Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank 薬物名（臨床試験情報から抽出） KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Ianalumab 1件: Ianalumab1件: Ianalumab 💬 1件: TNFRSF13C 💬 5件: Cytokine-cytokine receptor interaction, Human T-cell leukemia virus 1 infection, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Primary immunodeficiency 💬8件: 35, 46, 49, 51, 53, 61, 63, 95 💬
2 Ibandronate 2件: Ibandronate; Ibandronic acid2件: Ibandronate sodium ,
Ibandronic acid 💬 		1件: FDPS 💬 3件: Human T-cell leukemia virus 1 infection, Influenza A, Terpenoid backbone biosynthesis 💬3件: 46, 49, 274 💬
3 Ibrutinib 1件: Ibrutinib1件: Ibrutinib 💬 1件: BTK 💬 7件: B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬3件: 28, 60, 61 💬
4 Ibudilast 1件: Ibudilast1件: Ibudilast 💬 8件: CYSLTR1,
PDE3A,
PDE3B,
PDE4,
PDE4,
PDE4,
PDE4,
PTGIR 💬 		15件: Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Parathyroid hormone synthesis, secretion and action, Platelet activation, Progesterone-mediated oocyte maturation, Purine metabolism, Regulation of lipolysis in adipocytes, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬2件: 2, 13 💬
5 Ibuprofen 1件: Ibuprofen5件: Ibuprofen ,
Ibuprofen aluminum ,
Ibuprofen lysine ,
Ibuprofen sodium ,
Ibuprofen sodium 💬 		2件: PTGS1,
PTGS2 💬 		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬6件: 13, 46, 65, 113, 271, 299 💬
6 Icatibant 2件: Icatibant; Icatibant acetate1件: Icatibant acetate 💬 1件: BDKRB2 💬 10件: Calcium signaling pathway, Chagas disease, Complement and coagulation cascades, Endocrine and other factor-regulated calcium reabsorption, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Pathways in cancer, Regulation of actin cytoskeleton, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬1件: 65 💬
7 Icerguastat 1件: Icerguastat---1件: 2 💬
8 Icosapent 1件: Eicosapentaenoic acid1件: Icosapent 💬 --9件: 46, 48, 49, 96, 97, 113, 296, 297, 338 💬
9 Icosapent ethyl 1件: Ethyl-EPA1件: Icosapent ethyl 💬 --1件: 8 💬
10 Icotinib 1件: Icotinib1件: Icotinib 💬 1件: EGFR 💬 47件: Adherens junction, Bladder cancer, Breast cancer, Calcium signaling pathway, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Coronavirus disease - COVID-19, Cushing syndrome, Endocytosis, Endometrial cancer, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH signaling pathway, HIF-1 signaling pathway, Hepatitis C, Hepatocellular carcinoma, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, Non-small cell lung cancer, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Virion - Hepatitis viruses 💬1件: 34 💬
11 ICX-RHY 0件: ---1件: 36 💬
12 Idebenone 1件: Idebenone1件: Idebenone 💬 --7件: 6, 8, 13, 18, 21, 113, 302 💬
13 Idecabtagene vicleucel 1件: Idecabtagene vicleucel1件: Idecabtagene vicleucel 💬 1件: TNFRSF17 💬 2件: Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production 💬1件: 28 💬
14 Idursulfase 2件: Idursulfasa; Idursulfase1件: Idursulfase 💬 1件: IDS 💬 2件: Glycosaminoglycan degradation, Lysosome 💬1件: 19 💬
15 Idursulfase beta 2件: Hunterase; Idursulfase beta1件: Idursulfase beta 💬 1件: IDS 💬 2件: Glycosaminoglycan degradation, Lysosome 💬1件: 19 💬
16 Ifenprodil 1件: Ifenprodil2件: Ifenprodil tartrate ,
Ifenprodil 💬 		3件: ADRA1A,
ADRA1B,
ADRA1D 💬 		9件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬1件: 13 💬
17 Ifetroban 2件: Ifetroban; Ifetroban sodium2件: Ifetroban ,
Ifetroban sodium 💬 		1件: TBXA2R 💬 3件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Platelet activation 💬2件: 85, 113 💬
18 Ifosfamide 1件: Ifosfamide1件: Ifosfamide 💬 --1件: 34 💬
