Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank Drug (Description in trials) KEGG GENES KEGG PATHWAY Disease ID
1 Water [1] Water[9] AVONEX; ENBREL; Glucagon; Hiberix; Indocyanine Green; OMNITROPE; Sterile Water for Injection; Water; WATER FOR INJECTION; --[23] 2, 5, 6, 13, 17, 19, 22, 35, 46, 51, 53, 56, 57, 63, 65, 67, 78, 84, 96, 97, 226, 278, 299
2 Serine [1] Serine[2] L-Serine; Serine; --[4] 2, 6, 86, 96
3 Biotin [1] Biotin[4] BIOTIN; Biotina; D-BIOTIN; Vitamin B7; --[5] 2, 8, 10, 13, 20
4 Niacinamide [1] Nicotinamide[4] Ginseng; Multivitamin; Niacinamide; NICOTINAMIDE; --[11] 2, 5, 6, 13, 18, 49, 65, 67, 107, 162, 191
5 Anhydrous lactose [1] Lactose[1] Lactose; --[6] 2, 6, 13, 97, 228, 310
6 Thioctic acid amide [1] Lipoic acid[3] Alpha Lipoic Acid; Alpha-lipoic acid; Lipoic acid; --[5] 2, 5, 13, 14, 20
7 Inosine [1] Inosine[1] Inosine; --[6] 2, 6, 13, 17, 85, 122
8 Levodopa [1] Levodopa[8] DUODOPA; Inbrija; L-DOPA; Levodopa; PARCOPA; SINEMET; SINEMET CR; Stalevo; [5] DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[8] 2, 4, 6, 17, 90, 140, 164, 201
9 Dextran 1 [1] Dextran[1] Dextran; --[5] 2, 62, 79, 96, 97
10 Testosterone [1] Testosterone[1] Testosterone; [1] AR 💬[4] Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬[9] 1, 2, 3, 13, 60, 76, 78, 113, 265
11 Thioctic acid [1] Lipoic acid[3] Alpha Lipoic Acid; Alpha-lipoic acid; Lipoic acid; --[5] 2, 5, 13, 14, 20
12 Tretinoin [1] Tretinoin[5] ATRA; Retinoic acid; Tretinoin; TRETINOINA; VESANOID; [3] PML,
RARA,
RARB 💬		[12] Acute myeloid leukemia, Endocytosis, Estrogen signaling pathway, Gastric cancer, Herpes simplex virus 1 infection, Influenza A, Non-small cell lung cancer, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Transcriptional misregulation in cancer, Ubiquitin mediated proteolysis 💬[6] 2, 62, 63, 75, 94, 231
13 Tacrolimus [1] Tacrolimus[2] Prograf; TACROLIMUS; [5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
14 Atropine [1] Atropine[2] Atropina; Atropine; [5] CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬		[13] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬[2] 2, 299
15 Scopolamine [1] Scopolamine[1] Scopolamine; [5] CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬		[13] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬[1] 2
16 Corticotropin [1] Corticotropin[5] ACTH; Acthar; Adrenocorticotropic Hormone; Corticotrophin; Corticotropin; [1] MC2R 💬[5] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[15] 2, 13, 14, 46, 49, 50, 66, 75, 78, 81, 84, 145, 193, 205, 222
17 Ciprofloxacin [1] Ciprofloxacin[2] CIPROFLOXACIN; CIPROFLOXACIN HYDROCHLORIDE; --[5] 2, 60, 96, 97, 299
18 Ampicillin [1] Ampicillin[1] ABPC; --[5] 2, 6, 13, 84, 299
19 Baclofen [1] Baclofen[2] BACLOFEN; Kemstro; [2] GABBR1,
GABBR2 💬		[7] Estrogen signaling pathway, GABAergic synapse, GnRH secretion, Morphine addiction, Neuroactive ligand-receptor interaction, Taste transduction, cAMP signaling pathway 💬[7] 2, 10, 13, 18, 65, 149, 206
20 Betamethasone [1] Betamethasone[1] Betamethasone; [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[7] 2, 28, 46, 83, 90, 96, 235
21 Capsaicin [1] Capsaicin[2] Capsaicin; Qutenza; [1] TRPV1 💬[2] Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[5] 2, 6, 19, 86, 226
22 Cimetidine [1] Cimetidine[1] Cimetidine; [1] HRH2 💬[3] Calcium signaling pathway, Gastric acid secretion, Neuroactive ligand-receptor interaction 💬[2] 2, 254
23 Dronabinol [1] Dronabinol[4] Delta-9-tetrahydrocannabinol; DRONABINOL; Sativex; Tetrahydrocannabinol; [2] CNR1,
CNR2 💬		[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬[8] 2, 8, 13, 36, 46, 96, 271, 298
24 Enoxacin [1] Enoxacin[1] Enoxacin; --[1] 2
25 Lamivudine [1] Lamivudine[4] COMBIVIR; Epivir; Lamivudine; Triumeq; --[7] 2, 26, 42, 46, 135, 265, 325
26 Valproic acid [1] Valproic acid[3] Valproate; VALPROATE SODIUM; Valproic Acid; [7] ABAT,
ALDH5A1,
CACNA1G,
CACNA1H,
CACNA1I,
GAD1,
GAD2 💬		[17] Alanine, aspartate and glutamate metabolism, Aldosterone synthesis and secretion, Butanoate metabolism, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, GABAergic synapse, GnRH secretion, MAPK signaling pathway, Metabolic pathways, Propanoate metabolism, Taurine and hypotaurine metabolism, Type I diabetes mellitus, Type II diabetes mellitus, Valine, leucine and isoleucine degradation, beta-Alanine metabolism 💬[17] 2, 3, 5, 6, 13, 26, 34, 65, 85, 89, 90, 102, 127, 222, 233, 256, 331
