Gene

Search results

No.

KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related

Alcoholism 💬

[1] ADORA2A 💬

Caffeine 💬

Caffeine

[8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
6	Parkinson disease;Disease Parkinson's;
21	Mitochondrial disease;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
78	Hypopituitarism;Anterior pituitary hypothyroidism;
96	Crohn disease;Terminal ileitis;
97	Ulcerative colitis;
265	Lipodystrophy;

Alcoholism 💬

[1] ADORA2A 💬

Caffeine hydrate 💬

Caffeine

[8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
6	Parkinson disease;Disease Parkinson's;
21	Mitochondrial disease;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
78	Hypopituitarism;Anterior pituitary hypothyroidism;
96	Crohn disease;Terminal ileitis;
97	Ulcerative colitis;
265	Lipodystrophy;

Alcoholism 💬

[1] ADORA2A 💬

Istradefylline 💬

Istradefylline

[1] 6 💬

Alcoholism 💬

[1] ADORA2A 💬

Preladenant 💬

Preladenant

[1] 6 💬

Alcoholism 💬

[1] ADORA2A 💬

Regadenoson 💬

Regadenoson

[1] 58 💬

Alcoholism 💬

[1] ADORA2A 💬

Regadenoson 💬

Regadenoson

[1] 58 💬

Alcoholism 💬

[1] ADORA2A 💬

Tozadenant 💬

Tozadenant

[1] 6 💬

Alcoholism 💬

[2] ADORA2A, ADORA2B 💬

Adenosine 💬

Adenosine

[3] 13, 58, 65 💬

Alcoholism 💬

[2] ADORA2A, ADORA2B 💬

Adenosine phosphate 💬

Adenosine phosphate

[1] 46 💬

Alcoholism 💬

[1] ADORA2B 💬

Aminophylline 💬

Aminophylline

[1] 63 💬

Alcoholism 💬

[1] ADORA2B 💬

Theophylline 💬

Theophylline

[2] 236, 299 💬

Alcoholism 💬

[1] ADORA2B 💬

Theophylline 💬

Theophylline

[2] 236, 299 💬

Alcoholism 💬

[1] BRAF 💬

Dabrafenib 💬

Dabrafenib

[1] 34 💬

Alcoholism 💬

[2] BRAF, RAF1 💬

Sorafenib 💬

Sorafenib

[2] 34, 86 💬

Alcoholism 💬

[1] DDC 💬

Benserazide 💬

Benserazide

[1] 6 💬

Alcoholism 💬

[1] DDC 💬

Carbidopa 💬

Carbidopa

[7] 6 , 13, 17, 90, 140, 164, 201 💬

Disease ID	Name
6	Parkinson disease;Disease Parkinson's;
13	Multiple sclerosis/Neuromyelitis optica;
17	Multiple system atrophy;MSA-C;MSA-P;
90	Retinitis pigmentosa;
140	Dorabe syndrome;Dravet syndrome;
164	Oculocutaneous albinism;
201	Angelman syndrome;

Alcoholism 💬

[1] DRD1 💬

Tavapadon 💬

Tavapadon

[1] 6 💬

Alcoholism 💬

[2] DRD1, DRD2 💬

Apomorphine 💬

Apomorphine

[3] 5 , 6 , 7 💬

Alcoholism 💬

[2] DRD1, DRD2 💬

Dexpramipexole 💬

Dexpramipexole

[1] 2 💬

Alcoholism 💬

[2] DRD1, DRD2 💬

Dopamine 💬

Dopamine

[4] 6 , 7 , 74, 299 💬

Disease ID	Name
6	Parkinson disease;Disease Parkinson's;
7	Corticobasal degeneration;Corticobasal syndrome;CBD;
74	Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma;
299	Cystic fibrosis;

