Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Influenza A 💬
 [1] CASP9 💬 Rimiducid 💬 Rimiducid [6] 19, 60, 65, 284, 285, 326 💬
2 Influenza A 💬
 [5] CCL2, IL1A, IL1B, IL6, TNF 💬 Pirfenidone 💬 Pirfenidone [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
3 Influenza A 💬
 [2] CDK4, CDK6 💬 Abemaciclib 💬 Abemaciclib [1] 34 💬
4 Influenza A 💬
 [1] FDPS 💬 Alendronic acid 💬 Alendronic acid [7] 19, 41, 46, 50, 271, 274, 299 💬
5 Influenza A 💬
 [1] FDPS 💬 Pamidronic acid 💬 Pamidronic acid [3] 270, 271, 274 💬
6 Influenza A 💬
 [1] FDPS 💬 Risedronic acid 💬 Risedronic acid [9] 46, 50, 66, 93, 95, 96, 107, 113, 274 💬
7 Influenza A 💬
 [1] FDPS 💬 Zoledronic acid 💬 Zoledronic acid [13]  5 ,  6 , 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬
8 Influenza A 💬
 [1] FDPS 💬 Zoledronic acid 💬 Zoledronic acid [13]  5 ,  6 , 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬
9 Influenza A 💬
 [13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬 Rontalizumab 💬 Rontalizumab [1] 49 💬
10 Influenza A 💬
 [13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬 Sifalimumab 💬 Sifalimumab [1] 49 💬
11 Influenza A 💬
 [2] IFNAR1, IFNAR2 💬 Anifrolumab 💬 Anifrolumab [3] 46, 49, 53 💬
12 Influenza A 💬
 [2] IFNAR1, IFNAR2 💬 Interferon alfa 💬 Interferon alfa [6] 13, 25, 26, 28, 56, 96 💬
13 Influenza A 💬
 [2] IFNAR1, IFNAR2 💬 Interferon alfa-2a 💬 Interferon alfa-2a [1] 56 💬
14 Influenza A 💬
 [2] IFNAR1, IFNAR2 💬 Interferon alfa-2b 💬 Interferon alfa-2b [2] 25, 34 💬
15 Influenza A 💬
 [2] IFNAR1, IFNAR2 💬 Interferon beta-1a 💬 Interferon beta-1a [4] 13, 26, 96, 97 💬
16 Influenza A 💬
 [2] IFNAR1, IFNAR2 💬 Interferon beta-1b 💬 Interferon beta-1b [1] 13 💬
17 Influenza A 💬
 [2] IFNAR1, IFNAR2 💬 Peginterferon beta-1a 💬 Peginterferon beta-1a [1] 13 💬
18 Influenza A 💬
 [1] IFNG 💬 Emapalumab 💬 Emapalumab [3] 49, 65, 107 💬
19 Influenza A 💬
 [1] IFNG 💬 Fontolizumab 💬 Fontolizumab [1] 46 💬
20 Influenza A 💬
 [2] IFNGR1, IFNGR2 💬 Interferon gamma-1b 💬 Interferon gamma-1b [7] 18, 65, 85, 228, 299, 301, 326 💬
21 Influenza A 💬
 [2] IL12A, IL12B 💬 Ustekinumab 💬 Ustekinumab [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
22 Influenza A 💬
 [1] IL1A 💬 Bermekimab 💬 Bermekimab [1] 51 💬
23 Influenza A 💬
 [2] IL1A, IL1B 💬 Rilonacept 💬 Rilonacept [4] 51, 106, 107, 266 💬
24 Influenza A 💬
 [1] IL1B 💬 Canakinumab 💬 Canakinumab [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
25 Influenza A 💬
 [1] IL1B 💬 Gevokizumab 💬 Gevokizumab [4] 41, 50, 56, 269 💬
26 Influenza A 💬
 [1] IL6 💬 Olokizumab 💬 Olokizumab [2] 46, 96 💬
27 Influenza A 💬
 [1] IL6 💬 Siltuximab 💬 Siltuximab [2] 28, 331 💬
28 Influenza A 💬
 [1] IL6 💬 Sirukumab 💬 Sirukumab [2] 41, 46 💬
29 Influenza A 💬
 [2] IL6, TNF 💬 Pomalidomide 💬 Pomalidomide [5] 28, 51, 85, 227, 331 💬
30 Influenza A 💬
 [1] JAK1 💬 Abrocitinib 💬 Abrocitinib [1] 84 💬
31 Influenza A 💬
