Drug Description in Trials / DrugBank / KEGG DRUG


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No. KEGG DRUG DrugBank 薬物名(臨床試験情報から抽出) KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Abatacept 💬1件: Abatacept1件: Abatacept2件: CD80,
CD86 💬
13件: Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules, Graft-versus-host disease, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Rheumatoid arthritis, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis, Virion - Adenovirus 💬26件: 2, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
2 Azathioprine 💬1件: Azathioprine2件: Azathioprine; Azatioprina--22件: 6, 11, 13, 19, 35, 42, 43, 44, 45, 46, 49, 55, 63, 65, 66, 84, 85, 94, 95, 96, 97, 162 💬
3 Azathioprine sodium 💬1件: Azathioprine2件: Azathioprine; Azatioprina--22件: 6, 11, 13, 19, 35, 42, 43, 44, 45, 46, 49, 55, 63, 65, 66, 84, 85, 94, 95, 96, 97, 162 💬
4 Belimumab 💬1件: Belimumab1件: Belimumab1件: TNFSF13B 💬 4件: Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬13件: 11, 13, 43, 44, 46, 49, 51, 53, 63, 66, 95, 222, 296 💬
5 Budesonide 💬1件: Budesonide1件: Budesonide1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬7件: 66, 93, 94, 95, 96, 97, 98 💬
6 Cannabidiol 💬1件: Cannabidiol1件: Cannabidiol2件: CNR1,
CNR2 💬
4件: Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬18件: 6, 8, 13, 19, 36, 46, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 271 💬
7 Chloroquine 💬1件: Chloroquine1件: Chloroquine--1件: 46 💬
8 Chloroquine hydrochloride 💬1件: Chloroquine1件: Chloroquine--1件: 46 💬
9 Chloroquine phosphate 💬1件: Chloroquine1件: Chloroquine--1件: 46 💬
10 Chloroquine sulfate 💬1件: Chloroquine1件: Chloroquine--1件: 46 💬
11 Cyclosporine 💬1件: Cyclosporine6件: Ciclosporin; Ciclosporina; Ciclosporine; Cyclosporin; Cyclosporin A; Cyclosporine5件: PPP3C,
PPP3C,
PPP3C,
PPP3R,
PPP3R 💬
33件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬37件: 11, 26, 28, 40, 41, 42, 45, 46, 49, 50, 53, 54, 55, 56, 60, 61, 62, 63, 64, 65, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 269, 274, 283, 284, 285, 302, 326 💬
12 Denosumab 💬1件: Denosumab1件: Denosumab1件: TNFSF11 💬 8件: Breast cancer, Chemical carcinogenesis - receptor activation, Cytokine-cytokine receptor interaction, NF-kappa B signaling pathway, Osteoclast differentiation, Parathyroid hormone synthesis, secretion and action, Prolactin signaling pathway, Rheumatoid arthritis 💬10件: 46, 50, 70, 75, 77, 93, 95, 96, 274, 299 💬
13 Efalizumab 💬1件: Efalizumab1件: Efalizumab1件: ITGAL 💬 12件: Cell adhesion molecules, Epstein-Barr virus infection, Human T-cell leukemia virus 1 infection, Leukocyte transendothelial migration, Malaria, Natural killer cell mediated cytotoxicity, Neutrophil extracellular trap formation, Rap1 signaling pathway, Regulation of actin cytoskeleton, Rheumatoid arthritis, Staphylococcus aureus infection, Viral myocarditis 💬9件: 11, 13, 37, 46, 53, 61, 95, 96, 221 💬
14 Epoetin alfa 💬1件: Erythropoietin2件: Epoetin alfa; Erythropoietin1件: EPOR 💬 7件: Cytokine-cytokine receptor interaction, Efferocytosis, Hematopoietic cell lineage, Hormone signaling, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬11件: 2, 6, 13, 18, 22, 46, 47, 61, 70, 95, 96 💬
15 Epoetin epsilon 💬1件: Erythropoietin2件: Epoetin alfa; Erythropoietin1件: EPOR 💬 7件: Cytokine-cytokine receptor interaction, Efferocytosis, Hematopoietic cell lineage, Hormone signaling, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬11件: 2, 6, 13, 18, 22, 46, 47, 61, 70, 95, 96 💬
