Gene

Name	Full Name
GRIA1	glutamate ionotropic receptor AMPA type subunit 1
GRIA2	glutamate ionotropic receptor AMPA type subunit 2
GRIA3	glutamate ionotropic receptor AMPA type subunit 3
GRIA4	glutamate ionotropic receptor AMPA type subunit 4

Perampanel 💬

Perampanel

[3] 2 , 6 , 144 💬

Huntington disease 💬

[4] GRIA1, GRIA2, GRIA3, GRIA4 💬

Name	Full Name
GRIA1	glutamate ionotropic receptor AMPA type subunit 1
GRIA2	glutamate ionotropic receptor AMPA type subunit 2
GRIA3	glutamate ionotropic receptor AMPA type subunit 3
GRIA4	glutamate ionotropic receptor AMPA type subunit 4

Talampanel 💬

Talampanel

[2] 2 , 6 💬

Huntington disease 💬

[4] GRIA1, GRIA2, GRIA3, GRIA4 💬

Name	Full Name
GRIA1	glutamate ionotropic receptor AMPA type subunit 1
GRIA2	glutamate ionotropic receptor AMPA type subunit 2
GRIA3	glutamate ionotropic receptor AMPA type subunit 3
GRIA4	glutamate ionotropic receptor AMPA type subunit 4

Topiramate 💬

Topiramate

[6] 6 , 97, 140, 144, 156, 193 💬

Huntington disease 💬

[6] GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2B 💬

Name	Full Name
GRIA1	glutamate ionotropic receptor AMPA type subunit 1
GRIA2	glutamate ionotropic receptor AMPA type subunit 2
GRIA3	glutamate ionotropic receptor AMPA type subunit 3
GRIA4	glutamate ionotropic receptor AMPA type subunit 4
GRIN1	glutamate ionotropic receptor NMDA type subunit 1
GRIN2B	glutamate ionotropic receptor NMDA type subunit 2B

Riluzole 💬

Riluzole

[9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
3	Spinal muscular atrophy;Myelopathic muscular atrophy;
5	Progressive supranuclear palsy;PSP;
8	Huntington disease;Huntington chorea;
13	Multiple sclerosis/Neuromyelitis optica;
17	Multiple system atrophy;MSA-C;MSA-P;
18	Spinocerebellar degeneration;SCD;
203	22q11.2 deletion syndrome;
206	Fragile X syndrome;

Huntington disease 💬

[2] GRIN1, GRIN2B 💬

Acamprosate 💬

Acamprosate

[2] 6 , 206 💬

Huntington disease 💬

[2] GRIN1, GRIN2B 💬

Amantadine 💬

Amantadine

[4] 6 , 8 , 13, 127 💬

Huntington disease 💬

[2] GRIN1, GRIN2B 💬

Dextromethorphan 💬

Dextromethorphan

[11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
6	Parkinson disease;Disease Parkinson's;
8	Huntington disease;Huntington chorea;
13	Multiple sclerosis/Neuromyelitis optica;
21	Mitochondrial disease;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
78	Hypopituitarism;Anterior pituitary hypothyroidism;
85	Idiopathic interstitial pneumonia;IIPs;
96	Crohn disease;Terminal ileitis;
97	Ulcerative colitis;
156	Rett syndrome;

Huntington disease 💬

[2] GRIN1, GRIN2B 💬

Esketamine 💬

Esketamine

[3] 2 , 4 , 70 💬

Huntington disease 💬

[2] GRIN1, GRIN2B 💬

Ketamine 💬

Ketamine

[8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
4	Primary lateral sclerosis;PLS;
6	Parkinson disease;Disease Parkinson's;
13	Multiple sclerosis/Neuromyelitis optica;
70	Spinal stenosis;Extensive spinal canal stenosis;
113	Muscular dystrophy;
156	Rett syndrome;
215	Tetralogy of Fallot;Fallot tetralogy;

