Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Inflammatory mediator regulation of TRP channels 💬
 [1] HRH1 💬 Cetirizine 💬 Cetirizine [4] 13, 28, 35, 300 💬
2 Inflammatory mediator regulation of TRP channels 💬
 [1] HRH1 💬 Chlorphenamine 💬 Chlorpheniramine [1] 14 💬
3 Inflammatory mediator regulation of TRP channels 💬
 [1] HRH1 💬 Clemastine 💬 Clemastine [1] 13 💬
4 Inflammatory mediator regulation of TRP channels 💬
 [1] HRH1 💬 Desloratadine 💬 Desloratadine [1] 13 💬
5 Inflammatory mediator regulation of TRP channels 💬
 [1] HRH1 💬 Dexchlorpheniramine 💬 Dexchlorpheniramine [2] 13, 49 💬
6 Inflammatory mediator regulation of TRP channels 💬
 [1] HRH1 💬 Diphenhydramine 💬 Diphenhydramine [8] 11, 13, 49, 51, 70, 86, 222, 256 💬
7 Inflammatory mediator regulation of TRP channels 💬
 [1] HRH1 💬 Doxepin 💬 Doxepin [1]  6  💬
8 Inflammatory mediator regulation of TRP channels 💬
 [1] HRH1 💬 Fexofenadine 💬 Fexofenadine [2] 13, 46 💬
9 Inflammatory mediator regulation of TRP channels 💬
 [1] HRH1 💬 Levocetirizine 💬 Levocetirizine [1] 61 💬
10 Inflammatory mediator regulation of TRP channels 💬
 [1] HRH1 💬 Loratadine 💬 Loratadine [4] 13, 46, 89, 98 💬
11 Inflammatory mediator regulation of TRP channels 💬
 [1] HRH1 💬 Promethazine 💬 Promethazine [1] 96 💬
12 Inflammatory mediator regulation of TRP channels 💬
 [1] HRH1 💬 Rupatadine 💬 Rupatadine [1] 46 💬
13 Inflammatory mediator regulation of TRP channels 💬
 [4] HRH1, HTR2A, HTR2B, HTR2C 💬 Chlorpromazine 💬 Chlorpromazine [1] 254 💬
14 Inflammatory mediator regulation of TRP channels 💬
 [4] HRH1, HTR2A, HTR2B, HTR2C 💬 Olanzapine 💬 Olanzapine [2]  2 ,  8  💬
15 Inflammatory mediator regulation of TRP channels 💬
 [1] HTR2A 💬 Aripiprazole 💬 Aripiprazole [2]  6 , 206 💬
16 Inflammatory mediator regulation of TRP channels 💬
 [1] HTR2A 💬 Cariprazine 💬 Cariprazine [1] 21 💬
17 Inflammatory mediator regulation of TRP channels 💬
 [1] HTR2A 💬 Cisapride 💬 Cisapride [1] 13 💬
18 Inflammatory mediator regulation of TRP channels 💬
 [1] HTR2A 💬 Cisapride 💬 Cisapride [1] 13 💬
19 Inflammatory mediator regulation of TRP channels 💬
 [1] HTR2A 💬 Nelotanserin 💬 Nelotanserin [1]  6  💬
20 Inflammatory mediator regulation of TRP channels 💬
 [1] HTR2A 💬 Quetiapine 💬 Quetiapine [2]  6 , 13 💬
21 Inflammatory mediator regulation of TRP channels 💬
 [1] HTR2A 💬 Risperidone 💬 Risperidone [5]  8 , 156, 179, 187, 206 💬
22 Inflammatory mediator regulation of TRP channels 💬
 [3] HTR2A, HTR2B, HTR2C 💬 Iloperidone 💬 Iloperidone [1]  6  💬
23 Inflammatory mediator regulation of TRP channels 💬
 [3] HTR2A, HTR2B, HTR2C 💬 Trazodone 💬 Trazodone [1]  2  💬
24 Inflammatory mediator regulation of TRP channels 💬
 [2] HTR2A, HTR2C 💬 Clozapine 💬 Clozapine [1]  6  💬
25 Inflammatory mediator regulation of TRP channels 💬
 [2] HTR2A, HTR2C 💬 Fenfluramine 💬 Fenfluramine [4] 140, 144, 145, 149 💬
26 Inflammatory mediator regulation of TRP channels 💬
 [1] HTR2C 💬 Agomelatine 💬 Agomelatine [1]  6  💬
27 Inflammatory mediator regulation of TRP channels 💬
 [1] IL1B 💬 Canakinumab 💬 Canakinumab [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
28 Inflammatory mediator regulation of TRP channels 💬
 [1] IL1B 💬 Gevokizumab 💬 Gevokizumab [4] 41, 50, 56, 269 💬
29 Inflammatory mediator regulation of TRP channels 💬
 [1] IL1B 💬 Pirfenidone 💬 Pirfenidone [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
30 Inflammatory mediator regulation of TRP channels 💬
 [1] IL1B 💬 Rilonacept 💬 Rilonacept [4] 51, 106, 107, 266 💬
31 Inflammatory mediator regulation of TRP channels 💬
 [1] IL1R1 💬 Anakinra 💬 Anakinra [18]  2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
32 Inflammatory mediator regulation of TRP channels 💬
 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 Losmapimod 💬 Losmapimod [2] 113, 222 💬
33 Inflammatory mediator regulation of TRP channels 💬
 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 Neflamapimod 💬 Neflamapimod [1]  8  💬
34 Inflammatory mediator regulation of TRP channels 💬
 [1] NGF 💬 Tanezumab 💬 Tanezumab [2] 226, 298 💬
35 Inflammatory mediator regulation of TRP channels 💬
 [1] PIK3CA 💬 Alpelisib 💬 Alpelisib [1] 138 💬
36 Inflammatory mediator regulation of TRP channels 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 Leniolisib 💬 Leniolisib [2] 53, 65 💬
37 Inflammatory mediator regulation of TRP channels 💬
 [1] PIK3CD 💬 Parsaclisib 💬 Parsaclisib [3] 35, 53, 61 💬
38 Inflammatory mediator regulation of TRP channels 💬
 [1] PRKCB 💬 Enzastaurin 💬 Enzastaurin [1] 168 💬
39 Inflammatory mediator regulation of TRP channels 💬
 [4] PRKCD, PRKCE, PRKCH, PRKCQ 💬 Sotrastaurin 💬 Sotrastaurin [1] 97 💬
40 Inflammatory mediator regulation of TRP channels 💬
 [2] PTGER2, PTGER4 💬 Misoprostol 💬 Misoprostol [3] 46, 70, 271 💬
41 Inflammatory mediator regulation of TRP channels 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
42 Inflammatory mediator regulation of TRP channels 💬
 [1] SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
43 Inflammatory mediator regulation of TRP channels 💬
 [1] SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
44 Inflammatory mediator regulation of TRP channels 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
45 Inflammatory mediator regulation of TRP channels 💬
 [1] TRPV1 💬 Capsaicin 💬 Capsaicin [3]  6 , 86, 226 💬