Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Progesterone-mediated oocyte maturation 💬
 [1] BRAF 💬 Dabrafenib 💬 Dabrafenib [1] 34 💬
2 Progesterone-mediated oocyte maturation 💬
 [2] BRAF, RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
3 Progesterone-mediated oocyte maturation 💬
 [1] IGF1R 💬 Linsitinib 💬 Linsitinib [1] 232 💬
4 Progesterone-mediated oocyte maturation 💬
 [1] IGF1R 💬 Mecasermin 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
5 Progesterone-mediated oocyte maturation 💬
 [1] IGF1R 💬 Teprotumumab 💬 Teprotumumab [1] 51 💬
6 Progesterone-mediated oocyte maturation 💬
 [1] MAP2K1 💬 Binimetinib 💬 Binimetinib [1] 34 💬
7 Progesterone-mediated oocyte maturation 💬
 [1] MAP2K1 💬 Cobimetinib 💬 Cobimetinib [1] 280 💬
8 Progesterone-mediated oocyte maturation 💬
 [1] MAP2K1 💬 Mirdametinib 💬 Mirdametinib [1] 34 💬
9 Progesterone-mediated oocyte maturation 💬
 [1] MAP2K1 💬 Selumetinib 💬 Selumetinib [1] 34 💬
10 Progesterone-mediated oocyte maturation 💬
 [1] MAP2K1 💬 Trametinib 💬 Trametinib [4]  2 , 34, 279, 280 💬
11 Progesterone-mediated oocyte maturation 💬
 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 Losmapimod 💬 Losmapimod [2] 113, 222 💬
12 Progesterone-mediated oocyte maturation 💬
 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 Neflamapimod 💬 Neflamapimod [1]  8  💬
13 Progesterone-mediated oocyte maturation 💬
 [1] PDE3B 💬 Aminophylline 💬 Aminophylline [1] 63 💬
14 Progesterone-mediated oocyte maturation 💬
 [1] PDE3B 💬 Bucladesine 💬 Bucladesine [1] 246 💬
15 Progesterone-mediated oocyte maturation 💬
 [1] PDE3B 💬 Caffeine 💬 Caffeine [8]  2 ,  6 , 21, 46, 78, 96, 97, 265 💬
16 Progesterone-mediated oocyte maturation 💬
 [1] PDE3B 💬 Caffeine hydrate 💬 Caffeine [8]  2 ,  6 , 21, 46, 78, 96, 97, 265 💬
17 Progesterone-mediated oocyte maturation 💬
 [1] PDE3B 💬 Cilostazol 💬 Cilostazol [3] 46, 51, 70 💬
18 Progesterone-mediated oocyte maturation 💬
 [1] PDE3B 💬 Flavoxate 💬 Flavoxate [1] 226 💬
19 Progesterone-mediated oocyte maturation 💬
 [1] PDE3B 💬 Ibudilast 💬 Ibudilast [2]  2 , 13 💬
20 Progesterone-mediated oocyte maturation 💬
 [1] PDE3B 💬 Levosimendan 💬 Levosimendan [1]  2  💬
21 Progesterone-mediated oocyte maturation 💬
 [1] PDE3B 💬 Milrinone 💬 Milrinone [1] 294 💬
22 Progesterone-mediated oocyte maturation 💬
 [1] PDE3B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
23 Progesterone-mediated oocyte maturation 💬
 [1] PDE3B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
24 Progesterone-mediated oocyte maturation 💬
 [1] PGR 💬 Danazol 💬 Danazol [5] 60, 63, 64, 65, 285 💬
25 Progesterone-mediated oocyte maturation 💬
 [1] PGR 💬 Desogestrel 💬 Desogestrel [1] 230 💬
26 Progesterone-mediated oocyte maturation 💬
 [1] PGR 💬 Dydrogesterone 💬 Dydrogesterone [1] 13 💬
27 Progesterone-mediated oocyte maturation 💬
 [1] PGR 💬 Levonorgestrel 💬 Levonorgestrel [1] 13 💬
28 Progesterone-mediated oocyte maturation 💬
 [1] PGR 💬 Medroxyprogesterone acetate 💬 Medroxyprogesterone acetate [8] 13, 35, 46, 49, 50, 51, 60, 107 💬
29 Progesterone-mediated oocyte maturation 💬
 [1] PGR 💬 Megestrol acetate 💬 Megestrol acetate [1] 76 💬
30 Progesterone-mediated oocyte maturation 💬
 [1] PGR 💬 Mifepristone 💬 Mifepristone [1] 75 💬
31 Progesterone-mediated oocyte maturation 💬
 [1] PGR 💬 Nomegestrol 💬 Nomegestrol [1] 13 💬
32 Progesterone-mediated oocyte maturation 💬
 [1] PGR 💬 Nomegestrol acetate 💬 Nomegestrol acetate [1] 13 💬
33 Progesterone-mediated oocyte maturation 💬
 [1] PGR 💬 Norethindrone 💬 Norethisterone [4] 13, 46, 49, 299 💬
34 Progesterone-mediated oocyte maturation 💬
 [1] PGR 💬 Norgestimate 💬 Norgestimate [1] 299 💬
35 Progesterone-mediated oocyte maturation 💬
 [1] PGR 💬 Progesterone 💬 Progesterone [2] 76, 299 💬
36 Progesterone-mediated oocyte maturation 💬
 [1] PGR 💬 Ulipristal 💬 Ulipristal [1] 10 💬
37 Progesterone-mediated oocyte maturation 💬
 [1] PIK3CA 💬 Alpelisib 💬 Alpelisib [1] 138 💬
38 Progesterone-mediated oocyte maturation 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 Leniolisib 💬 Leniolisib [2] 53, 65 💬
39 Progesterone-mediated oocyte maturation 💬
 [1] PIK3CD 💬 Parsaclisib 💬 Parsaclisib [3] 35, 53, 61 💬
40 Progesterone-mediated oocyte maturation 💬
 [1] PLK1 💬 Rigosertib 💬 Rigosertib [1] 36 💬