Target Gene/Pathway Pathway / Gene


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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 COMT 💬 3件: Steroid hormone biosynthesis, Tyrosine metabolism, Dopaminergic synapse Entacapone 💬 Entacapone 2件: 6, 17 💬
2 COMT 💬 3件: Steroid hormone biosynthesis, Tyrosine metabolism, Dopaminergic synapse Opicapone 💬 Opicapone 1件: 6 💬
3 COMT 💬 3件: Steroid hormone biosynthesis, Tyrosine metabolism, Dopaminergic synapse Tolcapone 💬 Tolcapone 3件: 6, 28, 127 💬
4 CYP11A 💬 5件: Steroid hormone biosynthesis, Ovarian steroidogenesis, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome Levoketoconazole 💬 Levoketoconazole 1件: 75 💬
5 CYP11B1 💬 3件: Steroid hormone biosynthesis, Cortisol synthesis and secretion, Cushing syndrome Metyrapone 💬 Metyrapone 1件: 75 💬
6 CYP11B1 💬 3件: Steroid hormone biosynthesis, Cortisol synthesis and secretion, Cushing syndrome Levoketoconazole 💬 Levoketoconazole 1件: 75 💬
7 CYP11B2 💬 2件: Steroid hormone biosynthesis, Aldosterone synthesis and secretion Osilodrostat 💬 Osilodrostat 1件: 75 💬
8 CYP11B2 💬 2件: Steroid hormone biosynthesis, Aldosterone synthesis and secretion Osilodrostat phosphate 💬 Osilodrostat 1件: 75 💬
9 CYP17A 💬 5件: Steroid hormone biosynthesis, Ovarian steroidogenesis, Prolactin signaling pathway, Cortisol synthesis and secretion, Cushing syndrome Abiraterone acetate 💬 Abiraterone 2件: 75, 81 💬
10 CYP17A 💬 5件: Steroid hormone biosynthesis, Ovarian steroidogenesis, Prolactin signaling pathway, Cortisol synthesis and secretion, Cushing syndrome Levoketoconazole 💬 Levoketoconazole 1件: 75 💬
11 CYP19A 💬 2件: Steroid hormone biosynthesis, Ovarian steroidogenesis Letrozole 💬 Letrozole 2件: 81, 89 💬
12 CYP19A 💬 2件: Steroid hormone biosynthesis, Ovarian steroidogenesis Anastrozole 💬 Anastrozole 3件: 78, 86, 193 💬
13 HSD11B1 💬 3件: Steroid hormone biosynthesis, Metabolism of xenobiotics by cytochrome P450, Chemical carcinogenesis - DNA adducts Dipotassium glycyrrhizinate 💬 Glycyrrhizic acid 2件: 46, 51 💬
14 SRD5A1 💬 1件: Steroid hormone biosynthesis Dutasteride 💬 Dutasteride 2件: 1, 2 💬
15 SRD5A2 💬 2件: Steroid hormone biosynthesis, Prostate cancer Finasteride 💬 Finasteride 1件: 6 💬
16 SRD5A2 💬 2件: Steroid hormone biosynthesis, Prostate cancer Dutasteride 💬 Dutasteride 2件: 1, 2 💬