Alcoholism 💬

[2] DRD1, DRD2 💬

Flupentixol 💬

Flupentixol

[1] 97 💬

Alcoholism 💬

[2] DRD1, DRD2 💬

Foslevodopa 💬

Foslevodopa

[1] 6 💬

Alcoholism 💬

[2] DRD1, DRD2 💬

Levodopa 💬

Levodopa

[6] 6 , 17, 90, 140, 164, 201 💬

Disease ID	Name
6	Parkinson disease;Disease Parkinson's;
17	Multiple system atrophy;MSA-C;MSA-P;
90	Retinitis pigmentosa;
140	Dorabe syndrome;Dravet syndrome;
164	Oculocutaneous albinism;
201	Angelman syndrome;

Alcoholism 💬

[2] DRD1, DRD2 💬

Pergolide 💬

Pergolide

[1] 6 💬

Alcoholism 💬

[1] DRD2 💬

Aripiprazole 💬

Aripiprazole

[2] 6 , 206 💬

Alcoholism 💬

[1] DRD2 💬

Bromocriptine 💬

Bromocriptine

[2] 6 , 74 💬

Alcoholism 💬

[1] DRD2 💬

Buspirone 💬

Buspirone

[2] 6 , 51 💬

Alcoholism 💬

[1] DRD2 💬

Cabergoline 💬

Cabergoline

[3] 6 , 74, 75 💬

Disease ID	Name
6	Parkinson disease;Disease Parkinson's;
74	Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma;
75	Cushing disease;Cushing;

Alcoholism 💬

[1] DRD2 💬

Cariprazine 💬

Cariprazine

[1] 21 💬

Alcoholism 💬

[1] DRD2 💬

Chlorpromazine 💬

Chlorpromazine

[1] 254 💬

Alcoholism 💬

[1] DRD2 💬

Domperidone 💬

Domperidone

[5] 6 , 13, 17, 51, 230 💬

Disease ID	Name
6	Parkinson disease;Disease Parkinson's;
13	Multiple sclerosis/Neuromyelitis optica;
17	Multiple system atrophy;MSA-C;MSA-P;
51	Scleroderma;Systemic sclerosis;SSc;
230	Alveolar hypoventilation syndrome;AHS;Hypoventilation syndrome;

Alcoholism 💬

[1] DRD2 💬

Domperidone maleate 💬

Domperidone

[5] 6 , 13, 17, 51, 230 💬

Disease ID	Name
6	Parkinson disease;Disease Parkinson's;
13	Multiple sclerosis/Neuromyelitis optica;
17	Multiple system atrophy;MSA-C;MSA-P;
51	Scleroderma;Systemic sclerosis;SSc;
230	Alveolar hypoventilation syndrome;AHS;Hypoventilation syndrome;

Alcoholism 💬

[1] DRD2 💬

Haloperidol 💬

Haloperidol

[1] 8 💬

Alcoholism 💬

[1] DRD2 💬

Iloperidone 💬

Iloperidone

[1] 6 💬

Alcoholism 💬

[1] DRD2 💬

Lisuride 💬

Lisuride

[2] 6 , 86 💬

Alcoholism 💬

[1] DRD2 💬

Melperone 💬

Melperone

[1] 6 💬

Alcoholism 💬

[1] DRD2 💬

Metoclopramide 💬

Metoclopramide

[2] 46, 51 💬

Alcoholism 💬

[1] DRD2 💬

Olanzapine 💬

Olanzapine

[2] 2 , 8 💬

Alcoholism 💬

[1] DRD2 💬

Pardoprunox 💬

Pardoprunox

[1] 6 💬

Alcoholism 💬

[1] DRD2 💬

Pimozide 💬

Pimozide

[1] 2 💬

Alcoholism 💬

[1] DRD2 💬

Piribedil 💬

Piribedil

[1] 6 💬

Alcoholism 💬

[1] DRD2 💬

Pramipexole 💬

Pramipexole

[3] 2 , 6 , 20 💬

Alcoholism 💬

[1] DRD2 💬

Pridopidine 💬

Pridopidine

[3] 2 , 6 , 8 💬

Alcoholism 💬

[1] DRD2 💬

Quetiapine 💬

Quetiapine

[2] 6 , 13 💬

Alcoholism 💬

[1] DRD2 💬

Risperidone 💬

Risperidone

[5] 8 , 156, 179, 187, 206 💬

Alcoholism 💬

[1] DRD2 💬

Ropinirole 💬

Ropinirole

[4] 2 , 6 , 74, 309 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
6	Parkinson disease;Disease Parkinson's;
74	Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma;
309	Progressive myoclonus epilepsy;

