Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank 薬物名（臨床試験情報から抽出） KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Abatacept 💬1件: Abatacept1件: ABATACEPT2件: CD80,
CD86 💬 		14件: Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecule (CAM) interaction, Graft-versus-host disease, IgSF CAM signaling, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Rheumatoid arthritis, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis, Virion - Adenovirus 💬28件: 2, 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 223, 271, 284, 285, 300 💬
2 Alemtuzumab 💬1件: Alemtuzumab1件: Alemtuzumab--21件: 13, 14, 15, 19, 20, 36, 43, 44, 46, 51, 60, 63, 65, 85, 96, 107, 164, 283, 284, 285, 326 💬
3 Avacopan 💬1件: Avacopan1件: AVACOPAN1件: C5AR1 💬 6件: Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Staphylococcus aureus infection 💬4件: 43, 44, 66, 223 💬
4 Azathioprine 💬1件: Azathioprine2件: Azathioprine; AZATIOPRINA--26件: 6, 11, 13, 19, 35, 42, 43, 44, 45, 46, 49, 55, 57, 63, 65, 66, 84, 85, 93, 94, 95, 96, 97, 162, 223, 300 💬
5 Azathioprine sodium 💬1件: Azathioprine2件: AZATHIOPRINE; Azatioprina--26件: 6, 11, 13, 19, 35, 42, 43, 44, 45, 46, 49, 55, 57, 63, 65, 66, 84, 85, 93, 94, 95, 96, 97, 162, 223, 300 💬
6 Belimumab 💬1件: Belimumab1件: Belimumab1件: TNFSF13B 💬 4件: Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬17件: 11, 13, 43, 44, 46, 48, 49, 50, 51, 53, 63, 66, 95, 222, 223, 296, 300 💬
7 Benralizumab 💬1件: Benralizumab1件: Benralizumab1件: IL5RA 💬 4件: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, Pathways in cancer 💬5件: 44, 45, 98, 162, 299 💬
8 Blisibimod 💬1件: Blisibimod1件: Blisibimod--5件: 43, 44, 49, 63, 66 💬
9 Blood, whole 💬1件: Whole Blood1件: Whole Blood--9件: 44, 45, 50, 65, 86, 177, 226, 283, 299 💬
10 Cyclophosphamide 💬1件: Cyclophosphamide5件: Ciclofosfamida; CICLOFOSFAMIDE; Cyclophosphamid; Cyclophosphamide; Cyclophosphamide monohydrate--50件: 11, 13, 14, 16, 19, 20, 26, 28, 34, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 56, 60, 61, 62, 63, 65, 66, 84, 93, 96, 162, 164, 172, 205, 221, 222, 223, 224, 256, 265, 274, 283, 284, 285, 288, 326, 331 💬
11 Cyclophosphamide 💬1件: Cyclophosphamide5件: Ciclofosfamida; CICLOFOSFAMIDE; Cyclophosphamid; Cyclophosphamide; CYCLOPHOSPHAMIDE MONOHYDRATE--50件: 11, 13, 14, 16, 19, 20, 26, 28, 34, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 56, 60, 61, 62, 63, 65, 66, 84, 93, 96, 162, 164, 172, 205, 221, 222, 223, 224, 256, 265, 274, 283, 284, 285, 288, 326, 331 💬
12 Depemokimab 💬1件: Depemokimab1件: Depemokimab1件: IL5 💬 13件: Allograft rejection, Asthma, Autoimmune thyroid disease, Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, Hematopoietic cell lineage, IL-17 signaling pathway, Inflammatory bowel disease, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Pathways in cancer, T cell receptor signaling pathway, Th1 and Th2 cell differentiation 💬2件: 44, 45 💬
13 Fludarabine 💬1件: Fludarabine3件: FLUDARABINA; Fludarabine; FLUDARABINE PHOSPHATE1件: RRM1 💬 4件: Drug metabolism - other enzymes, Glutathione metabolism, Purine metabolism, Pyrimidine metabolism 💬30件: 11, 13, 14, 16, 19, 28, 34, 35, 36, 44, 46, 49, 50, 51, 60, 61, 62, 63, 65, 85, 96, 107, 164, 222, 223, 283, 284, 285, 286, 326 💬
14 Fludarabine phosphate 💬1件: Fludarabine3件: FLUDARABINA; FLUDARABINE; Fludarabine Phosphate1件: RRM1 💬 4件: Drug metabolism - other enzymes, Glutathione metabolism, Purine metabolism, Pyrimidine metabolism 💬30件: 11, 13, 14, 16, 19, 28, 34, 35, 36, 44, 46, 49, 50, 51, 60, 61, 62, 63, 65, 85, 96, 107, 164, 222, 223, 283, 284, 285, 286, 326 💬
15 Gusperimus 💬1件: Gusperimus1件: Gusperimus--1件: 44 💬
16 Gusperimus trihydrochloride 💬1件: Gusperimus1件: Gusperimus--1件: 44 💬
