Gene

Disease ID	Name
11	Myasthenia gravis;MG;
13	Multiple sclerosis/Neuromyelitis optica;
14	Chronic inflammatory demyelinating polyneuropathy;Chronic inflammatory demyelinating poly (radiculo) neuropathy;CIDP;Multifocal motor neuropathy;
61	Autoimmune hemolytic anemia;AIHA;
62	Paroxysmal nocturnal hemoglobinuria;PNH;
109	Atypical hemolytic uremic syndrome;aHUS;
222	Primary nephrotic syndrome;

Systemic lupus erythematosus 💬

[1] C5 💬

Nomacopan 💬

Nomacopan

[3] 62, 109, 162 💬

Systemic lupus erythematosus 💬

[1] C5 💬

Pozelimab 💬

Pozelimab

[2] 11, 62 💬

Systemic lupus erythematosus 💬

[1] C5 💬

Ravulizumab 💬

Ravulizumab

[7] 2 , 11, 13, 50, 62, 66, 109 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
11	Myasthenia gravis;MG;
13	Multiple sclerosis/Neuromyelitis optica;
50	Dermatomyositis;Polymyositis;
62	Paroxysmal nocturnal hemoglobinuria;PNH;
66	IgA nephropathy;IgA nephritis;Berger disease;IgA-IgG nephropathy;
109	Atypical hemolytic uremic syndrome;aHUS;

Systemic lupus erythematosus 💬

[1] C5 💬

Vilobelimab 💬

Vilobelimab

[3] 43, 44, 269 💬

Disease ID	Name
43	Microscopic polyangiitis;MPA;
44	Wegener granulomatosis;Multiple vasculitis granulomatous disease;Granulomatosis with polyangiitis;
269	Pyogenic arthritis;Pyoderma gangrenosum;Acne syndrome;PAPA syndrome;

Systemic lupus erythematosus 💬

[1] C5 💬

Zilucoplan 💬

Zilucoplan

[3] 2 , 11, 62 💬

Systemic lupus erythematosus 💬

[1] CD40 💬

Bleselumab 💬

Bleselumab

[1] 222 💬

Systemic lupus erythematosus 💬

[1] CD40 💬

Iscalimab 💬

Iscalimab

[2] 49, 53 💬

Systemic lupus erythematosus 💬

[1] CD40 💬

Ravagalimab 💬

Ravagalimab

[2] 53, 97 💬

Systemic lupus erythematosus 💬

[1] CD40LG 💬

Toralizumab 💬

Toralizumab

[1] 63 💬

Systemic lupus erythematosus 💬

[2] CD80, CD86 💬

Abatacept 💬

Abatacept

[26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬

Disease ID	Name
11	Myasthenia gravis;MG;
13	Multiple sclerosis/Neuromyelitis optica;
19	Lysosomal storage disease;Lysosomal disease;
41	Giant cell arteritis;Temporal arteritis;
44	Wegener granulomatosis;Multiple vasculitis granulomatous disease;Granulomatosis with polyangiitis;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
49	Systemic lupus erythematosus;SLE;
50	Dermatomyositis;Polymyositis;
51	Scleroderma;Systemic sclerosis;SSc;
53	Sjogren syndrome;Sjögren syndrome;Syndrome Sjogren's;SS;Autoimmune exocrinopathy;
55	Relapsing polychondritis;
60	Aplastic anemia;
65	Primary immunodeficiency;
84	Sarcoidosis;
93	Primary biliary cholangitis;Primary biliary cirrhosis;PBC;
95	Autoimmune hepatitis;
96	Crohn disease;Terminal ileitis;
97	Ulcerative colitis;
107	Juvenile idiopathic arthritis;JIA;
160	Congenital ichthyosis;
164	Oculocutaneous albinism;
222	Primary nephrotic syndrome;
271	Ankylosing spondylitis;Spondylarthritis ankylopoietica;
284	Diamond-Blackfan anemia;
285	Fanconi anemia;
300	IgG4-related disease;

