Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank 薬物名（臨床試験情報から抽出） KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Sacubitril 1件: Sacubitril1件: Sacubitril 💬 1件: MME 💬 4件: Alzheimer disease, Hematopoietic cell lineage, Protein digestion and absorption, Renin-angiotensin system 💬3件: 58, 210, 222 💬
2 Safinamide 2件: Safinamida; Safinamide2件: Safinamide ,
Safinamide mesylate 💬 		1件: MAO 💬 13件: Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬2件: 6, 17 💬
3 Sage 0件: ---1件: 6 💬
4 Salmeterol 1件: Salmeterol2件: Salmeterol xinafoate ,
Salmeterol 💬 		1件: ADRB2 💬 11件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 299 💬
5 Salmon, unspecified 1件: Salmon---3件: 96, 97, 225 💬
6 Salsalate 1件: Salsalate1件: Salsalate 💬 2件: PTGS1,
PTGS2 💬 		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬1件: 5 💬
7 Sapropterin 4件: 6R-BH4; Sapropterin; Sapropterin dihydrochloride; Tetrahydrobiopterin2件: Sapropterin dihydrochloride ,
Sapropterin 💬 		--3件: 86, 124, 240 💬
8 Saquinavir 1件: Saquinavir2件: Saquinavir ,
Saquinavir mesylate 💬 		--2件: 86, 265 💬
9 SAR421869 1件: SAR421869---2件: 90, 303 💬
10 SAR422459 1件: SAR422459---1件: 301 💬
11 SAR443122 1件: SAR4431221件: Eclitasertib 💬 1件: RIPK1 💬 16件: Alcoholic liver disease, Apoptosis, Cytosolic DNA-sensing pathway, Epstein-Barr virus infection, Hepatitis C, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Necroptosis, Pathogenic Escherichia coli infection, RIG-I-like receptor signaling pathway, Salmonella infection, Shigellosis, TNF signaling pathway, Toll-like receptor signaling pathway 💬1件: 97 💬
12 Saracatinib 1件: Saracatinib1件: Saracatinib 💬 2件: ABL1,
SRC 💬 		48件: Adherens junction, Axon guidance, Bacterial invasion of epithelial cells, Bladder cancer, C-type lectin receptor signaling pathway, Cell cycle, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Chronic myeloid leukemia, Endocytosis, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Fluid shear stress and atherosclerosis, Focal adhesion, GABAergic synapse, Gap junction, GnRH signaling pathway, Hepatitis B, Herpes simplex virus 1 infection, Hormone signaling, Human cytomegalovirus infection, Inflammatory mediator regulation of TRP channels, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, MicroRNAs in cancer, Mitophagy - animal, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Oxytocin signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Platelet activation, Prolactin signaling pathway, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Thyroid hormone signaling pathway, Tight junction, Tuberculosis, VEGF signaling pathway, Viral carcinogenesis, Viral myocarditis, Yersinia infection 💬3件: 6, 89, 272 💬
13 Sarcosine 0件: ---1件: 6 💬
14 Sargramostim 1件: Sargramostim1件: Sargramostim 💬 1件: CSF2RA 💬 4件: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, Pathways in cancer 💬7件: 6, 28, 60, 62, 96, 229, 285 💬
15 Sarilumab 3件: REGN88; SAR153191; Sarilumab1件: Sarilumab 💬 1件: IL6R 💬 11件: Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬5件: 41, 46, 84, 107, 271 💬
16 Sarizotan 2件: Sarizotan; Sarizotan hydrochloride1件: Sarizotan hydrochloride 💬 2件: DRD2,