17 Hydroxychloroquine 💬1件: Hydroxychloroquine2件: Hydroxychloroquine; Hydroxychloroquine Sulfate--29件: 6, 13, 34, 41, 43, 44, 45, 46, 48, 49, 53, 56, 63, 66, 84, 89, 90, 96, 97, 107, 218, 222, 223, 224, 234, 254, 271, 298, 299 💬
18 Hydroxychloroquine sulfate 💬1件: Hydroxychloroquine2件: HYDROXYCHLOROQUINE; Hydroxychloroquine Sulfate--29件: 6, 13, 34, 41, 43, 44, 45, 46, 48, 49, 53, 56, 63, 66, 84, 89, 90, 96, 97, 107, 218, 222, 223, 224, 234, 254, 271, 298, 299 💬
19 Imlifidase 💬1件: Imlifidase2件: HMed-IdeS; Imlifidase--4件: 43, 44, 113, 221 💬
20 Mepolizumab 💬1件: Mepolizumab1件: MEPOLIZUMAB1件: IL5 💬 13件: Allograft rejection, Asthma, Autoimmune thyroid disease, Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, Hematopoietic cell lineage, IL-17 signaling pathway, Inflammatory bowel disease, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Pathways in cancer, T cell receptor signaling pathway, Th1 and Th2 cell differentiation 💬4件: 44, 45, 98, 162 💬
21 Mesna 💬1件: Coenzyme M1件: MESNA--12件: 11, 13, 16, 44, 45, 49, 51, 60, 65, 85, 96, 164 💬
22 Methotrexate 💬1件: Methotrexate5件: Methotrexat; METHOTREXATE; METHOTREXATE SODIUM; Methylaminopterin; METOTREXATO2件: DHFR,
DHFR2 💬 		3件: Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬41件: 11, 13, 14, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 54, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 223, 240, 256, 270, 271, 284, 285, 286, 326, 331 💬
23 Methotrexate sodium 💬1件: Methotrexate5件: Methotrexat; METHOTREXATE; METHOTREXATE SODIUM; Methylaminopterin; METOTREXATO2件: DHFR,
DHFR2 💬 		3件: Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬41件: 11, 13, 14, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 54, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 223, 240, 256, 270, 271, 284, 285, 286, 326, 331 💬
24 Methylprednisolone 💬1件: Methylprednisolone3件: Methylprednisolon; Methylprednisolone; METHYLPREDNISOLONE ACETATE1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬51件: 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 111, 127, 145, 162, 164, 211, 222, 223, 224, 271, 283, 284, 285, 296, 300 💬
25 Methylprednisolone acetate 💬1件: Methylprednisolone3件: Methylprednisolon; Methylprednisolone; Methylprednisolone acetate1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬51件: 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 111, 127, 145, 162, 164, 211, 222, 223, 224, 271, 283, 284, 285, 296, 300 💬
26 Mycophenolate mofetil 💬1件: Mycophenolate mofetil1件: Mycophenolate Mofetil2件: IMPDH1,
IMPDH2 💬 		2件: Drug metabolism - other enzymes, Purine metabolism 💬38件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 46, 49, 51, 53, 57, 60, 61, 62, 63, 65, 66, 93, 95, 96, 118, 162, 164, 222, 223, 224, 226, 234, 283, 284, 285, 300 💬
27 Mycophenolate mofetil hydrochloride 💬1件: Mycophenolate mofetil1件: Mycophenolate mofetil2件: IMPDH1,
IMPDH2 💬 		2件: Drug metabolism - other enzymes, Purine metabolism 💬38件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 46, 49, 51, 53, 57, 60, 61, 62, 63, 65, 66, 93, 95, 96, 118, 162, 164, 222, 223, 224, 226, 234, 283, 284, 285, 300 💬
28 Naltrexone 💬1件: Naltrexone2件: Naltrexone; Naltrexone Hydrochloride3件: OPRD1,
OPRK1,
OPRM1 💬 		7件: Estrogen signaling pathway, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬14件: 6, 10, 13, 40, 41, 42, 43, 44, 45, 46, 49, 96, 97, 226 💬
29 Naltrexone hydrochloride 💬1件: Naltrexone2件: Naltrexone; Naltrexone Hydrochloride3件: OPRD1,
OPRK1,
OPRM1 💬 		7件: Estrogen signaling pathway, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬14件: 6, 10, 13, 40, 41, 42, 43, 44, 45, 46, 49, 96, 97, 226 💬
