Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank 薬物名（臨床試験情報から抽出） KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Acetate 1件: Acetate---52件: 1, 2, 6, 10, 11, 13, 22, 35, 40, 46, 49, 51, 60, 63, 64, 65, 66, 67, 70, 71, 73, 75, 76, 77, 78, 79, 81, 83, 85, 86, 88, 89, 90, 96, 97, 113, 145, 156, 158, 162, 171, 206, 222, 223, 224, 225, 227, 235, 251, 265, 298, 299 💬
2 Blarcamesine 2件: ANAVEX2-73; Blarcamesine2件: Blarcamesine ,
Blarcamesine hydrochloride 💬 		6件: CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5,
SIGMAR1 💬 		15件: Alzheimer disease, Amyotrophic lateral sclerosis, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬1件: 156 💬
3 Butyric Acid 3件: Butyrate; Butyric Acid; Sodium butyrate1件: Sodium butyrate 💬 --3件: 46, 156, 222 💬
4 Calcium 1件: Calcium---39件: 2, 3, 6, 13, 15, 19, 46, 48, 49, 51, 53, 56, 62, 67, 68, 71, 74, 75, 79, 84, 90, 93, 94, 95, 96, 97, 156, 186, 214, 215, 222, 224, 235, 256, 265, 271, 274, 298, 299 💬
5 Cannabidiol 1件: Cannabidiol1件: Cannabidiol 💬 2件: CNR1,
CNR2 💬 		4件: Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬20件: 6, 8, 13, 19, 36, 46, 51, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬
6 Creatine 3件: Acetic acid; Creatine; Creatine monohydrate---18件: 1, 2, 3, 5, 6, 8, 13, 15, 21, 46, 49, 50, 97, 113, 156, 201, 256, 337 💬
7 Desipramine 1件: Desipramine2件: Desipramine hydrochloride ,
Desipramine 💬 		2件: SLC6A2,
SLC6A4 💬 		3件: Neuroactive ligand signaling, Serotonergic synapse, Synaptic vesicle cycle 💬2件: 121, 156 💬
8 Dextromethorphan 2件: Dextromethorphan; Dextromethorphan hydrobromide3件: Dextromethorphan hydrobromide ,
Dextromethorphan ,
Dextromethorphan polistirex 💬 		6件: GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬 		21件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬10件: 2, 6, 8, 13, 21, 46, 85, 96, 97, 156 💬
9 Donepezil 2件: Donepezil; Donepezil hydrochloride2件: Donepezil hydrochloride ,
Donepezil 💬 		1件: ACHE 💬 3件: Cholinergic synapse, Glycerophospholipid metabolism, Neuroactive ligand signaling 💬8件: 5, 6, 13, 46, 124, 127, 156, 206 💬
10 Esketamine 3件: Esketamine; Esketamine hydrochloride; Ketamine2件: Esketamine ,
Esketamine hydrochloride 💬 		5件: GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬 		21件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬7件: 2, 4, 6, 70, 96, 97, 156 💬
11 Fenfluramine 2件: Fenfluramine; FENFLURAMINE HYDROCHLORIDE2件: Fenfluramine hydrochloride ,
Fenfluramine 💬 		5件: HTR1D,
HTR2A,
HTR2C,
SIGMAR1,
SLC6A4 💬 		11件: Amyotrophic lateral sclerosis, Calcium signaling pathway, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Pathways of neurodegeneration - multiple diseases, Serotonergic synapse, Synaptic vesicle cycle, Taste transduction, cAMP signaling pathway 💬6件: 140, 143, 144, 145, 149, 156 💬
12 Fingolimod 2件: FINGOLIMOD; FINGOLIMOD HYDROCHLORIDE3件: Fingolimod hydrochloride ,
Fingolimod ,
Fingolimod lauryl sulfate 💬 		1件: S1PR1 💬 4件: Efferocytosis, FoxO signaling pathway, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway 💬3件: 13, 14, 156 💬
13 Glatiramer 2件: Glatiramer; Glatiramer acetate1件: Glatiramer acetate 💬 20件: HLA-A,
HLA-B,
HLA-C,
HLA-DMA,
HLA-DMB,
HLA-DOA,
HLA-DOB,
HLA-DPA1,
HLA-DPB1,
HLA-DQA1,
HLA-DQA2,
HLA-DQB1,
HLA-DRA,
HLA-DRB1,
HLA-DRB3,
HLA-DRB4,
HLA-DRB5,
HLA-E,
HLA-F,
HLA-G 💬 		32件: Allograft rejection, Antigen processing and presentation, Asthma, Autoimmune thyroid disease, Cell adhesion molecule (CAM) interaction, Cellular senescence, Endocytosis, Epstein-Barr virus infection, Graft-versus-host disease, Hematopoietic cell lineage, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Inflammatory bowel disease, Influenza A, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Natural killer cell mediated cytotoxicity, Phagocytosis, Rheumatoid arthritis, Staphylococcus aureus infection, Systemic lupus erythematosus, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Viral carcinogenesis, Viral myocarditis 💬4件: 2, 13, 96, 156 💬