27 Methylprednisolone [1] Methylprednisolone[4] Medrol; Methylprednisolon; Methylprednisolone; Methylprednisolone acetate; [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[48] 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 86, 93, 95, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300
28 Ribavirin [1] Ribavirin[2] Copegus; Ribavirin; --[2] 2, 96
29 Ritonavir [1] Ritonavir[2] Norvir; Ritonavir; --[3] 2, 86, 265
30 Olanzapine [1] Olanzapine[2] Olanzapine; Zyprexa; [11] ADRA1A,
ADRA1B,
ADRA1D,
DRD2,
DRD3,
DRD4,
HRH1,
HTR2A,
HTR2B,
HTR2C,
HTR6 💬		[16] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Salivary secretion, Serotonergic synapse, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 2, 8
31 Prednisone [1] Prednisone[3] Prednisona; Prednisone; RAYOS; [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[48] 2, 6, 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 95, 96, 97, 113, 127, 162, 164, 205, 222, 224, 228, 251, 283, 284, 285, 288, 299, 300, 331
32 Pyrimethamine [1] Pyrimethamine[2] Daraprim; Pyrimethamine; --[11] 2, 4, 6, 13, 19, 46, 51, 65, 96, 97, 265
33 Dexmedetomidine [1] Dexmedetomidine[4] Dexdor; DEXMEDETOMIDINA; Dexmedetomidine; DEXMEDETOMIDINE HYDROCHLORIDE; [3] ADRA2A,
ADRA2B,
ADRA2C 💬		[2] Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[13] 2, 4, 6, 21, 34, 46, 70, 107, 113, 212, 215, 226, 280
34 Cromolyn sodium [1] Cromoglicic acid[4] Cromoglicate; Cromoglycate; Cromolyn; Cromolyn Sodium; --[3] 2, 85, 98
35 Caffeine [1] Caffeine[1] Caffeine; [11] ADORA1,
ADORA2A,
PDE1B,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE5A 💬		[22] Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[9] 2, 6, 13, 21, 46, 78, 96, 97, 265
36 Midazolam [1] Midazolam[2] Midazolam; Midazolam injection; [16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[12] 2, 3, 6, 13, 21, 46, 70, 96, 97, 231, 272, 298
37 Carbidopa [1] Carbidopa[7] CARBIDOPA; DUODOPA; Lodosyn; PARCOPA; SINEMET; SINEMET CR; Stalevo; [1] DDC 💬[9] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Metabolic pathways, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬[9] 2, 4, 6, 13, 17, 90, 140, 164, 201
38 Pramipexole dihydrochloride [1] Pramipexole[7] Mirapex; Mirapex ER; Mirapexin; Pramipexol; PRAMIPEXOLE; PRAMIPEXOLE DIHYDROCHLORIDE; SIFROL; [3] DRD2,
DRD3,
DRD4 💬		[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[3] 2, 6, 20
39 Pimozide [1] Pimozide[1] Pimozide; [2] ADRA2A,
DRD2 💬		[9] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 2
40 Celecoxib [1] Celecoxib[2] Celebrex; Celecoxib; [1] PTGS2 💬[22] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[10] 2, 3, 34, 46, 70, 89, 107, 161, 171, 271
41 Colchicine [1] Colchicine[2] COLCHICINA; Colchicine; [9] TUBB,
TUBB1,
TUBB2A,
TUBB2B,
TUBB3,
TUBB4A,
TUBB4B,
TUBB6,
TUBB8 💬		[10] Alzheimer disease, Amyotrophic lateral sclerosis, Gap junction, Huntington disease, Parkinson disease, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Phagosome, Prion disease, Salmonella infection 💬[7] 2, 42, 46, 56, 93, 210, 266
42 Mexiletine hydrochloride [1] Mexiletine[4] Mexiletina; Mexiletine; Mexitil; Namuscla; [5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[5] 1, 2, 10, 113, 114
43 Quinidine gluconate [1] Quinidine[4] Nuedexta; Quinidina; Quinidine; Quinidine Sulfate; [5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[3] 2, 8, 13
44 Quinidine polygalacturonate [1] Quinidine[4] Nuedexta; Quinidina; Quinidine; Quinidine Sulfate; [5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[3] 2, 8, 13
45 Midazolam hydrochloride [1] Midazolam[2] Midazolam; Midazolam injection; [16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[12] 2, 3, 6, 13, 21, 46, 70, 96, 97, 231, 272, 298
46 Levetiracetam [1] Levetiracetam[2] KEPPRA; Levetiracetam; [1] SV2A 💬[1] ECM-receptor interaction 💬[5] 2, 4, 6, 13, 307
47 Ketamine hydrochloride [1] Ketamine[2] KETAMINE; NMDA; [5] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[8] 2, 4, 6, 13, 70, 113, 156, 215
48 Rabeprazole sodium [1] Rabeprazole[1] Rabeprazole; [2] ATP4A,
ATP4B 💬		[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[2] 2, 51
49 Aldesleukin [1] Aldesleukin[4] ALDESLEUKIN; ILT-101; Proleukin; Recombinant human interleukin-2; [3] IL2RA,
IL2RB,
IL2RG 💬		[14] Cytokine-cytokine receptor interaction, Endocytosis, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Inflammatory bowel disease, JAK-STAT signaling pathway, Measles, PI3K-Akt signaling pathway, Pathways in cancer, Primary immunodeficiency, Th1 and Th2 cell differentiation, Th17 cell differentiation, Transcriptional misregulation in cancer, Viral protein interaction with cytokine and cytokine receptor 💬[6] 2, 35, 49, 65, 96, 97
