Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank 薬物名（臨床試験情報から抽出） KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Acetate 1件: Acetate---52件: 1, 2, 6, 10, 11, 13, 22, 35, 40, 46, 49, 51, 60, 63, 64, 65, 66, 67, 70, 71, 73, 75, 76, 77, 78, 79, 81, 83, 85, 86, 88, 89, 90, 96, 97, 113, 145, 156, 158, 162, 171, 206, 222, 223, 224, 225, 227, 235, 251, 265, 298, 299 💬
2 Acetazolamide 1件: ACETAZOLAMIDE2件: Acetazolamide ,
Acetazolamide sodium 💬 		13件: CA1,
CA12,
CA13,
CA14,
CA2,
CA3,
CA4,
CA5A,
CA5B,
CA6,
CA7,
CA8,
CA9 💬 		6件: Bile secretion, Collecting duct acid secretion, Gastric acid secretion, Nitrogen metabolism, Pancreatic secretion, Proximal tubule bicarbonate reclamation 💬8件: 13, 67, 90, 115, 155, 222, 225, 230 💬
3 AL-01211 0件: ---2件: 19, 67 💬
4 Amiloride 2件: Amiloride; Amiloride Hydrochloride2件: Amiloride hydrochloride ,
Amiloride 💬 		3件: SCNN1A,
SCNN1B,
SCNN1G 💬 		2件: Aldosterone-regulated sodium reabsorption, Taste transduction 💬5件: 13, 67, 222, 225, 299 💬
5 Aminohippuric acid 1件: Aminohippurate sodium2件: Aminohippurate sodium ,
Aminohippuric acid 💬 		--1件: 67 💬
6 Amiodarone 1件: Amiodarone2件: Amiodarone hydrochloride ,
Amiodarone 💬 		17件: ADRA1A,
ADRA1B,
ADRA1D,
ADRB1,
KCND3,
KCNJ11,
KCNJ12,
KCNJ3,
KCNJ5,
KCNJ8,
KCNQ1,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN8A,
SCN9A 💬 		36件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Cadherin signaling, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Dilated cardiomyopathy, Dopaminergic synapse, Estrogen signaling pathway, Gap junction, Gastric acid secretion, Glutamatergic synapse, GnRH secretion, Hormone signaling, IgSF CAM signaling, Insulin secretion, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, Pancreatic secretion, Protein digestion and absorption, Regulation of lipolysis in adipocytes, Renin secretion, Retrograde endocannabinoid signaling, Salivary secretion, Serotonergic synapse, Spinocerebellar ataxia, Taste transduction, Type II diabetes mellitus, Vascular smooth muscle contraction, Vibrio cholerae infection, cAMP signaling pathway, cGMP-PKG signaling pathway 💬3件: 28, 67, 127 💬
7 Amlodipine 1件: Amlodipine4件: Amlodipine besylate ,
Amlodipine maleate ,
Amlodipine ,
Amlodipine benzoate 💬 		4件: CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬 		37件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬6件: 51, 67, 79, 113, 222, 298 💬
8 Arginine 1件: Arginine3件: Arginine hydrochloride ,
Arginine ,
Arginine hydrochloride 💬 		--16件: 2, 21, 46, 57, 58, 67, 72, 96, 97, 98, 113, 210, 223, 225, 251, 299 💬
9 Atorvastatin 3件: ATORVASTATIN; Atorvastatin calcium; Atorvastatina2件: Atorvastatin calcium ,
Atorvastatin 💬 		1件: HMGCR 💬 3件: AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬21件: 13, 22, 46, 49, 51, 58, 63, 67, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬
10 Bardoxolone 1件: Bardoxolone1件: Bardoxolone 💬 --7件: 66, 67, 84, 85, 86, 218, 222 💬
11 Bardoxolone methyl 1件: Bardoxolone Methyl1件: Bardoxolone methyl 💬 --7件: 66, 67, 84, 85, 86, 218, 222 💬
12 Bempedoic acid 1件: Bempedoic acid1件: Bempedoic acid 💬 1件: ACLY 💬 1件: Citrate cycle (TCA cycle) 💬2件: 67, 79 💬
13 Bendroflumethiazide 1件: BENDROFLUMETHIAZIDE1件: Bendroflumethiazide 💬 1件: SLC12A3 💬 1件: Parathyroid hormone synthesis, secretion and action 💬1件: 67 💬
