Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. 薬物名（臨床試験情報から抽出） DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1Adalimumab with methotrexate
(D02115)		1件: Adalimumab1件: Adalimumab 💬 1件: TNF 💬 66件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬1件: 46 💬
2Azathioprine or methotrexate
(D02115)		1件: Azathioprine2件: Azathioprine ,
Azathioprine sodium 💬 		--1件: 96 💬
3BMS-582949 and methotrexate
(D02115)		1件: BMS-582949---1件: 46 💬
4Busulfan/fludarabine phosphate/tacrolimus/methotrexate/G-CSF
(D02115)		1件: Busulfan1件: Busulfan 💬 --1件: 60 💬
5Clobetasol propionate + methotrexate
(D02115)		2件: Clobetasol,
Clobetasol propionate		2件: Clobetasol propionate ,
Clobetasol 💬 		1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬1件: 162 💬
6CP-690,550 + methotrexate
(D02115)		1件: Methotrexate2件: Methotrexate ,
Methotrexate sodium (D02115) 💬 		2件: DHFR,
DHFR 💬 		3件: Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬1件: 46 💬
7Cyclophosphamide followed BY methotrexate (azathioprine) + glucocorticoids or methotrexate (azathioprine) + glucocorticoids
(D02115)		1件: Cyclophosphamide2件: Cyclophosphamide ,
Cyclophosphamide 💬 		--1件: 44 💬
8Dmards (methotrexate
(D02115)		----1件: 46 💬
9Doxorubicin, methotrexate, cyclophosphamide, L-asparaginase
(D02115)		1件: Doxorubicin2件: Doxorubicin hydrochloride ,
Doxorubicin 💬 		--1件: 65 💬
10Etanercept + methotrexate
(D02115)		1件: Etanercept1件: Etanercept 💬 2件: LTA,
TNF 💬 		66件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬1件: 46 💬
11Etanercept , methotrexate
(D02115)		2件: Etanercept,
Methotrexate		3件: Methotrexate ,
Etanercept ,
Methotrexate sodium (D02115) 💬 		4件: DHFR,
DHFR,
LTA,
TNF 💬 		69件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Folate biosynthesis, Folate transport and metabolism, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, One carbon pool by folate, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬1件: 46 💬
12Etanercept, methotrexate and depomedrone
(D02115)		1件: Etanercept1件: Etanercept 💬 2件: LTA,
TNF 💬 		66件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬1件: 46 💬
13Etanercept, methotrexate, prednisolone
(D02115)		1件: Etanercept1件: Etanercept 💬 2件: LTA,
TNF 💬 		66件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬1件: 56 💬
14Infliximab plus methotrexate
(D02115)		2件: Infliximab,
Methotrexate		3件: Methotrexate ,
Methotrexate sodium (D02115),
Infliximab 💬 		3件: DHFR,
DHFR,
TNF 💬 		69件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Folate biosynthesis, Folate transport and metabolism, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, One carbon pool by folate, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬1件: 107 💬
15Infliximab, methylprednisolone, methotrexate
(D02115)		2件: Infliximab,
Methotrexate		3件: Methotrexate ,
Methotrexate sodium (D02115),
Infliximab 💬 		3件: DHFR,
DHFR,
TNF 💬 		69件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Folate biosynthesis, Folate transport and metabolism, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, One carbon pool by folate, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬1件: 46 💬
16Intrathecal methotrexate
(D02115)		----1件: 13 💬
17Laser, exercise, and methotrexate
(D02115)		1件: Methotrexate2件: Methotrexate ,
Methotrexate sodium (D02115) 💬 		2件: DHFR,
DHFR 💬 		3件: Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬1件: 46 💬