19 Iguratimod 1件: Iguratimod1件: Iguratimod 💬 1件: NFKB1 💬 75件: AGE-RAGE signaling pathway in diabetic complications, Acute myeloid leukemia, Adipocytokine signaling pathway, Alcoholic liver disease, Alzheimer disease, Amoebiasis, Apoptosis, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Chronic myeloid leukemia, Cocaine addiction, Coronavirus disease - COVID-19, Cytosolic DNA-sensing pathway, Diabetic cardiomyopathy, Epithelial cell signaling in Helicobacter pylori infection, Epstein-Barr virus infection, Fluid shear stress and atherosclerosis, HIF-1 signaling pathway, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, Longevity regulating pathway, MAPK signaling pathway, Measles, MicroRNAs in cancer, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-alcoholic fatty liver disease, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Pertussis, Prolactin signaling pathway, Prostate cancer, RIG-I-like receptor signaling pathway, Ras signaling pathway, Relaxin signaling pathway, Salmonella infection, Shigellosis, Small cell lung cancer, Sphingolipid signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Tuberculosis, Viral carcinogenesis, Yersinia infection, cAMP signaling pathway 💬6件: 46, 49, 51, 53, 271, 300 💬
20 IKT-001Pro 1件: IKT-001PRO---1件: 86 💬
21 Iloperidone 1件: Iloperidone1件: Iloperidone 💬 4件: DRD2,
HTR2,
HTR2,
HTR2 💬 		13件: Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, cAMP signaling pathway 💬1件: 6 💬
22 Iloprost 1件: Iloprost2件: Iloprost ,
Iloprost tromethamine 💬 		1件: PTGIR 💬 3件: Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬4件: 51, 84, 85, 86 💬
23 Imatinib 2件: Imatinib; Imatinib mesylate2件: Imatinib mesylate ,
Imatinib 💬 		3件: ABL1,
KIT,
PDGFRA 💬 		31件: Acute myeloid leukemia, Axon guidance, Breast cancer, Calcium signaling pathway, Cell cycle, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Choline metabolism in cancer, Chronic myeloid leukemia, Endocytosis, ErbB signaling pathway, Focal adhesion, Gap junction, Glioma, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Viral myocarditis 💬12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
24 IMCY-0141 1件: IMCY-0141---1件: 13 💬
25 Imidacloprid 0件: ---5件: 19, 20, 125, 234, 326 💬
26 Imidapril 1件: Imidapril2件: Imidapril hydrochloride ,
Imidapril 💬 		1件: ACE 💬 6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬1件: 67 💬
27 Imiglucerase 2件: Imiglucerasa; Imiglucerase2件: Alglucerase ,
Imiglucerase 💬 		1件: GBA 💬 4件: Cornified envelope formation, Lysosome, Other glycan degradation, Sphingolipid metabolism 💬1件: 19 💬
28 Imipenem 0件: 2件: Imipenem ,
Imipenem 💬 		--2件: 60, 299 💬
29 Imiquimod 0件: 1件: Imiquimod 💬 1件: TLR7 💬 5件: Coronavirus disease - COVID-19, Influenza A, Measles, Neutrophil extracellular trap formation, Toll-like receptor signaling pathway 💬2件: 34, 51 💬
30 Imlifidase 3件: HMED-ides; Ides; Imlifidase1件: Imlifidase 💬 --5件: 43, 44, 64, 113, 221 💬
31 Implitapide 1件: Implitapide---1件: 79 💬
32 Imsidolimab 1件: Imsidolimab1件: Imsidolimab 💬 1件: IL1RL2 💬 1件: Cytokine-cytokine receptor interaction 💬1件: 37 💬
33 Imvotamab 1件: Imvotamab1件: Imvotamab 💬 2件: CD3E,
MS4A1 💬 		11件: Chagas disease, Epstein-Barr virus infection, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Human immunodeficiency virus 1 infection, Measles, PD-L1 expression and PD-1 checkpoint pathway in cancer, Primary immunodeficiency, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation 💬2件: 46, 49 💬
34 Inaticabtagene Autoleucel 0件: ---1件: 49 💬
35 INBRX-101 0件: ---1件: 231 💬
36 Inclisiran 3件: ALN-pcssc; Inclisiran; Inclisiran sodium2件: Inclisiran ,
Inclisiran sodium 💬 		1件: PCSK9 💬 1件: Cholesterol metabolism 💬1件: 79 💬