50 Methylprednisolone sodium succinate [1] Methylprednisolone[4] Medrol; Methylprednisolon; Methylprednisolone; Methylprednisolone acetate; [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[48] 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 86, 93, 95, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300
51 Mycophenolate mofetil [1] Mycophenolate mofetil[3] CellCept; Mycophenolate Mofetil; Mycophenolate mofetil TEVA; [2] IMPDH1,
IMPDH2 💬		[3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism 💬[34] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300
52 Sirolimus [1] Sirolimus[3] RAPAMUNE; Rapamycin; Sirolimus; [1] MTOR 💬[51] AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬[41] 2, 6, 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331
53 Thalidomide [1] Thalidomide[1] Thalidomide; [1] TNF 💬[67] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[20] 2, 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331
54 Riluzole [1] Riluzole[2] Rilutek; Riluzole; [14] GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[23] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Systemic lupus erythematosus, Transcriptional misregulation in cancer, cAMP signaling pathway 💬[9] 2, 3, 5, 8, 13, 17, 18, 203, 206
55 Botulinum toxin type A [1] Botulinum toxin type A[8] BOTOX; Botulinum toxin A; BOTULINUM TOXIN TYPE A; BTX-A; Dysport; IncobotulinumtoxinA; OnabotulinumtoxinA; Xeomin; [1] SNAP25 💬[2] Insulin secretion, Synaptic vesicle cycle 💬[13] 2, 5, 6, 7, 13, 15, 17, 36, 51, 70, 113, 149, 226
56 Ropinirole hydrochloride [1] Ropinirole[3] Requip; Ropinirole; ROPINIROLE HYDROCHLORIDE; [3] DRD2,
DRD3,
DRD4 💬		[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[4] 2, 6, 74, 309
57 Lithium carbonate [1] Lithium carbonate[2] Lithium; LITHIUM CARBONATE; --[6] 2, 13, 17, 18, 19, 127
58 Trazodone hydrochloride [1] Trazodone[1] Trazodone; [4] HTR2A,
HTR2B,
HTR2C,
SLC6A4 💬		[6] Calcium signaling pathway, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse, Synaptic vesicle cycle 💬[1] 2
59 Dextromethorphan hydrobromide [1] Dextromethorphan[4] Dextromethorphan; Dextromethorphan hydrobromide; Dextrometorfano; Nuedexta; [6] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[11] 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
60 Minocycline hydrochloride [1] Minocycline[3] Minocycline; MINOCYCLINE HYDROCHLORIDE; Minomycin; --[14] 2, 6, 8, 13, 46, 84, 85, 90, 94, 162, 201, 206, 280, 299
61 Moxifloxacin hydrochloride [1] Moxifloxacin[2] Moxifloxacin; Moxifloxacin hydrochloride; --[9] 2, 6, 46, 49, 85, 86, 113, 240, 299
62 Abacavir sulfate [1] Abacavir[4] Abacavir; Abacavir sulfate; Triumeq; Ziagen; --[4] 2, 135, 265, 325
63 Ceftriaxone sodium [1] Ceftriaxone[1] Ceftriaxone; --[3] 2, 6, 97
64 Metformin hydrochloride [1] Metformin[5] Metformin; Metformin HCl; Metformin hydrochloride; METFORMINA; Metformine; [2] PRKAA1,
PRKAA2 💬		[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬[24] 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301
65 Pioglitazone hydrochloride [1] Pioglitazone[1] Pioglitazone; [1] PPARG 💬[11] AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299
66 Testosterone cypionate [1] Testosterone[1] Testosterone; [1] AR 💬[4] Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬[9] 1, 2, 3, 13, 60, 76, 78, 113, 265
67 Testosterone enanthate [1] Testosterone[1] Testosterone; [1] AR 💬[4] Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬[9] 1, 2, 3, 13, 60, 76, 78, 113, 265
68 Testosterone propionate [1] Testosterone[1] Testosterone; [1] AR 💬[4] Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬[9] 1, 2, 3, 13, 60, 76, 78, 113, 265
69 Tamoxifen citrate [1] Tamoxifen[2] TAMOXIFEN; TAMOXIFEN CITRATE; [2] ESR1,
ESR2 💬		[10] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[4] 2, 86, 113, 227
70 Betamethasone sodium phosphate [1] Betamethasone[1] Betamethasone; [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[7] 2, 28, 46, 83, 90, 96, 235
71 Methylprednisolone acetate [1] Methylprednisolone[4] Medrol; Methylprednisolon; Methylprednisolone; METHYLPREDNISOLONE ACETATE; [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[48] 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 86, 93, 95, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300
72 Leuprolide acetate [1] Leuprolide[2] Leuprolide; Leuprorelin; [1] GNRHR 💬[2] GnRH signaling pathway, Neuroactive ligand-receptor interaction 💬[5] 1, 2, 3, 51, 76
73 Sodium lauryl sulfate [1] Sodium lauryl sulfate[0] --[1] 2