18Methotrexate
(D02115)		1件: Methotrexate2件: Methotrexate ,
Methotrexate sodium (D02115) 💬 		2件: DHFR,
DHFR 💬 		3件: Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬37件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 54, 55, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 284, 285, 286, 326, 331 💬
19Methotrexate 'lederle' 2,5MG tablets
(D02115)		1件: Methotrexate2件: Methotrexate ,
Methotrexate sodium (D02115) 💬 		2件: DHFR,
DHFR 💬 		3件: Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬1件: 46 💬
20Methotrexate 'lederle' 2.5MG tablets
(D02115)		1件: Methotrexate2件: Methotrexate ,
Methotrexate sodium (D02115) 💬 		2件: DHFR,
DHFR 💬 		3件: Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬1件: 46 💬
21Methotrexate 'lederle' tablets
(D02115)		1件: Methotrexate2件: Methotrexate ,
Methotrexate sodium (D02115) 💬 		2件: DHFR,
DHFR 💬 		3件: Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬1件: 46 💬
22Methotrexate (MTX)
(D02115)		1件: Methotrexate2件: Methotrexate ,
Methotrexate sodium (D02115) 💬 		2件: DHFR,
DHFR 💬 		3件: Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬1件: 46 💬
23Methotrexate + infliximab
(D02115)		2件: Infliximab,
Methotrexate		3件: Methotrexate ,
Methotrexate sodium (D02115),
Infliximab 💬 		3件: DHFR,
DHFR,
TNF 💬 		69件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Folate biosynthesis, Folate transport and metabolism, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, One carbon pool by folate, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬1件: 46 💬
24Methotrexate + methylprednisolone
(D02115)		1件: Methotrexate2件: Methotrexate ,
Methotrexate sodium (D02115) 💬 		2件: DHFR,
DHFR 💬 		3件: Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬1件: 46 💬
25Methotrexate + targeted therapy administration
(D02115)		1件: Methotrexate2件: Methotrexate ,
Methotrexate sodium (D02115) 💬 		2件: DHFR,
DHFR 💬 		3件: Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬1件: 46 💬
26Methotrexate - 20 MG/0.8 ML soluzione iniettabile 4 siringhe preriempite monouso DA 1.25 ML
(D02115)		1件: Methotrexate2件: Methotrexate ,
Methotrexate sodium (D02115) 💬 		2件: DHFR,
DHFR 💬 		3件: Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬1件: 96 💬
27Methotrexate - amneal
(D02115)		1件: Methotrexate2件: Methotrexate ,
Methotrexate sodium (D02115) 💬 		2件: DHFR,
DHFR 💬 		3件: Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬1件: 46 💬
28Methotrexate - dava
(D02115)		1件: Methotrexate2件: Methotrexate ,
Methotrexate sodium (D02115) 💬 		2件: DHFR,
DHFR 💬 		3件: Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬1件: 46 💬
29Methotrexate - delay
(D02115)		1件: Methotrexate2件: Methotrexate ,
Methotrexate sodium (D02115) 💬 		2件: DHFR,
DHFR 💬 		3件: Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬1件: 46 💬
30Methotrexate - etanercept - prednisolone ARM
(D02115)		1件: Methotrexate2件: Methotrexate ,
Methotrexate sodium (D02115) 💬 		2件: DHFR,
DHFR 💬 		3件: Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬2件: 46, 107 💬
31Methotrexate - immediate
(D02115)		1件: Methotrexate2件: Methotrexate ,
Methotrexate sodium (D02115) 💬 		2件: DHFR,
DHFR 💬 		3件: Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬1件: 46 💬
32Methotrexate 10 MG
(D02115)		1件: Methotrexate2件: Methotrexate ,
Methotrexate sodium (D02115) 💬 		2件: DHFR,
