Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank 薬物名（臨床試験情報から抽出） KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Ambrisentan 💬1件: Ambrisentan1件: Ambrisentan1件: EDNRA 💬 7件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬8件: 51, 66, 84, 85, 86, 88, 210, 211 💬
2 Ascorbic acid 💬1件: Ascorbic acid2件: Ascorbic acid; Vitamin C--8件: 10, 97, 192, 206, 210, 211, 212, 298 💬
3 Aspirin 💬1件: Acetylsalicylic acid2件: Acetylsalicylic acid; Aspirin2件: PTGS1,
PTGS2 💬 		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬12件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 210, 231, 271 💬
4 Bosentan 💬1件: Bosentan2件: Bosentan; Bosentan monohydrate2件: EDNRA,
EDNRB 💬 		9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬11件: 40, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
5 Bosentan 💬1件: Bosentan2件: Bosentan; Bosentan monohydrate2件: EDNRA,
EDNRB 💬 		9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬11件: 40, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
6 Carvedilol 💬1件: Carvedilol1件: Carvedilol5件: ADRA1A,
ADRA1B,
ADRA1D,
ADRB1,
ADRB2 💬 		15件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬6件: 6, 46, 57, 86, 113, 210 💬
7 Carvedilol phosphate 💬1件: Carvedilol1件: Carvedilol5件: ADRA1A,
ADRA1B,
ADRA1D,
ADRB1,
ADRB2 💬 		15件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬6件: 6, 46, 57, 86, 113, 210 💬
8 Colchicine 💬1件: Colchicine1件: Colchicine9件: TUBB,
TUBB,
TUBB,
TUBB,
TUBB,
TUBB,
TUBB,
TUBB,
TUBB 💬 		11件: Alzheimer disease, Amyotrophic lateral sclerosis, Gap junction, Huntington disease, Motor proteins, Parkinson disease, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Phagosome, Prion disease, Salmonella infection 💬8件: 42, 46, 50, 56, 93, 97, 210, 266 💬
9 Dapagliflozin 💬1件: Dapagliflozin1件: Dapagliflozin--10件: 6, 28, 49, 66, 67, 86, 88, 215, 218, 222 💬
10 Digoxin 💬1件: Digoxin1件: Digoxin4件: ATP1A,
ATP1A,
ATP1A,
ATP1A 💬 		19件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Aldosterone-regulated sodium reabsorption, Bile secretion, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cytoskeleton in muscle cells, Endocrine and other factor-regulated calcium reabsorption, Gastric acid secretion, Insulin secretion, Mineral absorption, Pancreatic secretion, Protein digestion and absorption, Proximal tubule bicarbonate reclamation, Salivary secretion, Thyroid hormone signaling pathway, Thyroid hormone synthesis, cAMP signaling pathway, cGMP-PKG signaling pathway 💬3件: 8, 46, 210 💬
11 Enalapril 💬1件: Enalapril2件: Enalapril; Enalapril maleate1件: ACE 💬 6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬7件: 13, 46, 66, 113, 210, 222, 279 💬
12 Enalapril maleate 💬1件: Enalapril2件: Enalapril; Enalapril maleate1件: ACE 💬 6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬7件: 13, 46, 66, 113, 210, 222, 279 💬
13 Eplerenone 💬1件: Eplerenone1件: Eplerenone1件: NR3C2 💬 1件: Aldosterone-regulated sodium reabsorption 💬4件: 75, 113, 210, 215 💬
14 Liothyronine 💬1件: Liothyronine2件: Liothyronine; Liothyronine sodium2件: THRA,
THRB 💬 		3件: Hormone signaling, Neuroactive ligand-receptor interaction, Thyroid hormone signaling pathway 💬1件: 13 💬
