Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank 薬物名（臨床試験情報から抽出） KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Abiraterone 1件: Abiraterone acetate1件: Abiraterone acetate 💬 1件: CYP17A 💬 5件: Cortisol synthesis and secretion, Cushing syndrome, Ovarian steroidogenesis, Prolactin signaling pathway, Steroid hormone biosynthesis 💬2件: 75, 81 💬
2 Alprazolam 1件: Alprazolam1件: Alprazolam 💬 16件: GABRA,
GABRA,
GABRA,
GABRA,
GABRA,
GABRA,
GABRB,
GABRB,
GABRB,
GABRD,
GABRE,
GABRG,
GABRG,
GABRG,
GABRP,
GABRQ 💬 		8件: GABAergic synapse, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬2件: 8, 75 💬
3 Bexarotene 1件: Bexarotene1件: Bexarotene 💬 3件: RXRA,
RXRB,
RXRG 💬 		18件: Adipocytokine signaling pathway, Bile secretion, Chemical carcinogenesis - receptor activation, Efferocytosis, Gastric cancer, Hepatitis C, Lipid and atherosclerosis, Non-alcoholic fatty liver disease, Non-small cell lung cancer, PI3K-Akt signaling pathway, PPAR signaling pathway, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Thyroid cancer, Thyroid hormone signaling pathway, Transcriptional misregulation in cancer 💬2件: 13, 75 💬
4 Cabergoline 2件: Cabergolina; Cabergoline1件: Cabergoline 💬 2件: DRD2,
PRL 💬 		14件: Alcoholism, Cocaine addiction, Cytokine-cytokine receptor interaction, Dopaminergic synapse, Gap junction, Hormone signaling, JAK-STAT signaling pathway, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Parkinson disease, Prolactin signaling pathway, Rap1 signaling pathway, cAMP signaling pathway 💬4件: 6, 74, 75, 77 💬
5 Calcium 2件: Calcio; Calcium---24件: 6, 13, 19, 46, 49, 51, 53, 68, 75, 84, 93, 95, 96, 97, 156, 186, 214, 215, 222, 235, 271, 274, 298, 299 💬
6 Calcium carbonate 1件: Calcium carbonate2件: Calcium carbonate ,
Calcium carbonate 💬 		--10件: 13, 19, 46, 53, 75, 96, 97, 235, 274, 299 💬
7 Corticorelin 1件: Corticotropin-releasing hormone1件: Corticorelin 💬 2件: CRHR1,
CRHR2 💬 		5件: Cushing syndrome, Hormone signaling, Long-term depression, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬2件: 75, 205 💬
8 Corticotropin 3件: Acth; Adrenocorticotropic hormone; Corticotropin2件: Corticotropin ,
Corticotropin, repository 💬 		1件: MC2R 💬 6件: Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬11件: 13, 46, 50, 66, 75, 78, 81, 84, 145, 205, 222 💬
9 Dabigatran 1件: Dabigatran1件: Dabigatran 💬 1件: F2 💬 8件: Complement and coagulation cascades, Coronavirus disease - COVID-19, Neuroactive ligand-receptor interaction, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Platelet activation, Regulation of actin cytoskeleton 💬5件: 51, 75, 85, 91, 124 💬
10 Dabigatran etexilate 1件: Dabigatran etexilate2件: Dabigatran etexilate mesylate ,
Dabigatran etexilate 💬 		1件: F2 💬 8件: Complement and coagulation cascades, Coronavirus disease - COVID-19, Neuroactive ligand-receptor interaction, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Platelet activation, Regulation of actin cytoskeleton 💬2件: 51, 75 💬
11 Denosumab 1件: Denosumab1件: Denosumab 💬 1件: TNFSF11 💬 8件: Breast cancer, Chemical carcinogenesis - receptor activation, Cytokine-cytokine receptor interaction, NF-kappa B signaling pathway, Osteoclast differentiation, Parathyroid hormone synthesis, secretion and action, Prolactin signaling pathway, Rheumatoid arthritis 💬10件: 46, 50, 70, 75, 77, 93, 95, 96, 274, 299 💬
12 Desmopressin 4件: Ddavp; Desmopressin; Desmopressin acetate; Desmopressine2件: Desmopressin ,
Desmopressin acetate 💬 		2件: AVPR2,
F8 💬 		5件: Complement and coagulation cascades, Hormone signaling, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬6件: 6, 64, 72, 75, 225, 288 💬
13 Dexamethasone 2件: Dexamethasone; Dexamethasone sodium phosphate3件: Dexamethasone ,
Dexamethasone sodium phosphate ,
Dexamethasone phosphate 💬 		1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬25件: 13, 14, 16, 19, 28, 35, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 296, 299, 331 💬
14 Dotatate 0件: ---1件: 75 💬
15 Dotatate gallium Ga-68 1件: 68GA-dotatate1件: Edotreotide gallium Ga-68 💬 1件: SSTR2 💬 5件: Gastric acid secretion, Growth hormone synthesis, secretion and action, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬4件: 19, 75, 84, 238 💬