Alcoholism 💬

[1] DRD2 💬

Rotigotine 💬

Rotigotine

[1] 6 💬

Alcoholism 💬

[1] DRD2 💬

Sulpiride 💬

Sulpiride

[2] 6 , 70 💬

Alcoholism 💬

[1] DRD2 💬

Terguride 💬

Terguride

[2] 51, 86 💬

Alcoholism 💬

[1] DRD2 💬

Tiapride 💬

Tiapride

[1] 8 💬

Alcoholism 💬

[1] DRD2 💬

Trifluoperazine maleate 💬

Trifluoperazine

[2] 283, 284 💬

Alcoholism 💬

[1] DRD2 💬

Trifluoperazine 💬

Trifluoperazine

[2] 283, 284 💬

Alcoholism 💬

[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬

Name	Full Name
GRIN1	glutamate ionotropic receptor NMDA type subunit 1
GRIN2A	glutamate ionotropic receptor NMDA type subunit 2A
GRIN2B	glutamate ionotropic receptor NMDA type subunit 2B
GRIN2C	glutamate ionotropic receptor NMDA type subunit 2C
GRIN2D	glutamate ionotropic receptor NMDA type subunit 2D

Acamprosate 💬

Acamprosate

[2] 6 , 206 💬

Alcoholism 💬

[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬

Name	Full Name
GRIN1	glutamate ionotropic receptor NMDA type subunit 1
GRIN2A	glutamate ionotropic receptor NMDA type subunit 2A
GRIN2B	glutamate ionotropic receptor NMDA type subunit 2B
GRIN2C	glutamate ionotropic receptor NMDA type subunit 2C
GRIN2D	glutamate ionotropic receptor NMDA type subunit 2D

Amantadine 💬

Amantadine

[4] 6 , 8 , 13, 127 💬

Alcoholism 💬

[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬

Name	Full Name
GRIN1	glutamate ionotropic receptor NMDA type subunit 1
GRIN2A	glutamate ionotropic receptor NMDA type subunit 2A
GRIN2B	glutamate ionotropic receptor NMDA type subunit 2B
GRIN2C	glutamate ionotropic receptor NMDA type subunit 2C
GRIN2D	glutamate ionotropic receptor NMDA type subunit 2D

Dextromethorphan 💬

Dextromethorphan

[11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
6	Parkinson disease;Disease Parkinson's;
8	Huntington disease;Huntington chorea;
13	Multiple sclerosis/Neuromyelitis optica;
21	Mitochondrial disease;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
78	Hypopituitarism;Anterior pituitary hypothyroidism;
85	Idiopathic interstitial pneumonia;IIPs;
96	Crohn disease;Terminal ileitis;
97	Ulcerative colitis;
156	Rett syndrome;

Alcoholism 💬

[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬

Name	Full Name
GRIN1	glutamate ionotropic receptor NMDA type subunit 1
GRIN2A	glutamate ionotropic receptor NMDA type subunit 2A
GRIN2B	glutamate ionotropic receptor NMDA type subunit 2B
GRIN2C	glutamate ionotropic receptor NMDA type subunit 2C
GRIN2D	glutamate ionotropic receptor NMDA type subunit 2D

