associated myelopathy;HAM;
28	Systemic amyloidosis;AL amyloidosis;
36	Epidermolysis bullosa;
38	Stevens-Johnson syndrome;SJS;Mucocutaneous ocular syndrome;
39	Toxic epidermal necrolysis;Toxic epidermal necrosis;TEN;
40	Takayasu arteritis;Aortitis syndrome;Pulseless disease;Aortitis syndrome;
41	Giant cell arteritis;Temporal arteritis;
42	Polyarteritis nodosa;PAN;
45	Eosinophilic granulomatosis with Polyangiitis;EGPA;Eosinophilic multiple vasculitis granulomatous disease;Allergic granulomatous angiitis;AGA;Churg-Strauss syndrome;CSS;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
49	Systemic lupus erythematosus;SLE;
50	Dermatomyositis;Polymyositis;
53	Sjogren syndrome;Sjögren syndrome;Syndrome Sjogren's;SS;Autoimmune exocrinopathy;
55	Relapsing polychondritis;
56	Behcet disease;Behçet disease;BD;
58	Hypertrophic cardiomyopathy;HCM;
60	Aplastic anemia;
61	Autoimmune hemolytic anemia;AIHA;
62	Paroxysmal nocturnal hemoglobinuria;PNH;
63	Idiopathic thrombocytopenic purpura;Primary immune thrombocytopenia;
64	Thrombotic thrombocytopenic purpura;TTP;
65	Primary immunodeficiency;
90	Retinitis pigmentosa;
93	Primary biliary cholangitis;Primary biliary cirrhosis;PBC;
95	Autoimmune hepatitis;
97	Ulcerative colitis;
107	Juvenile idiopathic arthritis;JIA;
113	Muscular dystrophy;
162	Pemphigoid;
164	Oculocutaneous albinism;
222	Primary nephrotic syndrome;
226	Interstitial cystitis with Hunners ulcer;Interstitial cystitis;
228	Bronchiolitis obliterans;Obliterating bronchiolitis;
234	Peroxisomal disease (except Adrenoleukodystrophy);Peroxisomal disease;Peroxisomal disorder;Peroxisome biogenesis disorder;
269	Pyogenic arthritis;Pyoderma gangrenosum;Acne syndrome;PAPA syndrome;
274	Osteogenesis Imperfecta;
283	Acquired pure red cell aplasia;Pure red cell aplasia;
284	Diamond-Blackfan anemia;
285	Fanconi anemia;
302	Leber hereditary optic neuropathy;
326	Osteopetrosis;

C-type lectin receptor signaling pathway 💬

[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬

Name	Full Name
PPP3CA	protein phosphatase 3 catalytic subunit alpha
PPP3CB	protein phosphatase 3 catalytic subunit beta
PPP3CC	protein phosphatase 3 catalytic subunit gamma
PPP3R1	protein phosphatase 3 regulatory subunit B, alpha
PPP3R2	protein phosphatase 3 regulatory subunit B, beta

Pimecrolimus 💬

Pimecrolimus

[1] 160 💬

C-type lectin receptor signaling pathway 💬

[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬

Name	Full Name
PPP3CA	protein phosphatase 3 catalytic subunit alpha
PPP3CB	protein phosphatase 3 catalytic subunit beta
PPP3CC	protein phosphatase 3 catalytic subunit gamma
PPP3R1	protein phosphatase 3 regulatory subunit B, alpha
PPP3R2	protein phosphatase 3 regulatory subunit B, beta

