Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank 薬物名（臨床試験情報から抽出） KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Ammonia 1件: Ammonia1件: Ammonia solution, strong 💬 --6件: 6, 17, 86, 88, 251, 296 💬
2 Ampreloxetine 1件: Ampreloxetine1件: Ampreloxetine 💬 2件: SLC6A2,
SLC6A4 💬 		3件: Neuroactive ligand signaling, Serotonergic synapse, Synaptic vesicle cycle 💬2件: 6, 17 💬
3 ATH434 1件: ATH434---1件: 17 💬
4 Atomoxetine 1件: Atomoxetine2件: Atomoxetine hydrochloride ,
Atomoxetine 💬 		1件: SLC6A2 💬 2件: Neuroactive ligand signaling, Synaptic vesicle cycle 💬4件: 6, 8, 13, 17 💬
5 Botulinum toxin type A 5件: Botulinum toxin A; BOTULINUM TOXIN TYPE A; IncobotulinumtoxinA; Onabotulinumtoxin A; OnabotulinumtoxinA4件: Botulinum toxin type A ,
OnabotulinumtoxinA ,
AbobotulinumtoxinA ,
Incobotulinumtoxin A 💬 		1件: SNAP25 💬 2件: Insulin secretion, Synaptic vesicle cycle 💬13件: 2, 5, 6, 7, 13, 15, 17, 47, 70, 113, 149, 171, 226 💬
6 BQ-123 0件: ---1件: 17 💬
7 Butylphthalide 2件: 3-N-butylphthalide; Butylphthalide---4件: 2, 6, 17, 22 💬
8 Captopril 1件: Captopril1件: Captopril 💬 1件: ACE 💬 6件: Chagas disease, Coronavirus disease, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬3件: 17, 57, 86 💬
9 Carbidopa 1件: Carbidopa1件: Carbidopa 💬 1件: DDC 💬 8件: Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬7件: 6, 13, 17, 90, 140, 164, 201 💬
10 Domperidone 1件: Domperidone2件: Domperidone ,
Domperidone maleate 💬 		1件: DRD2 💬 10件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬5件: 6, 13, 17, 51, 230 💬
11 Dopamine 1件: Dopamine2件: Dopamine hydrochloride ,
Dopamine 💬 		5件: DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬 		13件: Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬5件: 6, 7, 17, 74, 77 💬
12 Droxidopa 2件: Droxidopa; L-DOPS1件: Droxidopa 💬 9件: ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬 		16件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬5件: 5, 6, 17, 169, 170 💬
13 Emeramide 1件: Emeramide---2件: 5, 17 💬
14 Entacapone 2件: ENTACAPONA; Entacapone1件: Entacapone 💬 1件: COMT 💬 3件: Dopaminergic synapse, Steroid hormone biosynthesis, Tyrosine metabolism 💬2件: 6, 17 💬
15 Exenatide 1件: Exenatide1件: Exenatide 💬 1件: GLP1R 💬 4件: Hormone signaling, Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬6件: 6, 17, 72, 78, 193, 233 💬
16 Exidavnemab 1件: Exidavnemab---2件: 6, 17 💬
17 Fipamezole 1件: Fipamezole---2件: 6, 17 💬
18 Fludrocortisone 1件: Fludrocortisone2件: Fludrocortisone acetate ,
Fludrocortisone 💬 		1件: NR3C2 💬 1件: Aldosterone-regulated sodium reabsorption 💬3件: 6, 17, 81 💬
19 Flumazenil 1件: Flumazenil1件: Flumazenil 💬 16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬 		9件: Cadherin signaling, GABAergic synapse, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬5件: 6, 13, 17, 18, 206 💬
20 Fluoxetine 3件: FLUOXETINE; FLUOXETINE HYDROCHLORIDE; Fluoxétine2件: Fluoxetine ,
Fluoxetine hydrochloride 💬 		1件: SLC6A4 💬 3件: Neuroactive ligand signaling, Serotonergic synapse, Synaptic vesicle cycle 💬3件: 13, 17, 86 💬
21 Flutemetamol 1件: Flutemetamol---6件: 2, 5, 6, 7, 17, 127 💬
22 Foralumab 1件: Foralumab---3件: 13, 17, 96 💬
23 Gold 1件: Gold---71件: 2, 5, 6, 11, 13, 17, 19, 21, 22, 28, 34, 35, 46, 49, 50, 53, 54, 56, 57, 58, 60, 63, 64, 65, 66, 68, 71, 75, 76, 77, 79, 84, 85, 86, 88, 91, 93, 95, 96, 97, 98, 107, 113, 127, 137, 158, 162, 167, 171, 193, 206, 215, 218, 222, 223, 224, 226, 227, 228, 230, 235, 271, 291, 294, 296, 298, 299, 310, 318, 331, 340 💬
24 Green tea leaf 1件: GREEN TEA LEAF1件: Green tea leaf 💬 --1件: 17 💬
25 Hydrogen 1件: Hydrogen---8件: 5, 6, 13, 17, 83, 97, 226, 238 💬
26 Idebenone 1件: Idebenone1件: Idebenone 💬 --9件: 6, 8, 13, 17, 18, 21, 113, 115, 302 💬
27 Inosine 1件: Inosine1件: Inosine 💬 --5件: 2, 6, 13, 17, 122 💬
28 Levodopa 2件: L-DOPA; Levodopa1件: Levodopa 💬 5件: DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬 		13件: Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬8件: 5, 6, 17, 90, 120, 140, 164, 201 💬
29 Lithium carbonate 1件: LITHIUM CARBONATE1件: Lithium carbonate 💬 --6件: 2, 13, 17, 18, 127, 310 💬