14 Bisoprolol 2件: Bisoprolol; Bisoprolol Fumarate2件: Bisoprolol fumarate ,
Bisoprolol 💬 		1件: ADRB1 💬 13件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬5件: 57, 58, 67, 86, 113 💬
15 Bosutinib 1件: Bosutinib2件: Bosutinib ,
Bosutinib hydrate 💬 		2件: ABL1,
SRC 💬 		50件: Adherens junction, Axon guidance, Bacterial invasion of epithelial cells, Bladder cancer, C-type lectin receptor signaling pathway, Cell cycle, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Chronic myeloid leukemia, Endocytosis, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Fluid shear stress and atherosclerosis, Focal adhesion, GABAergic synapse, Gap junction, GnRH signaling pathway, Hepatitis B, Herpes simplex virus 1 infection, Hormone signaling, Human cytomegalovirus infection, IgSF CAM signaling, Inflammatory mediator regulation of TRP channels, Integrin signaling, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, MicroRNAs in cancer, Mitophagy - animal, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Oxytocin signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Platelet activation, Prolactin signaling pathway, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Thyroid hormone signaling pathway, Tight junction, Tuberculosis, VEGF signaling pathway, Viral carcinogenesis, Viral myocarditis, Yersinia infection 💬2件: 2, 67 💬
16 Calcium 1件: Calcium---39件: 2, 3, 6, 13, 15, 19, 46, 48, 49, 51, 53, 56, 62, 67, 68, 71, 74, 75, 79, 84, 90, 93, 94, 95, 96, 97, 156, 186, 214, 215, 222, 224, 235, 256, 265, 271, 274, 298, 299 💬
17 Candesartan 1件: CANDESARTAN1件: Candesartan 💬 1件: AGTR1 💬 17件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Hormone signaling, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬4件: 57, 58, 67, 222 💬
18 Cilnidipine 1件: Cilnidipine1件: Cilnidipine 💬 5件: CACNA1B,
CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬 		41件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Huntington disease, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Morphine addiction, Nicotine addiction, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Synaptic vesicle cycle, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 67 💬
19 Curcumin 1件: Curcumin---12件: 2, 13, 34, 36, 46, 67, 74, 94, 96, 97, 139, 299 💬
20 Cyclosporine 7件: CICLOSPORIN; CICLOSPORINA; Ciclosporine; Cyclosporin; Cyclosporin A; Cyclosporine; Cyclosporine A1件: Cyclosporine 💬 5件: PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬 		33件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬39件: 11, 14, 19, 20, 28, 36, 40, 41, 42, 45, 46, 49, 50, 53, 56, 58, 60, 61, 62, 63, 64, 65, 67, 90, 95, 97, 107, 118, 162, 164, 222, 223, 226, 228, 234, 283, 284, 285, 302 💬
21 Dapagliflozin 1件: Dapagliflozin1件: Dapagliflozin 💬 --16件: 6, 19, 28, 40, 41, 49, 57, 66, 67, 86, 88, 97, 210, 215, 218, 222 💬
22 Digoxin 1件: Digoxin1件: Digoxin 💬 4件: ATP1A1,
ATP1A2,
ATP1A3,
ATP1A4 💬 		19件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Aldosterone-regulated sodium reabsorption, Bile secretion, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cytoskeleton in muscle cells, Endocrine and other factor-regulated calcium reabsorption, Gastric acid secretion, Insulin secretion, Mineral absorption, Pancreatic secretion, Protein digestion and absorption, Proximal tubule bicarbonate reclamation, Salivary secretion, Thyroid hormone signaling pathway, Thyroid hormone synthesis, cAMP signaling pathway, cGMP-PKG signaling pathway 💬7件: 2, 8, 46, 57, 65, 67, 210 💬
