Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Taste transduction 💬
 [1] CACNA1C 💬 Amlodipine 💬 Amlodipine [4] 13, 51, 67, 298 💬
2 Taste transduction 💬
 [1] CACNA1C 💬 Cilnidipine 💬 Cilnidipine [1] 67 💬
3 Taste transduction 💬
 [1] CACNA1C 💬 Diltiazem 💬 Diltiazem [3] 51, 58, 86 💬
4 Taste transduction 💬
 [1] CACNA1C 💬 Isradipine 💬 Isradipine [1]  6  💬
5 Taste transduction 💬
 [1] CACNA1C 💬 Nicardipine 💬 Nicardipine [2] 70, 86 💬
6 Taste transduction 💬
 [1] CACNA1C 💬 Nifedipine 💬 Nifedipine [2] 50, 81 💬
7 Taste transduction 💬
 [1] CACNA1C 💬 Nilvadipine 💬 Nilvadipine [1] 90 💬
8 Taste transduction 💬
 [1] CACNA1C 💬 Perhexiline 💬 Perhexiline [2] 58, 272 💬
9 Taste transduction 💬
 [1] CACNA1C 💬 Verapamil 💬 Verapamil [4] 58, 96, 140, 167 💬
10 Taste transduction 💬
 [2] CACNA1C, CHRM3 💬 Propiverine 💬 Propiverine [1] 226 💬
11 Taste transduction 💬
 [10] CACNA1C, GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, SCN2A, SCN3A, SCN9A 💬 Topiramate 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
12 Taste transduction 💬
 [1] CHRM3 💬 Atropine 💬 Atropine [2]  2 , 299 💬
13 Taste transduction 💬
 [1] CHRM3 💬 Blarcamesine 💬 Blarcamesine [1] 156 💬
14 Taste transduction 💬
 [1] CHRM3 💬 Cevimeline 💬 Cevimeline [1] 53 💬
15 Taste transduction 💬
 [1] CHRM3 💬 Chlorpromazine 💬 Chlorpromazine [1] 254 💬
16 Taste transduction 💬
 [1] CHRM3 💬 Darifenacin 💬 Darifenacin [2]  6 , 13 💬
17 Taste transduction 💬
 [1] CHRM3 💬 Fesoterodine 💬 Fesoterodine [1]  6  💬
18 Taste transduction 💬
 [1] CHRM3 💬 Oxybutynin 💬 Oxybutynin [3]  6 , 13, 53 💬
19 Taste transduction 💬
 [1] CHRM3 💬 Pilocarpine 💬 Pilocarpine [3]  6 , 53, 299 💬
20 Taste transduction 💬
 [1] CHRM3 💬 Scopolamine 💬 Scopolamine [1]  2  💬
21 Taste transduction 💬
 [1] CHRM3 💬 Solifenacin 💬 Solifenacin [3]  6 , 13, 53 💬
22 Taste transduction 💬
 [1] CHRM3 💬 Tolterodine 💬 Tolterodine [2] 17, 53 💬
23 Taste transduction 💬
 [1] CHRM3 💬 Trihexyphenidyl 💬 Trihexyphenidyl [2]  5 ,  6  💬
24 Taste transduction 💬
 [1] CHRM3 💬 Tropicamide 💬 Tropicamide [1]  6  💬
25 Taste transduction 💬
 [2] GABBR1, GABBR2 💬 Arbaclofen 💬 Arbaclofen [2] 13, 206 💬
26 Taste transduction 💬
 [2] GABBR1, GABBR2 💬 Arbaclofen placarbil 💬 Arbaclofen Placarbil [1] 13 💬
27 Taste transduction 💬
 [2] GABBR1, GABBR2 💬 Baclofen 💬 Baclofen [8]  2 , 10, 13, 18, 65, 70, 149, 206 💬
28 Taste transduction 💬
 [2] GABBR1, GABBR2 💬 Valiloxybate 💬 Valiloxybate [1]  6  💬
29 Taste transduction 💬
 [1] GABRA1 💬 Etomidate 💬 Etomidate [1]  6  💬
30 Taste transduction 💬
 [6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 Alprazolam 💬 Alprazolam [2]  8 , 75 💬
31 Taste transduction 💬
 [6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 Brexanolone 💬 Brexanolone [1] 205 💬
32 Taste transduction 💬