Tacrolimus 💬

Tacrolimus

[34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
6	Parkinson disease;Disease Parkinson's;
11	Myasthenia gravis;MG;
13	Multiple sclerosis/Neuromyelitis optica;
36	Epidermolysis bullosa;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
49	Systemic lupus erythematosus;SLE;
50	Dermatomyositis;Polymyositis;
51	Scleroderma;Systemic sclerosis;SSc;
53	Sjogren syndrome;Sjögren syndrome;Syndrome Sjogren's;SS;Autoimmune exocrinopathy;
56	Behcet disease;Behçet disease;BD;
60	Aplastic anemia;
61	Autoimmune hemolytic anemia;AIHA;
62	Paroxysmal nocturnal hemoglobinuria;PNH;
65	Primary immunodeficiency;
66	IgA nephropathy;IgA nephritis;Berger disease;IgA-IgG nephropathy;
85	Idiopathic interstitial pneumonia;IIPs;
95	Autoimmune hepatitis;
96	Crohn disease;Terminal ileitis;
97	Ulcerative colitis;
113	Muscular dystrophy;
151	Rasmussen encephalitis;
158	Tuberous sclerosis;Tuberous sclerosis complex;
164	Oculocutaneous albinism;
222	Primary nephrotic syndrome;
224	Purpura nephritis;
226	Interstitial cystitis with Hunners ulcer;Interstitial cystitis;
227	Osler disease;Hereditary hemorrhagic telangiectasia;Osler-Weber-Rendu disease;
228	Bronchiolitis obliterans;Obliterating bronchiolitis;
283	Acquired pure red cell aplasia;Pure red cell aplasia;
284	Diamond-Blackfan anemia;
285	Fanconi anemia;
286	Hereditary sideroblastic anemia;Congenital sideroblastic anemia;Sideroblastic anemia;
299	Cystic fibrosis;

C-type lectin receptor signaling pathway 💬

[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬

Name	Full Name
PPP3CA	protein phosphatase 3 catalytic subunit alpha
PPP3CB	protein phosphatase 3 catalytic subunit beta
PPP3CC	protein phosphatase 3 catalytic subunit gamma
PPP3R1	protein phosphatase 3 regulatory subunit B, alpha
PPP3R2	protein phosphatase 3 regulatory subunit B, beta

Tacrolimus 💬

Tacrolimus

[34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
6	Parkinson disease;Disease Parkinson's;
11	Myasthenia gravis;MG;
13	Multiple sclerosis/Neuromyelitis optica;
36	Epidermolysis bullosa;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
49	Systemic lupus erythematosus;SLE;
50	Dermatomyositis;Polymyositis;
51	Scleroderma;Systemic sclerosis;SSc;
53	Sjogren syndrome;Sjögren syndrome;Syndrome Sjogren's;SS;Autoimmune exocrinopathy;
56	Behcet disease;Behçet disease;BD;
60	Aplastic anemia;
61	Autoimmune hemolytic anemia;AIHA;
62	Paroxysmal nocturnal hemoglobinuria;PNH;
65	Primary immunodeficiency;
66	IgA nephropathy;IgA nephritis;Berger disease;IgA-IgG nephropathy;
85	Idiopathic interstitial pneumonia;IIPs;
95	Autoimmune hepatitis;
96	Crohn disease;Terminal ileitis;
97	Ulcerative colitis;
113	Muscular dystrophy;
151	Rasmussen encephalitis;
158	Tuberous sclerosis;Tuberous sclerosis complex;
164	Oculocutaneous albinism;
222	Primary nephrotic syndrome;
224	Purpura nephritis;
226	Interstitial cystitis with Hunners ulcer;Interstitial cystitis;
227	Osler disease;Hereditary hemorrhagic telangiectasia;Osler-Weber-Rendu disease;
228	Bronchiolitis obliterans;Obliterating bronchiolitis;
283	Acquired pure red cell aplasia;Pure red cell aplasia;
284	Diamond-Blackfan anemia;
285	Fanconi anemia;
286	Hereditary sideroblastic anemia;Congenital sideroblastic anemia;Sideroblastic anemia;
299	Cystic fibrosis;

C-type lectin receptor signaling pathway 💬

[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬

Name	Full Name
PPP3CA	protein phosphatase 3 catalytic subunit alpha
PPP3CB	protein phosphatase 3 catalytic subunit beta
PPP3CC	protein phosphatase 3 catalytic subunit gamma
PPP3R1	protein phosphatase 3 regulatory subunit B, alpha
PPP3R2	protein phosphatase 3 regulatory subunit B, beta