Systemic lupus erythematosus 💬

[2] CD80, CD86 💬

Belatacept 💬

Belatacept

[1] 46 💬

Systemic lupus erythematosus 💬

[1] ELANE 💬

Sivelestat 💬

Sivelestat

[3] 13, 85, 96 💬

Systemic lupus erythematosus 💬

[2] GRIN2A, GRIN2B 💬

Acamprosate 💬

Acamprosate

[2] 6 , 206 💬

Systemic lupus erythematosus 💬

[2] GRIN2A, GRIN2B 💬

Amantadine 💬

Amantadine

[4] 6 , 8 , 13, 127 💬

Systemic lupus erythematosus 💬

[2] GRIN2A, GRIN2B 💬

Dextromethorphan 💬

Dextromethorphan

[11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
6	Parkinson disease;Disease Parkinson's;
8	Huntington disease;Huntington chorea;
13	Multiple sclerosis/Neuromyelitis optica;
21	Mitochondrial disease;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
78	Hypopituitarism;Anterior pituitary hypothyroidism;
85	Idiopathic interstitial pneumonia;IIPs;
96	Crohn disease;Terminal ileitis;
97	Ulcerative colitis;
156	Rett syndrome;

Systemic lupus erythematosus 💬

[2] GRIN2A, GRIN2B 💬

Esketamine 💬

Esketamine

[3] 2 , 4 , 70 💬

Systemic lupus erythematosus 💬

[2] GRIN2A, GRIN2B 💬

Ketamine 💬

Ketamine

[8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
4	Primary lateral sclerosis;PLS;
6	Parkinson disease;Disease Parkinson's;
13	Multiple sclerosis/Neuromyelitis optica;
70	Spinal stenosis;Extensive spinal canal stenosis;
113	Muscular dystrophy;
156	Rett syndrome;
215	Tetralogy of Fallot;Fallot tetralogy;

Systemic lupus erythematosus 💬

[2] GRIN2A, GRIN2B 💬

Latrepirdine 💬

Latrepirdine

[1] 8 💬

Systemic lupus erythematosus 💬

[2] GRIN2A, GRIN2B 💬

Memantine 💬

Memantine

[8] 2 , 6 , 8 , 13, 49, 127, 205, 206 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
6	Parkinson disease;Disease Parkinson's;
8	Huntington disease;Huntington chorea;
13	Multiple sclerosis/Neuromyelitis optica;
49	Systemic lupus erythematosus;SLE;
127	Frontotemporal lobar degeneration;
205	Fragile X syndrome related disease;Fragile X-associated tremor/ataxia syndrome;FXTAS;
206	Fragile X syndrome;

Systemic lupus erythematosus 💬

[2] GRIN2A, GRIN2B 💬

Riluzole 💬

Riluzole

[9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
3	Spinal muscular atrophy;Myelopathic muscular atrophy;
5	Progressive supranuclear palsy;PSP;
8	Huntington disease;Huntington chorea;
13	Multiple sclerosis/Neuromyelitis optica;
17	Multiple system atrophy;MSA-C;MSA-P;
18	Spinocerebellar degeneration;SCD;
203	22q11.2 deletion syndrome;
206	Fragile X syndrome;

Systemic lupus erythematosus 💬

[1] IFNG 💬

Emapalumab 💬

Emapalumab

[3] 49, 65, 107 💬

Systemic lupus erythematosus 💬

[1] IFNG 💬

Fontolizumab 💬

Fontolizumab

[1] 46 💬

Systemic lupus erythematosus 💬

[2] IL10, TNF 💬

Pirfenidone 💬

Pirfenidone

[11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬

Disease ID	Name
13	Multiple sclerosis/Neuromyelitis optica;
34	Neurofibromatosis;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
50	Dermatomyositis;Polymyositis;
51	Scleroderma;Systemic sclerosis;SSc;
58	Hypertrophic cardiomyopathy;HCM;
84	Sarcoidosis;
85	Idiopathic interstitial pneumonia;IIPs;
164	Oculocutaneous albinism;
222	Primary nephrotic syndrome;
228	Bronchiolitis obliterans;Obliterating bronchiolitis;

Systemic lupus erythematosus 💬

[1] TNF 💬

Adalimumab 💬

Name

Other Names

Adalimumab

Adalimumab (USAN/INN)
Adalimumab (genetical recombination) (JAN)
Adalimumab (genetical recombination) [Adalimumab biosimilar 1] (JAN)
Adalimumab (genetical recombination) [Adalimumab biosimilar 2] (JAN)
Adalimumab (genetical recombination) [Adalimumab biosimilar 3] (JAN)
Adalimumab-adaz
Adalimumab-adbm
Adalimumab-afzb
Adalimumab-atto
Adalimumab-bwwd
Adalimumab-fkjp
Humira (TN)
Abrilada (TN)
Amjevita (TN)
Cyltezo (TN)
Hadlima (TN)
Hyrimoz (TN)