Esketamine 💬

Esketamine

[3] 2 , 4 , 70 💬

Alcoholism 💬

[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬

Name	Full Name
GRIN1	glutamate ionotropic receptor NMDA type subunit 1
GRIN2A	glutamate ionotropic receptor NMDA type subunit 2A
GRIN2B	glutamate ionotropic receptor NMDA type subunit 2B
GRIN2C	glutamate ionotropic receptor NMDA type subunit 2C
GRIN2D	glutamate ionotropic receptor NMDA type subunit 2D

Ketamine 💬

Ketamine

[8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
4	Primary lateral sclerosis;PLS;
6	Parkinson disease;Disease Parkinson's;
13	Multiple sclerosis/Neuromyelitis optica;
70	Spinal stenosis;Extensive spinal canal stenosis;
113	Muscular dystrophy;
156	Rett syndrome;
215	Tetralogy of Fallot;Fallot tetralogy;

Alcoholism 💬

[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬

Name	Full Name
GRIN1	glutamate ionotropic receptor NMDA type subunit 1
GRIN2A	glutamate ionotropic receptor NMDA type subunit 2A
GRIN2B	glutamate ionotropic receptor NMDA type subunit 2B
GRIN2C	glutamate ionotropic receptor NMDA type subunit 2C
GRIN2D	glutamate ionotropic receptor NMDA type subunit 2D

Latrepirdine 💬

Latrepirdine

[1] 8 💬

Alcoholism 💬

[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬

Name	Full Name
GRIN1	glutamate ionotropic receptor NMDA type subunit 1
GRIN2A	glutamate ionotropic receptor NMDA type subunit 2A
GRIN2B	glutamate ionotropic receptor NMDA type subunit 2B
GRIN2C	glutamate ionotropic receptor NMDA type subunit 2C
GRIN2D	glutamate ionotropic receptor NMDA type subunit 2D

Memantine 💬

Memantine

[8] 2 , 6 , 8 , 13, 49, 127, 205, 206 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
6	Parkinson disease;Disease Parkinson's;
8	Huntington disease;Huntington chorea;
13	Multiple sclerosis/Neuromyelitis optica;
49	Systemic lupus erythematosus;SLE;
127	Frontotemporal lobar degeneration;
205	Fragile X syndrome related disease;Fragile X-associated tremor/ataxia syndrome;FXTAS;
206	Fragile X syndrome;

Alcoholism 💬

[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬

Name	Full Name
GRIN1	glutamate ionotropic receptor NMDA type subunit 1
GRIN2A	glutamate ionotropic receptor NMDA type subunit 2A
GRIN2B	glutamate ionotropic receptor NMDA type subunit 2B
GRIN2C	glutamate ionotropic receptor NMDA type subunit 2C
GRIN2D	glutamate ionotropic receptor NMDA type subunit 2D

Riluzole 💬

Riluzole

[9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
3	Spinal muscular atrophy;Myelopathic muscular atrophy;
5	Progressive supranuclear palsy;PSP;
8	Huntington disease;Huntington chorea;
13	Multiple sclerosis/Neuromyelitis optica;
17	Multiple system atrophy;MSA-C;MSA-P;
18	Spinocerebellar degeneration;SCD;
203	22q11.2 deletion syndrome;
206	Fragile X syndrome;

Alcoholism 💬

[11] HDAC1, HDAC10, HDAC11, HDAC2, HDAC3, HDAC4, HDAC5, HDAC6, HDAC7, HDAC8, HDAC9 💬

Name	Full Name
HDAC1	histone deacetylase 1
HDAC10	histone deacetylase 10
HDAC11	histone deacetylase 11
HDAC2	histone deacetylase 2
HDAC3	histone deacetylase 3
HDAC4	histone deacetylase 4
HDAC5	histone deacetylase 5
HDAC6	histone deacetylase 6
HDAC7	histone deacetylase 7
HDAC8	histone deacetylase 8
HDAC9	histone deacetylase 9