 [1] JAK1 💬 Filgotinib 💬 Filgotinib [6] 46, 53, 96, 97, 222, 271 💬
32 Influenza A 💬
 [1] JAK1 💬 Itacitinib 💬 Itacitinib [4] 46, 51, 97, 228 💬
33 Influenza A 💬
 [1] JAK1 💬 Upadacitinib 💬 Upadacitinib [8] 40, 41, 46, 49, 96, 97, 107, 271 💬
34 Influenza A 💬
 [2] JAK1, JAK2 💬 Baricitinib 💬 Baricitinib [13]  2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
35 Influenza A 💬
 [2] JAK1, JAK2 💬 Peficitinib 💬 Peficitinib [1] 46 💬
36 Influenza A 💬
 [2] JAK1, JAK2 💬 Ruxolitinib 💬 Ruxolitinib [3] 60, 65, 228 💬
37 Influenza A 💬
 [3] JAK1, JAK2, TYK2 💬 Tofacitinib 💬 Tofacitinib [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬
38 Influenza A 💬
 [2] MAP2K1, MAP2K2 💬 Binimetinib 💬 Binimetinib [1] 34 💬
39 Influenza A 💬
 [2] MAP2K1, MAP2K2 💬 Cobimetinib 💬 Cobimetinib [1] 280 💬
40 Influenza A 💬
 [2] MAP2K1, MAP2K2 💬 Mirdametinib 💬 Mirdametinib [1] 34 💬
41 Influenza A 💬
 [2] MAP2K1, MAP2K2 💬 Selumetinib 💬 Selumetinib [1] 34 💬
42 Influenza A 💬
 [2] MAP2K1, MAP2K2 💬 Trametinib 💬 Trametinib [4]  2 , 34, 279, 280 💬
43 Influenza A 💬
 [1] NFKB1 💬 Iguratimod 💬 Iguratimod [5] 46, 51, 53, 271, 300 💬
44 Influenza A 💬
 [1] PIK3CA 💬 Alpelisib 💬 Alpelisib [1] 138 💬
45 Influenza A 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 Leniolisib 💬 Leniolisib [2] 53, 65 💬
46 Influenza A 💬
 [1] PIK3CD 💬 Parsaclisib 💬 Parsaclisib [3] 35, 53, 61 💬
47 Influenza A 💬
 [1] PLG 💬 Aminocaproic acid 💬 Aminocaproic acid [1] 70 💬
48 Influenza A 💬
 [1] PLG 💬 Tranexamic acid 💬 Tranexamic acid [7] 46, 70, 215, 227, 274, 288, 299 💬
49 Influenza A 💬
 [1] PML 💬 Tretinoin 💬 Tretinoin [6]  2 , 62, 63, 75, 94, 231 💬
50 Influenza A 💬
 [1] PRKCB 💬 Enzastaurin 💬 Enzastaurin [1] 168 💬
51 Influenza A 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
52 Influenza A 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬
53 Influenza A 💬
 [1] TLR7 💬 Imiquimod 💬 Imiquimod [2] 34, 51 💬
54 Influenza A 💬
 [1] TNF 💬 Adalimumab 💬 Adalimumab [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
55 Influenza A 💬
 [1] TNF 💬 Certolizumab pegol 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
56 Influenza A 💬
 [1] TNF 💬 Etanercept 💬 Etanercept [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
57 Influenza A 💬
 [1] TNF 💬 Golimumab 💬 Golimumab [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
58 Influenza A 💬
 [1] TNF 💬 Infliximab 💬 Infliximab [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
59 Influenza A 💬
 [1] TNF 💬 Lenalidomide 💬 Lenalidomide [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
60 Influenza A 💬
 [1] TNF 💬 Ozoralizumab 💬 Ozoralizumab [1] 46 💬
61 Influenza A 💬
 [1] TNF 💬 Pegsunercept 💬 Pegsunercept [1] 46 💬
62 Influenza A 💬
 [1] TNF 💬 Thalidomide 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
63 Influenza A 💬
 [1] TYK2 💬 Deucravacitinib 💬 Deucravacitinib [3] 49, 96, 97 💬
64 Influenza A 💬
 [1] XPO1 💬 Selinexor 💬 Selinexor [1] 28 💬