23 Doxazosin 1件: DOXAZOSIN2件: Doxazosin mesylate ,
Doxazosin 💬 		3件: ADRA1A,
ADRA1B,
ADRA1D 💬 		9件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬2件: 57, 67 💬
24 Efavirenz 1件: Efavirenz1件: Efavirenz 💬 --3件: 23, 67, 265 💬
25 Emodin 1件: Emodin---1件: 67 💬
26 Empagliflozin 1件: Empagliflozin1件: Empagliflozin 💬 --17件: 28, 46, 57, 58, 65, 67, 72, 77, 86, 96, 97, 113, 222, 223, 257, 298, 299 💬
27 Everolimus 1件: EVEROLIMUS1件: Everolimus 💬 1件: MTOR 💬 52件: AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, Integrated stress response (ISR) signaling pathway, Integrin signaling, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, Lysosome biogenesis, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬12件: 34, 67, 89, 96, 137, 157, 158, 228, 277, 278, 279, 280 💬
28 Febuxostat 1件: Febuxostat2件: Febuxostat ,
Febuxostat hydrate 💬 		1件: XDH 💬 4件: Caffeine metabolism, Drug metabolism - other enzymes, Peroxisome, Purine metabolism 💬5件: 2, 6, 13, 67, 97 💬
29 Fluconazole 2件: Diflucan; FLUCONAZOLE1件: Fluconazole 💬 --3件: 67, 96, 225 💬
30 Hydralazine 1件: Hydralazine3件: Hydralazine hydrochloride ,
Hydralazine polistirex ,
Hydralazine 💬 		1件: AOC3 💬 4件: Glycine, serine and threonine metabolism, Phenylalanine metabolism, Tyrosine metabolism, beta-Alanine metabolism 💬1件: 67 💬
31 Hydrochlorothiazide 1件: HYDROCHLOROTHIAZIDE1件: Hydrochlorothiazide 💬 1件: SLC12A3 💬 1件: Parathyroid hormone synthesis, secretion and action 💬5件: 13, 67, 222, 225, 235 💬
32 Imidapril 1件: Imidapril2件: Imidapril hydrochloride ,
Imidapril 💬 		1件: ACE 💬 6件: Chagas disease, Coronavirus disease, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬1件: 67 💬
33 Iohexol 1件: Iohexol1件: Iohexol 💬 --2件: 19, 67 💬
34 Itraconazole 1件: Itraconazole1件: Itraconazole 💬 --13件: 2, 3, 6, 46, 65, 67, 96, 97, 137, 158, 227, 299, 309 💬
35 L-arginine 1件: L-arginine---10件: 2, 21, 46, 67, 96, 97, 98, 113, 223, 299 💬
36 Lanreotide 3件: LANREOTIDA; Lanreotide; LANREOTIDE ACETATE1件: Lanreotide acetate 💬 2件: SSTR2,
SSTR5 💬 		5件: Gastric acid secretion, Growth hormone synthesis, secretion and action, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬5件: 67, 73, 77, 85, 298 💬
37 Lisinopril 1件: Lisinopril2件: Lisinopril ,
Lisinopril 💬 		1件: ACE 💬 6件: Chagas disease, Coronavirus disease, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬9件: 19, 46, 49, 57, 66, 67, 113, 222, 223 💬
38 Lixivaptan 1件: Lixivaptan1件: Lixivaptan 💬 1件: AVPR2 💬 4件: Hormone signaling, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬1件: 67 💬
39 Losartan 2件: Losartan; LOSARTAN POTASSIUM2件: Losartan potassium ,
Losartan 💬 		1件: AGTR1 💬 17件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Hormone signaling, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬20件: 17, 19, 36, 46, 57, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 223, 299 💬
40 Metformin 4件: METFORMIN; METFORMIN HYDROCHLORIDE; METFORMINA; Metformine2件: Metformin hydrochloride ,
Metformin 💬 		2件: PRKAA1,
PRKAA2 💬 		20件: AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬31件: 2, 6, 8, 13, 46, 49, 60, 65, 66, 67, 74, 75, 77, 81, 84, 85, 86, 97, 113, 127, 158, 206, 218, 222, 225, 233, 265, 285, 298, 299, 301 💬
