Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Regulation of actin cytoskeleton 💬
 [1] BRAF 💬 Dabrafenib 💬 Dabrafenib [1] 34 💬
2 Regulation of actin cytoskeleton 💬
 [3] BRAF, PDGFRB, RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
3 Regulation of actin cytoskeleton 💬
 [1] C5 💬 Crovalimab 💬 Crovalimab [2] 62, 109 💬
4 Regulation of actin cytoskeleton 💬
 [1] C5 💬 Eculizumab 💬 Eculizumab [7] 11, 13, 14, 61, 62, 109, 222 💬
5 Regulation of actin cytoskeleton 💬
 [1] C5 💬 Nomacopan 💬 Nomacopan [3] 62, 109, 162 💬
6 Regulation of actin cytoskeleton 💬
 [1] C5 💬 Pozelimab 💬 Pozelimab [2] 11, 62 💬
7 Regulation of actin cytoskeleton 💬
 [1] C5 💬 Ravulizumab 💬 Ravulizumab [7]  2 , 11, 13, 50, 62, 66, 109 💬
8 Regulation of actin cytoskeleton 💬
 [1] C5 💬 Vilobelimab 💬 Vilobelimab [3] 43, 44, 269 💬
9 Regulation of actin cytoskeleton 💬
 [1] C5 💬 Zilucoplan 💬 Zilucoplan [3]  2 , 11, 62 💬
10 Regulation of actin cytoskeleton 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Atropine 💬 Atropine [2]  2 , 299 💬
11 Regulation of actin cytoskeleton 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Blarcamesine 💬 Blarcamesine [1] 156 💬
12 Regulation of actin cytoskeleton 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Chlorpromazine 💬 Chlorpromazine [1] 254 💬
13 Regulation of actin cytoskeleton 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Oxybutynin 💬 Oxybutynin [3]  6 , 13, 53 💬
14 Regulation of actin cytoskeleton 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Propiverine 💬 Propiverine [1] 226 💬
15 Regulation of actin cytoskeleton 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Scopolamine 💬 Scopolamine [1]  2  💬
16 Regulation of actin cytoskeleton 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Trihexyphenidyl 💬 Trihexyphenidyl [2]  5 ,  6  💬
17 Regulation of actin cytoskeleton 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Tropicamide 💬 Tropicamide [1]  6  💬
18 Regulation of actin cytoskeleton 💬
 [2] CHRM2, CHRM3 💬 Fesoterodine 💬 Fesoterodine [1]  6  💬
19 Regulation of actin cytoskeleton 💬
 [2] CHRM2, CHRM3 💬 Pilocarpine 💬 Pilocarpine [3]  6 , 53, 299 💬
20 Regulation of actin cytoskeleton 💬
 [1] CHRM3 💬 Cevimeline 💬 Cevimeline [1] 53 💬
21 Regulation of actin cytoskeleton 💬
 [1] CHRM3 💬 Darifenacin 💬 Darifenacin [2]  6 , 13 💬
22 Regulation of actin cytoskeleton 💬
 [1] CHRM3 💬 Solifenacin 💬 Solifenacin [3]  6 , 13, 53 💬
23 Regulation of actin cytoskeleton 💬
 [1] CHRM3 💬 Tolterodine 💬 Tolterodine [2] 17, 53 💬
24 Regulation of actin cytoskeleton 💬
 [1] CXCR4 💬 Plerixafor 💬 Plerixafor [5] 19, 20, 65, 285, 299 💬
25 Regulation of actin cytoskeleton 💬
 [1] EGFR 💬 Cetuximab 💬 Cetuximab [2] 51, 86 💬
26 Regulation of actin cytoskeleton 💬
 [1] EGFR 💬 Erlotinib 💬 Erlotinib [1] 94 💬
27 Regulation of actin cytoskeleton 💬
 [1] EGFR 💬 Gefitinib 💬 Gefitinib [1] 75 💬
28 Regulation of actin cytoskeleton 💬
 [1] EGFR 💬 Icotinib 💬 Icotinib [1] 34 💬
29 Regulation of actin cytoskeleton 💬
 [1] EGFR 💬 Lapatinib 💬 Lapatinib [3] 34, 74, 75 💬
30 Regulation of actin cytoskeleton 💬
 [1] EGFR 💬 Neratinib 💬 Neratinib [1] 34 💬
31 Regulation of actin cytoskeleton 💬