74 Ubidecarenone [1] Ubidecarenone[3] Coenzyme Q-10; Coenzyme Q10; CoQ10; --[13] 2, 5, 6, 8, 10, 18, 46, 57, 86, 113, 193, 214, 215
75 Methylatropine nitrate [1] Atropine[2] Atropina; Atropine; [5] CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬		[13] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬[2] 2, 299
76 Dexmedetomidine hydrochloride [1] Dexmedetomidine[4] Dexdor; DEXMEDETOMIDINA; DEXMEDETOMIDINE; DEXMEDETOMIDINE HYDROCHLORIDE; [3] ADRA2A,
ADRA2B,
ADRA2C 💬		[2] Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[13] 2, 4, 6, 21, 34, 46, 70, 107, 113, 212, 215, 226, 280
77 Febuxostat [1] Febuxostat[1] Febuxostat; [1] XDH 💬[5] Caffeine metabolism, Drug metabolism - other enzymes, Metabolic pathways, Peroxisome, Purine metabolism 💬[3] 2, 6, 13
78 Sulpiride [1] Sulpiride[0] [1] DRD2 💬[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[5] 2, 6, 17, 46, 70
79 Ampicillin hydrate [1] Ampicillin[1] ABPC; --[5] 2, 6, 13, 84, 299
80 Betamethasone valerate [1] Betamethasone[1] Betamethasone; [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[7] 2, 28, 46, 83, 90, 96, 235
81 Ibudilast [1] Ibudilast[1] Ibudilast; [8] CYSLTR1,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PTGIR 💬		[16] Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Parathyroid hormone synthesis, secretion and action, Platelet activation, Progesterone-mediated oocyte maturation, Purine metabolism, Regulation of lipolysis in adipocytes, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 2, 13
82 Betamethasone acetate [1] Betamethasone[1] Betamethasone; [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[7] 2, 28, 46, 83, 90, 96, 235
83 Caffeine hydrate [1] Caffeine[1] Caffeine; [11] ADORA1,
ADORA2A,
PDE1B,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE5A 💬		[22] Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[9] 2, 6, 13, 21, 46, 78, 96, 97, 265
84 Edaravone [1] Edaravone[3] Edaravone; Methylphenylpyrazolone; Norphenazone; --[2] 2, 22
85 Betamethasone dipropionate [1] Betamethasone[1] Betamethasone; [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[7] 2, 28, 46, 83, 90, 96, 235
86 Betamethasone butyrate propionate [1] Betamethasone[1] Betamethasone; [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[7] 2, 28, 46, 83, 90, 96, 235
87 Atropine sulfate [1] Atropine[2] Atropina; Atropine; [5] CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬		[13] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬[2] 2, 299
88 Ampicillin sodium [1] Ampicillin[1] ABPC; --[5] 2, 6, 13, 84, 299
89 Ciprofloxacin hydrochloride [1] Ciprofloxacin[2] CIPROFLOXACIN; CIPROFLOXACIN HYDROCHLORIDE; --[5] 2, 60, 96, 97, 299
90 Quinidine sulfate [1] Quinidine[4] Nuedexta; Quinidina; Quinidine; Quinidine Sulfate; [5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[3] 2, 8, 13
91 Betamethasone benzoate [1] Betamethasone[1] Betamethasone; [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[7] 2, 28, 46, 83, 90, 96, 235
92 Vitamin E [1] Vitamin E[2] Alpha-tocopherol; Vitamin E; --[12] 2, 6, 13, 20, 46, 49, 90, 96, 97, 206, 299, 317
93 Rasagiline mesylate [1] Rasagiline[4] Azilect; Rasagilina; Rasagiline; Rasagiline mesylate; [1] MAOB 💬[14] Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬[7] 2, 5, 6, 13, 17, 58, 66
94 Escitalopram oxalate [1] Escitalopram[3] Citalopram; Escitalopram; Escitalopram oxalate; [1] SLC6A4 💬[2] Serotonergic synapse, Synaptic vesicle cycle 💬[3] 2, 6, 13
95 Tocilizumab [1] Tocilizumab[3] Actemra; RoActemra; TOCILIZUMAB; [1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[21] 2, 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331
96 Somatropin [1] Somatotropin[17] Genotropin; Growth Hormone; Human growth hormone; Humatrope; Norditropin; Norditropin SimpleXx; NUTROPIN; Nutropin AQ; NutropinAq; OMNITROPE; Recombinant human growth hormone; RhGH; SAIZEN; Somatotropin; Somatropin; SOMATROPINA; Zomacton; [1] GHR 💬[5] Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway 💬[23] 2, 3, 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 265, 274, 276, 299
97 Talampanel [1] Talampanel[1] Talampanel; [4] GRIA1,
GRIA2,
GRIA3,
GRIA4 💬		[16] Amphetamine addiction, Amyotrophic lateral sclerosis, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Transcriptional misregulation in cancer, cAMP signaling pathway 💬[2] 2, 6
98 Rimabotulinumtoxin B [1] Botulinum toxin type B[3] Botulinum toxin type B; NEUROBLOC; RimabotulinumtoxinB; [1] SNAP25 💬[2] Insulin secretion, Synaptic vesicle cycle 💬[4] 2, 6, 13, 51