30 Losartan 2件: Losartan; LOSARTAN POTASSIUM2件: Losartan potassium ,
Losartan 💬 		1件: AGTR1 💬 17件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Hormone signaling, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬20件: 17, 19, 36, 46, 57, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 223, 299 💬
31 Metoprolol 2件: Metoprolol; Metoprolol Succinate4件: Metoprolol tartrate ,
Metoprolol succinate ,
Metoprolol ,
Metoprolol fumarate 💬 		1件: ADRB1 💬 13件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬6件: 17, 57, 58, 113, 193, 226 💬
32 Midodrine 2件: Midodrine; MIDODRINE HYDROCHLORIDE2件: Midodrine hydrochloride ,
Midodrine 💬 		3件: ADRA1A,
ADRA1B,
ADRA1D 💬 		9件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬3件: 6, 17, 58 💬
33 Nebivolol 1件: Nebivolol2件: Nebivolol ,
Nebivolol hydrochloride 💬 		1件: ADRB1 💬 13件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬4件: 17, 85, 113, 167 💬
34 Nicotinamide 2件: Niacinamide; Nicotinamide1件: Niacinamide 💬 --19件: 2, 5, 6, 7, 8, 17, 18, 21, 46, 49, 60, 63, 65, 85, 97, 107, 162, 191, 302 💬
35 Nicotinamide riboside 2件: Nicotinamide Riboside; Nicotinamide Riboside Chloride---14件: 2, 5, 6, 7, 8, 17, 18, 21, 49, 60, 65, 85, 97, 191 💬
36 Nitrogen 1件: Nitrogen1件: Nitrogen 💬 --6件: 5, 6, 17, 171, 211, 299 💬
37 Pseudoephedrine 1件: Pseudoephedrine4件: Pseudoephedrine hydrochloride ,
Pseudoephedrine polistirex ,
Pseudoephedrine sulfate ,
Pseudoephedrine 💬 		9件: ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬 		16件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 17 💬
38 Raclopride 1件: Raclopride---4件: 5, 6, 7, 17 💬
39 Rasagiline 2件: Rasagiline; Rasagiline mesylate3件: Rasagiline mesylate ,
Rasagiline ,
Rasagiline tartrate 💬 		1件: MAOB 💬 13件: Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬4件: 2, 5, 6, 17 💬
40 Riluzole 1件: RILUZOLE1件: Riluzole 💬 14件: GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬 		24件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Systemic lupus erythematosus, Transcriptional misregulation in cancer, cAMP signaling pathway 💬9件: 2, 3, 5, 8, 13, 17, 18, 203, 206 💬
41 Safinamide 2件: Safinamida; SAFINAMIDE2件: Safinamide ,
Safinamide mesylate 💬 		1件: MAOB 💬 13件: Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬2件: 6, 17 💬
42 Sirolimus 2件: Rapamycin; Sirolimus1件: Sirolimus 💬 1件: MTOR 💬 52件: AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, Integrated stress response (ISR) signaling pathway, Integrin signaling, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, Lysosome biogenesis, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬46件: 6, 13, 15, 17, 19, 21, 34, 35, 36, 46, 48, 49, 51, 54, 57, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 97, 98, 111, 127, 137, 157, 158, 192, 222, 223, 227, 277, 278, 279, 280, 281, 283, 285, 300, 331 💬
43 Tea leaf 1件: Tea leaf---1件: 17 💬
44 THK-5351 1件: THK-5351---5件: 5, 6, 7, 17, 127 💬
45 Tolterodine 1件: Tolterodine2件: Tolterodine ,
Tolterodine tartrate 💬 		1件: CHRM3 💬 12件: Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction 💬2件: 17, 53 💬
46 Trimethaphan 1件: Trimethaphan---1件: 17 💬
47 Ubiquinol 1件: Ubiquinol---4件: 6, 8, 17, 57 💬
48 Verdiperstat 1件: Verdiperstat1件: Verdiperstat 💬 1件: MPO 💬 5件: Acute myeloid leukemia, Drug metabolism - other enzymes, Neutrophil extracellular trap formation, Phagocytosis, Transcriptional misregulation in cancer 💬3件: 2, 17, 127 💬
49 Water 1件: Water1件: Water 💬 --36件: 2, 3, 5, 6, 13, 17, 19, 22, 35, 46, 49, 51, 53, 56, 57, 62, 63, 64, 65, 66, 67, 70, 72, 85, 86, 96, 97, 206, 215, 225, 226, 230, 240, 274, 278, 299 💬
50 YA-101 1件: YA-101---1件: 17 💬
51 Zoledronic acid 2件: Zoledronic acid; ZOLEDRONIC ACID MONOHYDRATE5件: Zoledronic acid ,
Zoledronate disodium ,
Zoledronate trisodium ,
Zoledronic acid ,
Zoledronic acid hemipentahydrate 💬 		1件: FDPS 💬 3件: Human T-cell leukemia virus 1 infection, Influenza A, Terpenoid backbone biosynthesis 💬16件: 5, 6, 13, 17, 46, 75, 77, 93, 95, 96, 97, 270, 274, 282, 299, 333 💬