16 Epoetin theta 💬1件: Erythropoietin2件: Epoetin alfa; Erythropoietin1件: EPOR 💬 7件: Cytokine-cytokine receptor interaction, Efferocytosis, Hematopoietic cell lineage, Hormone signaling, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬11件: 2, 6, 13, 18, 22, 46, 47, 61, 70, 95, 96 💬
17 Epoetin zeta 💬1件: Erythropoietin2件: Epoetin alfa; Erythropoietin1件: EPOR 💬 7件: Cytokine-cytokine receptor interaction, Efferocytosis, Hematopoietic cell lineage, Hormone signaling, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬11件: 2, 6, 13, 18, 22, 46, 47, 61, 70, 95, 96 💬
18 Ianalumab 💬1件: Ianalumab1件: Ianalumab1件: TNFRSF13C 💬 5件: Cytokine-cytokine receptor interaction, Human T-cell leukemia virus 1 infection, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Primary immunodeficiency 💬8件: 35, 46, 49, 51, 53, 61, 63, 95 💬
19 Infliximab 💬1件: Infliximab1件: Infliximab1件: TNF 💬 66件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬24件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 95, 96, 97, 98, 164, 269, 270, 271 💬
20 Methylprednisolone 💬1件: Methylprednisolone3件: Methylprednisolon; Methylprednisolone; Methylprednisolone acetate1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬45件: 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 96, 97, 127, 162, 164, 222, 224, 271, 283, 284, 285, 296, 300 💬
21 Methylprednisolone acetate 💬1件: Methylprednisolone3件: Methylprednisolon; Methylprednisolone; Methylprednisolone acetate1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬45件: 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 96, 97, 127, 162, 164, 222, 224, 271, 283, 284, 285, 296, 300 💬
22 Mycophenolate mofetil 💬1件: Mycophenolate mofetil1件: Mycophenolate mofetil2件: IMPDH,
IMPDH 💬
2件: Drug metabolism - other enzymes, Purine metabolism 💬32件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 46, 49, 51, 53, 60, 62, 63, 65, 66, 93, 95, 96, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
23 Mycophenolate mofetil hydrochloride 💬1件: Mycophenolate mofetil1件: Mycophenolate mofetil2件: IMPDH,
IMPDH 💬
2件: Drug metabolism - other enzymes, Purine metabolism 💬32件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 46, 49, 51, 53, 60, 62, 63, 65, 66, 93, 95, 96, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
24 Mycophenolate sodium 💬1件: Mycophenolic acid5件: Acido micofenolico; Micofenolico acido; Mycophenolate; Mycophenolate sodium; Mycophenolic acid2件: IMPDH,
IMPDH 💬
2件: Drug metabolism - other enzymes, Purine metabolism 💬12件: 11, 43, 49, 51, 53, 60, 66, 84, 96, 162, 222, 228 💬
25 Mycophenolic acid 💬1件: Mycophenolic acid5件: Acido micofenolico; Micofenolico acido; Mycophenolate; Mycophenolate sodium; Mycophenolic acid2件: IMPDH,
IMPDH 💬
2件: Drug metabolism - other enzymes, Purine metabolism 💬12件: 11, 43, 49, 51, 53, 60, 66, 84, 96, 162, 222, 228 💬
26 Prednisolone 💬1件: Prednisolone3件: Prednisolona; Prednisolone; Prednisolonum1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬39件: 3, 11, 13, 14, 18, 25, 26, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 54, 56, 60, 63, 64, 66, 81, 84, 85, 96, 97, 113, 145, 162, 222, 251, 269, 271, 296, 299, 300 💬