Huntington disease 💬

[2] GRIN1, GRIN2B 💬

Latrepirdine 💬

Latrepirdine

[1] 8 💬

Huntington disease 💬

[2] GRIN1, GRIN2B 💬

Memantine 💬

Memantine

[8] 2 , 6 , 8 , 13, 49, 127, 205, 206 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
6	Parkinson disease;Disease Parkinson's;
8	Huntington disease;Huntington chorea;
13	Multiple sclerosis/Neuromyelitis optica;
49	Systemic lupus erythematosus;SLE;
127	Frontotemporal lobar degeneration;
205	Fragile X syndrome related disease;Fragile X-associated tremor/ataxia syndrome;FXTAS;
206	Fragile X syndrome;

Huntington disease 💬

[2] HDAC1, HDAC2 💬

Vorinostat 💬

Vorinostat

[2] 75, 96 💬

Huntington disease 💬

[1] MAP3K5 💬

Selonsertib 💬

Selonsertib

[1] 86 💬

Huntington disease 💬

[1] MTOR 💬

Everolimus 💬

Everolimus

[9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬

Disease ID	Name
34	Neurofibromatosis;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;
89	Lymphangioleiomyomatosis;LAM;
96	Crohn disease;Terminal ileitis;
137	Focal cortical dysplasia;FCD;
157	Sturge-Weber syndrome;Síndrome de Sturge-Weber;
158	Tuberous sclerosis;Tuberous sclerosis complex;
228	Bronchiolitis obliterans;Obliterating bronchiolitis;
277	Lymphangiomatosis;Generalized lymphatic anomaly;Gorham disease;Gorham-Stout disease;Diffuse lymphangiomatosis;Mass osteolysis;

Huntington disease 💬

[1] MTOR 💬

Sirolimus 💬

Sirolimus

[40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
13	Multiple sclerosis/Neuromyelitis optica;
15	Inclusion body myositis;
17	Multiple system atrophy;MSA-C;MSA-P;
19	Lysosomal storage disease;Lysosomal disease;
34	Neurofibromatosis;
35	Pemphigus;
36	Epidermolysis bullosa;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
49	Systemic lupus erythematosus;SLE;
51	Scleroderma;Systemic sclerosis;SSc;
53	Sjogren syndrome;Sjögren syndrome;Syndrome Sjogren's;SS;Autoimmune exocrinopathy;
60	Aplastic anemia;
61	Autoimmune hemolytic anemia;AIHA;
62	Paroxysmal nocturnal hemoglobinuria;PNH;
63	Idiopathic thrombocytopenic purpura;Primary immune thrombocytopenia;
65	Primary immunodeficiency;
66	IgA nephropathy;IgA nephritis;Berger disease;IgA-IgG nephropathy;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;
84	Sarcoidosis;
85	Idiopathic interstitial pneumonia;IIPs;
86	Pulmonary arterial hypertension;PAH;
89	Lymphangioleiomyomatosis;LAM;
96	Crohn disease;Terminal ileitis;
98	Eosinophilic gastrointestinal disease;Eosinophilic gastroenteritis;Eosinophilic esophagitis;Eosinophilic colitis;Eosinophilic gastro-intestinal disorder;EGID;
137	Focal cortical dysplasia;FCD;
157	Sturge-Weber syndrome;Síndrome de Sturge-Weber;
158	Tuberous sclerosis;Tuberous sclerosis complex;
192	Cockayne syndrome;CS;
193	Prader-Willi syndrome;
222	Primary nephrotic syndrome;
256	Muscle glycogenosis;Muscular glycogenosis;Muscle glycogen storage disease;Muscular glycogen storage disease;
277	Lymphangiomatosis;Generalized lymphatic anomaly;Gorham disease;Gorham-Stout disease;Diffuse lymphangiomatosis;Mass osteolysis;
278	Huge lymphatic malformation with cervicofacial lesion;Huge lymphatic malformation;Lymphatic malformation;
279	Huge venous malformation with cervical, oral and pharyngeal diffuse lesion;Huge venous malformation;Venous malformation;
280	Huge arteriovenous malformation with cervicofacial or limb lesion;Huge arteriovenous malformation;Arteriovenous malformation;
281	Klippel-Trenaunay-Weber syndrome;Klippel-Trenauney-Weber syndrome;
283	Acquired pure red cell aplasia;Pure red cell aplasia;
300	IgG4-related disease;
331	Idiopathic multicentric castleman disease;iMCD;Castleman disease;