99 Albumin human [1] Albumin human[5] Albumin; Human albumin; Human serum albumin; Optison; Serum albumin; --[3] 2, 78, 96
100 Anakinra [1] Anakinra[2] ANAKINRA; Kineret; [2] IL1R1,
IL1R2 💬		[15] Amoebiasis, Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Inflammatory mediator regulation of TRP channels, MAPK signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Pathogenic Escherichia coli infection, Prostate cancer, Shigellosis, Th17 cell differentiation, Transcriptional misregulation in cancer 💬[19] 2, 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299
101 Atropine oxide hydrochloride [1] Atropine[2] Atropina; Atropine; [5] CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬		[13] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬[2] 2, 299
102 Basiliximab [1] Basiliximab[2] Basiliximab; Simulect; [1] IL2RA 💬[11] Cytokine-cytokine receptor interaction, Endocytosis, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, JAK-STAT signaling pathway, Measles, PI3K-Akt signaling pathway, Pathways in cancer, Th1 and Th2 cell differentiation, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[6] 2, 50, 66, 97, 222, 228
103 Lactose [1] Lactose[1] Lactose; --[6] 2, 6, 13, 97, 228, 310
104 Epoetin alfa [1] Erythropoietin[4] EPOETIN ALFA; Epoetin beta; Erythropoietin; Neorecormon; [1] EPOR 💬[5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬[10] 2, 6, 13, 18, 22, 46, 47, 70, 95, 96
105 Filgrastim [1] Filgrastim[7] Filgrastim; Filgrastim Hexal; G-CSF; Granulocyte Colony Stimulating Factor; NEUPOGEN; TEVAGRASTIM; ZARZIO; [1] CSF3R 💬[5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬[34] 2, 6, 11, 13, 16, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331
106 Mecobalamin [1] Mecobalamin[2] Mecobalamin; Methylcobalamin; --[2] 2, 70
107 Lenograstim [1] Lenograstim[2] G-CSF; LENOGRASTIM; [1] CSF3R 💬[5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬[7] 2, 13, 16, 18, 19, 57, 65
108 Bosutinib [1] Bosutinib[1] BOSUTINIB; [2] ABL1,
SRC 💬		[49] Adherens junction, Axon guidance, Bacterial invasion of epithelial cells, Bladder cancer, C-type lectin receptor signaling pathway, Cell cycle, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Chronic myeloid leukemia, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Fluid shear stress and atherosclerosis, Focal adhesion, GABAergic synapse, Gap junction, GnRH signaling pathway, Hepatitis B, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Inflammatory mediator regulation of TRP channels, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, MicroRNAs in cancer, Mitophagy - animal, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Oxytocin signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Platelet activation, Prolactin signaling pathway, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Thyroid hormone signaling pathway, Tight junction, Tuberculosis, VEGF signaling pathway, Viral carcinogenesis, Viral myocarditis, Yersinia infection 💬[2] 2, 67
109 Calusterone [1] Calusterone[0] [1] AR 💬[4] Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬[3] 2, 46, 71
110 Cimetidine hydrochloride [1] Cimetidine[1] Cimetidine; [1] HRH2 💬[3] Calcium signaling pathway, Gastric acid secretion, Neuroactive ligand-receptor interaction 💬[2] 2, 254
111 Creatinine [1] Creatinine[1] Creatinine; --[4] 2, 46, 60, 70
112 Darunavir [1] Darunavir[1] Darunavir; --[1] 2
113 Dextromethorphan [1] Dextromethorphan[4] Dextromethorphan; Dextromethorphan hydrobromide; Dextrometorfano; Nuedexta; [6] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[11] 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
114 Dextromethorphan polistirex [1] Dextromethorphan[4] Dextromethorphan; Dextromethorphan hydrobromide; Dextrometorfano; Nuedexta; [6] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[11] 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
115 Atropine methylbromide [1] Atropine[2] Atropina; Atropine; [5] CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬		[13] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬[2] 2, 299
116 Dutasteride [1] Dutasteride[2] Dutasterida; Dutasteride; [2] SRD5A1,
SRD5A2 💬		[3] Metabolic pathways, Prostate cancer, Steroid hormone biosynthesis 💬[2] 1, 2
117 Glatiramer acetate [1] Glatiramer[5] COP-1; COPAXONE; Copolymer-1; Glatiramer; Glatiramer acetate; [20] HLA-A,
HLA-B,
HLA-C,
HLA-DMA,
HLA-DMB,
HLA-DOA,
HLA-DOB,
HLA-DPA1,
HLA-DPB1,
HLA-DQA1,
HLA-DQA2,
HLA-DQB1,
HLA-DRA,
HLA-DRB1,
HLA-DRB3,
HLA-DRB4,
HLA-DRB5,
HLA-E,
HLA-F,