 [6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 Clobazam 💬 Clobazam [2] 140, 144 💬
33 Taste transduction 💬
 [6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 Clonazepam 💬 Clonazepam [1]  6  💬
34 Taste transduction 💬
 [6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 Delorazepam 💬 Delorazepam [3]  6 , 46, 97 💬
35 Taste transduction 💬
 [6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 Diazepam 💬 Diazepam [3] 46, 155, 298 💬
36 Taste transduction 💬
 [6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 Eszopiclone 💬 Eszopiclone [3]  6 , 13, 46 💬
37 Taste transduction 💬
 [6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 Flumazenil 💬 Flumazenil [5]  6 , 13, 17, 18, 206 💬
38 Taste transduction 💬
 [6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 Gaboxadol 💬 Gaboxadol [2] 201, 206 💬
39 Taste transduction 💬
 [6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 Ganaxolone 💬 Ganaxolone [4] 145, 152, 158, 206 💬
40 Taste transduction 💬
 [6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 Lorazepam 💬 Lorazepam [1] 36 💬
41 Taste transduction 💬
 [6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 Midazolam 💬 Midazolam [12]  2 ,  3 ,  6 , 13, 21, 46, 70, 96, 97, 272, 298, 299 💬
42 Taste transduction 💬
 [6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 Propofol 💬 Propofol [9]  6 , 21, 22, 34, 46, 70, 75, 98, 296 💬
43 Taste transduction 💬
 [6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 Zolpidem 💬 Zolpidem [3]  5 ,  6 , 46 💬
44 Taste transduction 💬
 [6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 Zopiclone 💬 Zopiclone [1]  6  💬
45 Taste transduction 💬
 [1] HTR1A 💬 Aripiprazole 💬 Aripiprazole [2]  6 , 206 💬
46 Taste transduction 💬
 [1] HTR1A 💬 Buspirone 💬 Buspirone [2]  6 , 51 💬
47 Taste transduction 💬
 [1] HTR1A 💬 Cariprazine 💬 Cariprazine [1] 21 💬
48 Taste transduction 💬
 [1] HTR1A 💬 Pardoprunox 💬 Pardoprunox [1]  6  💬
49 Taste transduction 💬
 [6] HTR1A, HTR3A, HTR3B, HTR3C, HTR3D, HTR3E 💬 Vortioxetine 💬 Vortioxetine [1]  6  💬
50 Taste transduction 💬
 [2] HTR1B, HTR1D 💬 Zolmitriptan 💬 Zolmitriptan [1]  6  💬
51 Taste transduction 💬
 [1] HTR1D 💬 Fenfluramine 💬 Fenfluramine [4] 140, 144, 145, 149 💬
52 Taste transduction 💬
 [1] HTR3A 💬 Cisapride 💬 Cisapride [1] 13 💬
53 Taste transduction 💬
 [1] HTR3A 💬 Cisapride 💬 Cisapride [1] 13 💬
54 Taste transduction 💬
 [5] HTR3A, HTR3B, HTR3C, HTR3D, HTR3E 💬 Clozapine 💬 Clozapine [1]  6  💬
55 Taste transduction 💬
 [5] HTR3A, HTR3B, HTR3C, HTR3D, HTR3E 💬 Dolasetron 💬 Dolasetron [1] 46 💬
56 Taste transduction 💬
 [5] HTR3A, HTR3B, HTR3C, HTR3D, HTR3E 💬 Ondansetron 💬 Ondansetron [3]  6 , 97, 107 💬
57 Taste transduction 💬
 [1] P2RX3 💬 Gefapixant 💬 Gefapixant [2] 85, 226 💬
58 Taste transduction 💬