15 Liothyronine I 131 💬1件: Liothyronine I-1311件: Liothyronine I 131--2件: 210, 212 💬
16 Liothyronine sodium 💬1件: Liothyronine2件: Liothyronine; Liothyronine sodium2件: THRA,
THRB 💬 		3件: Hormone signaling, Neuroactive ligand-receptor interaction, Thyroid hormone signaling pathway 💬1件: 13 💬
17 Macitentan 💬1件: Macitentan1件: Macitentan2件: EDNRA,
EDNRB 💬 		9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬5件: 51, 85, 86, 88, 210 💬
18 Nitric oxide 💬1件: Nitric Oxide1件: Nitric oxide--8件: 51, 85, 86, 88, 97, 210, 294, 299 💬
19 Pravastatin 💬1件: Pravastatin2件: Pravastatin; Pravastatin sodium1件: HMGCR 💬 3件: AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬10件: 13, 46, 49, 67, 79, 96, 164, 210, 265, 333 💬
20 Pravastatin sodium 💬1件: Pravastatin2件: Pravastatin; Pravastatin sodium1件: HMGCR 💬 3件: AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬10件: 13, 46, 49, 67, 79, 96, 164, 210, 265, 333 💬
21 Rivaroxaban 💬1件: Rivaroxaban1件: Rivaroxaban1件: F10 💬 1件: Complement and coagulation cascades 💬5件: 46, 49, 91, 210, 271 💬
22 Sacubitril 💬1件: Sacubitril1件: Sacubitril1件: MME 💬 4件: Alzheimer disease, Hematopoietic cell lineage, Protein digestion and absorption, Renin-angiotensin system 💬2件: 210, 222 💬
23 Sildenafil 💬1件: Sildenafil3件: Sildenafil; Sildenafil citrate; Sildenafilo1件: PDE5 💬 2件: Purine metabolism, cGMP-PKG signaling pathway 💬14件: 6, 46, 51, 85, 86, 113, 210, 211, 212, 225, 226, 278, 294, 299 💬
24 Sildenafil citrate 💬1件: Sildenafil3件: Sildenafil; Sildenafil citrate; Sildenafilo1件: PDE5 💬 2件: Purine metabolism, cGMP-PKG signaling pathway 💬14件: 6, 46, 51, 85, 86, 113, 210, 211, 212, 225, 226, 278, 294, 299 💬
25 Spironolactone 💬1件: Spironolactone1件: Spironolactone1件: NR3C2 💬 1件: Aldosterone-regulated sodium reabsorption 💬7件: 46, 58, 67, 86, 113, 210, 225 💬
26 Tadalafil 💬1件: Tadalafil2件: Tadalafil; Tadalafilo1件: PDE5 💬 2件: Purine metabolism, cGMP-PKG signaling pathway 💬7件: 6, 51, 75, 77, 84, 86, 113 💬
27 Treprostinil 💬1件: Treprostinil3件: Treprostinil; Treprostinil diolamine; Treprostinil sodium1件: PTGIR 💬 3件: Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬5件: 51, 85, 86, 88, 210 💬
28 Treprostinil diolamine 💬1件: Treprostinil3件: Treprostinil; Treprostinil diolamine; Treprostinil sodium1件: PTGIR 💬 3件: Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬5件: 51, 85, 86, 88, 210 💬
29 Treprostinil monosodium salt 💬1件: Treprostinil3件: Treprostinil; Treprostinil diolamine; Treprostinil sodium1件: PTGIR 💬 3件: Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬5件: 51, 85, 86, 88, 210 💬
30 Udenafil 💬1件: Udenafil1件: Udenafil1件: PDE5 💬 2件: Purine metabolism, cGMP-PKG signaling pathway 💬2件: 86, 210 💬
31 Valsartan 💬1件: Valsartan1件: Valsartan1件: AGTR1 💬 17件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Hormone signaling, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬7件: 57, 58, 66, 75, 210, 222, 224 💬
32 Vasopressin 💬1件: Vasopressin1件: Vasopressin3件: AVPR1A,
AVPR1B,
AVPR2 💬 		6件: Calcium signaling pathway, Hormone signaling, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vascular smooth muscle contraction, Vasopressin-regulated water reabsorption 💬2件: 210, 225 💬