DHFR 💬 		3件: Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬1件: 46 💬
33Methotrexate 10 MG tablets
(D02115)		1件: Methotrexate2件: Methotrexate ,
Methotrexate sodium (D02115) 💬 		2件: DHFR,
DHFR 💬 		3件: Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬1件: 46 💬
34Methotrexate 2.5 MG
(D02115)		1件: Methotrexate2件: Methotrexate ,
Methotrexate sodium (D02115) 💬 		2件: DHFR,
DHFR 💬 		3件: Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬1件: 44 💬
35Methotrexate 2.5 MG tablets
(D02115)		1件: Methotrexate2件: Methotrexate ,
Methotrexate sodium (D02115) 💬 		2件: DHFR,
DHFR 💬 		3件: Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬1件: 46 💬
36Methotrexate 2.5MG tablets
(D02115)		1件: Methotrexate2件: Methotrexate ,
Methotrexate sodium (D02115) 💬 		2件: DHFR,
DHFR 💬 		3件: Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬1件: 46 💬
37Methotrexate 2.5MG tablets BP
(D02115)		1件: Methotrexate2件: Methotrexate ,
Methotrexate sodium (D02115) 💬 		2件: DHFR,
DHFR 💬 		3件: Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬1件: 46 💬
38Methotrexate 25 MG
(D02115)		1件: Methotrexate2件: Methotrexate ,
Methotrexate sodium (D02115) 💬 		2件: DHFR,
DHFR 💬 		3件: Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬1件: 44 💬
39Methotrexate 50MG/ML solution FOR injection, PRE-filled syringe
(D02115)		1件: Methotrexate2件: Methotrexate ,
Methotrexate sodium (D02115) 💬 		2件: DHFR,
DHFR 💬 		3件: Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬1件: 46 💬
40Methotrexate ``lederle`` 2.5MG tablets
(D02115)		1件: Methotrexate2件: Methotrexate ,
Methotrexate sodium (D02115) 💬 		2件: DHFR,
DHFR 💬 		3件: Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬1件: 46 💬
41Methotrexate alone
(D02115)		1件: Methotrexate2件: Methotrexate ,
Methotrexate sodium (D02115) 💬 		2件: DHFR,
DHFR 💬 		3件: Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬1件: 107 💬
42Methotrexate and folic acid
(D02115)		1件: Methotrexate2件: Methotrexate ,
Methotrexate sodium (D02115) 💬 		2件: DHFR,
DHFR 💬 		3件: Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬1件: 49 💬
43Methotrexate AS methotrexate disodium
(D02115)		1件: Methotrexate2件: Methotrexate ,
Methotrexate sodium (D02115) 💬 		2件: DHFR,
DHFR 💬 		3件: Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬1件: 46 💬
44Methotrexate bellon 25MG/ML
(D02115)		1件: Methotrexate2件: Methotrexate ,
Methotrexate sodium (D02115) 💬 		2件: DHFR,
DHFR 💬 		3件: Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬1件: 97 💬
45Methotrexate capsules
(D02115)		1件: Methotrexate2件: Methotrexate ,
Methotrexate sodium (D02115) 💬 		2件: DHFR,
DHFR 💬 		3件: Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬1件: 46 💬
46Methotrexate combined with tofacitinib
(D02115)		1件: Methotrexate2件: Methotrexate ,
Methotrexate sodium (D02115) 💬 		2件: DHFR,
DHFR 💬 		3件: Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬1件: 46 💬
47Methotrexate disodium
(D02115)		1件: Methotrexate2件: Methotrexate ,
Methotrexate sodium (D02115) 💬 		2件: DHFR,
DHFR 💬 		3件: Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬5件: 46, 96, 97, 107, 271 💬
48Methotrexate ebewe
(D02115)		1件: Methotrexate2件: Methotrexate ,
Methotrexate sodium (D02115) 💬 		2件: DHFR,
DHFR 💬 		3件: Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬1件: 46 💬
49Methotrexate hospira 2,5 MG tablety
(D02115)		1件: Methotrexate2件: Methotrexate ,
Methotrexate sodium (D02115) 💬 		2件: DHFR,
