Target Gene/Pathway Pathway / Gene

Search results

No.

KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related

1

Chronic myeloid leukemia 💬

[1] ABL1 💬

[2] 2 , 67 💬

2

Chronic myeloid leukemia 💬

[1] ABL1 💬

[2] 51, 85 💬

3

Chronic myeloid leukemia 💬

[1] ABL1 💬

[2] 51, 85 💬

4

Chronic myeloid leukemia 💬

[1] ABL1 💬

[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬

Disease ID	Name
13	Multiple sclerosis/Neuromyelitis optica;
28	Systemic amyloidosis;AL amyloidosis;
34	Neurofibromatosis;
35	Pemphigus;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
51	Scleroderma;Systemic sclerosis;SSc;
85	Idiopathic interstitial pneumonia;IIPs;
86	Pulmonary arterial hypertension;PAH;
87	Pulmonary veno-occlusive disease;Pulmonary capillary hemangiomatosis;
88	Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;
89	Lymphangioleiomyomatosis;LAM;
162	Pemphigoid;

5

Chronic myeloid leukemia 💬

[1] ABL1 💬

[5] 6 , 8 , 34, 51, 86 💬

6

Chronic myeloid leukemia 💬

[1] ABL1 💬

Saracatinib 💬

[3] 6 , 89, 272 💬

7

Chronic myeloid leukemia 💬

[1] BRAF 💬

Dabrafenib 💬

[1] 34 💬

8

Chronic myeloid leukemia 💬

[2] BRAF, RAF1 💬

[2] 34, 86 💬

9

Chronic myeloid leukemia 💬

[2] CDK4, CDK6 💬

Abemaciclib 💬

[1] 34 💬

10

Chronic myeloid leukemia 💬

[2] HDAC1, HDAC2 💬

Vorinostat 💬

[2] 75, 96 💬

11

Chronic myeloid leukemia 💬

[2] MAP2K1, MAP2K2 💬

Binimetinib 💬

[1] 34 💬

12

Chronic myeloid leukemia 💬

[2] MAP2K1, MAP2K2 💬

Cobimetinib 💬

[1] 280 💬

13

Chronic myeloid leukemia 💬

[2] MAP2K1, MAP2K2 💬

Mirdametinib 💬

[1] 34 💬

14

Chronic myeloid leukemia 💬

[2] MAP2K1, MAP2K2 💬

Selumetinib 💬

[1] 34 💬

15

Chronic myeloid leukemia 💬

[2] MAP2K1, MAP2K2 💬

Trametinib 💬

[4] 2 , 34, 279, 280 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
34	Neurofibromatosis;
279	Huge venous malformation with cervical, oral and pharyngeal diffuse lesion;Huge venous malformation;Venous malformation;
280	Huge arteriovenous malformation with cervicofacial or limb lesion;Huge arteriovenous malformation;Arteriovenous malformation;

16

Chronic myeloid leukemia 💬

[1] NFKB1 💬

Iguratimod 💬

[5] 46, 51, 53, 271, 300 💬

Disease ID	Name
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
51	Scleroderma;Systemic sclerosis;SSc;
53	Sjogren syndrome;Sjögren syndrome;Syndrome Sjogren's;SS;Autoimmune exocrinopathy;
271	Ankylosing spondylitis;Spondylarthritis ankylopoietica;
300	IgG4-related disease;

17

Chronic myeloid leukemia 💬

[1] PIK3CA 💬

[1] 138 💬

18

Chronic myeloid leukemia 💬

[3] PIK3CA, PIK3CB, PIK3CD 💬

Name	Full Name
PIK3CA	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
PIK3CB	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
PIK3CD	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta

Leniolisib 💬

[2] 53, 65 💬

19

Chronic myeloid leukemia 💬

[1] PIK3CD 💬

Parsaclisib 💬

[3] 35, 53, 61 💬

20

Chronic myeloid leukemia 💬

[1] RELA 💬

Edasalonexent 💬

[1] 113 💬

21

Chronic myeloid leukemia 💬

[3] TGFB1, TGFB2, TGFB3 💬

Fresolimumab 💬

[3] 51, 85, 222 💬