HTR1 💬 		12件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, Taste transduction, cAMP signaling pathway 💬2件: 6, 156 💬
17 Saroglitazar 0件: 2件: Saroglitazar ,
Saroglitazar magnesium 💬 		3件: NR1C1,
NR1C2,
NR1C3 💬 		22件: AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Efferocytosis, Glucagon signaling pathway, Hepatitis C, Huntington disease, Insulin resistance, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer, Wnt signaling pathway, cAMP signaling pathway 💬1件: 93 💬
18 SARS-CoV-2 mRNA vaccine 1件: SARS-COV-2 mrna vaccine---1件: 13 💬
19 Satavaptan 1件: Satavaptan---1件: 72 💬
20 Satralizumab 2件: Sapelizumab; Satralizumab1件: Satralizumab 💬 1件: IL6R 💬 11件: Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬4件: 11, 13, 86, 113 💬
21 Saxagliptin 1件: Saxagliptin2件: Saxagliptin ,
Saxagliptin hydrochloride 💬 		1件: DPP4 💬 2件: Protein digestion and absorption, Virion - Hepatitis viruses 💬1件: 299 💬
22 SB-509 1件: SB-509---1件: 2 💬
23 SBT101 1件: SBT101---1件: 20 💬
24 SC12267 1件: SC12267---3件: 46, 96, 97 💬
25 Scopolamine 1件: Scopolamine1件: Scopolamine 💬 5件: CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬 		14件: Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬1件: 2 💬
26 Scutellaria baicalensis root 1件: Scutellaria baicalensis1件: Scutellaria root 💬 --1件: 224 💬
27 Sebelipase alfa 2件: SBC-102; Sebelipase alfa1件: Sebelipase alfa 💬 1件: LIPA 💬 4件: Cholesterol metabolism, Efferocytosis, Lysosome, Steroid biosynthesis 💬1件: 19 💬
28 Sebetralstat 1件: Sebetralstat1件: Sebetralstat 💬 1件: KLKB1 💬 1件: Complement and coagulation cascades 💬1件: 65 💬
29 Secretin human 2件: Human secretin; Secretin1件: Secretin 💬 1件: SCTR 💬 3件: Bile secretion, Neuroactive ligand-receptor interaction, Pancreatic secretion 💬1件: 298 💬
30 Secukinumab 1件: Secukinumab1件: Secukinumab 💬 1件: IL17A 💬 6件: Alcoholic liver disease, Cytokine-cytokine receptor interaction, IL-17 signaling pathway, Inflammatory bowel disease, Rheumatoid arthritis, Th17 cell differentiation 💬8件: 13, 37, 41, 46, 107, 160, 269, 271 💬
31 SEL-302 1件: SEL-302---1件: 246 💬
32 Seladelpar 1件: Seladelpar2件: Seladelpar ,
Seladelpar lysine 💬 		1件: NR1C3 💬 12件: AMPK signaling pathway, Efferocytosis, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬2件: 93, 94 💬
33 Selegiline 1件: Selegiline2件: Selegiline hydrochloride ,
Selegiline 💬 		1件: MAO 💬 13件: Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬1件: 6 💬
34 Selenium 1件: Selenium---4件: 13, 96, 278, 298 💬
35 Selexipag 1件: Selexipag1件: Selexipag 💬 1件: PTGIR 💬 3件: Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬6件: 47, 51, 70, 84, 86, 88 💬
36 Seliciclib 2件: R-roscovitine; Seliciclib---2件: 75, 299 💬
37 Selinexor 1件: Selinexor1件: Selinexor 💬 1件: XPO1 💬 5件: Human T-cell leukemia virus 1 infection, Influenza A, Nucleocytoplasmic transport, Ribosome biogenesis in eukaryotes, Viral life cycle - HIV-1 💬1件: 28 💬
38 Selisistat 1件: Selisistat---1件: 8 💬