DHFR 💬 		3件: Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬1件: 46 💬
50Methotrexate hospira 2.5 MG tablety
(D02115)		1件: Methotrexate2件: Methotrexate ,
Methotrexate sodium (D02115) 💬 		2件: DHFR,
DHFR 💬 		3件: Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬1件: 46 💬
51Methotrexate injection
(D02115)		1件: Methotrexate2件: Methotrexate ,
Methotrexate sodium (D02115) 💬 		2件: DHFR,
DHFR 💬 		3件: Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬2件: 96, 97 💬
52Methotrexate lachema 5INJ. SOL
(D02115)		1件: Methotrexate2件: Methotrexate ,
Methotrexate sodium (D02115) 💬 		2件: DHFR,
DHFR 💬 		3件: Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬1件: 50 💬
53Methotrexate lederle 2.5 MG tablets
(D02115)		1件: Methotrexate2件: Methotrexate ,
Methotrexate sodium (D02115) 💬 		2件: DHFR,
DHFR 💬 		3件: Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬1件: 46 💬
54Methotrexate or leflunomide + sulfasalazine + hydroxychloroquine administration
(D02115)		1件: Methotrexate2件: Methotrexate ,
Methotrexate sodium (D02115) 💬 		2件: DHFR,
DHFR 💬 		3件: Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬1件: 46 💬
55Methotrexate pfizer 2,5 MG tabletter
(D02115)		1件: Methotrexate2件: Methotrexate ,
Methotrexate sodium (D02115) 💬 		2件: DHFR,
DHFR 💬 		3件: Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬1件: 46 💬
56Methotrexate plus enbrel or enbrel alone
(D02115)		1件: Methotrexate2件: Methotrexate ,
Methotrexate sodium (D02115) 💬 		2件: DHFR,
DHFR 💬 		3件: Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬1件: 46 💬
57Methotrexate plus ERB-041 FOR 12 weeks
(D02115)		1件: Methotrexate2件: Methotrexate ,
Methotrexate sodium (D02115) 💬 		2件: DHFR,
DHFR 💬 		3件: Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬1件: 46 💬
58Methotrexate plus sulfasalazine
(D02115)		1件: Methotrexate2件: Methotrexate ,
Methotrexate sodium (D02115) 💬 		2件: DHFR,
DHFR 💬 		3件: Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬1件: 46 💬
59Methotrexate PRE-filled PEN
(D02115)		1件: Methotrexate2件: Methotrexate ,
Methotrexate sodium (D02115) 💬 		2件: DHFR,
DHFR 💬 		3件: Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬1件: 46 💬
60Methotrexate prefilled PEN
(D02115)		1件: Methotrexate2件: Methotrexate ,
Methotrexate sodium (D02115) 💬 		2件: DHFR,
DHFR 💬 		3件: Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬2件: 46, 107 💬
61Methotrexate prefilled syringe
(D02115)		1件: Methotrexate2件: Methotrexate ,
Methotrexate sodium (D02115) 💬 		2件: DHFR,
DHFR 💬 		3件: Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬1件: 46 💬
62Methotrexate sodium
(D02115)		1件: Methotrexate2件: Methotrexate ,
Methotrexate sodium (D02115) 💬 		2件: DHFR,
DHFR 💬 		3件: Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬2件: 46, 256 💬
63Methotrexate sodium 2.5MG tablets
(D02115)		1件: Methotrexate2件: Methotrexate ,
Methotrexate sodium (D02115) 💬 		2件: DHFR,
DHFR 💬 		3件: Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬1件: 46 💬
64Methotrexate sodium tablets 2.5 MG
(D02115)		1件: Methotrexate2件: Methotrexate ,
Methotrexate sodium (D02115) 💬 		2件: DHFR,
DHFR 💬 		3件: Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬1件: 46 💬
65Methotrexate sodium tablets 2.5MG
(D02115)		1件: Methotrexate2件: Methotrexate ,
Methotrexate sodium (D02115) 💬 		2件: DHFR,
DHFR 💬 		3件: Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬1件: 46 💬
66Methotrexate tablets