41 Midazolam 1件: Midazolam3件: Midazolam ,
Midazolam hydrochloride ,
Midazolam maleate 💬 		16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬 		9件: Cadherin signaling, GABAergic synapse, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬14件: 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
42 Nitrate 1件: Nitrate1件: Nitric acid 💬 --6件: 57, 58, 67, 85, 113, 299 💬
43 Octreotide 4件: OCTREOTIDA; Octreotide; OCTREOTIDE ACETATE; OCTREOTIDE HYDROCHLORIDE5件: Octreotide ,
Octreotide acetate ,
Octreotide pamoate ,
Octreotide acetate ,
Octreotide hydrochloride 💬 		1件: SSTR2 💬 5件: Gastric acid secretion, Growth hormone synthesis, secretion and action, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬8件: 67, 75, 77, 84, 85, 89, 193, 227 💬
44 Omeprazole 3件: Omeprazol; Omeprazole; OMEPRAZOLE MAGNESIUM3件: Omeprazole ,
Omeprazole sodium ,
Omeprazole magnesium 💬 		2件: ATP4A,
ATP4B 💬 		3件: Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation 💬18件: 6, 8, 13, 21, 46, 51, 67, 85, 90, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
45 Pasireotide 4件: Pasireotida; PASIREOTIDE; PASIREOTIDE DIASPARTATE; PASIREOTIDE PAMOATE3件: Pasireotide ,
Pasireotide diaspartate ,
Pasireotide pamoate 💬 		4件: SSTR1,
SSTR2,
SSTR3,
SSTR5 💬 		5件: Gastric acid secretion, Growth hormone synthesis, secretion and action, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬4件: 67, 74, 75, 77 💬
46 Pemafibrate 1件: Pemafibrate1件: Pemafibrate 💬 1件: PPARA 💬 10件: Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬2件: 67, 93 💬
47 Pioglitazone 1件: Pioglitazone2件: Pioglitazone hydrochloride ,
Pioglitazone 💬 		1件: PPARG 💬 12件: AMPK signaling pathway, Efferocytosis, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬17件: 2, 6, 13, 15, 20, 46, 49, 65, 67, 81, 86, 96, 223, 229, 265, 298, 299 💬
48 Potassium 1件: Potassium1件: Potassium 💬 --17件: 36, 46, 57, 58, 66, 67, 88, 93, 94, 97, 98, 115, 167, 179, 215, 223, 235 💬
49 Pravastatin 2件: Pravastatin; Pravastatin sodium2件: Pravastatin sodium ,
Pravastatin 💬 		1件: HMGCR 💬 3件: AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬11件: 13, 46, 49, 67, 79, 96, 164, 210, 222, 265, 333 💬
50 Pyruvic acid 1件: SODIUM PYRUVATE---6件: 2, 21, 67, 85, 299, 318 💬
51 Ramipril 1件: Ramipril1件: Ramipril 💬 1件: ACE 💬 6件: Chagas disease, Coronavirus disease, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬10件: 46, 49, 57, 66, 67, 113, 218, 222, 223, 257 💬
52 RGLS-8429 0件: ---1件: 67 💬
53 Rosuvastatin 2件: Rosuvastatin; ROSUVASTATIN CALCIUM2件: Rosuvastatin calcium ,
Rosuvastatin 💬 		1件: HMGCR 💬 3件: AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬16件: 6, 18, 46, 49, 51, 56, 57, 62, 65, 67, 79, 94, 96, 97, 271, 299 💬
54 Rotigotine 3件: Rotigotina; Rotigotine; Rotigotine hydrochloride1件: Rotigotine 💬 1件: DRD2 💬 10件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬3件: 6, 67, 127 💬
55 Sirolimus 2件: Rapamycin; SIROLIMUS1件: Sirolimus 💬 1件: MTOR 💬 52件: AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, Integrated stress response (ISR) signaling pathway, Integrin signaling, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, Lysosome biogenesis, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬46件: 6, 13, 15, 17, 19, 21, 34, 35, 36, 46, 48, 49, 51, 54, 57, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 97, 98, 111, 127, 137, 157, 158, 192, 222, 223, 227, 277, 278, 279, 280, 281, 283, 285, 300, 331 💬