39 Selonsertib 1件: Selonsertib1件: Selonsertib 💬 1件: MAP3K5 💬 19件: Alcoholic liver disease, Alzheimer disease, Amyotrophic lateral sclerosis, Apoptosis, Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Huntington disease, Lipid and atherosclerosis, MAPK signaling pathway, Neurotrophin signaling pathway, Non-alcoholic fatty liver disease, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Protein processing in endoplasmic reticulum, Sphingolipid signaling pathway, Spinocerebellar ataxia, TNF signaling pathway, Thermogenesis, Tight junction 💬1件: 86 💬
40 Selumetinib 2件: Selumetinib; Selumetinib sulfate2件: Selumetinib ,
Selumetinib sulfate 💬 		2件: MAP2K1,
MAP2K2 💬 		88件: Acute myeloid leukemia, Alcoholism, Alzheimer disease, Apelin signaling pathway, Apoptosis, Autophagy - animal, B cell receptor signaling pathway, Bladder cancer, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Choline metabolism in cancer, Cholinergic synapse, Chronic myeloid leukemia, Colorectal cancer, Cushing syndrome, Efferocytosis, Endometrial cancer, ErbB signaling pathway, Estrogen signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatitis B, Hepatitis C, Hepatocellular carcinoma, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Influenza A, Insulin signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Long-term depression, Long-term potentiation, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-small cell lung cancer, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Renal cell carcinoma, Salmonella infection, Serotonergic synapse, Signaling pathways regulating pluripotency of stem cells, Sphingolipid signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Thyroid cancer, Thyroid hormone signaling pathway, Toll-like receptor signaling pathway, VEGF signaling pathway, Vascular smooth muscle contraction, Yersinia infection, cAMP signaling pathway, cGMP-PKG signaling pathway, mTOR signaling pathway 💬1件: 34 💬
41 Semaglutide 1件: Semaglutide1件: Semaglutide 💬 1件: GLP1R 💬 4件: Hormone signaling, Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬4件: 6, 51, 84, 299 💬
42 Semapimod 1件: Semapimod---1件: 96 💬
43 Senicapoc 1件: Senicapoc1件: Senicapoc 💬 1件: KCNN4 💬 4件: GnRH secretion, Insulin secretion, Protein digestion and absorption, Salivary secretion 💬1件: 85 💬
44 Senna leaf 1件: Senna2件: Senna ,
Senna leaf 💬 		--1件: 291 💬
45 SEP-363856 1件: SEP-363856---1件: 6 💬
46 Sepiapterin 1件: Sepiapterin1件: Sepiapterin 💬 --1件: 240 💬
47 SER-287 1件: SER-287---1件: 97 💬
48 Seralutinib 1件: Seralutinib1件: Seralutinib 💬 2件: PDGFRA,
PDGFRB 💬 		20件: Calcium signaling pathway, Central carbon metabolism in cancer, Choline metabolism in cancer, Endocytosis, Focal adhesion, Gap junction, Glioma, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, PI3K-Akt signaling pathway, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton 💬1件: 86 💬
49 Serine 1件: Serine1件: Serine 💬 --1件: 86 💬
50 Serlopitant 0件: 1件: Serlopitant 💬 1件: TACR1 💬 3件: Calcium signaling pathway, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬1件: 36 💬
51 Serotonin 1件: Serotonin---1件: 2 💬
52 Sertraline 1件: Sertraline2件: Sertraline hydrochloride ,
Sertraline 💬 		1件: SLC6A4 💬 3件: Neuroactive ligand signaling, Serotonergic synapse, Synaptic vesicle cycle 💬3件: 6, 158, 206 💬
53 Sesame oil 0件: 1件: Sesame oil 💬 --1件: 3 💬
54 Setanaxib 1件: Setanaxib---2件: 93, 218 💬
55 Setmelanotide 1件: Setmelanotide2件: Setmelanotide ,