(D02115)		1件: Methotrexate2件: Methotrexate ,
Methotrexate sodium (D02115) 💬 		2件: DHFR,
DHFR 💬 		3件: Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬2件: 40, 46 💬
67Methotrexate tablets 2.5 MG
(D02115)		1件: Methotrexate2件: Methotrexate ,
Methotrexate sodium (D02115) 💬 		2件: DHFR,
DHFR 💬 		3件: Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬1件: 46 💬
68Methotrexate therapy
(D02115)		1件: Methotrexate2件: Methotrexate ,
Methotrexate sodium (D02115) 💬 		2件: DHFR,
DHFR 💬 		3件: Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬1件: 46 💬
69Methotrexate treatment
(D02115)		1件: Methotrexate2件: Methotrexate ,
Methotrexate sodium (D02115) 💬 		2件: DHFR,
DHFR 💬 		3件: Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬2件: 41, 46 💬
70Methotrexate wyeth 2,5MG
(D02115)		1件: Methotrexate2件: Methotrexate ,
Methotrexate sodium (D02115) 💬 		2件: DHFR,
DHFR 💬 		3件: Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬1件: 50 💬
71Methotrexate ® 2.5MG tablets
(D02115)		1件: Methotrexate2件: Methotrexate ,
Methotrexate sodium (D02115) 💬 		2件: DHFR,
DHFR 💬 		3件: Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬1件: 46 💬
72Methotrexate*100CPR 2,5MG
(D02115)		1件: Methotrexate2件: Methotrexate ,
Methotrexate sodium (D02115) 💬 		2件: DHFR,
DHFR 💬 		3件: Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬1件: 46 💬
73Methotrexate*10MG/1,33ML 4S
(D02115)		1件: Methotrexate2件: Methotrexate ,
Methotrexate sodium (D02115) 💬 		2件: DHFR,
DHFR 💬 		3件: Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬1件: 46 💬
74Methotrexate*15MG/2ML 4SIR
(D02115)		1件: Methotrexate2件: Methotrexate ,
Methotrexate sodium (D02115) 💬 		2件: DHFR,
DHFR 💬 		3件: Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬1件: 46 💬
75Methotrexate*2,5MG 25CPR
(D02115)		1件: Methotrexate2件: Methotrexate ,
Methotrexate sodium (D02115) 💬 		2件: DHFR,
DHFR 💬 		3件: Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬1件: 46 💬
76Methotrexate*20MG/2,66ML 4S
(D02115)		1件: Methotrexate2件: Methotrexate ,
Methotrexate sodium (D02115) 💬 		2件: DHFR,
DHFR 💬 		3件: Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬1件: 46 💬
77Methotrexate*25CPR 2,5MG
(D02115)		1件: Methotrexate2件: Methotrexate ,
Methotrexate sodium (D02115) 💬 		2件: DHFR,
DHFR 💬 		3件: Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬2件: 46, 107 💬
78Methotrexate, leucovorin and BMS-986142
(D02115)		1件: Methotrexate2件: Methotrexate ,
Methotrexate sodium (D02115) 💬 		2件: DHFR,
DHFR 💬 		3件: Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬1件: 46 💬
79Methotrexate-lachema
(D02115)		1件: Methotrexate2件: Methotrexate ,
Methotrexate sodium (D02115) 💬 		2件: DHFR,
DHFR 💬 		3件: Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬1件: 46 💬
80Methotrexate-sulfasalazine-hydroxychloroquine
(D02115)		1件: Methotrexate2件: Methotrexate ,
Methotrexate sodium (D02115) 💬 		2件: DHFR,
DHFR 💬 		3件: Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬1件: 46 💬
81Methotrexate® 2.5 MG tablets
(D02115)		1件: Methotrexate2件: Methotrexate ,
Methotrexate sodium (D02115) 💬 		2件: DHFR,
DHFR 💬 		3件: Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬1件: 46 💬
82Modified zhiwang decoction combined with methotrexate
(D02115)		1件: Methotrexate2件: Methotrexate ,
Methotrexate sodium (D02115) 💬 		2件: DHFR,
DHFR 💬 		3件: Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬1件: 46 💬
