Target Gene/Pathway Pathway / Gene
Search results
| No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related  | KEGG GENES | KEGG DRUG | DrugBank | Disease ID | 
|---|---|---|---|---|---|
| 1 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases  | 
BRAF [1] BRAF 💬
 | 
Dabrafenib  Dabrafenib  💬
 | Dabrafenib | 034 [1] 34 💬
 | 
| 2 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases  | 
BRAF [3] BRAF, KDR, RAF1 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 3 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases  | 
EGFR [1] EGFR 💬
 | 
Cetuximab  Cetuximab  💬
 | Cetuximab | 051 [2] 51, 86 💬
 | 
| 4 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases  | 
EGFR [1] EGFR 💬
 | 
Erlotinib  Erlotinib  💬
 | Erlotinib | 094 [1] 94 💬
 | 
| 5 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases  | 
EGFR [1] EGFR 💬
 | 
Gefitinib  Gefitinib  💬
 | Gefitinib | 075 [1] 75 💬
 | 
| 6 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases  | 
EGFR [1] EGFR 💬
 | 
Icotinib Icotinib 💬
 | Icotinib | 034 [1] 34 💬
 | 
| 7 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases  | 
EGFR [2] EGFR, ERBB2 💬
 | 
Lapatinib  Lapatinib  💬
 | Lapatinib | 034 [3] 34, 74, 75 💬
 | 
| 8 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases  | 
EGFR [3] EGFR, ERBB2, ERBB4 💬
 | 
Neratinib  Neratinib  💬
 | Neratinib | 034 [1] 34 💬
 | 
| 9 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases  | 
EGFR [3] EGFR, ERBB2, KDR 💬
 | 
Tesevatinib  Tesevatinib  💬
 | Tesevatinib | 067 [1] 67 💬
 | 
| 10 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases  | 
ESR1 [1] ESR1 💬
 | 
Clomifene  Clomifene  💬
 | Clomifene | 074 [1] 74 💬
 | 
| 11 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases  | 
ESR1 [1] ESR1 💬
 | 
Danazol  Danazol  💬
 | Danazol | 060 [5] 60, 63, 64, 65, 285 💬
 | 
| 12 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases  | 
ESR1 [1] ESR1 💬
 | 
Desogestrel  Desogestrel  💬
 | Desogestrel | 230 [1] 230 💬
 | 
| 13 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases  | 
ESR1 [1] ESR1 💬
 | 
Estetrol  Estetrol  💬
 | Estetrol | 053 [1] 53 💬
 | 
| 14 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases  | 
ESR1 [1] ESR1 💬
 | 
Estetrol  Estetrol  💬
 | Estetrol | 053 [1] 53 💬
 | 
| 15 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases  | 
ESR1 [1] ESR1 💬
 | 
Estradiol  Estradiol  💬
 | Estradiol | 013 [7] 13, 46, 49, 65, 76, 226, 299 💬
 | 
| 16 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases  | 
ESR1 [1] ESR1 💬
 | 
Estradiol valerate  Estradiol valerate  💬
 | Estradiol valerate | 065 [1] 65 💬
 | 
| 17 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases  | 
ESR1 [1] ESR1 💬
 | 
Estriol  Estriol  💬
 | Estriol | 013 [2] 13, 227 💬
 | 
| 18 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases  | 
ESR1 [1] ESR1 💬
 | 
Estriol tripropionate  Estriol tripropionate  💬
 | Estriol | 013 [2] 13, 227 💬
 | 
| 19 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases  | 
ESR1 [1] ESR1 💬
 | 
Ethinyl estradiol  Ethinyl estradiol  💬
 | Ethinylestradiol | 013 [4] 13, 46, 49, 299 💬
 | 
| 20 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases  | 
ESR1 [1] ESR1 💬
 | 
Fulvestrant  Fulvestrant  💬
 | Fulvestrant | 049 [2] 49, 86 💬
 | 
| 21 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases  | 
ESR1 [1] ESR1 💬
 | 
Mestranol  Mestranol  💬
 | Mestranol | 046 [2] 46, 49 💬
 | 
| 22 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases  | 
ESR1 [1] ESR1 💬
 | 
Prasterone  Prasterone  💬
 | Prasterone | 049 [6] 49, 53, 83, 86, 96, 113 💬
 | 
| 23 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases  | 
ESR1 [1] ESR1 💬
 | 
Raloxifene  Raloxifene  💬
 | Raloxifene | 046 [1] 46 💬
 | 
| 24 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases  | 
ESR1 [1] ESR1 💬
 | 
Tamoxifen  Tamoxifen  💬
 | Tamoxifen | 002 [3]  2 , 113, 227 💬
 | 
