Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank 薬物名（臨床試験情報から抽出） KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Oat 1件: Oat---1件: 46 💬
2 Obatoclax 1件: Obatoclax1件: Obatoclax mesylate 💬 1件: BCL2 💬 40件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Amyotrophic lateral sclerosis, Apoptosis, Apoptosis - multiple species, Autophagy - animal, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Colorectal cancer, Epstein-Barr virus infection, Estrogen signaling pathway, Fluid shear stress and atherosclerosis, Focal adhesion, Gastric cancer, HIF-1 signaling pathway, Hedgehog signaling pathway, Hepatitis B, Herpes simplex virus 1 infection, Human immunodeficiency virus 1 infection, JAK-STAT signaling pathway, Lipid and atherosclerosis, Measles, MicroRNAs in cancer, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Necroptosis, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Prostate cancer, Protein processing in endoplasmic reticulum, Salmonella infection, Shigellosis, Small cell lung cancer, Sphingolipid signaling pathway, Toxoplasmosis, Tuberculosis, p53 signaling pathway 💬1件: 60 💬
3 Obecabtagene autoleucel 1件: Obecabtagene autoleucel1件: Obecabtagene autoleucel 💬 1件: CD19 💬 5件: B cell receptor signaling pathway, Epstein-Barr virus infection, Hematopoietic cell lineage, PI3K-Akt signaling pathway, Primary immunodeficiency 💬2件: 13, 49 💬
4 Obefazimod 1件: Obefazimod1件: Obefazimod 💬 3件: NCBP1,
NCBP2,
NCBP2L 💬 		4件: Amyotrophic lateral sclerosis, Nucleocytoplasmic transport, Spliceosome, mRNA surveillance pathway 💬2件: 96, 97 💬
5 Obeticholic acid 1件: Obeticholic Acid1件: Obeticholic acid 💬 1件: NR1H4 💬 1件: Bile secretion 💬3件: 93, 265, 296 💬
6 Obexelimab 2件: Obexelimab; XMAB58711件: Obexelimab 💬 1件: CD19 💬 5件: B cell receptor signaling pathway, Epstein-Barr virus infection, Hematopoietic cell lineage, PI3K-Akt signaling pathway, Primary immunodeficiency 💬4件: 13, 49, 61, 300 💬
7 Obicetrapib 1件: OBICETRAPIB1件: Obicetrapib 💬 1件: CETP 💬 1件: Cholesterol metabolism 💬1件: 79 💬
8 Obinutuzumab 1件: Obinutuzumab1件: Obinutuzumab 💬 1件: MS4A1 💬 1件: Hematopoietic cell lineage 💬6件: 43, 44, 49, 63, 222, 223 💬
9 Ocrelizumab 2件: Ocrelizumab; RhuMAb 2H71件: Ocrelizumab 💬 1件: MS4A1 💬 1件: Hematopoietic cell lineage 💬4件: 11, 13, 46, 49 💬
10 Octreotide 4件: OCTREOTIDA; Octreotide; OCTREOTIDE ACETATE; OCTREOTIDE HYDROCHLORIDE5件: Octreotide ,
Octreotide acetate ,
Octreotide pamoate ,
Octreotide acetate ,
Octreotide hydrochloride 💬 		1件: SSTR2 💬 5件: Gastric acid secretion, Growth hormone synthesis, secretion and action, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬8件: 67, 75, 77, 84, 85, 89, 193, 227 💬
11 OCU400 1件: OCU400---1件: 90 💬
12 OCU410ST 1件: OCU410ST---1件: 301 💬
13 Odevixibat 1件: Odevixibat2件: Odevixibat ,
Odevixibat hydrate 💬 		1件: SLC10A2 💬 1件: Bile secretion 💬3件: 296, 297, 338 💬
14 Odiparcil 1件: Odiparcil---1件: 19 💬