HLA-G 💬		[32] Allograft rejection, Antigen processing and presentation, Asthma, Autoimmune thyroid disease, Cell adhesion molecules, Cellular senescence, Endocytosis, Epstein-Barr virus infection, Graft-versus-host disease, Hematopoietic cell lineage, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Inflammatory bowel disease, Influenza A, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Natural killer cell mediated cytotoxicity, Phagosome, Rheumatoid arthritis, Staphylococcus aureus infection, Systemic lupus erythematosus, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Viral carcinogenesis, Viral myocarditis 💬[4] 2, 13, 96, 156
118 Guanabenz [1] Guanabenz[1] Guanabenz; [3] ADRA2A,
ADRA2B,
ADRA2C 💬		[2] Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[2] 2, 13
119 Levosimendan [1] Levosimendan[1] LEVOSIMENDAN; [2] PDE3A,
PDE3B 💬		[11] Apelin signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Progesterone-mediated oocyte maturation, Purine metabolism, Regulation of lipolysis in adipocytes, Renin secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 2
120 Lithium citrate [1] Lithium citrate[2] Lithium; LITHIUM CITRATE; --[5] 2, 5, 6, 7, 8
121 Memantine hydrochloride [1] Memantine[3] EBIXA; Memantine; MEMANTINE HYDROCHLORIDE; [5] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[7] 2, 6, 8, 13, 49, 127, 205
122 Metformin [1] Metformin[5] Metformin; Metformin HCl; Metformin hydrochloride; Metformina; Metformine; [2] PRKAA1,
PRKAA2 💬		[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬[24] 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301
123 Methylprednisolone hemisuccinate [1] Methylprednisolone[4] Medrol; Methylprednisolon; Methylprednisolone; Methylprednisolone acetate; [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[48] 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 86, 93, 95, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300
124 Methylprednisolone sodium phosphate [1] Methylprednisolone[4] Medrol; Methylprednisolon; Methylprednisolone; Methylprednisolone acetate; [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[48] 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 86, 93, 95, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300
125 Methylprednisolone suleptanate [1] Methylprednisolone[4] Medrol; Methylprednisolon; Methylprednisolone; Methylprednisolone acetate; [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[48] 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 86, 93, 95, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300
126 Midazolam maleate [1] Midazolam[2] Midazolam; Midazolam injection; [16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[12] 2, 3, 6, 13, 21, 46, 70, 96, 97, 231, 272, 298
127 Minocycline [1] Minocycline[3] Minocycline; Minocycline hydrochloride; Minomycin; --[14] 2, 6, 8, 13, 46, 84, 85, 90, 94, 162, 201, 206, 280, 299
128 Mycophenolate mofetil hydrochloride [1] Mycophenolate mofetil[3] CellCept; Mycophenolate mofetil; Mycophenolate mofetil TEVA; [2] IMPDH1,
IMPDH2 💬		[3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism 💬[34] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300
129 Mycophenolate sodium [1] Mycophenolate mofetil[3] CELLCEPT; Mycophenolate Mofetil; Mycophenolate mofetil TEVA; [2] IMPDH1,
IMPDH2 💬		[3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism 💬[34] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300
130 Mycophenolic acid [1] Mycophenolic acid[5] Acido Micofenolico; MICOFENOLICO ACIDO; Mycophenolate; Mycophenolic acid; Myfortic; [2] IMPDH1,
IMPDH2 💬		[3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism 💬[36] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300
131 Human serum albumin [1] Albumin human[5] Albumin; Human albumin; Human serum albumin; Optison; Serum albumin; --[3] 2, 78, 96
132 Enoxacin hydrate [1] Enoxacin[1] Enoxacin; --[1] 2
133 Pleconaril [1] Pleconaril[1] PLECONARIL; --[1] 2
134 Pramipexole [1] Pramipexole[7] Mirapex; Mirapex ER; Mirapexin; Pramipexol; Pramipexole; PRAMIPEXOLE DIHYDROCHLORIDE; SIFROL; [3] DRD2,
DRD3,
DRD4 💬		[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[3] 2, 6, 20
135 Ranolazine [1] Ranolazine[3] RANEXA; Ranolazina; Ranolazine; --[6] 2, 58, 86, 96, 113, 114
136 Ranolazine hydrochloride [1] Ranolazine[3] RANEXA; Ranolazina; Ranolazine; --[6] 2, 58, 86, 96, 113, 114
137 Tenofovir [1] Tenofovir[1] Tenofovir; --[6] 2, 13, 25, 93, 265, 325
138 Testosterone ketolaurate [1] Testosterone[1] Testosterone; [1] AR 💬[4] Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬[9] 1, 2, 3, 13, 60, 76, 78, 113, 265