37 Indapamide 0件: 1件: Indapamide 💬 1件: SLC12A3 💬 1件: Parathyroid hormone synthesis, secretion and action 💬1件: 13 💬
38 Indian frankincense 0件: ---1件: 13 💬
39 Indigo 1件: Indigo---3件: 97, 289, 300 💬
40 Indinavir 1件: Indinavir3件: Indinavir sulfate ,
Indinavir sulfate ethanolate ,
Indinavir 💬 		--1件: 265 💬
41 Indium 0件: ---3件: 28, 84, 299 💬
42 Indocyanine green 1件: Indocyanine green1件: Indocyanine green 💬 --8件: 22, 46, 51, 96, 235, 278, 291, 296 💬
43 Indomethacin 2件: Indometacin; Indomethacin2件: Indomethacin ,
Indomethacin sodium 💬 		2件: PTGS1,
PTGS2 💬 		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬3件: 225, 271, 298 💬
44 Indopan 0件: ---5件: 2, 8, 19, 46, 97 💬
45 Inebilizumab 1件: Inebilizumab1件: Inebilizumab 💬 1件: CD19 💬 5件: B cell receptor signaling pathway, Epstein-Barr virus infection, Hematopoietic cell lineage, PI3K-Akt signaling pathway, Primary immunodeficiency 💬6件: 11, 13, 46, 49, 51, 300 💬
46 Infigratinib 2件: Infigratinib; Infigratinib phosphate2件: Infigratinib ,
Infigratinib phosphate 💬 		3件: FGFR1,
FGFR2,
FGFR3 💬 		20件: Adherens junction, Bladder cancer, Breast cancer, Calcium signaling pathway, Central carbon metabolism in cancer, Endocytosis, Gastric cancer, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, PI3K-Akt signaling pathway, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Signaling pathways regulating pluripotency of stem cells, Thermogenesis 💬1件: 276 💬
47 Infliximab 1件: Infliximab1件: Infliximab 💬 1件: TNF 💬 66件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 95, 96, 97, 98, 107, 164, 269, 270, 271 💬
48 Inosine 1件: Inosine1件: Inosine 💬 --5件: 2, 6, 13, 85, 122 💬
49 Inositol 1件: Inositol1件: Inositol 💬 --2件: 96, 97 💬
50 Inotersen 1件: Inotersen2件: Inotersen ,
Inotersen sodium 💬 		1件: TTR 💬 1件: Thyroid hormone synthesis 💬1件: 28 💬
51 INS018_055 1件: INS018_055---1件: 85 💬
52 Insulin detemir 0件: 1件: Insulin detemir 💬 1件: INSR 💬 23件: AMPK signaling pathway, Adherens junction, Aldosterone-regulated sodium reabsorption, Alzheimer disease, Diabetic cardiomyopathy, FoxO signaling pathway, HIF-1 signaling pathway, Hormone signaling, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, MAPK signaling pathway, Non-alcoholic fatty liver disease, Ovarian steroidogenesis, PI3K-Akt signaling pathway, Phospholipase D signaling pathway, Rap1 signaling pathway, Ras signaling pathway, Regulation of lipolysis in adipocytes, Type II diabetes mellitus, cGMP-PKG signaling pathway, mTOR signaling pathway 💬1件: 299 💬
53 Insulin glargine 1件: Insulin glargine1件: Insulin glargine 💬 1件: INSR 💬 23件: AMPK signaling pathway, Adherens junction, Aldosterone-regulated sodium reabsorption, Alzheimer disease, Diabetic cardiomyopathy, FoxO signaling pathway, HIF-1 signaling pathway, Hormone signaling, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, MAPK signaling pathway, Non-alcoholic fatty liver disease, Ovarian steroidogenesis, PI3K-Akt signaling pathway, Phospholipase D signaling pathway, Rap1 signaling pathway, Ras signaling pathway, Regulation of lipolysis in adipocytes, Type II diabetes mellitus, cGMP-PKG signaling pathway, mTOR signaling pathway 💬1件: 299 💬
54 Insulin human 1件: Human insulin1件: Insulin human 💬 1件: INSR 💬 23件: AMPK signaling pathway, Adherens junction, Aldosterone-regulated sodium reabsorption, Alzheimer disease, Diabetic cardiomyopathy, FoxO signaling pathway, HIF-1 signaling pathway, Hormone signaling, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, MAPK signaling pathway, Non-alcoholic fatty liver disease, Ovarian steroidogenesis, PI3K-Akt signaling pathway, Phospholipase D signaling pathway, Rap1 signaling pathway, Ras signaling pathway, Regulation of lipolysis in adipocytes, Type II diabetes mellitus, cGMP-PKG signaling pathway, mTOR signaling pathway 💬1件: 156 💬
