Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] C3 💬 Pegcetacoplan 💬 Pegcetacoplan [4]  2 , 61, 62, 222 💬
2 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] CASP9 💬 Rimiducid 💬 Rimiducid [6] 19, 60, 65, 284, 285, 326 💬
3 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] CCR4 💬 Mogamulizumab 💬 Mogamulizumab [1] 26 💬
4 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] CCR5 💬 Cenicriviroc 💬 Cenicriviroc [1] 94 💬
5 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] CCR5 💬 Maraviroc 💬 Maraviroc [2] 46, 84 💬
6 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] CD86 💬 Abatacept 💬 Abatacept [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
7 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] CD86 💬 Belatacept 💬 Belatacept [1] 46 💬
8 Kaposi sarcoma-associated herpesvirus infection 💬
 [2] CDK4, CDK6 💬 Abemaciclib 💬 Abemaciclib [1] 34 💬
9 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] CSF2 💬 Otilimab 💬 Otilimab [1] 46 💬
10 Kaposi sarcoma-associated herpesvirus infection 💬
 [13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬 Rontalizumab 💬 Rontalizumab [1] 49 💬
11 Kaposi sarcoma-associated herpesvirus infection 💬
 [13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬 Sifalimumab 💬 Sifalimumab [1] 49 💬
12 Kaposi sarcoma-associated herpesvirus infection 💬
 [2] IFNAR1, IFNAR2 💬 Anifrolumab 💬 Anifrolumab [3] 46, 49, 53 💬
13 Kaposi sarcoma-associated herpesvirus infection 💬
 [2] IFNAR1, IFNAR2 💬 Interferon alfa 💬 Interferon alfa [6] 13, 25, 26, 28, 56, 96 💬
14 Kaposi sarcoma-associated herpesvirus infection 💬
 [2] IFNAR1, IFNAR2 💬 Interferon alfa-2a 💬 Interferon alfa-2a [1] 56 💬
15 Kaposi sarcoma-associated herpesvirus infection 💬
 [2] IFNAR1, IFNAR2 💬 Interferon alfa-2b 💬 Interferon alfa-2b [2] 25, 34 💬
16 Kaposi sarcoma-associated herpesvirus infection 💬
 [2] IFNAR1, IFNAR2 💬 Interferon beta-1a 💬 Interferon beta-1a [4] 13, 26, 96, 97 💬
17 Kaposi sarcoma-associated herpesvirus infection 💬
 [2] IFNAR1, IFNAR2 💬 Interferon beta-1b 💬 Interferon beta-1b [1] 13 💬
18 Kaposi sarcoma-associated herpesvirus infection 💬
 [2] IFNAR1, IFNAR2 💬 Peginterferon beta-1a 💬 Peginterferon beta-1a [1] 13 💬
19 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] IFNGR1 💬 Interferon gamma-1b 💬 Interferon gamma-1b [7] 18, 65, 85, 228, 299, 301, 326 💬
20 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] IL6 💬 Olokizumab 💬 Olokizumab [2] 46, 96 💬
21 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] IL6 💬 Pirfenidone 💬 Pirfenidone [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
22 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] IL6 💬 Pomalidomide 💬 Pomalidomide [5] 28, 51, 85, 227, 331 💬
23 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] IL6 💬 Siltuximab 💬 Siltuximab [2] 28, 331 💬
24 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] IL6 💬 Sirukumab 💬 Sirukumab [2] 41, 46 💬
25 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] JAK1 💬 Abrocitinib 💬 Abrocitinib [1] 84 💬
26 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] JAK1 💬 Filgotinib 💬 Filgotinib [6] 46, 53, 96, 97, 222, 271 💬
27 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] JAK1 💬 Itacitinib 💬 Itacitinib [4] 46, 51, 97, 228 💬
28 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] JAK1 💬 Upadacitinib 💬 Upadacitinib [8] 40, 41, 46, 49, 96, 97, 107, 271 💬
29 Kaposi sarcoma-associated herpesvirus infection 💬
 [2] JAK1, JAK2 💬 Baricitinib 💬 Baricitinib [13]  2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
30 Kaposi sarcoma-associated herpesvirus infection 💬
 [2] JAK1, JAK2 💬 Peficitinib 💬 Peficitinib [1] 46 💬
31 Kaposi sarcoma-associated herpesvirus infection 💬
 [2] JAK1, JAK2 💬 Ruxolitinib 💬 Ruxolitinib [3] 60, 65, 228 💬
32 Kaposi sarcoma-associated herpesvirus infection 💬
 [3] JAK1, JAK2, TYK2 💬 Tofacitinib 💬 Tofacitinib [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬
33 Kaposi sarcoma-associated herpesvirus infection 💬
 [2] MAP2K1, MAP2K2 💬 Binimetinib 💬 Binimetinib [1] 34 💬
34 Kaposi sarcoma-associated herpesvirus infection 💬
 [2] MAP2K1, MAP2K2 💬 Cobimetinib 💬 Cobimetinib [1] 280 💬
35 Kaposi sarcoma-associated herpesvirus infection 💬
 [2] MAP2K1, MAP2K2 💬 Mirdametinib 💬 Mirdametinib [1] 34 💬
36 Kaposi sarcoma-associated herpesvirus infection 💬
 [2] MAP2K1, MAP2K2 💬 Selumetinib 💬 Selumetinib [1] 34 💬
37 Kaposi sarcoma-associated herpesvirus infection 💬
 [2] MAP2K1, MAP2K2 💬 Trametinib 💬 Trametinib [4]  2 , 34, 279, 280 💬
38 Kaposi sarcoma-associated herpesvirus infection 💬
 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 Losmapimod 💬 Losmapimod [2] 113, 222 💬
39 Kaposi sarcoma-associated herpesvirus infection 💬
 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 Neflamapimod 💬 Neflamapimod [1]  8  💬
40 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] MTOR 💬 Everolimus 💬 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