14 Inulin 1件: Inulin1件: Inulin 💬 --5件: 6, 96, 97, 156, 299 💬
15 Ketamine 2件: Ketamine; Ketamine hydrochloride2件: Ketamine hydrochloride ,
Ketamine 💬 		5件: GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬 		21件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬6件: 6, 13, 70, 113, 156, 215 💬
16 Lactobacillus plantarum 1件: Lactobacillus plantarum---3件: 6, 97, 156 💬
17 Lamivudine 1件: Lamivudine1件: Lamivudine 💬 --10件: 2, 26, 42, 46, 49, 135, 156, 223, 265, 325 💬
18 Lovastatin 1件: LOVASTATIN1件: Lovastatin 💬 1件: HMGCR 💬 3件: AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬11件: 6, 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬
19 Mirtazapine 1件: Mirtazapine1件: Mirtazapine 💬 11件: ADRA2A,
ADRA2B,
ADRA2C,
HTR2A,
HTR2B,
HTR2C,
HTR3A,
HTR3B,
HTR3C,
HTR3D,
HTR3E 💬 		9件: Calcium signaling pathway, Gap junction, Hormone signaling, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Serotonergic synapse, Taste transduction, cGMP-PKG signaling pathway 💬4件: 6, 85, 97, 156 💬
20 NGN-401 1件: NGN-401---1件: 156 💬
21 Risperidone 1件: Risperidone1件: Risperidone 💬 2件: DRD2,
HTR2A 💬 		13件: Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, cAMP signaling pathway 💬6件: 8, 74, 156, 179, 187, 206 💬
22 Sarizotan 2件: SARIZOTAN; Sarizotan Hydrochloride1件: Sarizotan hydrochloride 💬 2件: DRD2,
HTR1A 💬 		12件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, Taste transduction, cAMP signaling pathway 💬2件: 6, 156 💬
23 Tocotrienol 1件: Tocotrienol---4件: 18, 21, 156, 299 💬
24 Topiramate 1件: Topiramate1件: Topiramate 💬 37件: CA2,
CA4,
CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S,
GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ,
GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN8A,
SCN9A 💬 		55件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Arrhythmogenic right ventricular cardiomyopathy, Bile secretion, Cadherin signaling, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Collecting duct acid secretion, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Gastric acid secretion, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Huntington disease, Hypertrophic cardiomyopathy, IgSF CAM signaling, Insulin secretion, Long-term depression, Long-term potentiation, MAPK signaling pathway, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Nitrogen metabolism, Oxytocin signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Prion disease, Proximal tubule bicarbonate reclamation, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Spinocerebellar ataxia, Taste transduction, Tight junction, Transcriptional misregulation in cancer, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬6件: 6, 97, 140, 144, 156, 193 💬
25 Triheptanoin 1件: Triheptanoin1件: Triheptanoin 💬 --12件: 2, 8, 65, 149, 156, 248, 256, 257, 317, 318, 324, 344 💬
26 Trofinetide 1件: Trofinetide1件: Trofinetide 💬 --1件: 156 💬
27 TSHA-102 1件: TSHA-102---1件: 156 💬
28 Vorinostat 1件: Vorinostat1件: Vorinostat 💬 11件: HDAC1,
HDAC10,
HDAC11,
HDAC2,
HDAC3,
HDAC4,
HDAC5,
HDAC6,
HDAC7,
HDAC8,
HDAC9 💬 		20件: ATP-dependent chromatin remodeling, Alcoholism, Amphetamine addiction, Amyotrophic lateral sclerosis, Apelin signaling pathway, Cell cycle, Chronic myeloid leukemia, Epstein-Barr virus infection, Human papillomavirus infection, Huntington disease, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, Notch signaling pathway, Pathways in cancer, Polycomb repressive complex, TGF-beta signaling pathway, Thyroid hormone signaling pathway, Transcriptional misregulation in cancer, Viral carcinogenesis 💬5件: 65, 75, 96, 97, 156 💬
29 Zinc oxide 1件: Zinc oxide1件: Zinc oxide 💬 --1件: 156 💬