| 25 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases  | 
FGFR1 [1] FGFR1 💬
 | 
Infigratinib  Infigratinib  💬
 | Infigratinib | 276 [1] 276 💬
 | 
| 26 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases  | 
FGFR1 [2] FGFR1, KDR 💬
 | 
Nintedanib  Nintedanib  💬
 | Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬
 | 
| 27 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases  | 
IGF1R [1] IGF1R 💬
 | 
Linsitinib  Linsitinib  💬
 | Linsitinib | 232 [1] 232 💬
 | 
| 28 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases  | 
IGF1R [1] IGF1R 💬
 | 
Mecasermin  Mecasermin  💬
 | Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬
 | 
| 29 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases  | 
IGF1R [1] IGF1R 💬
 | 
Teprotumumab  Teprotumumab  💬
 | Teprotumumab | 051 [1] 51 💬
 | 
| 30 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases  | 
IL12B [1] IL12B 💬
 | 
Ustekinumab  Ustekinumab  💬
 | Ustekinumab | 037 [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
 | 
| 31 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases  | 
KDR [1] KDR 💬
 | 
Axitinib  Axitinib  💬
 | Axitinib | 034 [1] 34 💬
 | 
| 32 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases  | 
KDR [1] KDR 💬
 | 
Cediranib  Cediranib  💬
 | Cediranib | 034 [1] 34 💬
 | 
| 33 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases  | 
KDR [1] KDR 💬
 | 
Sunitinib  Sunitinib  💬
 | Sunitinib | 028 [2] 28, 34 💬
 | 
| 34 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases  | 
KDR [2] KDR, MET 💬
 | 
Cabozantinib  Cabozantinib  💬
 | Cabozantinib | 034 [1] 34 💬
 | 
| 35 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases  | 
MAP2K1 [2] MAP2K1, MAP2K2 💬
 | 
Binimetinib  Binimetinib  💬
 | Binimetinib | 034 [1] 34 💬
 | 
| 36 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases  | 
MAP2K1 [2] MAP2K1, MAP2K2 💬
 | 
Cobimetinib  Cobimetinib  💬
 | Cobimetinib | 280 [1] 280 💬
 | 
| 37 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases  | 
MAP2K1 [2] MAP2K1, MAP2K2 💬
 | 
Mirdametinib  Mirdametinib  💬
 | Mirdametinib | 034 [1] 34 💬
 | 
| 38 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases  | 
MAP2K1 [2] MAP2K1, MAP2K2 💬
 | 
Selumetinib  Selumetinib  💬
 | Selumetinib | 034 [1] 34 💬
 | 
| 39 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases  | 
MAP2K1 [2] MAP2K1, MAP2K2 💬
 | 
Trametinib  Trametinib  💬
 | Trametinib | 002 [4]  2 , 34, 279, 280 💬
 | 
| 40 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases  | 
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
 | 
Losmapimod  Losmapimod  💬
 | Losmapimod | 113 [2] 113, 222 💬
 | 
| 41 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases  | 
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
 | 
Neflamapimod  Neflamapimod  💬
 | Neflamapimod | 008 [1]  8  💬
 | 
| 42 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases  | 
MTOR [1] MTOR 💬
 | 
Everolimus  Everolimus  💬
 | Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
 | 
| 43 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases  | 
MTOR [1] MTOR 💬
 | 
Sirolimus  Sirolimus  💬
 | Sirolimus | 002 [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
 | 
| 44 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases  | 
MTOR [1] MTOR 💬
 | 
Temsirolimus  Temsirolimus  💬
 | Temsirolimus | 013 [1] 13 💬
 | 
| 45 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases  | 
PIK3CA [1] PIK3CA 💬
 | 
Alpelisib  Alpelisib  💬
 | Alpelisib | 138 [1] 138 💬
 | 
| 46 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases  | 
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬
 | 
Leniolisib  Leniolisib  💬
 | Leniolisib | 053 [2] 53, 65 💬
 | 
| 47 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases  | 
PIK3CD [1] PIK3CD 💬
 | 
Parsaclisib  Parsaclisib  💬
 | Parsaclisib | 035 [3] 35, 53, 61 💬
 | 
| 48 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases  | 
