Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank 薬物名（臨床試験情報から抽出） KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Ataluren 1件: Ataluren1件: Ataluren 💬 --6件: 19, 113, 140, 246, 299, 329 💬
2 Cannabidiol 1件: Cannabidiol1件: Cannabidiol 💬 2件: CNR1,
CNR2 💬 		4件: Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬20件: 6, 8, 13, 19, 36, 46, 51, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬
3 Carbidopa 1件: Carbidopa1件: Carbidopa 💬 1件: DDC 💬 8件: Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬5件: 6, 13, 17, 140, 201 💬
4 Clemizole 1件: Clemizole hydrochloride2件: Clemizole hydrochloride ,
Clemizole 💬 		1件: TRPC5 💬 2件: Axon guidance, GnRH secretion 💬2件: 140, 144 💬
5 Clobazam 1件: Clobazam1件: Clobazam 💬 16件: GABRA,
GABRA,
GABRA,
GABRA,
GABRA,
GABRA,
GABRB,
GABRB,
GABRB,
GABRD,
GABRE,
GABRG,
GABRG,
GABRG,
GABRP,
GABRQ 💬 		8件: GABAergic synapse, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬2件: 140, 144 💬
6 ETX101 1件: ETX101---1件: 140 💬
7 Fenfluramine 2件: Fenfluramine; Fenfluramine hydrochloride2件: Fenfluramine hydrochloride ,
Fenfluramine 💬 		5件: HTR1,
HTR2,
HTR2,
SIGMAR1,
SLC6A4 💬 		11件: Amyotrophic lateral sclerosis, Calcium signaling pathway, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Pathways of neurodegeneration - multiple diseases, Serotonergic synapse, Synaptic vesicle cycle, Taste transduction, cAMP signaling pathway 💬4件: 140, 144, 145, 149 💬
8 gamma-Aminobutyric acid 0件: 1件: gamma-Aminobutyric acid 💬 18件: GABBR,
GABBR,
GABRA,
GABRA,
GABRA,
GABRA,
GABRA,
GABRA,
GABRB,
GABRB,
GABRB,
GABRD,
GABRE,
GABRG,
GABRG,
GABRG,
GABRP,
GABRQ 💬 		11件: Estrogen signaling pathway, GABAergic synapse, GnRH secretion, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, cAMP signaling pathway 💬1件: 140 💬
9 Levodopa 2件: L-dopa; Levodopa1件: Levodopa 💬 5件: DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬 		13件: Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬6件: 6, 17, 90, 140, 164, 201 💬
10 Lorcaserin 1件: Lorcaserin2件: Lorcaserin hydrochloride ,
Lorcaserin hydrochloride hemihydrate 💬 		1件: HTR2 💬 6件: Calcium signaling pathway, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Serotonergic synapse 💬1件: 140 💬
11 Methyl isocyanate 0件: ---2件: 140, 144 💬
12 Soticlestat 1件: Soticlestat1件: Soticlestat 💬 1件: CYP46A1 💬 1件: Primary bile acid biosynthesis 💬2件: 140, 144 💬
13 Stiripentol 1件: Stiripentol1件: Stiripentol 💬 --2件: 140, 234 💬
14 Topiramate 1件: Topiramate1件: Topiramate 💬 36件: CA2,
CA4,
CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S,
GABRA,
GABRA,
GABRA,
GABRA,
GABRA,
GABRA,
GABRB,
GABRB,
GABRB,
GABRD,
GABRE,
GABRG,
GABRG,
GABRG,
GABRP,
GABRQ,
GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬 		53件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Arrhythmogenic right ventricular cardiomyopathy, Bile secretion, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Collecting duct acid secretion, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Gastric acid secretion, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Huntington disease, Hypertrophic cardiomyopathy, Insulin secretion, Long-term depression, Long-term potentiation, MAPK signaling pathway, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Nitrogen metabolism, Oxytocin signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Prion disease, Proximal tubule bicarbonate reclamation, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Spinocerebellar ataxia, Taste transduction, Tight junction, Transcriptional misregulation in cancer, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬5件: 6, 140, 144, 156, 193 💬
15 Turmeric 1件: Turmeric---5件: 96, 140, 144, 158, 299 💬
16 Verapamil 2件: Verapamil; Verapamil hydrochloride2件: Verapamil hydrochloride ,
Verapamil 💬 		4件: CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬 		37件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬4件: 58, 96, 140, 167 💬
17 Zorevunersen 2件: STK-001; Zorevunersen---1件: 140 💬