Voclosporin 💬

Voclosporin

[2] 49, 222 💬

C-type lectin receptor signaling pathway 💬

[1] PRKCD 💬

Sotrastaurin 💬

Sotrastaurin

[1] 97 💬

C-type lectin receptor signaling pathway 💬

[1] PTGS2 💬

Aceclofenac 💬

Aceclofenac

[1] 46 💬

C-type lectin receptor signaling pathway 💬

[1] PTGS2 💬

Acetaminophen 💬

Acetaminophen

[15] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬

Disease ID	Name
3	Spinal muscular atrophy;Myelopathic muscular atrophy;
6	Parkinson disease;Disease Parkinson's;
11	Myasthenia gravis;MG;
13	Multiple sclerosis/Neuromyelitis optica;
34	Neurofibromatosis;
35	Pemphigus;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
49	Systemic lupus erythematosus;SLE;
51	Scleroderma;Systemic sclerosis;SSc;
70	Spinal stenosis;Extensive spinal canal stenosis;
86	Pulmonary arterial hypertension;PAH;
222	Primary nephrotic syndrome;
256	Muscle glycogenosis;Muscular glycogenosis;Muscle glycogen storage disease;Muscular glycogen storage disease;
271	Ankylosing spondylitis;Spondylarthritis ankylopoietica;
337	Homocystinuria;

C-type lectin receptor signaling pathway 💬

[1] PTGS2 💬

Aspirin 💬

Acetylsalicylic acid

[14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬

Disease ID	Name
13	Multiple sclerosis/Neuromyelitis optica;
22	Moyamoya disease;Occlusive disease in circle of Willis;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
49	Systemic lupus erythematosus;SLE;
51	Scleroderma;Systemic sclerosis;SSc;
58	Hypertrophic cardiomyopathy;HCM;
64	Thrombotic thrombocytopenic purpura;TTP;
86	Pulmonary arterial hypertension;PAH;
97	Ulcerative colitis;
113	Muscular dystrophy;
158	Tuberous sclerosis;Tuberous sclerosis complex;
210	Single Ventricle;SV;Single ventricle heart defect;Univentricular heart;UVH;Single ventricular circulation syndrome;
231	Alpha-1-antitrypsin deficiency;AATD;
251	Urea cycle disorder;

C-type lectin receptor signaling pathway 💬

[1] PTGS2 💬

Celecoxib 💬

Celecoxib

[10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
3	Spinal muscular atrophy;Myelopathic muscular atrophy;
34	Neurofibromatosis;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
70	Spinal stenosis;Extensive spinal canal stenosis;
89	Lymphangioleiomyomatosis;LAM;
107	Juvenile idiopathic arthritis;JIA;
161	Familial benign chronic pemphigus;Benign familial pemphigus;Hailey-Hailey disease;
171	Wilson disease;WD;
271	Ankylosing spondylitis;Spondylarthritis ankylopoietica;

C-type lectin receptor signaling pathway 💬

[1] PTGS2 💬

Diclofenac 💬

Diclofenac

[5] 13, 34, 46, 78, 271 💬

Disease ID	Name
13	Multiple sclerosis/Neuromyelitis optica;
34	Neurofibromatosis;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
78	Hypopituitarism;Anterior pituitary hypothyroidism;
271	Ankylosing spondylitis;Spondylarthritis ankylopoietica;

C-type lectin receptor signaling pathway 💬

[1] PTGS2 💬

Diflunisal 💬

Diflunisal

[1] 28 💬

C-type lectin receptor signaling pathway 💬

[1] PTGS2 💬

Etodolac 💬

Etodolac

[1] 46 💬

C-type lectin receptor signaling pathway 💬

[1] PTGS2 💬

Etoricoxib 💬

Etoricoxib

[2] 46, 271 💬

C-type lectin receptor signaling pathway 💬

[1] PTGS2 💬

Flurbiprofen 💬

Flurbiprofen

[3] 13, 21, 46 💬

C-type lectin receptor signaling pathway 💬

[1] PTGS2 💬

Ibuprofen 💬

Ibuprofen

[7] 13, 46, 65, 107, 113, 271, 299 💬

Disease ID	Name
13	Multiple sclerosis/Neuromyelitis optica;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
65	Primary immunodeficiency;
107	Juvenile idiopathic arthritis;JIA;
113	Muscular dystrophy;
271	Ankylosing spondylitis;Spondylarthritis ankylopoietica;
299	Cystic fibrosis;

C-type lectin receptor signaling pathway 💬

[1] PTGS2 💬

Indomethacin 💬

Indomethacin

[3] 225, 271, 298 💬

Disease ID	Name
225	Congenital nephrogenic diabetes insipidus;Hereditary nephrogenic diabetes insipidus;Nephrogenic diabetes insipidus;
271	Ankylosing spondylitis;Spondylarthritis ankylopoietica;
298	Hereditary pancreatitis;Chronic pancreatitis;