55 Insulin lispro 1件: Insulin lispro1件: Insulin lispro 💬 1件: INSR 💬 23件: AMPK signaling pathway, Adherens junction, Aldosterone-regulated sodium reabsorption, Alzheimer disease, Diabetic cardiomyopathy, FoxO signaling pathway, HIF-1 signaling pathway, Hormone signaling, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, MAPK signaling pathway, Non-alcoholic fatty liver disease, Ovarian steroidogenesis, PI3K-Akt signaling pathway, Phospholipase D signaling pathway, Rap1 signaling pathway, Ras signaling pathway, Regulation of lipolysis in adipocytes, Type II diabetes mellitus, cGMP-PKG signaling pathway, mTOR signaling pathway 💬1件: 53 💬
56 Interferon alfa 0件: 1件: Interferon alfa 💬 2件: IFNAR1,
IFNAR2 💬 		18件: Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Toll-like receptor signaling pathway 💬2件: 25, 56 💬
57 Interferon alfa-2a 2件: Interferon ALFA-2A; Interferon alpha-2A1件: Interferon alfa-2a 💬 2件: IFNAR1,
IFNAR2 💬 		18件: Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Toll-like receptor signaling pathway 💬1件: 56 💬
58 Interferon alfa-2b 1件: Interferon ALFA-2B1件: Interferon alfa-2b 💬 2件: IFNAR1,
IFNAR2 💬 		18件: Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Toll-like receptor signaling pathway 💬1件: 25 💬
59 Interferon beta-1a 4件: Interferon beta 1-A; Interferon beta 1A; Interferon BETA-1A; Interferon-BETA-1A1件: Interferon beta-1a 💬 2件: IFNAR1,
IFNAR2 💬 		18件: Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Toll-like receptor signaling pathway 💬3件: 13, 96, 97 💬
60 Interferon beta-1b 3件: Interferon beta 1B; Interferon BETA-1B; Interferon-BETA-1B1件: Interferon beta-1b 💬 2件: IFNAR1,
IFNAR2 💬 		18件: Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Toll-like receptor signaling pathway 💬1件: 13 💬
61 Interferon Gamma 1件: Interferon gamma---8件: 18, 65, 85, 96, 228, 299, 301, 326 💬
62 Interferon gamma-1b 1件: Interferon gamma-1B1件: Interferon gamma-1b 💬 2件: IFNGR1,
IFNGR2 💬 		18件: Chagas disease, Cytokine-cytokine receptor interaction, HIF-1 signaling pathway, Herpes simplex virus 1 infection, Inflammatory bowel disease, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways in cancer, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis 💬7件: 18, 65, 85, 228, 299, 301, 326 💬
63 Inulin 1件: Inulin1件: Inulin 💬 --3件: 6, 97, 299 💬
64 INZ-701 1件: INZ-701---1件: 166 💬
65 Iodide I-123 1件: I-123---2件: 2, 6 💬
66 Iodine 1件: Iodine1件: Iodine 💬 --3件: 28, 46, 96 💬
67 Ioflupane I-123 2件: Ioflupane; Ioflupane I 1231件: Ioflupane I 123 💬 1件: SLC6A3 💬 8件: Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Neuroactive ligand signaling, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬1件: 6 💬
68 Iohexol 1件: Iohexol1件: Iohexol 💬 --2件: 19, 67 💬
69 ION283 1件: ION283---1件: 309 💬
70 ION356 1件: ION356---1件: 139 💬
71 ION582 1件: ION582---1件: 201 💬
72 Ipilimumab 1件: Ipilimumab1件: Ipilimumab 💬 1件: CTLA4 💬 4件: Autoimmune thyroid disease, Cell adhesion molecules, Rheumatoid arthritis, T cell receptor signaling pathway 💬1件: 159 💬
73 Ipratropium 1件: Ipratropium---1件: 6 💬
74 Iproniazid 1件: Iproniazid2件: Iproniazid ,
Iproniazid phosphate 💬 		2件: MAO,
MAO 💬 		13件: Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬1件: 6 💬
75 Iptacopan 1件: Iptacopan2件: Iptacopan ,
Iptacopan hydrochloride 💬 		1件: CFB 💬 3件: Complement and coagulation cascades, Coronavirus disease - COVID-19, Staphylococcus aureus infection 💬6件: 11, 61, 62, 66, 109, 222 💬