Setmelanotide acetate 💬 		1件: MC4R 💬 3件: Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬4件: 134, 193, 202, 265 💬
56 Setrusumab 1件: Setrusumab1件: Setrusumab 💬 1件: SOST 💬 2件: Parathyroid hormone synthesis, secretion and action, Wnt signaling pathway 💬1件: 274 💬
57 Sevasemten 1件: Sevasemten1件: Sevasemten 💬 8件: MYH1s,
MYH1s,
MYH1s,
MYH1s,
MYH1s,
MYH1s,
MYH1s,
MYH1s 💬 		2件: Cytoskeleton in muscle cells, Motor proteins 💬1件: 113 💬
58 Sevelamer 1件: Sevelamer3件: Sevelamer hydrochloride ,
Sevelamer carbonate ,
Sevelamer 💬 		--2件: 235, 238 💬
59 Sevoflurane 1件: Sevoflurane1件: Sevoflurane 💬 --8件: 6, 21, 22, 34, 70, 98, 225, 296 💬
60 Sibeprenlimab 1件: Sibeprenlimab1件: Sibeprenlimab 💬 1件: TNFSF13 💬 3件: Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, Rheumatoid arthritis 💬1件: 66 💬
61 Sibofimloc 1件: Sibofimloc1件: Sibofimloc 💬 --1件: 96 💬
62 Sifalimumab 1件: Sifalimumab1件: Sifalimumab 💬 13件: IFNA,
IFNA,
IFNA,
IFNA,
IFNA,
IFNA,
IFNA,
IFNA,
IFNA,
IFNA,
IFNA,
IFNA,
IFNA 💬 		25件: Alcoholic liver disease, Autoimmune thyroid disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, PI3K-Akt signaling pathway, Pathways in cancer, RIG-I-like receptor signaling pathway, Toll-like receptor signaling pathway, Tuberculosis 💬1件: 49 💬
63 Sildenafil 3件: Sildenafil; Sildenafil citrate; Sildenafilo2件: Sildenafil citrate ,
Sildenafil 💬 		1件: PDE5 💬 2件: Purine metabolism, cGMP-PKG signaling pathway 💬14件: 6, 46, 51, 85, 86, 113, 210, 211, 212, 225, 226, 278, 294, 299 💬
64 Silodosin 1件: Silodosin1件: Silodosin 💬 1件: ADRA1A 💬 9件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬1件: 6 💬
65 Siltuximab 1件: Siltuximab1件: Siltuximab 💬 1件: IL6 💬 49件: AGE-RAGE signaling pathway in diabetic complications, African trypanosomiasis, Alcoholic liver disease, Alzheimer disease, Amoebiasis, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Epstein-Barr virus infection, FoxO signaling pathway, Graft-versus-host disease, HIF-1 signaling pathway, Hematopoietic cell lineage, Hepatitis B, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Lipid and atherosclerosis, Malaria, Measles, NOD-like receptor signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Rheumatoid arthritis, Salmonella infection, TNF signaling pathway, Th17 cell differentiation, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Tuberculosis, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection 💬2件: 28, 331 💬
66 Silver 1件: Silver---2件: 35, 162 💬
67 Simethicone 1件: Simethicone1件: Simethicone 💬 --2件: 13, 96 💬
68 Simtuzumab 2件: GS-6624; Simtuzumab---2件: 85, 94 💬
69 Simvastatin 2件: Simvastatin; Simvastatine1件: Simvastatin 💬 1件: HMGCR 💬 3件: AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬21件: 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
70 Sinecatechins 1件: Polyphenon E1件: Sinecatechins 💬 --3件: 13, 36, 97 💬
71 Sinomenine 1件: Sinomenine---2件: 46, 222 💬
72 Siplizumab 1件: Siplizumab1件: Siplizumab 💬 1件: CD2 💬 2件: Cell adhesion molecules, Hematopoietic cell lineage 💬2件: 94, 95 💬
73 Siponimod 1件: Siponimod2件: Siponimod fumarate ,
Siponimod 💬 		2件: S1PR1,
S1PR5 💬 		4件: Efferocytosis, FoxO signaling pathway, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway 💬2件: 13, 50 💬
