Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Autoimmune thyroid disease 💬
 [1] CD40 💬 Bleselumab 💬 Bleselumab [1] 222 💬
2 Autoimmune thyroid disease 💬
 [1] CD40 💬 Iscalimab 💬 Iscalimab [2] 49, 53 💬
3 Autoimmune thyroid disease 💬
 [1] CD40 💬 Ravagalimab 💬 Ravagalimab [2] 53, 97 💬
4 Autoimmune thyroid disease 💬
 [1] CD40LG 💬 Toralizumab 💬 Toralizumab [1] 63 💬
5 Autoimmune thyroid disease 💬
 [2] CD80, CD86 💬 Abatacept 💬 Abatacept [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
6 Autoimmune thyroid disease 💬
 [2] CD80, CD86 💬 Belatacept 💬 Belatacept [1] 46 💬
7 Autoimmune thyroid disease 💬
 [1] CTLA4 💬 Ipilimumab 💬 Ipilimumab [1] 159 💬
8 Autoimmune thyroid disease 💬
 [1] CTLA4 💬 Tremelimumab 💬 Tremelimumab [1] 96 💬
9 Autoimmune thyroid disease 💬
 [13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬 Rontalizumab 💬 Rontalizumab [1] 49 💬
10 Autoimmune thyroid disease 💬
 [13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬 Sifalimumab 💬 Sifalimumab [1] 49 💬
11 Autoimmune thyroid disease 💬
 [1] IL10 💬 Pirfenidone 💬 Pirfenidone [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
12 Autoimmune thyroid disease 💬
 [1] IL4 💬 Binetrakin 💬 Binetrakin [1] 46 💬
13 Autoimmune thyroid disease 💬
 [1] IL5 💬 Mepolizumab 💬 Mepolizumab [4] 44, 45, 98, 162 💬
14 Autoimmune thyroid disease 💬
 [1] IL5 💬 Reslizumab 💬 Reslizumab [2] 44, 98 💬
15 Autoimmune thyroid disease 💬
 [1] TPO 💬 Methimazole 💬 Methimazole [1] 50 💬