C-type lectin receptor signaling pathway 💬

[1] PTGS2 💬

Ketoprofen 💬

Ketoprofen

[1] 46 💬

C-type lectin receptor signaling pathway 💬

[1] PTGS2 💬

Ketorolac 💬

Ketorolac

[2] 70, 226 💬

C-type lectin receptor signaling pathway 💬

[1] PTGS2 💬

Loxoprofen 💬

Loxoprofen

[2] 46, 271 💬

C-type lectin receptor signaling pathway 💬

[1] PTGS2 💬

Lumiracoxib 💬

Lumiracoxib

[1] 46 💬

C-type lectin receptor signaling pathway 💬

[1] PTGS2 💬

Meloxicam 💬

Meloxicam

[4] 46, 49, 271, 296 💬

Disease ID	Name
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
49	Systemic lupus erythematosus;SLE;
271	Ankylosing spondylitis;Spondylarthritis ankylopoietica;
296	Biliary atresia;

C-type lectin receptor signaling pathway 💬

[1] PTGS2 💬

Naproxen 💬

Naproxen

[4] 13, 46, 107, 271 💬

Disease ID	Name
13	Multiple sclerosis/Neuromyelitis optica;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
107	Juvenile idiopathic arthritis;JIA;
271	Ankylosing spondylitis;Spondylarthritis ankylopoietica;

C-type lectin receptor signaling pathway 💬

[1] PTGS2 💬

Nimesulide 💬

Nimesulide

[1] 46 💬

C-type lectin receptor signaling pathway 💬

[1] PTGS2 💬

Parecoxib 💬

Parecoxib

[2] 46, 271 💬

C-type lectin receptor signaling pathway 💬

[1] PTGS2 💬

Rofecoxib 💬

Rofecoxib

[1] 46 💬

C-type lectin receptor signaling pathway 💬

[1] PTGS2 💬

Salsalate 💬

Salsalate

[1] 5 💬

C-type lectin receptor signaling pathway 💬

[1] PTGS2 💬

Sulindac 💬

Sulindac

[1] 206 💬

C-type lectin receptor signaling pathway 💬

[1] PTGS2 💬

Tolfenamic acid 💬

Tolfenamic acid

[1] 5 💬

C-type lectin receptor signaling pathway 💬

[1] PTGS2 💬

Valdecoxib 💬

Valdecoxib

[1] 46 💬

C-type lectin receptor signaling pathway 💬

[1] RAF1 💬

Sorafenib 💬

Sorafenib

[2] 34, 86 💬

C-type lectin receptor signaling pathway 💬

[1] RELA 💬

Edasalonexent 💬

Edasalonexent

[1] 113 💬

C-type lectin receptor signaling pathway 💬

[1] SRC 💬

Bosutinib 💬

Bosutinib

[2] 2 , 67 💬

C-type lectin receptor signaling pathway 💬

[1] SRC 💬

Dasatinib 💬

Dasatinib

[2] 51, 85 💬

C-type lectin receptor signaling pathway 💬

[1] SRC 💬

Dasatinib 💬

Dasatinib

[2] 51, 85 💬

C-type lectin receptor signaling pathway 💬

[1] SRC 💬

Saracatinib 💬

Saracatinib

[3] 6 , 89, 272 💬

C-type lectin receptor signaling pathway 💬

[1] SYK 💬

Fostamatinib 💬

Fostamatinib

[4] 46, 49, 61, 66 💬

Disease ID	Name
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
49	Systemic lupus erythematosus;SLE;
61	Autoimmune hemolytic anemia;AIHA;
66	IgA nephropathy;IgA nephritis;Berger disease;IgA-IgG nephropathy;

C-type lectin receptor signaling pathway 💬

[1] TNF 💬

Adalimumab 💬

Name

Other Names

Adalimumab

Adalimumab (USAN/INN)
Adalimumab (genetical recombination) (JAN)
Adalimumab (genetical recombination) [Adalimumab biosimilar 1] (JAN)
Adalimumab (genetical recombination) [Adalimumab biosimilar 2] (JAN)
Adalimumab (genetical recombination) [Adalimumab biosimilar 3] (JAN)
Adalimumab-adaz
Adalimumab-adbm
Adalimumab-afzb
Adalimumab-atto
Adalimumab-bwwd
Adalimumab-fkjp
Humira (TN)
Abrilada (TN)
Amjevita (TN)
Cyltezo (TN)
Hadlima (TN)
Hyrimoz (TN)