41 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] MTOR 💬 Sirolimus 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
42 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] MTOR 💬 Temsirolimus 💬 Temsirolimus [1] 13 💬
43 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] NFKB1 💬 Iguratimod 💬 Iguratimod [5] 46, 51, 53, 271, 300 💬
44 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] PIK3CA 💬 Alpelisib 💬 Alpelisib [1] 138 💬
45 Kaposi sarcoma-associated herpesvirus infection 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 Leniolisib 💬 Leniolisib [2] 53, 65 💬
46 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] PIK3CD 💬 Parsaclisib 💬 Parsaclisib [3] 35, 53, 61 💬
47 Kaposi sarcoma-associated herpesvirus infection 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Cyclosporine 💬 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
48 Kaposi sarcoma-associated herpesvirus infection 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Pimecrolimus 💬 Pimecrolimus [1] 160 💬
49 Kaposi sarcoma-associated herpesvirus infection 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
50 Kaposi sarcoma-associated herpesvirus infection 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
51 Kaposi sarcoma-associated herpesvirus infection 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Voclosporin 💬 Voclosporin [2] 49, 222 💬
52 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] PTGS2 💬 Aceclofenac 💬 Aceclofenac [1] 46 💬
53 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] PTGS2 💬 Acetaminophen 💬 Acetaminophen [15]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
54 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] PTGS2 💬 Aspirin 💬 Acetylsalicylic acid [14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
55 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] PTGS2 💬 Celecoxib 💬 Celecoxib [10]  2 ,  3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
56 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] PTGS2 💬 Diclofenac 💬 Diclofenac [5] 13, 34, 46, 78, 271 💬
57 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] PTGS2 💬 Diflunisal 💬 Diflunisal [1] 28 💬
58 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] PTGS2 💬 Etodolac 💬 Etodolac [1] 46 💬
59 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] PTGS2 💬 Etoricoxib 💬 Etoricoxib [2] 46, 271 💬
60 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] PTGS2 💬 Flurbiprofen 💬 Flurbiprofen [3] 13, 21, 46 💬
61 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] PTGS2 💬 Ibuprofen 💬 Ibuprofen [7] 13, 46, 65, 107, 113, 271, 299 💬
62 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] PTGS2 💬 Indomethacin 💬 Indomethacin [3] 225, 271, 298 💬
63 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] PTGS2 💬 Ketoprofen 💬 Ketoprofen [1] 46 💬
64 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] PTGS2 💬 Ketorolac 💬 Ketorolac [2] 70, 226 💬
65 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] PTGS2 💬 Loxoprofen 💬 Loxoprofen [2] 46, 271 💬
66 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] PTGS2 💬 Lumiracoxib 💬 Lumiracoxib [1] 46 💬
67 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] PTGS2 💬 Meloxicam 💬 Meloxicam [4] 46, 49, 271, 296 💬
68 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] PTGS2 💬 Naproxen 💬 Naproxen [4] 13, 46, 107, 271 💬
69 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] PTGS2 💬 Nimesulide 💬 Nimesulide [1] 46 💬
70 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] PTGS2 💬 Parecoxib 💬 Parecoxib [2] 46, 271 💬
71 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] PTGS2 💬 Rofecoxib 💬 Rofecoxib [1] 46 💬
72 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] PTGS2 💬 Salsalate 💬 Salsalate [1]  5  💬
73 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] PTGS2 💬 Sulindac 💬 Sulindac [1] 206 💬
74 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] PTGS2 💬 Tolfenamic acid 💬 Tolfenamic acid [1]  5  💬
75 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] PTGS2 💬 Valdecoxib 💬 Valdecoxib [1] 46 💬
76 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
77 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬
78 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
79 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
80 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
81 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
82 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] SYK 💬 Fostamatinib 💬 Fostamatinib [4] 46, 49, 61, 66 💬
83 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] TYK2 💬 Deucravacitinib 💬 Deucravacitinib [3] 49, 96, 97 💬
84 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] VEGFA 💬 Aflibercept 💬 Aflibercept [2] 90, 166 💬
85 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] VEGFA 💬 Bevacizumab 💬 Bevacizumab [6] 13, 34, 85, 87, 227, 280 💬
86 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] VEGFA 💬 Ranibizumab 💬 Ranibizumab [4] 34, 166, 227, 301 💬