74 Sirolimus 2件: Rapamycin; Sirolimus1件: Sirolimus 💬 1件: MTOR 💬 49件: AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬46件: 2, 6, 13, 15, 17, 19, 21, 34, 35, 36, 46, 48, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 97, 98, 137, 157, 158, 192, 193, 222, 227, 256, 277, 278, 279, 280, 281, 283, 285, 300, 331 💬
75 Sirukumab 1件: Sirukumab1件: Sirukumab 💬 1件: IL6 💬 49件: AGE-RAGE signaling pathway in diabetic complications, African trypanosomiasis, Alcoholic liver disease, Alzheimer disease, Amoebiasis, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Epstein-Barr virus infection, FoxO signaling pathway, Graft-versus-host disease, HIF-1 signaling pathway, Hematopoietic cell lineage, Hepatitis B, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Lipid and atherosclerosis, Malaria, Measles, NOD-like receptor signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Rheumatoid arthritis, Salmonella infection, TNF signaling pathway, Th17 cell differentiation, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Tuberculosis, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection 💬2件: 41, 46 💬
76 Sitagliptin 1件: Sitagliptin3件: Sitagliptin phosphate ,
Sitagliptin ,
Sitagliptin phosphate 💬 		1件: DPP4 💬 2件: Protein digestion and absorption, Virion - Hepatitis viruses 💬5件: 6, 75, 77, 233, 299 💬
77 Sitaxentan 3件: Sitaxentan; Sitaxentan sodium; Sitaxsentan2件: Sitaxentan ,
Sitaxentan sodium 💬 		1件: EDNRA 💬 7件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 86 💬
78 Sivelestat 1件: Sivelestat1件: Sivelestat 💬 1件: ELANE 💬 3件: Neutrophil extracellular trap formation, Systemic lupus erythematosus, Transcriptional misregulation in cancer 💬3件: 13, 85, 96 💬
79 Skin-derived ABCB5-positive Mesenchymal Stem cells 1件: ALLO-APZ2-EB---1件: 36 💬
80 Smilagenin 1件: Smilagenin---1件: 6 💬
81 SNSP113 1件: SNSP113---1件: 299 💬
82 Sobetirome 1件: Sobetirome1件: Sobetirome 💬 1件: THRB 💬 3件: Hormone signaling, Neuroactive ligand-receptor interaction, Thyroid hormone signaling pathway 💬1件: 20 💬
83 Sodium acetate 1件: Sodium acetate1件: Sodium acetate 💬 --1件: 251 💬
84 Sodium ascorbate 1件: Sodium ascorbate1件: Sodium ascorbate 💬 --1件: 97 💬
85 Sodium aurothiomalate 1件: Sodium aurothiomalate1件: Gold sodium thiomalate 💬 --1件: 46 💬
86 Sodium bicarbonate 1件: Sodium bicarbonate1件: Sodium bicarbonate 💬 --4件: 67, 97, 226, 299 💬
87 Sodium chloride 2件: Natriumchlorid; Sodium chloride1件: Sodium chloride 💬 --23件: 2, 11, 13, 14, 34, 41, 46, 51, 53, 60, 67, 70, 96, 97, 193, 214, 215, 226, 227, 228, 288, 298, 299 💬
88 Sodium citrate 1件: Sodium citrate2件: Sodium citrate hydrate ,
Sodium citrate 💬 		--4件: 67, 214, 215, 235 💬
89 Sodium dichloroacetate 1件: Dichloroacetate sodium---1件: 86 💬
90 Sodium fluoride 0件: 1件: Sodium fluoride 💬 --1件: 51 💬
91 Sodium lauryl sulfate 0件: 1件: Sodium lauryl sulfate 💬 --1件: 2 💬
92 Sodium nitrate 1件: Sodium nitrate---2件: 58, 113 💬
93 Sodium oxybate 1件: Sodium oxybate1件: Sodium oxybate 💬 --2件: 6, 149 💬
94 Sodium sulfate 1件: Sodium sulphate anhydrous2件: Anhydous sodium sulfate ,
Sodium sulfate 💬 		--1件: 97 💬