15 Ofatumumab 2件: HuMax-CD20; Ofatumumab1件: Ofatumumab 💬 1件: MS4A1 💬 1件: Hematopoietic cell lineage 💬6件: 11, 13, 35, 46, 222, 223 💬
16 Olanzapine 1件: OLANZAPINE2件: Olanzapine ,
Olanzapine pamoate 💬 		11件: ADRA1A,
ADRA1B,
ADRA1D,
DRD2,
DRD3,
DRD4,
HRH1,
HTR2A,
HTR2B,
HTR2C,
HTR6 💬 		18件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Salivary secretion, Serotonergic synapse, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬2件: 2, 8 💬
17 Olaparib 1件: Olaparib1件: Olaparib 💬 2件: PARP1,
PARP2 💬 		5件: Apoptosis, Base excision repair, Diabetic cardiomyopathy, NF-kappa B signaling pathway, Necroptosis 💬2件: 86, 285 💬
18 Oleic Acid 1件: Oleic Acid1件: Oleic acid 💬 --2件: 13, 299 💬
19 Olenasufligene relduparvovec 2件: LYS-SAF302; OLENASUFLIGENE RELDUPARVOVEC---1件: 19 💬
20 Olesoxime 1件: Olesoxime1件: Olesoxime 💬 --3件: 2, 3, 13 💬
21 Oliceridine 1件: Oliceridine1件: Oliceridine 💬 3件: ARRB1,
ARRB2,
OPRM1 💬 		15件: Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Dopaminergic synapse, Endocytosis, Estrogen signaling pathway, GnRH secretion, Hedgehog signaling pathway, Hormone signaling, MAPK signaling pathway, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Relaxin signaling pathway 💬2件: 46, 70 💬
22 Olipudase alfa 1件: OLIPUDASE ALFA1件: Olipudase alfa 💬 1件: SMPD1 💬 4件: Lysosome biogenesis, Necroptosis, Sphingolipid metabolism, Sphingolipid signaling pathway 💬1件: 19 💬
23 Olive oil 1件: Olive oil1件: Olive oil 💬 --10件: 13, 34, 35, 46, 49, 53, 97, 124, 162, 271 💬
24 Olmesartan 2件: Olmesartan; Olmesartan medoxomil2件: Olmesartan medoxomil ,
Olmesartan 💬 		1件: AGTR1 💬 17件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Hormone signaling, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬2件: 57, 223 💬
25 Olokizumab 1件: Olokizumab1件: Olokizumab 💬 1件: IL6 💬 49件: AGE-RAGE signaling pathway in diabetic complications, African trypanosomiasis, Alcoholic liver disease, Alzheimer disease, Amoebiasis, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease, Coronavirus disease, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Epstein-Barr virus infection, FoxO signaling pathway, Graft-versus-host disease, HIF-1 signaling pathway, Hematopoietic cell lineage, Hepatitis B, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Lipid and atherosclerosis, Malaria, Measles, NOD-like receptor signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Rheumatoid arthritis, Salmonella infection, TNF signaling pathway, Th17 cell differentiation, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Tuberculosis, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection 💬2件: 46, 96 💬
26 Olsalazine 1件: Olsalazine2件: Olsalazine sodium ,
Olsalazine 💬 		--1件: 271 💬
27 Omadacycline 1件: Omadacycline2件: Omadacycline ,
Omadacycline tosylate 💬 		--1件: 299 💬
28 Omalizumab 1件: Omalizumab1件: Omalizumab 💬 1件: FCER1A 💬 4件: Asthma, Fc epsilon RI signaling pathway, Phospholipase D signaling pathway, Sphingolipid signaling pathway 💬7件: 46, 53, 65, 98, 162, 226, 299 💬
