Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. 薬物名（臨床試験情報から抽出） DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
10 MG prednisone----1件: 44 💬
25 MG prednisone----1件: 44 💬
3AB-101----4件: 35, 44, 46, 49 💬
4Abatacept1件: Abatacept1件: Abatacept 💬 2件: CD80,
CD86 💬 		13件: Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules, Graft-versus-host disease, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Rheumatoid arthritis, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis, Virion - Adenovirus 💬26件: 2, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
5Active comparator----5件: 6, 43, 44, 46, 96 💬
6Alemtuzumab1件: Alemtuzumab1件: Alemtuzumab 💬 --18件: 13, 15, 19, 20, 36, 43, 44, 46, 51, 60, 65, 85, 96, 107, 283, 284, 285, 326 💬
7ANTI-interleukin 5 (IL-5) humanized monoclonal----2件: 44, 45 💬
8Avacopan1件: Avacopan1件: Avacopan 💬 1件: C5AR1 💬 6件: Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Staphylococcus aureus infection 💬4件: 43, 44, 66, 222 💬
9Azathioprin-ratiopharm® 25 MG filmtabletten----1件: 44 💬
10Azathioprine1件: Azathioprine2件: Azathioprine ,
Azathioprine sodium 💬 		--22件: 6, 11, 13, 19, 35, 42, 43, 44, 45, 46, 49, 55, 63, 65, 66, 84, 85, 94, 95, 96, 97, 162 💬
11Azathioprine 25 MG1件: Azathioprine2件: Azathioprine ,
Azathioprine sodium 💬 		--1件: 44 💬
12AZD7986----2件: 44, 299 💬
13Belimumab1件: Belimumab1件: Belimumab 💬 1件: TNFSF13B 💬 4件: Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬13件: 11, 13, 43, 44, 46, 49, 51, 53, 63, 66, 95, 222, 296 💬
14Benralizumab1件: Benralizumab1件: Benralizumab 💬 1件: IL5RA 💬 4件: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, Pathways in cancer 💬5件: 44, 45, 98, 162, 299 💬
15Blisibimod1件: Blisibimod1件: Blisibimod 💬 --5件: 43, 44, 49, 63, 66 💬
16CCX168----6件: 43, 44, 49, 66, 109, 222 💬
17Chimeric monoclonal antibody, IGG4 subtype----2件: 43, 44 💬
18Corticosteroid and azathioprine----4件: 42, 43, 44, 45 💬
19Cyclophosphamide1件: Cyclophosphamide2件: Cyclophosphamide ,
Cyclophosphamide 💬 		--44件: 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 93, 96, 162, 164, 172, 205, 221, 222, 224, 265, 274, 283, 284, 285, 288, 326, 331 💬
20Cyclophosphamide followed BY methotrexate (azathioprine) + glucocorticoids or methotrexate (azathioprine) + glucocorticoids1件: Cyclophosphamide2件: Cyclophosphamide ,
Cyclophosphamide 💬 		--1件: 44 💬
21Cyclophosphamide/azathioprine1件: Cyclophosphamide2件: Cyclophosphamide ,
Cyclophosphamide 💬 		--1件: 44 💬
22Cyclophosphamidum 500 MG1件: Cyclophosphamide2件: Cyclophosphamide ,
Cyclophosphamide 💬 		--1件: 44 💬
23Depemokimab1件: Depemokimab1件: Depemokimab 💬 1件: IL5 💬 13件: Allograft rejection, Asthma, Autoimmune thyroid disease, Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, Hematopoietic cell lineage, IL-17 signaling pathway, Inflammatory bowel disease, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Pathways in cancer, T cell receptor signaling pathway, Th1 and Th2 cell differentiation 💬2件: 44, 45 💬
24Endoxan® 500 MG----1件: 44 💬
25Fasenra1件: Benralizumab1件: Benralizumab 💬 1件: IL5RA 💬 4件: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, Pathways in cancer 💬5件: 44, 45, 98, 162, 299 💬
26Fludarabine1件: Fludarabine2件: Fludarabine phosphate ,
Fludarabine 💬 		1件: RRM1 💬 4件: Drug metabolism - other enzymes, Glutathione metabolism, Purine metabolism, Pyrimidine metabolism 💬23件: 11, 13, 19, 34, 35, 36, 44, 46, 49, 51, 60, 61, 62, 65, 85, 96, 107, 164, 222, 283, 284, 285, 326 💬
27Galen® tablet----2件: 43, 44 💬
28Glucocorticoids----10件: 35, 40, 41, 43, 44, 75, 96, 221, 222, 300 💬
29Glucocorticoids - reduced dose----2件: 43, 44 💬
30Glucocorticoids - standard dose----2件: 43, 44 💬
31GSK3511294----2件: 44, 45 💬
32Gusperimus1件: Gusperimus2件: Gusperimus trihydrochloride ,
Gusperimus 💬 		--1件: 44 💬
33Gusperimus + glucocorticoids1件: Gusperimus2件: Gusperimus trihydrochloride ,
Gusperimus 💬 		--1件: 44 💬
34Hydroxychloroquine1件: Hydroxychloroquine2件: Hydroxychloroquine sulfate ,
Hydroxychloroquine 💬 		--26件: 6, 13, 34, 41, 43, 44, 45, 46, 48, 49, 53, 56, 63, 66, 84, 96, 97, 107, 218, 222, 224, 234, 254, 271, 298, 299 💬
