Target Gene/Pathway Pathway / Gene
Search results
| No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related  | KEGG GENES | KEGG DRUG | DrugBank | Disease ID | 
|---|---|---|---|---|---|
| 1 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases  | 
BCL2 [1] BCL2 💬
 | 
Venetoclax  Venetoclax  💬
 | Venetoclax | 028 [1] 28 💬
 | 
| 2 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases  | 
C3 [1] C3 💬
 | 
Pegcetacoplan  Pegcetacoplan  💬
 | Pegcetacoplan | 002 [4]  2 , 61, 62, 222 💬
 | 
| 3 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases  | 
CASP9 [1] CASP9 💬
 | 
Rimiducid  Rimiducid  💬
 | Rimiducid | 019 [6] 19, 60, 65, 284, 285, 326 💬
 | 
| 4 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases  | 
CD74 [1] CD74 💬
 | 
Milatuzumab  Milatuzumab  💬
 | Milatuzumab | 049 [1] 49 💬
 | 
| 5 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases  | 
IFNA1 [13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬
 | 
Rontalizumab  Rontalizumab  💬
 | Rontalizumab | 049 [1] 49 💬
 | 
| 6 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases  | 
IFNA1 [13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬
 | 
Sifalimumab  Sifalimumab  💬
 | Sifalimumab | 049 [1] 49 💬
 | 
| 7 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases  | 
IFNG [1] IFNG 💬
 | 
Emapalumab  Emapalumab  💬
 | Emapalumab | 049 [3] 49, 65, 107 💬
 | 
| 8 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases  | 
IFNG [1] IFNG 💬
 | 
Fontolizumab  Fontolizumab  💬
 | Fontolizumab | 046 [1] 46 💬
 | 
| 9 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases  | 
IFNGR1 [2] IFNGR1, IFNGR2 💬
 | 
Interferon gamma-1b  Interferon gamma-1b  💬
 | Interferon gamma-1b | 018 [7] 18, 65, 85, 228, 299, 301, 326 💬
 | 
| 10 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases  | 
IL10 [5] IL10, IL1A, IL1B, IL6, TNF 💬
 | 
Pirfenidone  Pirfenidone  💬
 | Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
 | 
| 11 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases  | 
IL12A [3] IL12A, IL12B, IL23A 💬
 | 
Ustekinumab  Ustekinumab  💬
 | Ustekinumab | 037 [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
 | 
| 12 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases  | 
IL1A [1] IL1A 💬
 | 
Bermekimab  Bermekimab  💬
 | Bermekimab | 051 [1] 51 💬
 | 
| 13 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases  | 
IL1A [2] IL1A, IL1B 💬
 | 
Rilonacept  Rilonacept  💬
 | Rilonacept | 051 [4] 51, 106, 107, 266 💬
 | 
| 14 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases  | 
IL1B [1] IL1B 💬
 | 
Canakinumab  Canakinumab  💬
 | Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
 | 
| 15 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases  | 
IL1B [1] IL1B 💬
 | 
Gevokizumab  Gevokizumab  💬
 | Gevokizumab | 041 [4] 41, 50, 56, 269 💬
 | 
| 16 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases  | 
IL23A [1] IL23A 💬
 | 
Brazikumab  Brazikumab  💬
 | Brazikumab | 096 [2] 96, 97 💬
 | 
| 17 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases  | 
IL23A [1] IL23A 💬
 | 
Guselkumab  Guselkumab  💬
 | Guselkumab | 037 [5] 37, 41, 51, 96, 97 💬
 | 
| 18 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases  | 
IL23A [1] IL23A 💬
 | 
Mirikizumab  Mirikizumab  💬
 | Mirikizumab | 037 [3] 37, 96, 97 💬
 | 
| 19 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases  | 
IL23A [1] IL23A 💬
 | 
Risankizumab  Risankizumab  💬
 | Risankizumab | 037 [4] 37, 96, 97, 271 💬
 | 
| 20 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases  | 
IL23A [1] IL23A 💬
 | 
Tildrakizumab  Tildrakizumab  💬
 | Tildrakizumab | 162 [2] 162, 271 💬
 | 
| 21 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases  | 
IL6 [1] IL6 💬
 | 
Olokizumab  Olokizumab  💬
 | Olokizumab | 046 [2] 46, 96 💬
 | 
| 22 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases  | 
IL6 [1] IL6 💬
 | 
Siltuximab  Siltuximab  💬
 | Siltuximab | 028 [2] 28, 331 💬
 | 