Huntington disease 💬

[1] MTOR 💬

Temsirolimus 💬

Temsirolimus

[1] 13 💬

Huntington disease 💬

[1] PPARG 💬

Bocidelpar 💬

Bocidelpar

[1] 113 💬

Huntington disease 💬

[1] PPARG 💬

Leriglitazone 💬

Leriglitazone

[1] 20 💬

Huntington disease 💬

[1] PPARG 💬

Pioglitazone 💬

Pioglitazone

[17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
6	Parkinson disease;Disease Parkinson's;
13	Multiple sclerosis/Neuromyelitis optica;
15	Inclusion body myositis;
20	Adrenoleukodystrophy;ALD;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
49	Systemic lupus erythematosus;SLE;
65	Primary immunodeficiency;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;
78	Hypopituitarism;Anterior pituitary hypothyroidism;
81	Congenital adrenal hyperplasia;CAH;Congenital adrenal enzyme deficiency;Congenial adrenal cortex enzyme deficiency;
86	Pulmonary arterial hypertension;PAH;
96	Crohn disease;Terminal ileitis;
229	Autoimmune pulmonary alveolar proteinosis;Congenital pulmonary alveolar proteinosis;Hereditary pulmonary alveolar proteinosis;Pulmonary alveolar proteinosis;PAP;
265	Lipodystrophy;
298	Hereditary pancreatitis;Chronic pancreatitis;
299	Cystic fibrosis;

Huntington disease 💬

[1] PPARG 💬

Rosiglitazone 💬

Rosiglitazone

[5] 46, 75, 97, 222, 265 💬

Huntington disease 💬

[1] PPARG 💬

Seladelpar 💬

Seladelpar

[2] 93, 94 💬

Huntington disease 💬

[1] PSMB5 💬

Bortezomib 💬

Bortezomib

[17] 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 222, 228, 256, 283, 288, 331 💬

Disease ID	Name
11	Myasthenia gravis;MG;
13	Multiple sclerosis/Neuromyelitis optica;
26	HTLV-1-associated myelopathy;Tropical spastic paraparesis;HTLV-1;HTLV-I-associated myelopathy;HAM;
28	Systemic amyloidosis;AL amyloidosis;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
49	Systemic lupus erythematosus;SLE;
51	Scleroderma;Systemic sclerosis;SSc;
61	Autoimmune hemolytic anemia;AIHA;
63	Idiopathic thrombocytopenic purpura;Primary immune thrombocytopenia;
64	Thrombotic thrombocytopenic purpura;TTP;
66	IgA nephropathy;IgA nephritis;Berger disease;IgA-IgG nephropathy;
222	Primary nephrotic syndrome;
228	Bronchiolitis obliterans;Obliterating bronchiolitis;
256	Muscle glycogenosis;Muscular glycogenosis;Muscle glycogen storage disease;Muscular glycogen storage disease;
283	Acquired pure red cell aplasia;Pure red cell aplasia;
288	Autoimmune acquired coagulation factor deficiency;Coagulation factor deficiency;
331	Idiopathic multicentric castleman disease;iMCD;Castleman disease;

Huntington disease 💬

[1] PSMB5 💬

Carfilzomib 💬

Carfilzomib

[1] 28 💬

Huntington disease 💬

[1] PSMB5 💬

Ixazomib 💬

Ixazomib

[5] 13, 16, 28, 51, 61 💬

Disease ID	Name
13	Multiple sclerosis/Neuromyelitis optica;
16	Crow-Fukase syndrome;POEMS syndrome;
28	Systemic amyloidosis;AL amyloidosis;
51	Scleroderma;Systemic sclerosis;SSc;
61	Autoimmune hemolytic anemia;AIHA;