Adalimumab

[17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬

Disease ID	Name
19	Lysosomal storage disease;Lysosomal disease;
37	Generalised pustular psoriasis;Pustular psoriasis;
40	Takayasu arteritis;Aortitis syndrome;Pulseless disease;Aortitis syndrome;
41	Giant cell arteritis;Temporal arteritis;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
56	Behcet disease;Behçet disease;BD;
84	Sarcoidosis;
96	Crohn disease;Terminal ileitis;
97	Ulcerative colitis;
107	Juvenile idiopathic arthritis;JIA;
160	Congenital ichthyosis;
164	Oculocutaneous albinism;
222	Primary nephrotic syndrome;
226	Interstitial cystitis with Hunners ulcer;Interstitial cystitis;
269	Pyogenic arthritis;Pyoderma gangrenosum;Acne syndrome;PAPA syndrome;
270	Chronic recurrent multifocal osteomyelitis;
271	Ankylosing spondylitis;Spondylarthritis ankylopoietica;

C-type lectin receptor signaling pathway 💬

[1] TNF 💬

Certolizumab pegol 💬

Certolizumab pegol

[8] 37, 46, 49, 96, 97, 107, 226, 271 💬

Disease ID	Name
37	Generalised pustular psoriasis;Pustular psoriasis;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
49	Systemic lupus erythematosus;SLE;
96	Crohn disease;Terminal ileitis;
97	Ulcerative colitis;
107	Juvenile idiopathic arthritis;JIA;
226	Interstitial cystitis with Hunners ulcer;Interstitial cystitis;
271	Ankylosing spondylitis;Spondylarthritis ankylopoietica;

C-type lectin receptor signaling pathway 💬

[1] TNF 💬

Etanercept 💬

Name	Other Names
Etanercept	Etanercept (USAN/INN) Etanercept (genetical recombination) (JAN) Etanercept (genetical recombination) [Etanercept biosimilar 1] (JAN) Etanercept (genetical recombination) [Etanercept biosimilar 2] (JAN) Enbrel (TN)

Etanercept

[16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬

Disease ID	Name
15	Inclusion body myositis;
28	Systemic amyloidosis;AL amyloidosis;
35	Pemphigus;
38	Stevens-Johnson syndrome;SJS;Mucocutaneous ocular syndrome;
39	Toxic epidermal necrolysis;Toxic epidermal necrosis;TEN;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
50	Dermatomyositis;Polymyositis;
53	Sjogren syndrome;Sjögren syndrome;Syndrome Sjogren's;SS;Autoimmune exocrinopathy;
56	Behcet disease;Behçet disease;BD;
60	Aplastic anemia;
85	Idiopathic interstitial pneumonia;IIPs;
107	Juvenile idiopathic arthritis;JIA;
228	Bronchiolitis obliterans;Obliterating bronchiolitis;
270	Chronic recurrent multifocal osteomyelitis;
271	Ankylosing spondylitis;Spondylarthritis ankylopoietica;
285	Fanconi anemia;

C-type lectin receptor signaling pathway 💬

[1] TNF 💬

Golimumab 💬

Golimumab

[8] 46, 56, 84, 96, 97, 107, 270, 271 💬

Disease ID	Name
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
56	Behcet disease;Behçet disease;BD;
84	Sarcoidosis;
96	Crohn disease;Terminal ileitis;
97	Ulcerative colitis;
107	Juvenile idiopathic arthritis;JIA;
270	Chronic recurrent multifocal osteomyelitis;
271	Ankylosing spondylitis;Spondylarthritis ankylopoietica;

C-type lectin receptor signaling pathway 💬

[1] TNF 💬

Infliximab 💬

Name	Other Names
Infliximab	Infliximab (USAN/INN) Infliximab (genetical recombination) (JAN) Infliximab (genetical recombination) [Infliximab biosimilar 1] (JAN) Infliximab (genetical recombination) [Infliximab biosimilar 2] (JAN) Infliximab (genetical recombination) [Infliximab biosimilar 3] (JAN) Infliximab-dyyb Infliximab-abda Infliximab-axxq Remicade (TN) Inflectra (TN) Renflexis (TN) Avsola (TN)