| 23 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases  | 
IL6 [1] IL6 💬
 | 
Sirukumab  Sirukumab  💬
 | Sirukumab | 041 [2] 41, 46 💬
 | 
| 24 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases  | 
IL6 [2] IL6, TNF 💬
 | 
Pomalidomide  Pomalidomide  💬
 | Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
 | 
| 25 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases  | 
JAK1 [1] JAK1 💬
 | 
Abrocitinib  Abrocitinib  💬
 | Abrocitinib | 084 [1] 84 💬
 | 
| 26 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases  | 
JAK1 [1] JAK1 💬
 | 
Filgotinib  Filgotinib  💬
 | Filgotinib | 046 [6] 46, 53, 96, 97, 222, 271 💬
 | 
| 27 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases  | 
JAK1 [1] JAK1 💬
 | 
Itacitinib  Itacitinib  💬
 | Itacitinib | 046 [4] 46, 51, 97, 228 💬
 | 
| 28 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases  | 
JAK1 [1] JAK1 💬
 | 
Upadacitinib  Upadacitinib  💬
 | Upadacitinib | 040 [8] 40, 41, 46, 49, 96, 97, 107, 271 💬
 | 
| 29 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases  | 
JAK1 [2] JAK1, JAK2 💬
 | 
Baricitinib  Baricitinib  💬
 | Baricitinib | 002 [13]  2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
 | 
| 30 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases  | 
JAK1 [2] JAK1, JAK2 💬
 | 
Peficitinib  Peficitinib  💬
 | Peficitinib | 046 [1] 46 💬
 | 
| 31 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases  | 
JAK1 [2] JAK1, JAK2 💬
 | 
Ruxolitinib  Ruxolitinib  💬
 | Ruxolitinib | 060 [3] 60, 65, 228 💬
 | 
| 32 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases  | 
JAK1 [2] JAK1, JAK2 💬
 | 
Tofacitinib  Tofacitinib  💬
 | Tofacitinib | 011 [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬
 | 
| 33 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases  | 
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
 | 
Losmapimod  Losmapimod  💬
 | Losmapimod | 113 [2] 113, 222 💬
 | 
| 34 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases  | 
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
 | 
Neflamapimod  Neflamapimod  💬
 | Neflamapimod | 008 [1]  8  💬
 | 
| 35 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases  | 
NFKB1 [1] NFKB1 💬
 | 
Iguratimod  Iguratimod  💬
 | Iguratimod | 046 [5] 46, 51, 53, 271, 300 💬
 | 
| 36 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases  | 
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
 | 
Cyclosporine  Cyclosporine  💬
 | Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
 | 
| 37 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases  | 
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
 | 
Pimecrolimus  Pimecrolimus  💬
 | Pimecrolimus | 160 [1] 160 💬
 | 
| 38 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases  | 
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
 | 
Tacrolimus  Tacrolimus  💬
 | Tacrolimus | 002 [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
 | 
| 39 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases  | 
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
 | 
Tacrolimus  Tacrolimus  💬
 | Tacrolimus | 002 [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
 | 
| 40 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases  | 
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
 | 
Voclosporin  Voclosporin  💬
 | Voclosporin | 049 [2] 49, 222 💬
 | 
| 41 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases  | 
RAF1 [1] RAF1 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 42 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases  | 
RELA [1] RELA 💬
 | 
Edasalonexent  Edasalonexent  💬
 | Edasalonexent | 113 [1] 113 💬
 | 
| 43 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases  | 
SRC [1] SRC 💬
 | 
Bosutinib  Bosutinib  💬
 | Bosutinib | 002 [2]  2 , 67 💬
 | 
| 44 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases  | 
SRC [1] SRC 💬
 | 
Dasatinib  Dasatinib  💬
 | Dasatinib | 051 [2] 51, 85 💬
 | 