PRKCB [1] PRKCB 💬
 | 
Enzastaurin  Enzastaurin  💬
 | Enzastaurin | 168 [1] 168 💬
 | 
| 49 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases  | 
ROCK1 [2] ROCK1, ROCK2 💬
 | 
Fasudil  Fasudil  💬
 | Fasudil | 002 [4]  2 ,  5 ,  7 , 51 💬
 | 
| 50 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases  | 
ROCK2 [1] ROCK2 💬
 | 
Belumosudil  Belumosudil  💬
 | Belumosudil | 051 [2] 51, 85 💬
 | 
| 51 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases  | 
SMO [1] SMO 💬
 | 
Taladegib  Taladegib  💬
 | Taladegib | 085 [1] 85 💬
 | 
| 52 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases  | 
SMO [1] SMO 💬
 | 
Vismodegib  Vismodegib  💬
 | Vismodegib | 085 [1] 85 💬
 | 
| 53 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases  | 
SRC [1] SRC 💬
 | 
Bosutinib  Bosutinib  💬
 | Bosutinib | 002 [2]  2 , 67 💬
 | 
| 54 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases  | 
SRC [1] SRC 💬
 | 
Dasatinib  Dasatinib  💬
 | Dasatinib | 051 [2] 51, 85 💬
 | 
| 55 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases  | 
SRC [1] SRC 💬
 | 
Dasatinib  Dasatinib  💬
 | Dasatinib | 051 [2] 51, 85 💬
 | 
| 56 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases  | 
SRC [1] SRC 💬
 | 
Saracatinib  Saracatinib  💬
 | Saracatinib | 006 [3]  6 , 89, 272 💬
 | 
| 57 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases  | 
TGFB1 [2] TGFB1, TGFB2 💬
 | 
Fresolimumab  Fresolimumab  💬
 | Fresolimumab | 051 [3] 51, 85, 222 💬
 | 
| 58 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases  | 
TNF [1] TNF 💬
 | 
Adalimumab  Adalimumab  💬
 | Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
 | 
| 59 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases  | 
TNF [1] TNF 💬
 | 
Certolizumab pegol  Certolizumab pegol  💬
 | Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
 | 
| 60 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases  | 
TNF [1] TNF 💬
 | 
Etanercept  Etanercept  💬
 | Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
 | 
| 61 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases  | 
TNF [1] TNF 💬
 | 
Golimumab  Golimumab  💬
 | Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
 | 
| 62 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases  | 
TNF [1] TNF 💬
 | 
Infliximab  Infliximab  💬
 | Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
 | 
| 63 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases  | 
TNF [1] TNF 💬
 | 
Lenalidomide  Lenalidomide  💬
 | Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
 | 
| 64 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases  | 
TNF [1] TNF 💬
 | 
Ozoralizumab  Ozoralizumab  💬
 | Ozoralizumab | 046 [1] 46 💬
 | 
| 65 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases  | 
TNF [1] TNF 💬
 | 
Pegsunercept  Pegsunercept  💬
 | Pegsunercept | 046 [1] 46 💬
 | 
| 66 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases  | 
TNF [1] TNF 💬
 | 
Pirfenidone  Pirfenidone  💬
 | Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
 | 
| 67 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases  | 
TNF [1] TNF 💬
 | 
Pomalidomide  Pomalidomide  💬
 | Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
 | 
| 68 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases  | 
TNF [1] TNF 💬
 | 
Thalidomide  Thalidomide  💬
 | Thalidomide | 002 [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
 | 
| 69 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases  | 
VEGFA [1] VEGFA 💬
 | 
Aflibercept  Aflibercept  💬
 | Aflibercept | 090 [2] 90, 166 💬
 | 
| 70 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases  | 
VEGFA [1] VEGFA 💬
 | 
Bevacizumab  Bevacizumab  💬
 | Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬
 | 
| 71 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases  | 
VEGFA [1] VEGFA 💬
 | 
Ranibizumab  Ranibizumab  💬
 | Ranibizumab | 034 [4] 34, 166, 227, 301 💬
 |