83MP-435(DOSE1) + methotrexate
(D02115)		1件: Methotrexate2件: Methotrexate ,
Methotrexate sodium (D02115) 💬 		2件: DHFR,
DHFR 💬 		3件: Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬1件: 46 💬
84Mycophenolate mofetil,methotrexate
(D02115)		2件: Mycophenolate mofetil,
Mycophenolic acid		4件: Mycophenolate mofetil ,
Mycophenolate mofetil hydrochloride ,
Mycophenolate sodium ,
Mycophenolic acid 💬 		2件: IMPDH,
IMPDH 💬 		2件: Drug metabolism - other enzymes, Purine metabolism 💬3件: 42, 43, 45 💬
85Oral methotrexate
(D02115)		1件: Methotrexate2件: Methotrexate ,
Methotrexate sodium (D02115) 💬 		2件: DHFR,
DHFR 💬 		3件: Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬1件: 46 💬
86Phase 1: methotrexate
(D02115)		----1件: 46 💬
87Response TO anakinra associated with methotrexate
(D02115)		----1件: 46 💬
88Response TO infliximab associated with methotrexate
(D02115)		----1件: 46 💬
89Stable weekly dose OF methotrexate
(D02115)		----1件: 46 💬
90Tacrolimus with methotrexate
(D02115)		1件: Tacrolimus2件: Tacrolimus ,
Tacrolimus 💬 		5件: PPP3C,
PPP3C,
PPP3C,
PPP3R,
PPP3R 💬 		33件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬1件: 46 💬
91TAK-715 and methotrexate
(D02115)		2件: Methotrexate,
TAK-715		2件: Methotrexate ,
Methotrexate sodium (D02115) 💬 		2件: DHFR,
DHFR 💬 		3件: Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬1件: 46 💬
92TAK-783 and methotrexate
(D02115)		1件: Methotrexate2件: Methotrexate ,
Methotrexate sodium (D02115) 💬 		2件: DHFR,
DHFR 💬 		3件: Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬1件: 46 💬
93Tasocitinib plus methotrexate
(D02115)		2件: Methotrexate,
Tofacitinib		4件: Methotrexate ,
Methotrexate sodium (D02115),
Tofacitinib citrate ,
Tofacitinib 💬 		6件: DHFR,
DHFR,
JAK1,
JAK2,
JAK3,
TYK2 💬 		42件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, Efferocytosis, Epstein-Barr virus infection, Folate biosynthesis, Folate transport and metabolism, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Hormone signaling, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, One carbon pool by folate, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬1件: 46 💬
94Tocilizumab plus methotrexate
(D02115)		2件: Methotrexate,
Tocilizumab		3件: Methotrexate ,
Methotrexate sodium (D02115),
Tocilizumab 💬 		3件: DHFR,
DHFR,
IL6R 💬 		14件: Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Folate biosynthesis, Folate transport and metabolism, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, One carbon pool by folate, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬1件: 46 💬
95Tofacitinib with methotrexate
(D02115)		1件: Tofacitinib2件: Tofacitinib citrate ,
Tofacitinib 💬 		4件: JAK1,
JAK2,
JAK3,
TYK2 💬 		39件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, Efferocytosis, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Hormone signaling, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬1件: 46 💬
96Tofacitinib without methotrexate
(D02115)		1件: Tofacitinib2件: Tofacitinib citrate ,
Tofacitinib 💬 		4件: JAK1,
JAK2,
JAK3,
TYK2 💬 		39件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, Efferocytosis, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Hormone signaling, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬1件: 46 💬
97Urine samples taken TO measure methotrexate and ITS major metabolite 7-OH-methotrexate level
(D02115)		----1件: 46 💬