35Idefirix1件: Imlifidase1件: Imlifidase 💬 --3件: 43, 44, 113 💬
36IFX-11件: Vilobelimab1件: Vilobelimab 💬 1件: C5 💬 11件: Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Regulation of actin cytoskeleton, Staphylococcus aureus infection, Systemic lupus erythematosus 💬3件: 43, 44, 269 💬
37Imlifidase1件: Imlifidase1件: Imlifidase 💬 --4件: 43, 44, 113, 221 💬
38Immunoglobulin G cleaving cystein protease derived from E. coli----2件: 43, 44 💬
39Imurel----7件: 13, 44, 45, 46, 54, 96, 97 💬
40Imurel 25 MG----3件: 44, 45, 96 💬
41INS1007----2件: 44, 299 💬
42L04ac06----2件: 44, 45 💬
43Laboratory experiments before and after mepolizumab treatment----2件: 44, 45 💬
44Mabthera1件: Rituximab1件: Rituximab 💬 1件: MS4A1 💬 1件: Hematopoietic cell lineage 💬17件: 11, 13, 35, 43, 44, 45, 46, 50, 51, 52, 61, 63, 64, 65, 83, 162, 222 💬
45MEDI-563----5件: 44, 45, 98, 162, 299 💬
46Meperizumab injection----1件: 44 💬
47Mepolizumab1件: Mepolizumab1件: Mepolizumab 💬 1件: IL5 💬 13件: Allograft rejection, Asthma, Autoimmune thyroid disease, Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, Hematopoietic cell lineage, IL-17 signaling pathway, Inflammatory bowel disease, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Pathways in cancer, T cell receptor signaling pathway, Th1 and Th2 cell differentiation 💬4件: 44, 45, 98, 162 💬
48Mesna----11件: 11, 13, 44, 45, 49, 51, 60, 65, 85, 96, 164 💬
49Metex 2,5 MG tabletten----1件: 44 💬
50Methotrexate1件: Methotrexate2件: Methotrexate ,
Methotrexate sodium 💬 		2件: DHFR,
DHFR 💬 		3件: Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬37件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 54, 55, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 284, 285, 286, 326, 331 💬
51Methotrexate 2.5 MG1件: Methotrexate2件: Methotrexate ,
Methotrexate sodium 💬 		2件: DHFR,
DHFR 💬 		3件: Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬1件: 44 💬
52Methotrexate 25 MG1件: Methotrexate2件: Methotrexate ,
Methotrexate sodium 💬 		2件: DHFR,
DHFR 💬 		3件: Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬1件: 44 💬
53Metoject 10 MG/ML, solution injectable EN seringue PRé-remplie1件: Methotrexate2件: Methotrexate ,
Methotrexate sodium 💬 		2件: DHFR,
DHFR 💬 		3件: Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬1件: 44 💬
54Mycophenolate mofetil2件: Mycophenolate mofetil,
Mycophenolic acid		4件: Mycophenolate mofetil ,
Mycophenolate mofetil hydrochloride ,
Mycophenolate sodium ,
Mycophenolic acid 💬 		2件: IMPDH,
IMPDH 💬 		2件: Drug metabolism - other enzymes, Purine metabolism 💬32件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 46, 49, 51, 53, 60, 62, 63, 65, 66, 93, 95, 96, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
55Mycophénolate MOFéTIL----1件: 44 💬
56Naltrexone hydrochloride1件: Naltrexone2件: Naltrexone hydrochloride ,
Naltrexone 💬 		3件: OPRD1,
OPRK1,
OPRM1 💬 		7件: Estrogen signaling pathway, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬9件: 10, 40, 41, 42, 43, 44, 45, 96, 97 💬
57NO plasma exchange----2件: 43, 44 💬
58NS-229----2件: 44, 45 💬
59Nucala1件: Mepolizumab1件: Mepolizumab 💬 1件: IL5 💬 13件: Allograft rejection, Asthma, Autoimmune thyroid disease, Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, Hematopoietic cell lineage, IL-17 signaling pathway, Inflammatory bowel disease, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Pathways in cancer, T cell receptor signaling pathway, Th1 and Th2 cell differentiation 💬2件: 44, 45 💬
60Nucala 100 MG powder FOR solution FOR injection1件: Mepolizumab1件: Mepolizumab 💬 1件: IL5 💬 13件: Allograft rejection, Asthma, Autoimmune thyroid disease, Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, Hematopoietic cell lineage, IL-17 signaling pathway, Inflammatory bowel disease, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Pathways in cancer, T cell receptor signaling pathway, Th1 and Th2 cell differentiation 💬2件: 44, 45 💬
61Obinutuzumab1件: Obinutuzumab1件: Obinutuzumab 💬 1件: MS4A1 💬 1件: Hematopoietic cell lineage 💬5件: 43, 44, 49, 63, 222 💬
