Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 Amiodarone 💬 Amiodarone [2] 28, 127 💬
2 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 Atenolol 💬 Atenolol [1] 167 💬
3 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 Bisoprolol 💬 Bisoprolol [4] 58, 67, 86, 113 💬
4 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 Carvedilol 💬 Carvedilol [4] 57, 86, 113, 210 💬
5 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 Celiprolol 💬 Celiprolol [1] 168 💬
6 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 Dipivefrin 💬 Dipivefrin [1]  6  💬
7 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 Dobutamine 💬 Dobutamine [4] 57, 58, 86, 215 💬
8 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 Droxidopa 💬 Droxidopa [5]  5 ,  6 , 17, 169, 170 💬
9 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 Ephedrine 💬 Ephedrine [1] 11 💬
10 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 Epinephrine 💬 Epinephrine [3] 46, 70, 96 💬
11 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 Esmolol 💬 Esmolol [1] 58 💬
12 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 Metoprolol 💬 Metoprolol [6] 17, 57, 58, 113, 193, 226 💬
13 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 Nadolol 💬 Nadolol [1]  6  💬
14 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 Nebivolol 💬 Nebivolol [4] 17, 85, 113, 167 💬
15 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 Noradrenaline 💬 Norepinephrine [2] 22, 296 💬
16 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 Propranolol 💬 Propranolol [6]  6 , 158, 167, 227, 278, 296 💬
17 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 Pseudoephedrine 💬 Pseudoephedrine [1] 17 💬
18 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 Timolol 💬 Timolol [2] 157, 227 💬
19 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 Timolol 💬 Timolol [2] 157, 227 💬
20 Dilated cardiomyopathy 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Amlodipine 💬 Amlodipine [4] 13, 51, 67, 298 💬
21 Dilated cardiomyopathy 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Cilnidipine 💬 Cilnidipine [1] 67 💬
22 Dilated cardiomyopathy 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Diltiazem 💬 Diltiazem [3] 51, 58, 86 💬
23 Dilated cardiomyopathy 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Isradipine 💬 Isradipine [1]  6  💬
24 Dilated cardiomyopathy 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Nicardipine 💬 Nicardipine [2] 70, 86 💬
25 Dilated cardiomyopathy 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Nifedipine 💬 Nifedipine [2] 50, 81 💬
26 Dilated cardiomyopathy 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Nilvadipine 💬 Nilvadipine [1] 90 💬
27 Dilated cardiomyopathy 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Perhexiline 💬 Perhexiline [2] 58, 272 💬
28 Dilated cardiomyopathy 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Propiverine 💬 Propiverine [1] 226 💬
29 Dilated cardiomyopathy 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Topiramate 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
30 Dilated cardiomyopathy 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Verapamil 💬 Verapamil [4] 58, 96, 140, 167 💬
31 Dilated cardiomyopathy 💬
 [2] CACNA2D1, CACNA2D2 💬 Mirogabalin 💬 Mirogabalin [1] 70 💬
32 Dilated cardiomyopathy 💬
 [4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬 Gabapentin 💬 Gabapentin [5]  6 , 13, 19, 70, 298 💬
33 Dilated cardiomyopathy 💬
 [4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬 Pregabalin 💬 Pregabalin [5] 13, 36, 46, 70, 298 💬
34 Dilated cardiomyopathy 💬
 [1] DMD 💬 Casimersen 💬 Casimersen [1] 113 💬
35 Dilated cardiomyopathy 💬
 [1] DMD 💬 Drisapersen 💬 Drisapersen [1] 113 💬
36 Dilated cardiomyopathy 💬
 [1] DMD 💬 Eteplirsen 💬 Eteplirsen [1] 113 💬
37 Dilated cardiomyopathy 💬
 [1] DMD 💬 Golodirsen 💬 Golodirsen [1] 113 💬
38 Dilated cardiomyopathy 💬
 [1] DMD 💬 Viltolarsen 💬 Viltolarsen [1] 113 💬
39 Dilated cardiomyopathy 💬
 [1] ITGA4 💬 Firategrast 💬 Firategrast [1] 13 💬
40 Dilated cardiomyopathy 💬
 [1] ITGA4 💬 Natalizumab 💬 Natalizumab [6] 13, 15, 25, 46, 63, 96 💬
41 Dilated cardiomyopathy 💬
 [2] ITGA4, ITGB7 💬 Abrilumab 💬 Abrilumab [2] 96, 97 💬
42 Dilated cardiomyopathy 💬
 [2] ITGA4, ITGB7 💬 Vedolizumab 💬 Vedolizumab [3] 94, 96, 97 💬
43 Dilated cardiomyopathy 💬
 [1] ITGB7 💬 Etrolizumab 💬 Etrolizumab [2] 96, 97 💬
44 Dilated cardiomyopathy 💬
 [1] MYH7 💬 Mavacamten 💬 Mavacamten [1] 58 💬
45 Dilated cardiomyopathy 💬
 [3] TGFB1, TGFB2, TGFB3 💬 Fresolimumab 💬 Fresolimumab [3] 51, 85, 222 💬
46 Dilated cardiomyopathy 💬
 [1] TNF 💬 Adalimumab 💬 Adalimumab [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
47 Dilated cardiomyopathy 💬
 [1] TNF 💬 Certolizumab pegol 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
48 Dilated cardiomyopathy 💬
 [1] TNF 💬 Etanercept 💬 Etanercept [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
49 Dilated cardiomyopathy 💬
 [1] TNF 💬 Golimumab 💬 Golimumab [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
50 Dilated cardiomyopathy 💬
 [1] TNF 💬 Infliximab 💬 Infliximab [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
51 Dilated cardiomyopathy 💬
 [1] TNF 💬 Lenalidomide 💬 Lenalidomide [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
52 Dilated cardiomyopathy 💬
 [1] TNF 💬 Ozoralizumab 💬 Ozoralizumab [1] 46 💬
53 Dilated cardiomyopathy 💬
 [1] TNF 💬 Pegsunercept 💬 Pegsunercept [1] 46 💬
54 Dilated cardiomyopathy 💬
 [1] TNF 💬 Pirfenidone 💬 Pirfenidone [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
55 Dilated cardiomyopathy 💬
 [1] TNF 💬 Pomalidomide 💬 Pomalidomide [5] 28, 51, 85, 227, 331 💬
56 Dilated cardiomyopathy 💬
 [1] TNF 💬 Thalidomide 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