56 Sodium bicarbonate 2件: SODIO BICARBONATO; Sodium bicarbonate1件: Sodium bicarbonate 💬 --4件: 67, 97, 226, 299 💬
57 Sodium chloride 3件: NaCl; Sodium Chloride; Sodium Chloride solution1件: Sodium chloride 💬 --31件: 2, 6, 11, 13, 14, 22, 34, 41, 46, 50, 51, 53, 60, 65, 67, 70, 85, 96, 97, 124, 168, 193, 214, 215, 226, 227, 228, 271, 288, 298, 299 💬
58 Sodium citrate 1件: Sodium citrate1件: Sodium citrate 💬 --4件: 67, 214, 215, 235 💬
59 Somatostatin 1件: Somatostatin1件: Somatostatin 💬 5件: SSTR1,
SSTR2,
SSTR3,
SSTR4,
SSTR5 💬 		5件: Gastric acid secretion, Growth hormone synthesis, secretion and action, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬2件: 67, 77 💬
60 Spironolactone 1件: Spironolactone1件: Spironolactone 💬 1件: NR3C2 💬 1件: Aldosterone-regulated sodium reabsorption 💬12件: 46, 57, 58, 67, 86, 113, 210, 214, 218, 222, 223, 225 💬
61 Tamibarotene 1件: Tamibarotene1件: Tamibarotene 💬 1件: RARA 💬 5件: Acute myeloid leukemia, Estrogen signaling pathway, Pathways in cancer, Th17 cell differentiation, Transcriptional misregulation in cancer 💬3件: 26, 67, 96 💬
62 Telmisartan 1件: Telmisartan1件: Telmisartan 💬 1件: AGTR1 💬 17件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Hormone signaling, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬5件: 6, 57, 66, 67, 222 💬
63 Tesevatinib 1件: Tesevatinib1件: Tesevatinib 💬 5件: EGFR,
EPHB4,
ERBB2,
FLT4,
KDR 💬 		54件: Adherens junction, Axon guidance, Bladder cancer, Breast cancer, Cadherin signaling, Calcium signaling pathway, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Coronavirus disease, Cushing syndrome, Endocytosis, Endometrial cancer, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Fluid shear stress and atherosclerosis, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH signaling pathway, HIF-1 signaling pathway, Hepatitis C, Hepatocellular carcinoma, Human cytomegalovirus infection, Human papillomavirus infection, IgSF CAM signaling, Integrin signaling, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, Non-small cell lung cancer, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Tight junction, VEGF signaling pathway, Virion - Hepatitis viruses 💬1件: 67 💬
64 Tirzepatide 1件: Tirzepatide1件: Tirzepatide 💬 2件: GIPR,
GLP1R 💬 		4件: Hormone signaling, Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬6件: 67, 96, 97, 193, 233, 265 💬
65 Tolvaptan 1件: TOLVAPTAN1件: Tolvaptan 💬 1件: AVPR2 💬 4件: Hormone signaling, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬5件: 67, 72, 86, 222, 225 💬
66 Triptolide 1件: Triptolide---1件: 67 💬
67 Ursodeoxycholic acid 3件: UDCA; URSODEOXYCHOLIC ACID; Ursodiol1件: Ursodiol 💬 1件: NR1H4 💬 1件: Bile secretion 💬10件: 6, 46, 67, 84, 93, 94, 95, 96, 97, 296 💬
68 Venglustat 2件: Venglustat; Venglustat malate2件: Venglustat ,
Venglustat malate 💬 		1件: UGCG 💬 2件: Cornified envelope formation, Sphingolipid metabolism 💬3件: 6, 19, 67 💬
69 Water 1件: Water1件: Water 💬 --36件: 2, 3, 5, 6, 13, 17, 19, 22, 35, 46, 49, 51, 53, 56, 57, 62, 63, 64, 65, 66, 67, 70, 72, 85, 86, 96, 97, 206, 215, 225, 226, 230, 240, 274, 278, 299 💬