Vorinostat 💬

Vorinostat

[2] 75, 96 💬

Alcoholism 💬

[1] MAOA 💬

Moclobemide 💬

Moclobemide

[1] 6 💬

Alcoholism 💬

[2] MAOA, MAOB 💬

Iproniazid 💬

Iproniazid

[1] 6 💬

Alcoholism 💬

[2] MAOA, MAOB 💬

Phenelzine 💬

Phenelzine

[1] 6 💬

Alcoholism 💬

[3] MAOA, MAOB, SLC6A3 💬

Phentermine 💬

Phentermine

[1] 97 💬

Alcoholism 💬

[1] MAOB 💬

Rasagiline 💬

Rasagiline

[6] 2 , 5 , 6 , 17, 58, 66 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
5	Progressive supranuclear palsy;PSP;
6	Parkinson disease;Disease Parkinson's;
17	Multiple system atrophy;MSA-C;MSA-P;
58	Hypertrophic cardiomyopathy;HCM;
66	IgA nephropathy;IgA nephritis;Berger disease;IgA-IgG nephropathy;

Alcoholism 💬

[1] MAOB 💬

Rasagiline tartrate 💬

Rasagiline

[6] 2 , 5 , 6 , 17, 58, 66 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
5	Progressive supranuclear palsy;PSP;
6	Parkinson disease;Disease Parkinson's;
17	Multiple system atrophy;MSA-C;MSA-P;
58	Hypertrophic cardiomyopathy;HCM;
66	IgA nephropathy;IgA nephritis;Berger disease;IgA-IgG nephropathy;

Alcoholism 💬

[1] MAOB 💬

Safinamide 💬

Safinamide

[2] 6 , 17 💬

Alcoholism 💬

[1] MAOB 💬

Selegiline 💬

Selegiline

[1] 6 💬

Alcoholism 💬

[1] MAP2K1 💬

Binimetinib 💬

Binimetinib

[1] 34 💬

Alcoholism 💬

[1] MAP2K1 💬

Cobimetinib 💬

Cobimetinib

[1] 280 💬

Alcoholism 💬

[1] MAP2K1 💬

Mirdametinib 💬

Mirdametinib

[1] 34 💬

Alcoholism 💬

[1] MAP2K1 💬

Selumetinib 💬

Selumetinib

[1] 34 💬

Alcoholism 💬

[1] MAP2K1 💬

Trametinib 💬

Trametinib

[4] 2 , 34, 279, 280 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
34	Neurofibromatosis;
279	Huge venous malformation with cervical, oral and pharyngeal diffuse lesion;Huge venous malformation;Venous malformation;
280	Huge arteriovenous malformation with cervicofacial or limb lesion;Huge arteriovenous malformation;Arteriovenous malformation;

Alcoholism 💬

[1] SLC18A2 💬

Deutetrabenazine 💬

Deutetrabenazine

[1] 8 💬

Alcoholism 💬

[1] SLC18A2 💬

Tetrabenazine 💬

Tetrabenazine

[1] 8 💬

Alcoholism 💬

[1] SLC18A2 💬

Valbenazine 💬

Valbenazine

[1] 8 💬

Alcoholism 💬

[1] SLC6A3 💬

Armodafinil 💬

Armodafinil

[3] 6 , 13, 84 💬

Alcoholism 💬

[1] SLC6A3 💬

Bupropion 💬

Bupropion

[5] 8 , 18, 21, 96, 171 💬

Alcoholism 💬

[1] SLC6A3 💬

Lisdexamfetamine 💬

Lisdexamfetamine

[1] 13 💬

Alcoholism 💬

[1] SLC6A3 💬

Methylphenidate 💬

Methylphenidate

[7] 6 , 13, 34, 84, 113, 179, 206 💬

Disease ID	Name
6	Parkinson disease;Disease Parkinson's;
13	Multiple sclerosis/Neuromyelitis optica;
34	Neurofibromatosis;
84	Sarcoidosis;
113	Muscular dystrophy;
179	Williams syndrome;
206	Fragile X syndrome;