Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank 薬物名（臨床試験情報から抽出） KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Ambrisentan 1件: Ambrisentan1件: Ambrisentan 💬 1件: EDNRA 💬 7件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬10件: 51, 66, 84, 85, 86, 88, 210, 211, 218, 222 💬
2 Atrasentan 1件: Atrasentan1件: Atrasentan hydrochloride 💬 1件: EDNRA 💬 7件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬3件: 66, 218, 222 💬
3 Bardoxolone 1件: Bardoxolone1件: Bardoxolone 💬 --7件: 66, 67, 84, 85, 86, 218, 222 💬
4 Bardoxolone methyl 1件: Bardoxolone methyl1件: Bardoxolone methyl 💬 --7件: 66, 67, 84, 85, 86, 218, 222 💬
5 Benazepril 1件: Benazepril2件: Benazepril hydrochloride ,
Benazepril 💬 		1件: ACE 💬 6件: Chagas disease, Coronavirus disease, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬5件: 49, 57, 218, 222, 224 💬
6 Dapagliflozin 1件: DAPAGLIFLOZIN1件: Dapagliflozin 💬 --16件: 6, 19, 28, 40, 41, 49, 57, 66, 67, 86, 88, 97, 210, 215, 218, 222 💬
7 ELX-02 1件: ELX-02---3件: 19, 218, 299 💬
8 Exaluren 1件: Exaluren---1件: 218 💬
9 Finerenone 1件: Finerenone1件: Finerenone 💬 1件: NR3C2 💬 1件: Aldosterone-regulated sodium reabsorption 💬5件: 66, 218, 222, 223, 224 💬
10 Fluvastatin 1件: Fluvastatin2件: Fluvastatin sodium ,
Fluvastatin 💬 		1件: HMGCR 💬 3件: AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬4件: 48, 79, 218, 222 💬
11 Gold 1件: Gold---71件: 2, 5, 6, 11, 13, 17, 19, 21, 22, 28, 34, 35, 46, 49, 50, 53, 54, 56, 57, 58, 60, 63, 64, 65, 66, 68, 71, 75, 76, 77, 79, 84, 85, 86, 88, 91, 93, 95, 96, 97, 98, 107, 113, 127, 137, 158, 162, 167, 171, 193, 206, 215, 218, 222, 223, 224, 226, 227, 228, 230, 235, 271, 291, 294, 296, 298, 299, 310, 318, 331, 340 💬
12 Henagliflozin 1件: Henagliflozin---3件: 58, 66, 218 💬
13 Hydroxychloroquine 2件: Hydroxychloroquine; HYDROXYCHLOROQUINE SULFATE2件: Hydroxychloroquine sulfate ,
Hydroxychloroquine 💬 		--29件: 6, 13, 34, 41, 43, 44, 45, 46, 48, 49, 53, 56, 63, 66, 84, 89, 90, 96, 97, 107, 218, 222, 223, 224, 234, 254, 271, 298, 299 💬
14 Lademirsen 1件: Lademirsen---1件: 218 💬
15 Metformin 4件: Metformin; Metformin hydrochloride; METFORMINA; Metformine2件: Metformin hydrochloride ,
Metformin 💬 		2件: PRKAA1,
PRKAA2 💬 		20件: AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬31件: 2, 6, 8, 13, 46, 49, 60, 65, 66, 67, 74, 75, 77, 81, 84, 85, 86, 97, 113, 127, 158, 206, 218, 222, 225, 233, 265, 285, 298, 299, 301 💬
16 Paricalcitol 1件: Paricalcitol1件: Paricalcitol 💬 1件: VDR 💬 5件: Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬5件: 19, 66, 218, 238, 298 💬
17 R3R01 1件: R3R01---2件: 218, 222 💬
18 Ramipril 1件: Ramipril1件: Ramipril 💬 1件: ACE 💬 6件: Chagas disease, Coronavirus disease, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬10件: 46, 49, 57, 66, 67, 113, 218, 222, 223, 257 💬
19 Setanaxib 1件: Setanaxib---2件: 93, 218 💬
20 Sparsentan 1件: SPARSENTAN1件: Sparsentan 💬 2件: AGTR1,
EDNRA 💬 		18件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Hormone signaling, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬4件: 66, 218, 222, 223 💬
21 Spironolactone 1件: Spironolactone1件: Spironolactone 💬 1件: NR3C2 💬 1件: Aldosterone-regulated sodium reabsorption 💬12件: 46, 57, 58, 67, 86, 113, 210, 214, 218, 222, 223, 225 💬
22 Valsartan 1件: Valsartan1件: Valsartan 💬 1件: AGTR1 💬 17件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Hormone signaling, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬11件: 28, 57, 58, 66, 75, 86, 210, 218, 222, 223, 224 💬
23 Vonafexor 1件: Vonafexor---1件: 218 💬