30 Obinutuzumab 💬1件: Obinutuzumab1件: Obinutuzumab1件: MS4A1 💬 1件: Hematopoietic cell lineage 💬6件: 43, 44, 49, 63, 222, 223 💬
31 Prednisolone 💬1件: Prednisolone3件: Prednisolona; Prednisolone; Prednisolonum1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬48件: 3, 11, 13, 14, 18, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 54, 56, 57, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 111, 113, 145, 162, 222, 223, 251, 269, 271, 296, 299, 300 💬
32 Prednisone 💬1件: Prednisone2件: PREDNISONA; PREDNISONE1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬58件: 2, 11, 13, 14, 18, 19, 26, 28, 35, 40, 41, 42, 43, 44, 45, 46, 48, 49, 50, 51, 53, 60, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 90, 93, 95, 96, 97, 113, 127, 145, 162, 164, 205, 222, 223, 224, 228, 251, 269, 283, 284, 285, 288, 299, 300, 303, 307, 331 💬
33 Reslizumab 💬1件: Reslizumab1件: Reslizumab1件: IL5 💬 13件: Allograft rejection, Asthma, Autoimmune thyroid disease, Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, Hematopoietic cell lineage, IL-17 signaling pathway, Inflammatory bowel disease, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Pathways in cancer, T cell receptor signaling pathway, Th1 and Th2 cell differentiation 💬2件: 44, 98 💬
34 Rituximab 💬1件: Rituximab1件: Rituximab1件: MS4A1 💬 1件: Hematopoietic cell lineage 💬54件: 11, 13, 14, 19, 26, 34, 35, 36, 40, 41, 42, 43, 44, 45, 46, 48, 49, 50, 51, 52, 53, 55, 56, 60, 61, 62, 63, 64, 65, 66, 83, 84, 85, 86, 88, 93, 94, 96, 97, 162, 172, 222, 223, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬
35 Sulfamethoxazole 💬1件: Sulfamethoxazole2件: Sulfamethoxazole; Sulphamethoxazole--8件: 35, 44, 49, 61, 85, 223, 296, 299 💬
36 Tezepelumab 💬1件: Tezepelumab2件: AMG 157; Tezepelumab1件: TSLP 💬 2件: Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway 💬3件: 44, 45, 98 💬
37 Tocilizumab 💬1件: Tocilizumab2件: BAT1806; Tocilizumab1件: IL6R 💬 11件: Coronavirus disease, Cytokine-cytokine receptor interaction, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬26件: 2, 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 65, 86, 107, 149, 153, 223, 266, 271, 298, 331 💬
38 Tofacitinib 💬1件: Tofacitinib2件: Tofacitinib; TOFACITINIB CITRATE4件: JAK1,
JAK2,
JAK3,
TYK2 💬 		39件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease, Efferocytosis, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Hormone signaling, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬23件: 2, 11, 35, 38, 39, 40, 44, 46, 49, 50, 51, 53, 56, 65, 66, 84, 96, 97, 107, 110, 162, 271, 300 💬
39 Tofacitinib citrate 💬1件: Tofacitinib2件: Tofacitinib; TOFACITINIB CITRATE4件: JAK1,
JAK2,
JAK3,
TYK2 💬 		39件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease, Efferocytosis, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Hormone signaling, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬23件: 2, 11, 35, 38, 39, 40, 44, 46, 49, 50, 51, 53, 56, 65, 66, 84, 96, 97, 107, 110, 162, 271, 300 💬
40 Trimethoprim 💬1件: Trimethoprim2件: Trimethoprim; TRIMETHOPRIM SULFATE--7件: 36, 44, 49, 60, 61, 85, 299 💬
41 Trimethoprim hydrochloride 💬1件: Trimethoprim2件: TRIMETHOPRIM; TRIMETHOPRIM SULFATE--7件: 36, 44, 49, 60, 61, 85, 299 💬
42 Trimethoprim sulfate 💬1件: Trimethoprim2件: Trimethoprim; TRIMETHOPRIM SULFATE--7件: 36, 44, 49, 60, 61, 85, 299 💬
43 Vilobelimab 💬1件: Vilobelimab2件: IFX-1; Vilobelimab1件: C5 💬 11件: Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Regulation of actin cytoskeleton, Staphylococcus aureus infection, Systemic lupus erythematosus 💬3件: 43, 44, 269 💬
44 Yellow fever vaccine 💬1件: Yellow fever vaccine1件: Yellow fever vaccine--8件: 40, 44, 46, 50, 51, 52, 53, 107 💬