139 Testosterone undecanoate [1] Testosterone[1] Testosterone; [1] AR 💬[4] Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬[9] 1, 2, 3, 13, 60, 76, 78, 113, 265
140 Arundic acid [1] Arundic acid[1] Arundic Acid; --[1] 2
141 Olanzapine pamoate [1] Olanzapine[2] OLANZAPINE; Zyprexa; [11] ADRA1A,
ADRA1B,
ADRA1D,
DRD2,
DRD3,
DRD4,
HRH1,
HTR2A,
HTR2B,
HTR2C,
HTR6 💬		[16] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Salivary secretion, Serotonergic synapse, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 2, 8
142 Abacavir [1] Abacavir[4] Abacavir; Abacavir sulfate; Triumeq; Ziagen; --[4] 2, 135, 265, 325
143 Esketamine [1] Esketamine[3] ESKETAMINE; KETAMINE; S-ketamine; [5] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[3] 2, 4, 70
144 Lacosamide [1] Lacosamide[1] Lacosamide; [2] SCN3A,
SCN9A 💬		[1] Taste transduction 💬[3] 2, 46, 149
145 Deferiprone [1] Deferiprone[2] DEFERIPRONE; Ferriprox; --[6] 2, 6, 18, 120, 122, 233
146 Ceftriaxone [1] Ceftriaxone[1] Ceftriaxone; --[3] 2, 6, 97
147 Citalopram [1] Escitalopram[3] Citalopram; Escitalopram; Escitalopram oxalate; [1] SLC6A4 💬[2] Serotonergic synapse, Synaptic vesicle cycle 💬[3] 2, 6, 13
148 Clenbuterol [1] Clenbuterol[1] Clenbuterol; [1] ADRB2 💬[9] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[5] 1, 2, 6, 13, 256
149 Cromoglicic acid [1] Cromoglicic acid[4] Cromoglicate; Cromoglycate; Cromolyn; Cromolyn Sodium; --[3] 2, 85, 98
150 Eperisone [1] Eperisone[1] EPERISONE; --[1] 2
151 Escitalopram [1] Escitalopram[3] Citalopram; Escitalopram; Escitalopram oxalate; [1] SLC6A4 💬[2] Serotonergic synapse, Synaptic vesicle cycle 💬[3] 2, 6, 13
152 Fasudil [1] Fasudil[1] Fasudil; [2] ROCK1,
ROCK2 💬		[23] Axon guidance, Chemokine signaling pathway, Focal adhesion, Human cytomegalovirus infection, Leukocyte transendothelial migration, Lipid and atherosclerosis, MicroRNAs in cancer, Oxytocin signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Platelet activation, Proteoglycans in cancer, Regulation of actin cytoskeleton, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, TGF-beta signaling pathway, Tight junction, Vascular smooth muscle contraction, Wnt signaling pathway, Yersinia infection, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[4] 2, 5, 7, 51
153 Ketamine [1] Ketamine[2] KETAMINE; NMDA; [5] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[8] 2, 4, 6, 13, 70, 113, 156, 215
154 Memantine [1] Memantine[3] Ebixa; MEMANTINE; MEMANTINE HYDROCHLORIDE; [5] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[7] 2, 6, 8, 13, 49, 127, 205
155 Mexiletine [1] Mexiletine[4] Mexiletina; Mexiletine; Mexitil; Namuscla; [5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[5] 1, 2, 10, 113, 114
156 Moxifloxacin [1] Moxifloxacin[2] Moxifloxacin; Moxifloxacin Hydrochloride; --[9] 2, 6, 46, 49, 85, 86, 113, 240, 299
157 Palmidrol [1] Palmidrol[1] Palmitoylethanolamide; --[1] 2
158 Pioglitazone [1] Pioglitazone[1] Pioglitazone; [1] PPARG 💬[11] AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299
159 Quinidine [1] Quinidine[4] Nuedexta; Quinidina; Quinidine; Quinidine Sulfate; [5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[3] 2, 8, 13
160 Rabeprazole [1] Rabeprazole[1] Rabeprazole; [2] ATP4A,
ATP4B 💬		[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[2] 2, 51
161 Rasagiline [1] Rasagiline[4] AZILECT; Rasagilina; Rasagiline; Rasagiline mesylate; [1] MAOB 💬[14] Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬[7] 2, 5, 6, 13, 17, 58, 66
162 Ropinirole [1] Ropinirole[3] REQUIP; ROPINIROLE; Ropinirole Hydrochloride; [3] DRD2,
DRD3,
DRD4 💬		[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[4] 2, 6, 74, 309
163 Sultopride [1] Sulpiride[0] [1] DRD2 💬[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[5] 2, 6, 17, 46, 70
164 Tacrolimus [1] Tacrolimus[2] Prograf; TACROLIMUS; [5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
165 Tamoxifen [1] Tamoxifen[2] Tamoxifen; TAMOXIFEN CITRATE; [2] ESR1,
ESR2 💬		[10] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[4] 2, 86, 113, 227
166 Trazodone [1] Trazodone[1] Trazodone; [4] HTR2A,
HTR2B,
HTR2C,
SLC6A4 💬		[6] Calcium signaling pathway, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse, Synaptic vesicle cycle 💬[1] 2
167 Trimetazidine [1] Trimetazidine[1] Trimetazidine; --[3] 2, 58, 86
168 Perampanel [1] Perampanel[2] Fycompa; Perampanel; [4] GRIA1,
GRIA2,
GRIA3,
GRIA4 💬		[16] Amphetamine addiction, Amyotrophic lateral sclerosis, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Transcriptional misregulation in cancer, cAMP signaling pathway 💬[3] 2, 6, 144