95 Sodium tetradecyl sulfate 0件: 1件: Sodium tetradecyl sulfate 💬 --3件: 50, 51, 52 💬
96 Solifenacin 2件: Solifenacin; Solifenacin succinate2件: Solifenacin succinate ,
Solifenacin 💬 		1件: CHRM3 💬 12件: Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction 💬2件: 6, 13 💬
97 Solriamfetol 1件: Solriamfetol2件: Solriamfetol ,
Solriamfetol hydrochloride 💬 		2件: SLC6A2,
SLC6A3 💬 		8件: Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Neuroactive ligand signaling, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬1件: 13 💬
98 Solrikitug 0件: 1件: Solrikitug 💬 1件: TSLPR 💬 2件: Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway 💬1件: 98 💬
99 Somapacitan 1件: Somapacitan1件: Somapacitan 💬 1件: GHR 💬 6件: Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, Hormone signaling, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway 💬1件: 195 💬
100 Somatorelin 1件: Somatorelin1件: Somatorelin 💬 1件: GHRHR 💬 3件: Growth hormone synthesis, secretion and action, Hormone signaling, Neuroactive ligand-receptor interaction 💬1件: 13 💬
101 Somatostatin 1件: Somatostatin1件: Somatostatin 💬 5件: SSTR1,
SSTR2,
SSTR3,
SSTR4,
SSTR5 💬 		5件: Gastric acid secretion, Growth hormone synthesis, secretion and action, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬1件: 77 💬
102 Somatotropin 7件: Growth hormone; Human growth hormone; Recombinant human growth hormone; Rhgh; Somatotropin; Somatropin; Somatropina1件: Somatropin 💬 1件: GHR 💬 6件: Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, Hormone signaling, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway 💬28件: 2, 3, 13, 19, 36, 46, 65, 74, 75, 76, 77, 78, 96, 97, 107, 113, 156, 187, 191, 193, 195, 238, 246, 265, 274, 276, 299, 337 💬
103 Sonlicromanol 2件: KH176; Sonlicromanol---2件: 21, 302 💬
104 Soquelitinib 1件: Soquelitinib1件: Soquelitinib 💬 1件: ITK 💬 3件: Chemokine signaling pathway, Leukocyte transendothelial migration, T cell receptor signaling pathway 💬1件: 65 💬
105 Sorafenib 1件: Sorafenib2件: Sorafenib tosylate ,
Sorafenib 💬 		8件: BRAF,
FLT3,
FLT4,
KDR,
KIT,
PDGFRB,
RAF1,
RET 💬 		87件: Acute myeloid leukemia, Alcoholism, Alzheimer disease, Apelin signaling pathway, Apoptosis, Autophagy - animal, Axon guidance, B cell receptor signaling pathway, Bladder cancer, Breast cancer, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Choline metabolism in cancer, Chronic myeloid leukemia, Colorectal cancer, Cushing syndrome, Endometrial cancer, ErbB signaling pathway, Estrogen signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Fluid shear stress and atherosclerosis, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Hepatocellular carcinoma, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Influenza A, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Long-term depression, Long-term potentiation, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-small cell lung cancer, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Renal cell carcinoma, Salmonella infection, Serotonergic synapse, Signaling pathways regulating pluripotency of stem cells, Sphingolipid signaling pathway, T cell receptor signaling pathway, Thyroid cancer, Thyroid hormone signaling pathway, Transcriptional misregulation in cancer, Tuberculosis, VEGF signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway, mTOR signaling pathway 💬2件: 34, 86 💬