16 Eplerenone 1件: Eplerenone1件: Eplerenone 💬 1件: NR3C2 💬 1件: Aldosterone-regulated sodium reabsorption 💬4件: 75, 113, 210, 215 💬
17 Fenvalerate 1件: Pyridin1件: Fenvalerate 💬 --1件: 75 💬
18 Fimepinostat 1件: Fimepinostat1件: Fimepinostat 💬 11件: HDAC10,
HDAC1_2,
HDAC1_2,
HDAC3,
HDAC4_5,
HDAC4_5,
HDAC6,
HDAC7,
HDAC8,
HDAC9,
PIK3C3 💬 		32件: ATP-dependent chromatin remodeling, Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Cell cycle, Chronic myeloid leukemia, Epstein-Barr virus infection, Human papillomavirus infection, Huntington disease, Inositol phosphate metabolism, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, Notch signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phagosome, Phosphatidylinositol signaling system, Polycomb repressive complex, Salmonella infection, Shigellosis, Spinocerebellar ataxia, TGF-beta signaling pathway, Thyroid hormone signaling pathway, Transcriptional misregulation in cancer, Tuberculosis, Viral carcinogenesis 💬1件: 75 💬
19 Gefitinib 1件: Gefitinib1件: Gefitinib 💬 1件: EGFR 💬 47件: Adherens junction, Bladder cancer, Breast cancer, Calcium signaling pathway, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Coronavirus disease - COVID-19, Cushing syndrome, Endocytosis, Endometrial cancer, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH signaling pathway, HIF-1 signaling pathway, Hepatitis C, Hepatocellular carcinoma, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, Non-small cell lung cancer, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Virion - Hepatitis viruses 💬1件: 75 💬
20 Hydrocortisone 3件: Cortisol; Hydrocortisone; Hydrocortisonum1件: Hydrocortisone 💬 1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬11件: 6, 41, 46, 53, 75, 78, 81, 83, 97, 98, 299 💬
21 Ketoconazole 1件: Ketoconazole1件: Ketoconazole 💬 --2件: 13, 75 💬
22 Lapatinib 1件: Lapatinib2件: Lapatinib ditosylate ,
Lapatinib 💬 		2件: EGFR,
ERBB2 💬 		48件: Adherens junction, Bladder cancer, Breast cancer, Calcium signaling pathway, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Coronavirus disease - COVID-19, Cushing syndrome, Endocytosis, Endometrial cancer, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH signaling pathway, HIF-1 signaling pathway, Hepatitis C, Hepatocellular carcinoma, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, Non-small cell lung cancer, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Tight junction, Virion - Hepatitis viruses 💬3件: 34, 74, 75 💬
23 Levoketoconazole 1件: Levoketoconazole1件: Levoketoconazole 💬 3件: CYP11A,
CYP11B1,
CYP17A 💬 		6件: Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Ovarian steroidogenesis, Prolactin signaling pathway, Steroid hormone biosynthesis 💬1件: 75 💬
24 Liraglutide 1件: Liraglutide1件: Liraglutide 💬 1件: GLP1R 💬 4件: Hormone signaling, Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬5件: 6, 13, 75, 77, 193 💬
25 Metformin 3件: Metformin; Metformin hydrochloride; Metformina2件: Metformin hydrochloride ,
Metformin 💬 		2件: PRKAA,
PRKAA 💬 		20件: AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬28件: 2, 6, 8, 13, 46, 49, 60, 65, 66, 67, 75, 77, 81, 84, 86, 97, 113, 127, 158, 206, 218, 222, 225, 265, 285, 298, 299, 301 💬
26 Methionine 1件: Methionine1件: Methionine 💬 --7件: 34, 75, 84, 94, 229, 298, 300 💬
27 Methionine C-11 1件: Methionine---1件: 75 💬
28 Metyrapone 1件: Metyrapone1件: Metyrapone 💬 1件: CYP11B1 💬 3件: Cortisol synthesis and secretion, Cushing syndrome, Steroid hormone biosynthesis 💬1件: 75 💬
29 Mifepristone 1件: Mifepristone1件: Mifepristone 💬 2件: NR3C1,
PGR 💬 		6件: Breast cancer, Chemical carcinogenesis - receptor activation, Estrogen signaling pathway, Neuroactive ligand-receptor interaction, Oocyte meiosis, Progesterone-mediated oocyte maturation 💬1件: 75 💬
30 Nevanimibe 1件: Nevanimibe hydrochloride2件: Nevanimibe ,
Nevanimibe hydrochloride 💬 		--2件: 75, 81 💬
31 Octreotide 3件: Octreotida; Octreotide; Octreotide acetate4件: Octreotide ,
Octreotide acetate ,
Octreotide pamoate ,
