Target Gene/Pathway Pathway / Gene

  

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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 ATP1A1 💬 19件: cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Cytoskeleton in muscle cells, Insulin secretion, Thyroid hormone synthesis, Thyroid hormone signaling pathway, Aldosterone synthesis and secretion, Aldosterone-regulated sodium reabsorption, Endocrine and other factor-regulated calcium reabsorption, Proximal tubule bicarbonate reclamation, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Carbohydrate digestion and absorption, Protein digestion and absorption, Bile secretion, Mineral absorption Digitoxin 💬 Digitoxin 1件: 299 💬
2 ATP1A1 💬 19件: cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Cytoskeleton in muscle cells, Insulin secretion, Thyroid hormone synthesis, Thyroid hormone signaling pathway, Aldosterone synthesis and secretion, Aldosterone-regulated sodium reabsorption, Endocrine and other factor-regulated calcium reabsorption, Proximal tubule bicarbonate reclamation, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Carbohydrate digestion and absorption, Protein digestion and absorption, Bile secretion, Mineral absorption Digoxin 💬 Digoxin 7件: 2, 8, 46, 57, 65, 67, 210 💬
3 ATP1A2 💬 19件: cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Cytoskeleton in muscle cells, Insulin secretion, Thyroid hormone synthesis, Thyroid hormone signaling pathway, Aldosterone synthesis and secretion, Aldosterone-regulated sodium reabsorption, Endocrine and other factor-regulated calcium reabsorption, Proximal tubule bicarbonate reclamation, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Carbohydrate digestion and absorption, Protein digestion and absorption, Bile secretion, Mineral absorption Digitoxin 💬 Digitoxin 1件: 299 💬
4 ATP1A2 💬 19件: cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Cytoskeleton in muscle cells, Insulin secretion, Thyroid hormone synthesis, Thyroid hormone signaling pathway, Aldosterone synthesis and secretion, Aldosterone-regulated sodium reabsorption, Endocrine and other factor-regulated calcium reabsorption, Proximal tubule bicarbonate reclamation, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Carbohydrate digestion and absorption, Protein digestion and absorption, Bile secretion, Mineral absorption Digoxin 💬 Digoxin 7件: 2, 8, 46, 57, 65, 67, 210 💬
5 ATP1A3 💬 19件: cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Cytoskeleton in muscle cells, Insulin secretion, Thyroid hormone synthesis, Thyroid hormone signaling pathway, Aldosterone synthesis and secretion, Aldosterone-regulated sodium reabsorption, Endocrine and other factor-regulated calcium reabsorption, Proximal tubule bicarbonate reclamation, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Carbohydrate digestion and absorption, Protein digestion and absorption, Bile secretion, Mineral absorption Digoxin 💬 Digoxin 7件: 2, 8, 46, 57, 65, 67, 210 💬
6 ATP1A3 💬 19件: cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Cytoskeleton in muscle cells, Insulin secretion, Thyroid hormone synthesis, Thyroid hormone signaling pathway, Aldosterone synthesis and secretion, Aldosterone-regulated sodium reabsorption, Endocrine and other factor-regulated calcium reabsorption, Proximal tubule bicarbonate reclamation, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Carbohydrate digestion and absorption, Protein digestion and absorption, Bile secretion, Mineral absorption Digitoxin 💬 Digitoxin 1件: 299 💬