Adalimumab

[17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬

Disease ID	Name
19	Lysosomal storage disease;Lysosomal disease;
37	Generalised pustular psoriasis;Pustular psoriasis;
40	Takayasu arteritis;Aortitis syndrome;Pulseless disease;Aortitis syndrome;
41	Giant cell arteritis;Temporal arteritis;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
56	Behcet disease;Behçet disease;BD;
84	Sarcoidosis;
96	Crohn disease;Terminal ileitis;
97	Ulcerative colitis;
107	Juvenile idiopathic arthritis;JIA;
160	Congenital ichthyosis;
164	Oculocutaneous albinism;
222	Primary nephrotic syndrome;
226	Interstitial cystitis with Hunners ulcer;Interstitial cystitis;
269	Pyogenic arthritis;Pyoderma gangrenosum;Acne syndrome;PAPA syndrome;
270	Chronic recurrent multifocal osteomyelitis;
271	Ankylosing spondylitis;Spondylarthritis ankylopoietica;

Systemic lupus erythematosus 💬

[1] TNF 💬

Certolizumab pegol 💬

Certolizumab pegol

[8] 37, 46, 49, 96, 97, 107, 226, 271 💬

Disease ID	Name
37	Generalised pustular psoriasis;Pustular psoriasis;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
49	Systemic lupus erythematosus;SLE;
96	Crohn disease;Terminal ileitis;
97	Ulcerative colitis;
107	Juvenile idiopathic arthritis;JIA;
226	Interstitial cystitis with Hunners ulcer;Interstitial cystitis;
271	Ankylosing spondylitis;Spondylarthritis ankylopoietica;

Systemic lupus erythematosus 💬

[1] TNF 💬

Etanercept 💬

Name	Other Names
Etanercept	Etanercept (USAN/INN) Etanercept (genetical recombination) (JAN) Etanercept (genetical recombination) [Etanercept biosimilar 1] (JAN) Etanercept (genetical recombination) [Etanercept biosimilar 2] (JAN) Enbrel (TN)

Etanercept

[16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬

Disease ID	Name
15	Inclusion body myositis;
28	Systemic amyloidosis;AL amyloidosis;
35	Pemphigus;
38	Stevens-Johnson syndrome;SJS;Mucocutaneous ocular syndrome;
39	Toxic epidermal necrolysis;Toxic epidermal necrosis;TEN;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
50	Dermatomyositis;Polymyositis;
53	Sjogren syndrome;Sjögren syndrome;Syndrome Sjogren's;SS;Autoimmune exocrinopathy;
56	Behcet disease;Behçet disease;BD;
60	Aplastic anemia;
85	Idiopathic interstitial pneumonia;IIPs;
107	Juvenile idiopathic arthritis;JIA;
228	Bronchiolitis obliterans;Obliterating bronchiolitis;
270	Chronic recurrent multifocal osteomyelitis;
271	Ankylosing spondylitis;Spondylarthritis ankylopoietica;
285	Fanconi anemia;

Systemic lupus erythematosus 💬

[1] TNF 💬

Golimumab 💬

Golimumab

[8] 46, 56, 84, 96, 97, 107, 270, 271 💬

Disease ID	Name
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
56	Behcet disease;Behçet disease;BD;
84	Sarcoidosis;
96	Crohn disease;Terminal ileitis;
97	Ulcerative colitis;
107	Juvenile idiopathic arthritis;JIA;
270	Chronic recurrent multifocal osteomyelitis;
271	Ankylosing spondylitis;Spondylarthritis ankylopoietica;

Systemic lupus erythematosus 💬

[1] TNF 💬

Infliximab 💬

Name	Other Names
Infliximab	Infliximab (USAN/INN) Infliximab (genetical recombination) (JAN) Infliximab (genetical recombination) [Infliximab biosimilar 1] (JAN) Infliximab (genetical recombination) [Infliximab biosimilar 2] (JAN) Infliximab (genetical recombination) [Infliximab biosimilar 3] (JAN) Infliximab-dyyb Infliximab-abda Infliximab-axxq Remicade (TN) Inflectra (TN) Renflexis (TN) Avsola (TN)