29 Omaveloxolone 1件: Omaveloxolone1件: Omaveloxolone 💬 1件: NFE2L2 💬 7件: Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Lipid and atherosclerosis, Parkinson disease, Pathways in cancer, Protein processing in endoplasmic reticulum 💬1件: 18 💬
30 Omega-3 fatty acids 3件: Omega 3 fatty acids; Omega-3; Omega-3 fatty acids---4件: 13, 49, 79, 223 💬
31 Omeprazole 3件: Omeprazol; Omeprazole; OMEPRAZOLE MAGNESIUM3件: Omeprazole ,
Omeprazole sodium ,
Omeprazole magnesium 💬 		2件: ATP4A,
ATP4B 💬 		3件: Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation 💬18件: 6, 8, 13, 21, 46, 51, 67, 85, 90, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
32 Omidubicel 1件: Omidubicel1件: Omidubicel 💬 1件: CD34 💬 2件: Cell adhesion molecule (CAM) interaction, Hematopoietic cell lineage 💬1件: 60 💬
33 Omigapil 1件: Omigapil---1件: 113 💬
34 OMS906 1件: OMS906---2件: 62, 223 💬
35 Onasemnogene abeparvovec 3件: ONASEMNOGENE ABEPARVOVEC; Onasemnogene Abeparvovec-brve; Onasemnogene Abeparvovec-xioi1件: Onasemnogene abeparvovec 💬 --1件: 3 💬
36 Ondansetron 2件: Ondansetron; Ondansetron hydrochloride dihydrate2件: Ondansetron ,
Ondansetron hydrochloride hydrate 💬 		5件: HTR3A,
HTR3B,
HTR3C,
HTR3D,
HTR3E 💬 		3件: Neuroactive ligand signaling, Serotonergic synapse, Taste transduction 💬5件: 6, 97, 98, 107, 231 💬
37 Ongericimab 1件: Ongericimab---1件: 79 💬
38 Ontamalimab 1件: Ontamalimab---2件: 96, 97 💬
39 Opicapone 1件: OPICAPONE1件: Opicapone 💬 1件: COMT 💬 3件: Dopaminergic synapse, Steroid hormone biosynthesis, Tyrosine metabolism 💬1件: 6 💬
40 Opicinumab 1件: Opicinumab1件: Opicinumab 💬 --1件: 13 💬
41 ORE-1001 0件: ---1件: 97 💬
42 Orelabrutinib 1件: Orelabrutinib1件: Orelabrutinib 💬 1件: BTK 💬 7件: B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬5件: 13, 49, 53, 61, 63 💬
43 Orilanolimab 1件: ORILANOLIMAB1件: Orilanolimab 💬 --1件: 61 💬
44 ORM-12741 1件: ORM-12741---1件: 51 💬
45 Ornithine 1件: Ornithine2件: Ornithine ,
Ornithine aspartate 💬 		--3件: 96, 245, 251 💬
46 Orvepitant 1件: ORVEPITANT1件: Orvepitant 💬 1件: TACR1 💬 3件: Calcium signaling pathway, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬1件: 85 💬
47 Oseltamivir 1件: Oseltamivir2件: Oseltamivir phosphate ,
Oseltamivir 💬 		--3件: 63, 97, 299 💬
48 Osilodrostat 1件: OSILODROSTAT2件: Osilodrostat ,
Osilodrostat phosphate 💬 		1件: CYP11B2 💬 2件: Aldosterone synthesis and secretion, Steroid hormone biosynthesis 💬1件: 75 💬
49 OSU-6162 0件: ---2件: 6, 8 💬
50 Otelixizumab 1件: Otelixizumab1件: Otelixizumab 💬 3件: CD3D,
CD3E,
CD3G 💬 		11件: Chagas disease, Epstein-Barr virus infection, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Human immunodeficiency virus 1 infection, Measles, PD-L1 expression and PD-1 checkpoint pathway in cancer, Primary immunodeficiency, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation 💬1件: 46 💬