 [3] PDE1A, PDE1B, PDE1C 💬 Aminophylline 💬 Aminophylline [1] 63 💬
59 Taste transduction 💬
 [3] PDE1A, PDE1B, PDE1C 💬 Bucladesine 💬 Bucladesine [1] 246 💬
60 Taste transduction 💬
 [3] PDE1A, PDE1B, PDE1C 💬 Flavoxate 💬 Flavoxate [1] 226 💬
61 Taste transduction 💬
 [3] PDE1A, PDE1B, PDE1C 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
62 Taste transduction 💬
 [3] PDE1A, PDE1B, PDE1C 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
63 Taste transduction 💬
 [1] PDE1B 💬 Caffeine 💬 Caffeine [8]  2 ,  6 , 21, 46, 78, 96, 97, 265 💬
64 Taste transduction 💬
 [1] PDE1B 💬 Caffeine hydrate 💬 Caffeine [8]  2 ,  6 , 21, 46, 78, 96, 97, 265 💬
65 Taste transduction 💬
 [3] SCN2A, SCN3A, SCN9A 💬 Amiodarone 💬 Amiodarone [2] 28, 127 💬
66 Taste transduction 💬
 [3] SCN2A, SCN3A, SCN9A 💬 Bupivacaine 💬 Bupivacaine [8] 46, 51, 53, 70, 96, 168, 226, 298 💬
67 Taste transduction 💬
 [3] SCN2A, SCN3A, SCN9A 💬 Carbamazepine 💬 Carbamazepine [3]  6 , 13, 231 💬
68 Taste transduction 💬
 [3] SCN2A, SCN3A, SCN9A 💬 Cifenline 💬 Cibenzoline [1] 58 💬
69 Taste transduction 💬
 [3] SCN2A, SCN3A, SCN9A 💬 Eleclazine 💬 Eleclazine [1] 58 💬
70 Taste transduction 💬
 [3] SCN2A, SCN3A, SCN9A 💬 Flecainide 💬 Flecainide [1]  6  💬
71 Taste transduction 💬
 [3] SCN2A, SCN3A, SCN9A 💬 Lamotrigine 💬 Lamotrigine [5] 13, 34, 38, 114, 144 💬
72 Taste transduction 💬
 [3] SCN2A, SCN3A, SCN9A 💬 Levobupivacaine 💬 Levobupivacaine [1] 46 💬
73 Taste transduction 💬
 [3] SCN2A, SCN3A, SCN9A 💬 Lidocaine 💬 Lidocaine [13]  6 , 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
74 Taste transduction 💬
 [3] SCN2A, SCN3A, SCN9A 💬 Lidocaine hydrochloride monohydrate 💬 Lidocaine [13]  6 , 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
75 Taste transduction 💬
 [3] SCN2A, SCN3A, SCN9A 💬 Mexiletine 💬 Mexiletine [5]  1 ,  2 , 10, 113, 114 💬
76 Taste transduction 💬
 [3] SCN2A, SCN3A, SCN9A 💬 Oxcarbazepine 💬 Oxcarbazepine [1] 13 💬
77 Taste transduction 💬
 [3] SCN2A, SCN3A, SCN9A 💬 Oxybuprocaine 💬 Oxybuprocaine [1]  6  💬
78 Taste transduction 💬
 [3] SCN2A, SCN3A, SCN9A 💬 Phenytoin 💬 Phenytoin [1] 13 💬
79 Taste transduction 💬
 [3] SCN2A, SCN3A, SCN9A 💬 Quinidine 💬 Quinidine [3]  2 ,  8 , 13 💬
80 Taste transduction 💬
 [3] SCN2A, SCN3A, SCN9A 💬 Ropivacaine 💬 Ropivacaine [4] 22, 36, 46, 70 💬
81 Taste transduction 💬
 [3] SCN2A, SCN3A, SCN9A 💬 Rufinamide 💬 Rufinamide [1] 144 💬
82 Taste transduction 💬
 [3] SCN2A, SCN3A, SCN9A 💬 Zonisamide 💬 Zonisamide [1]  6  💬
83 Taste transduction 💬
 [2] SCN3A, SCN9A 💬 Lacosamide 💬 Lacosamide [4]  2 , 46, 149, 298 💬
84 Taste transduction 💬
 [3] SCNN1A, SCNN1B, SCNN1G 💬 Amiloride 💬 Amiloride [4] 13, 67, 225, 299 💬
85 Taste transduction 💬
 [2] TAS1R2, TAS1R3 💬 Aspartame 💬 Aspartame [4]  6 , 13, 67, 86 💬