Octreotide acetate 💬 		1件: SSTR2 💬 5件: Gastric acid secretion, Growth hormone synthesis, secretion and action, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬8件: 67, 75, 77, 84, 85, 89, 193, 227 💬
32 Osilodrostat 1件: Osilodrostat2件: Osilodrostat ,
Osilodrostat phosphate 💬 		1件: CYP11B2 💬 2件: Aldosterone synthesis and secretion, Steroid hormone biosynthesis 💬1件: 75 💬
33 Pasireotide 4件: Pasireotida; Pasireotide; Pasireotide diaspartate; Pasireotide pamoate3件: Pasireotide ,
Pasireotide diaspartate ,
Pasireotide pamoate 💬 		4件: SSTR1,
SSTR2,
SSTR3,
SSTR5 💬 		5件: Gastric acid secretion, Growth hormone synthesis, secretion and action, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬4件: 67, 74, 75, 77 💬
34 Pentetreotide 1件: Pentetreotide1件: Pentetreotide 💬 --1件: 75 💬
35 Phenylalanine 1件: Phenylalanine1件: Phenylalanine 💬 --3件: 75, 77, 240 💬
36 Phosphate ion 1件: Phosphate---13件: 3, 13, 46, 49, 65, 70, 75, 90, 235, 238, 256, 286, 288 💬
37 Pyrazole 2件: 1H-pyrazol; Pyrazole---3件: 2, 58, 75 💬
38 Relacorilant 2件: CORT125134; Relacorilant1件: Relacorilant 💬 1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬1件: 75 💬
39 Rosiglitazone 2件: Rosiglitazone; Rosiglitazone maleate2件: Rosiglitazone maleate ,
Rosiglitazone 💬 		1件: NR1C3 💬 12件: AMPK signaling pathway, Efferocytosis, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬6件: 46, 75, 77, 97, 222, 265 💬
40 Seliciclib 2件: R-roscovitine; Seliciclib---2件: 75, 299 💬
41 Sitagliptin 1件: Sitagliptin3件: Sitagliptin phosphate ,
Sitagliptin ,
Sitagliptin phosphate 💬 		1件: DPP4 💬 2件: Protein digestion and absorption, Virion - Hepatitis viruses 💬5件: 6, 75, 77, 233, 299 💬
42 Somatotropin 7件: Growth hormone; Human growth hormone; Recombinant human growth hormone; Rhgh; Somatotropin; Somatropin; Somatropina1件: Somatropin 💬 1件: GHR 💬 6件: Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, Hormone signaling, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway 💬28件: 2, 3, 13, 19, 36, 46, 65, 74, 75, 76, 77, 78, 96, 97, 107, 113, 156, 187, 191, 193, 195, 238, 246, 265, 274, 276, 299, 337 💬
43 Tadalafil 2件: Tadalafil; Tadalafilo1件: Tadalafil 💬 1件: PDE5 💬 2件: Purine metabolism, cGMP-PKG signaling pathway 💬8件: 6, 51, 75, 77, 84, 86, 113, 210 💬
44 Tretinoin 3件: Atra; Tretinoin; Tretinoina1件: Tretinoin 💬 3件: PML,
RARA,
RARB 💬 		12件: Acute myeloid leukemia, Endocytosis, Estrogen signaling pathway, Gastric cancer, Herpes simplex virus 1 infection, Influenza A, Non-small cell lung cancer, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Transcriptional misregulation in cancer, Ubiquitin mediated proteolysis 💬6件: 2, 62, 63, 75, 94, 231 💬
45 Tryptophan 2件: Propanoic acid; Tryptophan1件: Tryptophan 💬 --4件: 6, 46, 75, 77 💬
46 Tyrosine 3件: Alanine; Propanoic acid; Tyrosine1件: Tyrosine 💬 --5件: 6, 75, 77, 86, 298 💬
47 Valsartan 1件: Valsartan1件: Valsartan 💬 1件: AGTR1 💬 17件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Hormone signaling, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬8件: 57, 58, 66, 75, 86, 210, 222, 224 💬
48 Vorinostat 1件: Vorinostat1件: Vorinostat 💬 11件: HDAC10,
HDAC11,
HDAC1_2,
HDAC1_2,
HDAC3,
HDAC4_5,
HDAC4_5,
HDAC6,
HDAC7,
HDAC8,
HDAC9 💬 		20件: ATP-dependent chromatin remodeling, Alcoholism, Amphetamine addiction, Amyotrophic lateral sclerosis, Apelin signaling pathway, Cell cycle, Chronic myeloid leukemia, Epstein-Barr virus infection, Human papillomavirus infection, Huntington disease, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, Notch signaling pathway, Pathways in cancer, Polycomb repressive complex, TGF-beta signaling pathway, Thyroid hormone signaling pathway, Transcriptional misregulation in cancer, Viral carcinogenesis 💬2件: 75, 96 💬
49 Zoledronic acid 3件: Zoledronate; Zoledronic acid; Zoledronic acid monohydrate5件: Zoledronic acid ,
Zoledronate disodium ,
Zoledronate trisodium ,
Zoledronic acid ,
Zoledronic acid hemipentahydrate 💬 		1件: FDPS 💬 3件: Human T-cell leukemia virus 1 infection, Influenza A, Terpenoid backbone biosynthesis 💬16件: 5, 6, 13, 17, 46, 65, 75, 77, 93, 95, 96, 97, 270, 274, 299, 333 💬