106 Soraprazan 1件: Soraprazan---1件: 301 💬
107 Sorbitol 2件: D-glucitol; Sorbitol1件: Sorbitol solution 💬 --3件: 10, 28, 97 💬
108 Sotagliflozin 1件: Sotagliflozin1件: Sotagliflozin 💬 1件: SLC5A1 💬 3件: Bile secretion, Carbohydrate digestion and absorption, Mineral absorption 💬2件: 58, 84 💬
109 Sotatercept 1件: Sotatercept1件: Sotatercept 💬 1件: ACVR2A 💬 4件: Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Signaling pathways regulating pluripotency of stem cells, TGF-beta signaling pathway 💬2件: 86, 284 💬
110 Soticlestat 1件: Soticlestat1件: Soticlestat 💬 1件: CYP46A1 💬 1件: Primary bile acid biosynthesis 💬2件: 140, 144 💬
111 Sotrastaurin 0件: 2件: Sotrastaurin ,
Sotrastaurin acetate 💬 		4件: PRKCD,
PRKCE,
PRKCH,
PRKCQ 💬 		29件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Aldosterone synthesis and secretion, Apelin signaling pathway, Autophagy - animal, C-type lectin receptor signaling pathway, Chemical carcinogenesis - reactive oxygen species, Chemokine signaling pathway, Diabetic cardiomyopathy, Estrogen signaling pathway, Fc gamma R-mediated phagocytosis, GnRH signaling pathway, Inflammatory mediator regulation of TRP channels, Insulin resistance, MicroRNAs in cancer, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Neurotrophin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Prion disease, Shigellosis, Sphingolipid signaling pathway, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬1件: 97 💬
112 Soybean 0件: ---1件: 97 💬
113 SP-101 0件: ---1件: 299 💬
114 Sparsentan 1件: Sparsentan1件: Sparsentan 💬 2件: AGTR1,
EDNRA 💬 		18件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Hormone signaling, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬3件: 66, 218, 222 💬
115 Spectinomycin 0件: 2件: Spectinomycin hydrochloride ,
Spectinomycin 💬 		--1件: 13 💬
116 Spesolimab 1件: Spesolimab1件: Spesolimab 💬 1件: IL1RL2 💬 1件: Cytokine-cytokine receptor interaction 💬5件: 37, 96, 97, 160, 269 💬
117 SPG302 1件: SPG302---1件: 2 💬
118 SPG601 1件: SPG601---1件: 206 💬
119 Spheramine 1件: Spheramine---1件: 6 💬
120 Spironolactone 1件: Spironolactone1件: Spironolactone 💬 1件: NR3C2 💬 1件: Aldosterone-regulated sodium reabsorption 💬8件: 46, 58, 67, 86, 113, 210, 218, 225 💬
121 Spirulina platensis 1件: Spirulina platensis---1件: 299 💬
122 SRP-6004 1件: SRP-6004---1件: 113 💬
123 SRP-9005 1件: SRP-9005---1件: 113 💬
124 ST-36 2件: ST 36; ST36---3件: 6, 46, 49 💬
125 Stamulumab 1件: MYO-0291件: Stamulumab 💬 1件: MSTN 💬 1件: Cytokine-cytokine receptor interaction 💬1件: 113 💬
126 Stannsoporfin 1件: TIN mesoporphyrin1件: Stannsoporfin 💬 2件: HMOX1,
HMOX2 💬 		9件: Chemical carcinogenesis - reactive oxygen species, Ferroptosis, Fluid shear stress and atherosclerosis, HIF-1 signaling pathway, Hepatocellular carcinoma, MicroRNAs in cancer, Mineral absorption, Pathways in cancer, Porphyrin metabolism 💬1件: 254 💬
127 Stanozolol 1件: Stanozolol1件: Stanozolol 💬 1件: AR 💬 4件: Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬1件: 60 💬
128 Starch, corn 2件: Corn starch; Cornstarch1件: Corn starch 💬 --4件: 49, 90, 97, 257 💬