169 Ezogabine [1] Ezogabine[4] Ezogabine; Potiga; RETIGABINE; Trobalt; [5] KCNQ1,
KCNQ2,
KCNQ3,
KCNQ4,
KCNQ5 💬		[6] Adrenergic signaling in cardiomyocytes, Cholinergic synapse, Gastric acid secretion, Pancreatic secretion, Protein digestion and absorption, Vibrio cholerae infection 💬[2] 2, 144
170 Dexpramipexole [1] Dexpramipexole[1] Dexpramipexole; [5] DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 2
171 Pridopidine [1] Pridopidine[1] Pridopidine; [1] DRD2 💬[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[3] 2, 6, 8
172 Dolutegravir [1] Dolutegravir[2] Dolutegravir; Triumeq; --[2] 2, 265
173 Trametinib [1] Trametinib[2] Mekinist; Trametinib; [2] MAP2K1,
MAP2K2 💬		[89] Acute myeloid leukemia, Alcoholism, Alzheimer disease, Apelin signaling pathway, Apoptosis, Autophagy - animal, B cell receptor signaling pathway, Bladder cancer, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Choline metabolism in cancer, Cholinergic synapse, Chronic myeloid leukemia, Colorectal cancer, Cushing syndrome, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endometrial cancer, ErbB signaling pathway, Estrogen signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatitis B, Hepatitis C, Hepatocellular carcinoma, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Influenza A, Insulin signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Long-term depression, Long-term potentiation, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-small cell lung cancer, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Renal cell carcinoma, Salmonella infection, Serotonergic synapse, Signaling pathways regulating pluripotency of stem cells, Sphingolipid signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Thyroid cancer, Thyroid hormone signaling pathway, Toll-like receptor signaling pathway, VEGF signaling pathway, Vascular smooth muscle contraction, Yersinia infection, cAMP signaling pathway, cGMP-PKG signaling pathway, mTOR signaling pathway 💬[4] 2, 34, 279, 280
174 Masitinib [1] Masitinib[1] Masitinib; [1] KIT 💬[11] Acute myeloid leukemia, Breast cancer, Central carbon metabolism in cancer, Hematopoietic cell lineage, MAPK signaling pathway, Melanogenesis, PI3K-Akt signaling pathway, Pathways in cancer, Phospholipase D signaling pathway, Rap1 signaling pathway, Ras signaling pathway 💬[6] 2, 5, 6, 13, 46, 96
175 Tirasemtiv [1] Tirasemtiv[1] Tirasemtiv; --[1] 2
176 Ozanezumab [1] Ozanezumab[1] Ozanezumab; [1] RTN4 💬[1] Alzheimer disease 💬[1] 2
177 Tenofovir alafenamide [1] Tenofovir alafenamide[1] Tenofovir alafenamide; --[2] 2, 13
178 Censavudine [1] Censavudine[1] CENSAVUDINE; --[2] 2, 127
179 Rasagiline tartrate [1] Rasagiline[4] AZILECT; Rasagilina; RASAGILINE; RASAGILINE MESYLATE; [1] MAOB 💬[14] Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬[7] 2, 5, 6, 13, 17, 58, 66
180 Cannabidiol [1] Cannabidiol[3] Cannabidiol; Epidyolex; Sativex; [2] CNR1,
CNR2 💬		[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬[19] 2, 6, 8, 13, 36, 46, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271
181 Ravulizumab [1] Ravulizumab[2] Ravulizumab; Ultomiris; [1] C5 💬[10] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[7] 2, 11, 13, 50, 62, 66, 109
182 Reldesemtiv [1] Reldesemtiv[2] CK-2127107; RELDESEMTIV; [1] TNNC2 💬[1] Calcium signaling pathway 💬[2] 2, 3
183 Arimoclomol [1] Arimoclomol[1] ARIMOCLOMOL; --[3] 2, 15, 19
184 Triheptanoin [1] Triheptanoin[1] Triheptanoin; --[10] 2, 8, 65, 149, 156, 248, 256, 257, 317, 324
185 Pegcetacoplan [1] Pegcetacoplan[1] Pegcetacoplan; [1] C3 💬[17] Alcoholic liver disease, Chagas disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Leishmaniasis, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Phagosome, Shigellosis, Staphylococcus aureus infection, Systemic lupus erythematosus, Tuberculosis, Viral carcinogenesis 💬[3] 2, 62, 222
186 Verdiperstat [1] Verdiperstat[1] Verdiperstat; [1] MPO 💬[5] Acute myeloid leukemia, Drug metabolism - other enzymes, Neutrophil extracellular trap formation, Phagosome, Transcriptional misregulation in cancer 💬[3] 2, 17, 127
187 Tofersen [1] Tofersen[1] Tofersen; [1] SOD1 💬[8] Amyotrophic lateral sclerosis, Chemical carcinogenesis - reactive oxygen species, Huntington disease, Longevity regulating pathway - multiple species, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Peroxisome, Prion disease 💬[1] 2
188 Taurursodiol [1] Tauroursodeoxycholic acid[2] Tauroursodeoxycholic acid; TUDCA; --[4] 2, 13, 93, 299