Infliximab

[27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬

Disease ID	Name
35	Pemphigus;
37	Generalised pustular psoriasis;Pustular psoriasis;
38	Stevens-Johnson syndrome;SJS;Mucocutaneous ocular syndrome;
39	Toxic epidermal necrolysis;Toxic epidermal necrosis;TEN;
40	Takayasu arteritis;Aortitis syndrome;Pulseless disease;Aortitis syndrome;
41	Giant cell arteritis;Temporal arteritis;
42	Polyarteritis nodosa;PAN;
43	Microscopic polyangiitis;MPA;
45	Eosinophilic granulomatosis with Polyangiitis;EGPA;Eosinophilic multiple vasculitis granulomatous disease;Allergic granulomatous angiitis;AGA;Churg-Strauss syndrome;CSS;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
49	Systemic lupus erythematosus;SLE;
50	Dermatomyositis;Polymyositis;
55	Relapsing polychondritis;
56	Behcet disease;Behçet disease;BD;
65	Primary immunodeficiency;
84	Sarcoidosis;
85	Idiopathic interstitial pneumonia;IIPs;
95	Autoimmune hepatitis;
96	Crohn disease;Terminal ileitis;
97	Ulcerative colitis;
98	Eosinophilic gastrointestinal disease;Eosinophilic gastroenteritis;Eosinophilic esophagitis;Eosinophilic colitis;Eosinophilic gastro-intestinal disorder;EGID;
107	Juvenile idiopathic arthritis;JIA;
162	Pemphigoid;
164	Oculocutaneous albinism;
269	Pyogenic arthritis;Pyoderma gangrenosum;Acne syndrome;PAPA syndrome;
270	Chronic recurrent multifocal osteomyelitis;
271	Ankylosing spondylitis;Spondylarthritis ankylopoietica;

Systemic lupus erythematosus 💬

[1] TNF 💬

Lenalidomide 💬

Lenalidomide

[8] 16, 26, 28, 34, 49, 284, 300, 331 💬

Disease ID	Name
16	Crow-Fukase syndrome;POEMS syndrome;
26	HTLV-1-associated myelopathy;Tropical spastic paraparesis;HTLV-1;HTLV-I-associated myelopathy;HAM;
28	Systemic amyloidosis;AL amyloidosis;
34	Neurofibromatosis;
49	Systemic lupus erythematosus;SLE;
284	Diamond-Blackfan anemia;
300	IgG4-related disease;
331	Idiopathic multicentric castleman disease;iMCD;Castleman disease;

Systemic lupus erythematosus 💬

[1] TNF 💬

Ozoralizumab 💬

Ozoralizumab

[1] 46 💬

Systemic lupus erythematosus 💬

[1] TNF 💬

Pegsunercept 💬

Pegsunercept

[1] 46 💬

Systemic lupus erythematosus 💬

[1] TNF 💬

Pomalidomide 💬

Pomalidomide

[5] 28, 51, 85, 227, 331 💬

Disease ID	Name
28	Systemic amyloidosis;AL amyloidosis;
51	Scleroderma;Systemic sclerosis;SSc;
85	Idiopathic interstitial pneumonia;IIPs;
227	Osler disease;Hereditary hemorrhagic telangiectasia;Osler-Weber-Rendu disease;
331	Idiopathic multicentric castleman disease;iMCD;Castleman disease;

Systemic lupus erythematosus 💬

[1] TNF 💬

Thalidomide 💬

Thalidomide

[20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
16	Crow-Fukase syndrome;POEMS syndrome;
20	Adrenoleukodystrophy;ALD;
28	Systemic amyloidosis;AL amyloidosis;
49	Systemic lupus erythematosus;SLE;
51	Scleroderma;Systemic sclerosis;SSc;
53	Sjogren syndrome;Sjögren syndrome;Syndrome Sjogren's;SS;Autoimmune exocrinopathy;
56	Behcet disease;Behçet disease;BD;
65	Primary immunodeficiency;
84	Sarcoidosis;
85	Idiopathic interstitial pneumonia;IIPs;
94	Primary sclerosing cholangitis;PSC;
96	Crohn disease;Terminal ileitis;
97	Ulcerative colitis;
227	Osler disease;Hereditary hemorrhagic telangiectasia;Osler-Weber-Rendu disease;
271	Ankylosing spondylitis;Spondylarthritis ankylopoietica;
280	Huge arteriovenous malformation with cervicofacial or limb lesion;Huge arteriovenous malformation;Arteriovenous malformation;
298	Hereditary pancreatitis;Chronic pancreatitis;
300	IgG4-related disease;
331	Idiopathic multicentric castleman disease;iMCD;Castleman disease;