62Orencia1件: Abatacept1件: Abatacept 💬 2件: CD80,
CD86 💬 		13件: Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules, Graft-versus-host disease, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Rheumatoid arthritis, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis, Virion - Adenovirus 💬15件: 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 160, 222, 271, 300 💬
63Pednisone----2件: 43, 44 💬
64Plaquenil - hydroxychloroquine 200MG film coated tablets1件: Hydroxychloroquine2件: Hydroxychloroquine sulfate ,
Hydroxychloroquine 💬 		--3件: 43, 44, 45 💬
65Plasma exchange----7件: 13, 43, 44, 64, 95, 171, 222 💬
66Prednisolone1件: Prednisolone1件: Prednisolone 💬 1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬38件: 3, 11, 13, 14, 18, 25, 26, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 54, 56, 60, 63, 64, 66, 81, 84, 85, 96, 97, 113, 145, 162, 222, 251, 269, 271, 296, 299, 300 💬
67Prednison acis® 20 MG----2件: 43, 44 💬
68Prednison acis® 5 MG----2件: 43, 44 💬
69Prednison acis¿ 20 MG----2件: 43, 44 💬
70Prednison acis¿ 5 MG----2件: 43, 44 💬
71Prednisone1件: Prednisone1件: Prednisone 💬 1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬54件: 2, 11, 13, 14, 18, 19, 26, 28, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 60, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 90, 93, 95, 96, 97, 113, 145, 162, 164, 205, 222, 224, 228, 251, 269, 283, 285, 288, 299, 300, 303, 307, 331 💬
72Prednisone tablets, USP1件: Prednisone1件: Prednisone 💬 1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬3件: 41, 43, 44 💬
73Procalcitonin-variants elisa-assay1件: Procalcitonin---2件: 43, 44 💬
74Rapcabtagene autoleucel----3件: 43, 44, 51 💬
75Recombinant humanized monoclonal antibody specific FOR human IL-5----1件: 44 💬
76Reslizumab1件: Reslizumab1件: Reslizumab 💬 1件: IL5 💬 13件: Allograft rejection, Asthma, Autoimmune thyroid disease, Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, Hematopoietic cell lineage, IL-17 signaling pathway, Inflammatory bowel disease, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Pathways in cancer, T cell receptor signaling pathway, Th1 and Th2 cell differentiation 💬2件: 44, 98 💬
77Rituximab1件: Rituximab1件: Rituximab 💬 1件: MS4A1 💬 1件: Hematopoietic cell lineage 💬52件: 11, 13, 14, 19, 26, 34, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 172, 220, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬
78RO0452294/V01----2件: 43, 44 💬
79RO0452294/V02----3件: 35, 43, 44 💬
80Roactemra1件: Tocilizumab1件: Tocilizumab 💬 1件: IL6R 💬 11件: Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬7件: 41, 44, 46, 51, 86, 107, 271 💬
81SB-240563----3件: 44, 45, 98 💬
82SHR-1703----1件: 44 💬
83Tezepelumab1件: Tezepelumab1件: Tezepelumab 💬 1件: TSLP 💬 2件: Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway 💬3件: 44, 45, 98 💬
84Tocilizumab1件: Tocilizumab1件: Tocilizumab 💬 1件: IL6R 💬 11件: Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬24件: 2, 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 149, 153, 266, 271, 298, 331 💬
85Tofacitinib1件: Tofacitinib2件: Tofacitinib citrate ,
Tofacitinib 💬 		4件: JAK1,
JAK2,
JAK3,
TYK2 💬 		39件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, Efferocytosis, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Hormone signaling, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬19件: 35, 38, 39, 40, 44, 46, 49, 50, 51, 53, 65, 66, 96, 97, 107, 110, 162, 271, 300 💬
86Trimethoprim sulfamethoxazole1件: Trimethoprim3件: Trimethoprim ,
Trimethoprim sulfate ,
Trimethoprim hydrochloride 💬 		--1件: 44 💬
87Vilobelimab1件: Vilobelimab1件: Vilobelimab 💬 1件: C5 💬 11件: Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Regulation of actin cytoskeleton, Staphylococcus aureus infection, Systemic lupus erythematosus 💬3件: 43, 44, 269 💬
88Vitamin D1件: Vitamin D---20件: 6, 13, 19, 41, 43, 44, 46, 49, 50, 68, 93, 95, 96, 97, 179, 222, 228, 235, 274, 299 💬
89Yellow fever vaccine1件: Yellow fever vaccine1件: Yellow fever vaccine 💬 --8件: 40, 44, 46, 50, 51, 52, 53, 107 💬