| 45 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases  | 
SRC [1] SRC 💬
 | 
Dasatinib  Dasatinib  💬
 | Dasatinib | 051 [2] 51, 85 💬
 | 
| 46 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases  | 
SRC [1] SRC 💬
 | 
Saracatinib  Saracatinib  💬
 | Saracatinib | 006 [3]  6 , 89, 272 💬
 | 
| 47 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases  | 
SYK [1] SYK 💬
 | 
Fostamatinib  Fostamatinib  💬
 | Fostamatinib | 046 [4] 46, 49, 61, 66 💬
 | 
| 48 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases  | 
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬
 | 
Fresolimumab  Fresolimumab  💬
 | Fresolimumab | 051 [3] 51, 85, 222 💬
 | 
| 49 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases  | 
TLR9 [1] TLR9 💬
 | 
Cobitolimod  Cobitolimod  💬
 | Cobitolimod | 097 [1] 97 💬
 | 
| 50 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases  | 
TNF [1] TNF 💬
 | 
Adalimumab  Adalimumab  💬
 | Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
 | 
| 51 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases  | 
TNF [1] TNF 💬
 | 
Certolizumab pegol  Certolizumab pegol  💬
 | Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
 | 
| 52 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases  | 
TNF [1] TNF 💬
 | 
Etanercept  Etanercept  💬
 | Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
 | 
| 53 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases  | 
TNF [1] TNF 💬
 | 
Golimumab  Golimumab  💬
 | Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
 | 
| 54 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases  | 
TNF [1] TNF 💬
 | 
Infliximab  Infliximab  💬
 | Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
 | 
| 55 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases  | 
TNF [1] TNF 💬
 | 
Lenalidomide  Lenalidomide  💬
 | Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
 | 
| 56 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases  | 
TNF [1] TNF 💬
 | 
Ozoralizumab  Ozoralizumab  💬
 | Ozoralizumab | 046 [1] 46 💬
 | 
| 57 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases  | 
TNF [1] TNF 💬
 | 
Pegsunercept  Pegsunercept  💬
 | Pegsunercept | 046 [1] 46 💬
 | 
| 58 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases  | 
TNF [1] TNF 💬
 | 
Thalidomide  Thalidomide  💬
 | Thalidomide | 002 [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
 | 
| 59 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases  | 
VDR [1] VDR 💬
 | 
Alfacalcidol  Alfacalcidol  💬
 | Alfacalcidol | 041 [8] 41, 46, 49, 50, 96, 107, 235, 238 💬
 | 
| 60 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases  | 
VDR [1] VDR 💬
 | 
Calcifediol  Calcifediol  💬
 | Calcifediol | 113 [2] 113, 299 💬
 | 
| 61 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases  | 
VDR [1] VDR 💬
 | 
Calcipotriene  Calcipotriene  💬
 | Calcipotriol | 036 [2] 36, 51 💬
 | 
| 62 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases  | 
VDR [1] VDR 💬
 | 
Calcitriol  Calcitriol  💬
 | Calcitriol | 018 [9] 18, 37, 46, 49, 66, 96, 158, 235, 326 💬
 | 
| 63 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases  | 
VDR [1] VDR 💬
 | 
Cholecalciferol  Cholecalciferol  💬
 | Cholecalciferol | 006 [24]  6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬
 | 
| 64 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases  | 
VDR [1] VDR 💬
 | 
Dihydrotachysterol  Dihydrotachysterol  💬
 | Dihydrotachysterol | 006 [2]  6 , 85 💬
 | 
| 65 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases  | 
VDR [1] VDR 💬
 | 
Eldecalcitol  Eldecalcitol  💬
 | Eldecalcitol | 046 [1] 46 💬
 | 
| 66 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases  | 
VDR [1] VDR 💬
 | 
Ergocalciferol  Ergocalciferol  💬
 | Ergocalciferol | 046 [6] 46, 49, 84, 96, 97, 299 💬
 | 
| 67 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases  | 
VDR [1] VDR 💬
 | 
Paricalcitol  Paricalcitol  💬
 | Paricalcitol | 019 [5] 19, 66, 218, 238, 298 💬
 |