Infliximab

[27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬

Disease ID	Name
35	Pemphigus;
37	Generalised pustular psoriasis;Pustular psoriasis;
38	Stevens-Johnson syndrome;SJS;Mucocutaneous ocular syndrome;
39	Toxic epidermal necrolysis;Toxic epidermal necrosis;TEN;
40	Takayasu arteritis;Aortitis syndrome;Pulseless disease;Aortitis syndrome;
41	Giant cell arteritis;Temporal arteritis;
42	Polyarteritis nodosa;PAN;
43	Microscopic polyangiitis;MPA;
45	Eosinophilic granulomatosis with Polyangiitis;EGPA;Eosinophilic multiple vasculitis granulomatous disease;Allergic granulomatous angiitis;AGA;Churg-Strauss syndrome;CSS;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
49	Systemic lupus erythematosus;SLE;
50	Dermatomyositis;Polymyositis;
55	Relapsing polychondritis;
56	Behcet disease;Behçet disease;BD;
65	Primary immunodeficiency;
84	Sarcoidosis;
85	Idiopathic interstitial pneumonia;IIPs;
95	Autoimmune hepatitis;
96	Crohn disease;Terminal ileitis;
97	Ulcerative colitis;
98	Eosinophilic gastrointestinal disease;Eosinophilic gastroenteritis;Eosinophilic esophagitis;Eosinophilic colitis;Eosinophilic gastro-intestinal disorder;EGID;
107	Juvenile idiopathic arthritis;JIA;
162	Pemphigoid;
164	Oculocutaneous albinism;
269	Pyogenic arthritis;Pyoderma gangrenosum;Acne syndrome;PAPA syndrome;
270	Chronic recurrent multifocal osteomyelitis;
271	Ankylosing spondylitis;Spondylarthritis ankylopoietica;

C-type lectin receptor signaling pathway 💬

[1] TNF 💬

Lenalidomide 💬

Lenalidomide

[8] 16, 26, 28, 34, 49, 284, 300, 331 💬

Disease ID	Name
16	Crow-Fukase syndrome;POEMS syndrome;
26	HTLV-1-associated myelopathy;Tropical spastic paraparesis;HTLV-1;HTLV-I-associated myelopathy;HAM;
28	Systemic amyloidosis;AL amyloidosis;
34	Neurofibromatosis;
49	Systemic lupus erythematosus;SLE;
284	Diamond-Blackfan anemia;
300	IgG4-related disease;
331	Idiopathic multicentric castleman disease;iMCD;Castleman disease;

C-type lectin receptor signaling pathway 💬

[1] TNF 💬

Ozoralizumab 💬

Ozoralizumab

[1] 46 💬

C-type lectin receptor signaling pathway 💬

[1] TNF 💬

Pegsunercept 💬

Pegsunercept

[1] 46 💬

C-type lectin receptor signaling pathway 💬

[1] TNF 💬

Thalidomide 💬

Thalidomide

[20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
16	Crow-Fukase syndrome;POEMS syndrome;
20	Adrenoleukodystrophy;ALD;
28	Systemic amyloidosis;AL amyloidosis;
49	Systemic lupus erythematosus;SLE;
51	Scleroderma;Systemic sclerosis;SSc;
53	Sjogren syndrome;Sjögren syndrome;Syndrome Sjogren's;SS;Autoimmune exocrinopathy;
56	Behcet disease;Behçet disease;BD;
65	Primary immunodeficiency;
84	Sarcoidosis;
85	Idiopathic interstitial pneumonia;IIPs;
94	Primary sclerosing cholangitis;PSC;
96	Crohn disease;Terminal ileitis;
97	Ulcerative colitis;
227	Osler disease;Hereditary hemorrhagic telangiectasia;Osler-Weber-Rendu disease;
271	Ankylosing spondylitis;Spondylarthritis ankylopoietica;
280	Huge arteriovenous malformation with cervicofacial or limb lesion;Huge arteriovenous malformation;Arteriovenous malformation;
298	Hereditary pancreatitis;Chronic pancreatitis;
300	IgG4-related disease;
331	Idiopathic multicentric castleman disease;iMCD;Castleman disease;