Huntington disease 💬

[1] SOD1 💬

Tofersen 💬

Tofersen

[1] 2 💬

Huntington disease 💬

[9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬

Name	Full Name
TUBB	tubulin beta class I
TUBB1	tubulin beta 1 class VI
TUBB2A	tubulin beta 2A class IIa
TUBB2B	tubulin beta 2B class IIb
TUBB3	tubulin beta 3 class III
TUBB4A	tubulin beta 4A class IVa
TUBB4B	tubulin beta 4B class IVb
TUBB6	tubulin beta 6 class V
TUBB8	tubulin beta 8 class VIII

Belantamab mafodotin 💬

Belantamab mafodotin

[1] 28 💬

Huntington disease 💬

[9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬

Name	Full Name
TUBB	tubulin beta class I
TUBB1	tubulin beta 1 class VI
TUBB2A	tubulin beta 2A class IIa
TUBB2B	tubulin beta 2B class IIb
TUBB3	tubulin beta 3 class III
TUBB4A	tubulin beta 4A class IVa
TUBB4B	tubulin beta 4B class IVb
TUBB6	tubulin beta 6 class V
TUBB8	tubulin beta 8 class VIII

Brentuximab vedotin 💬

Brentuximab vedotin

[2] 49, 51 💬

Huntington disease 💬

[9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬

Name	Full Name
TUBB	tubulin beta class I
TUBB1	tubulin beta 1 class VI
TUBB2A	tubulin beta 2A class IIa
TUBB2B	tubulin beta 2B class IIb
TUBB3	tubulin beta 3 class III
TUBB4A	tubulin beta 4A class IVa
TUBB4B	tubulin beta 4B class IVb
TUBB6	tubulin beta 6 class V
TUBB8	tubulin beta 8 class VIII

Colchicine 💬

Colchicine

[7] 2 , 42, 46, 56, 93, 210, 266 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
42	Polyarteritis nodosa;PAN;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
56	Behcet disease;Behçet disease;BD;
93	Primary biliary cholangitis;Primary biliary cirrhosis;PBC;
210	Single Ventricle;SV;Single ventricle heart defect;Univentricular heart;UVH;Single ventricular circulation syndrome;
266	Familial mediterranean fever;

Huntington disease 💬

[9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬

Name	Full Name
TUBB	tubulin beta class I
TUBB1	tubulin beta 1 class VI
TUBB2A	tubulin beta 2A class IIa
TUBB2B	tubulin beta 2B class IIb
TUBB3	tubulin beta 3 class III
TUBB4A	tubulin beta 4A class IVa
TUBB4B	tubulin beta 4B class IVb
TUBB6	tubulin beta 6 class V
TUBB8	tubulin beta 8 class VIII

Paclitaxel 💬

Paclitaxel

[2] 46, 85 💬

Huntington disease 💬

[9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬

Name	Full Name
TUBB	tubulin beta class I
TUBB1	tubulin beta 1 class VI
TUBB2A	tubulin beta 2A class IIa
TUBB2B	tubulin beta 2B class IIb
TUBB3	tubulin beta 3 class III
TUBB4A	tubulin beta 4A class IVa
TUBB4B	tubulin beta 4B class IVb
TUBB6	tubulin beta 6 class V
TUBB8	tubulin beta 8 class VIII

Vinblastine 💬

Vinblastine

[2] 34, 65 💬

Huntington disease 💬

[9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬

Name	Full Name
TUBB	tubulin beta class I
TUBB1	tubulin beta 1 class VI
TUBB2A	tubulin beta 2A class IIa
TUBB2B	tubulin beta 2B class IIb
TUBB3	tubulin beta 3 class III
TUBB4A	tubulin beta 4A class IVa
TUBB4B	tubulin beta 4B class IVb
TUBB6	tubulin beta 6 class V
TUBB8	tubulin beta 8 class VIII

Vincristine 💬

Vincristine

[4] 26, 34, 65, 331 💬

Disease ID	Name
26	HTLV-1-associated myelopathy;Tropical spastic paraparesis;HTLV-1;HTLV-I-associated myelopathy;HAM;
34	Neurofibromatosis;
65	Primary immunodeficiency;
331	Idiopathic multicentric castleman disease;iMCD;Castleman disease;