 [1] EGFR 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
32 Regulation of actin cytoskeleton 💬
 [1] F2 💬 Dabigatran 💬 Dabigatran [5] 51, 75, 85, 91, 124 💬
33 Regulation of actin cytoskeleton 💬
 [1] F2 💬 Dabigatran etexilate 💬 Dabigatran etexilate [2] 51, 75 💬
34 Regulation of actin cytoskeleton 💬
 [1] F2 💬 Thrombomodulin alfa 💬 Thrombomodulin Alfa [1] 85 💬
35 Regulation of actin cytoskeleton 💬
 [1] FGF23 💬 Burosumab 💬 Burosumab [1] 238 💬
36 Regulation of actin cytoskeleton 💬
 [3] FGFR1, FGFR2, FGFR3 💬 Infigratinib 💬 Infigratinib [1] 276 💬
37 Regulation of actin cytoskeleton 💬
 [5] FGFR1, FGFR2, FGFR3, PDGFRA, PDGFRB 💬 Nintedanib 💬 Nintedanib [5] 51, 85, 89, 227, 228 💬
38 Regulation of actin cytoskeleton 💬
 [1] FGFR2 💬 Palifermin 💬 Palifermin [5] 13, 36, 38, 39, 65 💬
39 Regulation of actin cytoskeleton 💬
 [1] ITGA4 💬 Firategrast 💬 Firategrast [1] 13 💬
40 Regulation of actin cytoskeleton 💬
 [1] ITGA4 💬 Natalizumab 💬 Natalizumab [6] 13, 15, 25, 46, 63, 96 💬
41 Regulation of actin cytoskeleton 💬
 [2] ITGA4, ITGB7 💬 Abrilumab 💬 Abrilumab [2] 96, 97 💬
42 Regulation of actin cytoskeleton 💬
 [2] ITGA4, ITGB7 💬 Vedolizumab 💬 Vedolizumab [3] 94, 96, 97 💬
43 Regulation of actin cytoskeleton 💬
 [1] ITGAL 💬 Efalizumab 💬 Efalizumab [9] 11, 13, 37, 46, 49, 53, 61, 95, 96 💬
44 Regulation of actin cytoskeleton 💬
 [1] ITGB7 💬 Etrolizumab 💬 Etrolizumab [2] 96, 97 💬
45 Regulation of actin cytoskeleton 💬
 [2] MAP2K1, MAP2K2 💬 Binimetinib 💬 Binimetinib [1] 34 💬
46 Regulation of actin cytoskeleton 💬
 [2] MAP2K1, MAP2K2 💬 Cobimetinib 💬 Cobimetinib [1] 280 💬
47 Regulation of actin cytoskeleton 💬
 [2] MAP2K1, MAP2K2 💬 Mirdametinib 💬 Mirdametinib [1] 34 💬
48 Regulation of actin cytoskeleton 💬
 [2] MAP2K1, MAP2K2 💬 Selumetinib 💬 Selumetinib [1] 34 💬
49 Regulation of actin cytoskeleton 💬
 [2] MAP2K1, MAP2K2 💬 Trametinib 💬 Trametinib [4]  2 , 34, 279, 280 💬
50 Regulation of actin cytoskeleton 💬
 [1] PDGFRA 💬 Imatinib 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
51 Regulation of actin cytoskeleton 💬
 [2] PDGFRA, PDGFRB 💬 Nilotinib 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
52 Regulation of actin cytoskeleton 💬
 [2] PDGFRA, PDGFRB 💬 Sunitinib 💬 Sunitinib [2] 28, 34 💬
53 Regulation of actin cytoskeleton 💬
 [2] PDGFRB, SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
54 Regulation of actin cytoskeleton 💬
 [2] PDGFRB, SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
55 Regulation of actin cytoskeleton 💬
 [1] PIK3CA 💬 Alpelisib 💬 Alpelisib [1] 138 💬
56 Regulation of actin cytoskeleton 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 Leniolisib 💬 Leniolisib [2] 53, 65 💬
57 Regulation of actin cytoskeleton 💬
 [1] PIK3CD 💬 Parsaclisib 💬 Parsaclisib [3] 35, 53, 61 💬
58 Regulation of actin cytoskeleton 💬
 [2] ROCK1, ROCK2 💬 Fasudil 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
59 Regulation of actin cytoskeleton 💬
 [1] ROCK2 💬 Belumosudil 💬 Belumosudil [2] 51, 85 💬
60 Regulation of actin cytoskeleton 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
61 Regulation of actin cytoskeleton 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