129 Stavudine 1件: Stavudine1件: Stavudine 💬 --1件: 265 💬
130 STG-001 1件: STG-001---1件: 301 💬
131 Stiripentol 1件: Stiripentol1件: Stiripentol 💬 --2件: 140, 234 💬
132 Strimvelis 1件: Strimvelis---1件: 65 💬
133 Succimer 1件: Dmsa1件: Succimer 💬 --1件: 171 💬
134 Sucralfate 1件: Sucralfate1件: Sucralfate 💬 --1件: 98 💬
135 Sufentanil 1件: Sufentanil2件: Sufentanil citrate ,
Sufentanil 💬 		1件: OPRM1 💬 5件: Estrogen signaling pathway, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬4件: 11, 22, 70, 280 💬
136 Sugammadex 1件: Sugammadex1件: Sugammadex sodium 💬 --1件: 11 💬
137 Sulfadoxine 1件: Sulfadoxine1件: Sulfadoxine 💬 --1件: 65 💬
138 Sulfamethoxazole 2件: Sulfamethoxazole; Sulphamethoxazole1件: Sulfamethoxazole 💬 --2件: 85, 299 💬
139 Sulfanilamide 0件: 1件: Sulfanilamide 💬 --1件: 298 💬
140 Sulfasalazine 4件: Salazosulfapyridine; Salicylazosulfapyridine; Sulfasalazin; Sulfasalazine1件: Sulfasalazine 💬 --8件: 46, 49, 54, 86, 94, 107, 270, 271 💬
141 Sulfate ion 1件: Sulfate1件: Sulfuric acid 💬 --8件: 2, 3, 11, 49, 53, 64, 222, 224 💬
142 Sulforaphane 1件: Sulforaphane---2件: 6, 205 💬
143 Sulfur hexafluoride 2件: Sulfur hexafluoride; Sulphur hexafluoride1件: Sulfur hexafluoride 💬 --3件: 96, 97, 215 💬
144 Sulindac 0件: 1件: Sulindac 💬 2件: PTGS1,
PTGS2 💬 		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬1件: 206 💬
145 Sumanirole 1件: Sumanirole---1件: 6 💬
146 Sunflower oil 1件: Sunflower OIL1件: Sunflower oil 💬 --2件: 46, 299 💬
147 Sunitinib 2件: Sunitinib; Sunitinib malate2件: Sunitinib malate ,
Sunitinib 💬 		9件: CSF1R,
FLT1,
FLT3,
FLT4,
KDR,
KIT,
PDGFRA,
PDGFRB,
RET 💬 		35件: Acute myeloid leukemia, Breast cancer, Calcium signaling pathway, Central carbon metabolism in cancer, Choline metabolism in cancer, Cytokine-cytokine receptor interaction, Endocytosis, Fluid shear stress and atherosclerosis, Focal adhesion, Gap junction, Glioma, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Non-small cell lung cancer, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Rheumatoid arthritis, Thyroid cancer, Transcriptional misregulation in cancer, VEGF signaling pathway, Viral protein interaction with cytokine and cytokine receptor 💬2件: 28, 34 💬
148 Suplatast 2件: Suplatast; Suplatast tosilate1件: Suplatast tosilate 💬 --2件: 85, 226 💬
149 Suramin 1件: Suramin---1件: 331 💬
150 Susoctocog alfa 1件: Susoctocog alfa1件: Susoctocog alfa 💬 1件: F8 💬 1件: Complement and coagulation cascades 💬1件: 288 💬
151 Sutimlimab 1件: Sutimlimab1件: Sutimlimab 💬 1件: C1S 💬 5件: Complement and coagulation cascades, Coronavirus disease - COVID-19, Pertussis, Staphylococcus aureus infection, Systemic lupus erythematosus 💬1件: 61 💬
152 Suvecaltamide 1件: Suvecaltamide1件: Suvecaltamide 💬 3件: CACNA1G,
CACNA1H,
CACNA1I 💬 		8件: Aldosterone synthesis and secretion, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, GnRH secretion, MAPK signaling pathway, Type II diabetes mellitus 💬1件: 6 💬
153 Suvodirsen 1件: Suvodirsen---1件: 113 💬
154 Suvorexant 1件: Suvorexant1件: Suvorexant 💬 2件: HCRTR1,
HCRTR2 💬 		2件: Hormone signaling, Neuroactive ligand-receptor interaction 💬3件: 5, 6, 13 💬
155 SYNB1020 1件: SYNB1020---1件: 251 💬
156 SYNB1353 1件: SYNB1353---1件: 337 💬