27 Prednisone 💬1件: Prednisone2件: Prednisona; Prednisone1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬54件: 2, 11, 13, 14, 18, 19, 26, 28, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 60, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 90, 93, 95, 96, 97, 113, 145, 162, 164, 205, 222, 224, 228, 251, 269, 283, 285, 288, 299, 300, 303, 307, 331 💬
28 Risedronate sodium 💬1件: Risedronic acid3件: Risedronate; Risedronate sodium; Risedronic acid1件: FDPS 💬 3件: Human T-cell leukemia virus 1 infection, Influenza A, Terpenoid backbone biosynthesis 💬9件: 46, 50, 66, 93, 95, 96, 107, 113, 274 💬
29 Risedronate sodium monohydrate 💬1件: Risedronic acid3件: Risedronate; Risedronate sodium; Risedronic acid1件: FDPS 💬 3件: Human T-cell leukemia virus 1 infection, Influenza A, Terpenoid backbone biosynthesis 💬9件: 46, 50, 66, 93, 95, 96, 107, 113, 274 💬
30 Risedronic acid 💬1件: Risedronic acid3件: Risedronate; Risedronate sodium; Risedronic acid1件: FDPS 💬 3件: Human T-cell leukemia virus 1 infection, Influenza A, Terpenoid backbone biosynthesis 💬9件: 46, 50, 66, 93, 95, 96, 107, 113, 274 💬
31 Siplizumab 💬1件: Siplizumab1件: Siplizumab1件: CD2 💬 2件: Cell adhesion molecules, Hematopoietic cell lineage 💬2件: 94, 95 💬
32 Tacrolimus 💬1件: Tacrolimus1件: Tacrolimus5件: PPP3C,
PPP3C,
PPP3C,
PPP3R,
PPP3R 💬
33件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬31件: 2, 6, 11, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 234, 283, 284, 285, 286 💬
33 Tacrolimus 💬1件: Tacrolimus1件: Tacrolimus5件: PPP3C,
PPP3C,
PPP3C,
PPP3R,
PPP3R 💬
33件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬31件: 2, 6, 11, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 234, 283, 284, 285, 286 💬
34 Ursodiol 💬1件: Ursodeoxycholic acid3件: Udca; Ursodeoxycholic acid; Ursodiol1件: NR1H4 💬 1件: Bile secretion 💬13件: 6, 8, 20, 67, 84, 93, 94, 95, 96, 97, 234, 296, 299 💬
35 Zetomipzomib 💬1件: Zetomipzomib0件: 2件: PSMB8,
PSMB9 💬
1件: Proteasome 💬-
36 Zetomipzomib maleate 💬1件: Zetomipzomib0件: 2件: PSMB8,
PSMB9 💬
1件: Proteasome 💬-
37 Zoledronate disodium 💬1件: Zoledronic acid3件: Zoledronate; Zoledronic acid; Zoledronic acid monohydrate1件: FDPS 💬 3件: Human T-cell leukemia virus 1 infection, Influenza A, Terpenoid backbone biosynthesis 💬14件: 6, 13, 46, 65, 75, 77, 93, 95, 96, 97, 270, 274, 299, 333 💬
38 Zoledronate trisodium 💬1件: Zoledronic acid3件: Zoledronate; Zoledronic acid; Zoledronic acid monohydrate1件: FDPS 💬 3件: Human T-cell leukemia virus 1 infection, Influenza A, Terpenoid backbone biosynthesis 💬14件: 6, 13, 46, 65, 75, 77, 93, 95, 96, 97, 270, 274, 299, 333 💬
39 Zoledronic acid 💬1件: Zoledronic acid3件: Zoledronate; Zoledronic acid; Zoledronic acid monohydrate1件: FDPS 💬 3件: Human T-cell leukemia virus 1 infection, Influenza A, Terpenoid backbone biosynthesis 💬14件: 6, 13, 46, 65, 75, 77, 93, 95, 96, 97, 270, 274, 299, 333 💬
40 Zoledronic acid 💬1件: Zoledronic acid3件: Zoledronate; Zoledronic acid; Zoledronic acid monohydrate1件: FDPS 💬 3件: Human T-cell leukemia virus 1 infection, Influenza A, Terpenoid backbone biosynthesis 💬14件: 6, 13, 46, 65, 75, 77, 93, 95, 96, 97, 270, 274, 299, 333 💬
41 Zoledronic acid hemipentahydrate 💬1件: Zoledronic acid3件: Zoledronate; Zoledronic acid; Zoledronic acid monohydrate1件: FDPS 💬 3件: Human T-cell leukemia virus 1 infection, Influenza A, Terpenoid backbone biosynthesis 💬14件: 6, 13, 46, 65, 75, 77, 93, 95, 96, 97, 270, 274, 299, 333 💬