Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank 薬物名（臨床試験情報から抽出） KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Acetylcysteine 1件: Acetylcysteine1件: Acetylcysteine 💬 --12件: 8, 34, 51, 53, 85, 90, 94, 97, 193, 233, 298, 299 💬
2 Anastrozole 1件: Anastrozole1件: Anastrozole 💬 1件: CYP19A 💬 2件: Ovarian steroidogenesis, Steroid hormone biosynthesis 💬3件: 78, 86, 193 💬
3 Cannabidiol 1件: Cannabidiol1件: Cannabidiol 💬 2件: CNR1,
CNR2 💬 		4件: Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬20件: 6, 8, 13, 19, 36, 46, 51, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬
4 Cannabidivarin 0件: ---1件: 193 💬
5 Carbetocin 1件: Carbetocin1件: Carbetocin 💬 1件: OXTR 💬 5件: Calcium signaling pathway, Hormone signaling, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, cAMP signaling pathway 💬1件: 193 💬
6 Diazoxide 2件: Diazoxide; Diazoxide choline2件: Diazoxide ,
Diazoxide choline 💬 		2件: ABCC8,
KCNJ11 💬 		4件: ABC transporters, GnRH secretion, Insulin secretion, Type II diabetes mellitus 💬2件: 13, 193 💬
7 Exenatide 1件: Exenatide1件: Exenatide 💬 1件: GLP1R 💬 4件: Hormone signaling, Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬5件: 6, 17, 78, 193, 233 💬
8 Guanfacine 0件: 2件: Guanfacine hydrochloride ,
Guanfacine 💬 		1件: ADRA2A 💬 4件: Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬1件: 193 💬
9 Liraglutide 1件: Liraglutide1件: Liraglutide 💬 1件: GLP1R 💬 4件: Hormone signaling, Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬5件: 6, 13, 75, 77, 193 💬
10 Livoletide 1件: Livoletide---1件: 193 💬
11 Medical air 1件: Medical AIR1件: Air, medical 💬 --6件: 58, 85, 86, 97, 193, 299 💬
12 Metoprolol 2件: Metoprolol; Metoprolol succinate4件: Metoprolol tartrate ,
Metoprolol succinate ,
Metoprolol ,
Metoprolol fumarate 💬 		1件: ADRB1 💬 13件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬6件: 17, 57, 58, 113, 193, 226 💬
13 NNZ-2591 1件: NNZ-2591---2件: 193, 201 💬
14 Octreotide 3件: Octreotida; Octreotide; Octreotide acetate4件: Octreotide ,
Octreotide acetate ,
Octreotide pamoate ,
Octreotide acetate 💬 		1件: SSTR2 💬 5件: Gastric acid secretion, Growth hormone synthesis, secretion and action, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬8件: 67, 75, 77, 84, 85, 89, 193, 227 💬
15 Oxytocin 1件: Oxytocin1件: Oxytocin 💬 1件: OXTR 💬 5件: Calcium signaling pathway, Hormone signaling, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, cAMP signaling pathway 💬8件: 6, 70, 72, 127, 168, 193, 206, 226 💬
16 Pitolisant 1件: Pitolisant2件: Pitolisant ,
Pitolisant hydrochloride 💬 		1件: HRH3 💬 2件: Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬3件: 6, 113, 193 💬
17 Rimonabant 1件: Rimonabant1件: Rimonabant 💬 1件: CNR1 💬 4件: Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬1件: 193 💬
18 Setmelanotide 1件: Setmelanotide2件: Setmelanotide ,
Setmelanotide acetate 💬 		1件: MC4R 💬 3件: Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬4件: 134, 193, 202, 265 💬
19 Sirolimus 2件: Rapamycin; Sirolimus1件: Sirolimus 💬 1件: MTOR 💬 49件: AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬46件: 2, 6, 13, 15, 17, 19, 21, 34, 35, 36, 46, 48, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 97, 98, 137, 157, 158, 192, 193, 222, 227, 256, 277, 278, 279, 280, 281, 283, 285, 300, 331 💬
20 Sodium chloride 2件: Natriumchlorid; Sodium chloride1件: Sodium chloride 💬 --23件: 2, 11, 13, 14, 34, 41, 46, 51, 53, 60, 67, 70, 96, 97, 193, 214, 215, 226, 227, 228, 288, 298, 299 💬
21 Somatotropin 7件: Growth hormone; Human growth hormone; Recombinant human growth hormone; Rhgh; Somatotropin; Somatropin; Somatropina1件: Somatropin 💬 1件: GHR 💬 6件: Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, Hormone signaling, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway 💬28件: 2, 3, 13, 19, 36, 46, 65, 74, 75, 76, 77, 78, 96, 97, 107, 113, 156, 187, 191, 193, 195, 238, 246, 265, 274, 276, 299, 337 💬
22 Tesofensine 2件: Tesofensine; Tesofensine citrate---2件: 6, 193 💬
23 Tirzepatide 1件: Tirzepatide1件: Tirzepatide 💬 2件: GIPR,
GLP1R 💬 		4件: Hormone signaling, Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬5件: 67, 96, 97, 193, 233 💬
24 Topiramate 1件: Topiramate1件: Topiramate 💬 36件: CA2,
CA4,
CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S,
GABRA,
GABRA,
GABRA,
GABRA,
GABRA,
GABRA,
GABRB,
GABRB,
GABRB,
GABRD,
GABRE,
GABRG,
GABRG,
GABRG,
GABRP,
GABRQ,
GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬 		53件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Arrhythmogenic right ventricular cardiomyopathy, Bile secretion, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Collecting duct acid secretion, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Gastric acid secretion, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Huntington disease, Hypertrophic cardiomyopathy, Insulin secretion, Long-term depression, Long-term potentiation, MAPK signaling pathway, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Nitrogen metabolism, Oxytocin signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Prion disease, Proximal tubule bicarbonate reclamation, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Spinocerebellar ataxia, Taste transduction, Tight junction, Transcriptional misregulation in cancer, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬5件: 6, 140, 144, 156, 193 💬
25 Ubidecarenone 2件: Coenzyme Q10; COQ101件: Ubidecarenone 💬 --14件: 2, 5, 6, 8, 10, 46, 57, 86, 96, 107, 113, 193, 214, 215 💬