76 Irbesartan 1件: Irbesartan1件: Irbesartan 💬 1件: AGTR1 💬 17件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Hormone signaling, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬4件: 66, 167, 168, 222 💬
77 Iron 1件: Iron1件: Ferrous fumarate 💬 --6件: 18, 60, 96, 97, 238, 284 💬
78 Iron Dextran 1件: Iron dextran1件: Iron dextran 💬 --2件: 62, 97 💬
79 Iron isomaltoside 1000 2件: Iron isomaltoside 1000; Monofer---1件: 97 💬
80 Iron sucrose 1件: Iron sucrose1件: Iron sucrose 💬 --3件: 62, 96, 97 💬
81 Isaralgagene civaparvovec 1件: Isaralgagene civaparvovec---1件: 19 💬
82 Isatuximab 1件: Isatuximab1件: Isatuximab 💬 1件: CD38 💬 6件: Calcium signaling pathway, Hematopoietic cell lineage, Nicotinate and nicotinamide metabolism, Oxytocin signaling pathway, Pancreatic secretion, Salivary secretion 💬3件: 28, 61, 283 💬
83 Iscalimab 1件: Iscalimab1件: Iscalimab 💬 1件: TNFRSF5 💬 17件: Allograft rejection, Asthma, Autoimmune thyroid disease, Cell adhesion molecules, Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Human T-cell leukemia virus 1 infection, Intestinal immune network for IgA production, Lipid and atherosclerosis, Malaria, NF-kappa B signaling pathway, Primary immunodeficiency, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Viral myocarditis 💬2件: 49, 53 💬
84 ISIS 104838 1件: Isis 104838---1件: 46 💬
85 Isoflurane 1件: Isoflurane1件: Isoflurane 💬 --1件: 6 💬
86 Isoleucine 1件: Isoleucine1件: Isoleucine 💬 --1件: 244 💬
87 Isoniazid 1件: Isoniazid1件: Isoniazid 💬 --3件: 49, 65, 254 💬
88 Isosorbide 0件: 1件: Isosorbide 💬 --1件: 113 💬
89 Isosorbide dinitrate 0件: 1件: Isosorbide dinitrate 💬 --1件: 113 💬
90 Isotretinoin 1件: Isotretinoin1件: Isotretinoin 💬 2件: RARA,
RARB 💬 		8件: Acute myeloid leukemia, Estrogen signaling pathway, Gastric cancer, Non-small cell lung cancer, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Transcriptional misregulation in cancer 💬4件: 36, 39, 159, 160 💬
91 Isoxaflutole 0件: ---5件: 6, 13, 18, 121, 299 💬
92 Isoxsuprine 1件: Isoxsuprine hydrochloride2件: Isoxsuprine hydrochloride ,
Isoxsuprine 💬 		1件: ADRB2 💬 11件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 13 💬
93 Isradipine 1件: Isradipine1件: Isradipine 💬 4件: CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬 		37件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 6 💬
94 Istradefylline 1件: Istradefylline1件: Istradefylline 💬 1件: ADORA2A 💬 8件: Alcoholism, Calcium signaling pathway, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway 💬1件: 6 💬
95 Itacitinib 2件: Itacitinib; Itacitinib adipate2件: Itacitinib ,
Itacitinib adipate 💬 		1件: JAK1 💬 27件: Coronavirus disease - COVID-19, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬4件: 46, 51, 97, 228 💬
96 Itepekimab 1件: Itepekimab1件: Itepekimab 💬 1件: IL33 💬 4件: Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Influenza A, Necroptosis 💬1件: 299 💬
97 ITI-214 1件: ITI-214---1件: 6 💬
98 Itolizumab 1件: Itolizumab1件: Itolizumab 💬 1件: CD6 💬 1件: Cell adhesion molecules 💬2件: 49, 50 💬
99 Itraconazole 1件: Itraconazole1件: Itraconazole 💬 --8件: 2, 3, 46, 65, 96, 97, 227, 299 💬
100 Ivacaftor 1件: Ivacaftor1件: Ivacaftor 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬2件: 299, 340 💬
101 Ixazomib 2件: Ixazomib; Ixazomib citrate2件: Ixazomib ,
Ixazomib citrate 💬 		1件: PSMB5 💬 8件: Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Prion disease, Proteasome, Spinocerebellar ataxia 💬4件: 13, 16, 28, 51 💬
102 Ixekizumab 1件: Ixekizumab1件: Ixekizumab 💬 1件: IL17A 💬 6件: Alcoholic liver disease, Cytokine-cytokine receptor interaction, IL-17 signaling pathway, Inflammatory bowel disease, Rheumatoid arthritis, Th17 cell differentiation 💬8件: 36, 37, 46, 107, 160, 162, 269, 271 💬