51 Otilimab 1件: OTILIMAB1件: Otilimab 💬 1件: CSF2 💬 16件: Acute myeloid leukemia, Amoebiasis, Coronavirus disease, Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, IL-17 signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Natural killer cell mediated cytotoxicity, Rheumatoid arthritis, Shigellosis, T cell receptor signaling pathway, TNF signaling pathway, Transcriptional misregulation in cancer 💬1件: 46 💬
52 OTL-203 1件: OTL-203---1件: 19 💬
53 Oxabact 2件: Oxabact; Oxalobacter formigenes---1件: 234 💬
54 Oxaloacetic acid 1件: Oxaloacetic Acid---1件: 2 💬
55 Oxandrolone 1件: Oxandrolone1件: Oxandrolone 💬 1件: AR 💬 4件: Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬2件: 211, 285 💬
56 Oxatomide 1件: Oxatomide1件: Oxatomide 💬 1件: ALOX5 💬 6件: Arachidonic acid metabolism, Efferocytosis, Fc epsilon RI signaling pathway, Ovarian steroidogenesis, Serotonergic synapse, Toxoplasmosis 💬1件: 113 💬
57 Oxcarbazepine 1件: Oxcarbazepine1件: Oxcarbazepine 💬 6件: SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN8A,
SCN9A 💬 		5件: Adrenergic signaling in cardiomyocytes, Cadherin signaling, Dopaminergic synapse, IgSF CAM signaling, Taste transduction 💬1件: 13 💬
58 Oxiconazole 1件: Oxiconazole2件: Oxiconazole nitrate ,
Oxiconazole 💬 		--1件: 160 💬
59 Oxitriptan 2件: 5-HTP; OXITRIPTAN1件: Oxitriptan 💬 --1件: 97 💬
60 Oxybuprocaine 1件: Oxybuprocaine2件: Benoxinate hydrochloride ,
Oxybuprocaine 💬 		6件: SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN8A,
SCN9A 💬 		5件: Adrenergic signaling in cardiomyocytes, Cadherin signaling, Dopaminergic synapse, IgSF CAM signaling, Taste transduction 💬1件: 6 💬
61 Oxybutynin 1件: Oxybutynin2件: Oxybutynin ,
Oxybutynin chloride 💬 		5件: CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬 		14件: Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬3件: 6, 13, 53 💬
62 Oxycodone 2件: Oxycodone; OXYCODONE HYDROCHLORIDE3件: Oxycodone hydrochloride ,
Oxycodone terephthalate ,
Oxycodone 💬 		3件: OPRD1,
OPRK1,
OPRM1 💬 		7件: Estrogen signaling pathway, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬7件: 6, 13, 46, 70, 226, 231, 298 💬
63 Oxygen 1件: Oxygen1件: Oxygen 💬 --30件: 6, 13, 15, 19, 22, 36, 46, 49, 70, 71, 85, 86, 88, 90, 96, 97, 129, 149, 168, 193, 211, 226, 230, 235, 269, 271, 294, 298, 299, 330 💬
64 Oxymatrine 1件: Oxymatrine---1件: 37 💬
65 Oxytocin 1件: Oxytocin1件: Oxytocin 💬 1件: OXTR 💬 5件: Calcium signaling pathway, Hormone signaling, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, cAMP signaling pathway 💬8件: 6, 70, 72, 127, 168, 193, 206, 226 💬
66 Oyster 1件: Oyster---1件: 84 💬
67 Ozanezumab 1件: Ozanezumab1件: Ozanezumab 💬 1件: RTN4 💬 1件: Alzheimer disease 💬1件: 2 💬
68 Ozanimod 2件: OZANIMOD; Ozanimod hydrochloride2件: Ozanimod hydrochloride ,
Ozanimod 💬 		5件: S1PR1,
S1PR2,
S1PR3,
S1PR4,
S1PR5 💬 		4件: Efferocytosis, FoxO signaling pathway, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway 💬3件: 13, 96, 97 💬
69 Ozone 1件: Ozone---5件: 49, 51, 70, 71, 226 💬
70 Ozoralizumab 1件: Ozoralizumab1件: Ozoralizumab 💬 1件: TNF 💬 66件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬1件: 46 💬