7 ATP1A4 💬 19件: cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Cytoskeleton in muscle cells, Insulin secretion, Thyroid hormone synthesis, Thyroid hormone signaling pathway, Aldosterone synthesis and secretion, Aldosterone-regulated sodium reabsorption, Endocrine and other factor-regulated calcium reabsorption, Proximal tubule bicarbonate reclamation, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Carbohydrate digestion and absorption, Protein digestion and absorption, Bile secretion, Mineral absorption Digitoxin 💬 Digitoxin 1件: 299 💬
8 ATP1A4 💬 19件: cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Cytoskeleton in muscle cells, Insulin secretion, Thyroid hormone synthesis, Thyroid hormone signaling pathway, Aldosterone synthesis and secretion, Aldosterone-regulated sodium reabsorption, Endocrine and other factor-regulated calcium reabsorption, Proximal tubule bicarbonate reclamation, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Carbohydrate digestion and absorption, Protein digestion and absorption, Bile secretion, Mineral absorption Digoxin 💬 Digoxin 7件: 2, 8, 46, 57, 65, 67, 210 💬
9 COL7A1 💬 2件: Cornified envelope formation, Protein digestion and absorption Beremagene geperpavec 💬 Beremagene geperpavec 1件: 36 💬
10 CTRB1 💬 2件: Pancreatic secretion, Protein digestion and absorption Ulinastatin 💬 Ulinastatin 1件: 70 💬
11 CTRB2 💬 2件: Pancreatic secretion, Protein digestion and absorption Ulinastatin 💬 Ulinastatin 1件: 70 💬
12 DPP4 💬 2件: Virion - Hepatitis viruses, Protein digestion and absorption Saxagliptin hydrochloride 💬 Saxagliptin 1件: 299 💬
13 DPP4 💬 2件: Virion - Hepatitis viruses, Protein digestion and absorption Sitagliptin 💬 Sitagliptin 6件: 6, 63, 75, 77, 233, 299 💬
14 DPP4 💬 2件: Virion - Hepatitis viruses, Protein digestion and absorption Vildagliptin 💬 Vildagliptin 1件: 6 💬
15 DPP4 💬 2件: Virion - Hepatitis viruses, Protein digestion and absorption Saxagliptin 💬 Saxagliptin 1件: 299 💬
16 DPP4 💬 2件: Virion - Hepatitis viruses, Protein digestion and absorption Sitagliptin phosphate 💬 Sitagliptin 6件: 6, 63, 75, 77, 233, 299 💬
17 DPP4 💬 2件: Virion - Hepatitis viruses, Protein digestion and absorption Sitagliptin phosphate 💬 Sitagliptin 6件: 6, 63, 75, 77, 233, 299 💬
18 KCNN4 💬 4件: Insulin secretion, GnRH secretion, Salivary secretion, Protein digestion and absorption Senicapoc 💬 Senicapoc 1件: 85 💬
19 KCNQ1 💬 6件: Adrenergic signaling in cardiomyocytes, Cholinergic synapse, Gastric acid secretion, Pancreatic secretion, Protein digestion and absorption, Vibrio cholerae infection Ezogabine 💬 Ezogabine 2件: 2, 144 💬
20 KCNQ1 💬 6件: Adrenergic signaling in cardiomyocytes, Cholinergic synapse, Gastric acid secretion, Pancreatic secretion, Protein digestion and absorption, Vibrio cholerae infection Amiodarone 💬 Amiodarone 3件: 28, 67, 127 💬
21 KCNQ1 💬 6件: Adrenergic signaling in cardiomyocytes, Cholinergic synapse, Gastric acid secretion, Pancreatic secretion, Protein digestion and absorption, Vibrio cholerae infection Amiodarone hydrochloride 💬 Amiodarone 3件: 28, 67, 127 💬
22 MME 💬 4件: Renin-angiotensin system, Hematopoietic cell lineage, Protein digestion and absorption, Alzheimer disease Sacubitril 💬 Sacubitril 4件: 28, 58, 210, 222 💬
23 PRSS1 💬 4件: Neuroactive ligand-receptor interaction, Pancreatic secretion, Protein digestion and absorption, Influenza A Ulinastatin 💬 Ulinastatin 1件: 70 💬
24 PRSS2 💬 4件: Neuroactive ligand-receptor interaction, Pancreatic secretion, Protein digestion and absorption, Influenza A Ulinastatin 💬 Ulinastatin 1件: 70 💬
25 PRSS3 💬 4件: Neuroactive ligand-receptor interaction, Pancreatic secretion, Protein digestion and absorption, Influenza A Ulinastatin 💬 Ulinastatin 1件: 70 💬
26 SLC9A3 💬 4件: Proximal tubule bicarbonate reclamation, Protein digestion and absorption, Bile secretion, Mineral absorption Tenapanor hydrochloride 💬 Tenapanor 2件: 6, 299 💬
27 SLC9A3 💬 4件: Proximal tubule bicarbonate reclamation, Protein digestion and absorption, Bile secretion, Mineral absorption Tenapanor 💬 Tenapanor 2件: 6, 299 💬